Edwards, Darren

Team Leader, Biological Chemistry and Drug Discovery

Source: Scopus
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40 Citations
2 h-Index
4 Article

Discovery of an Allosteric Binding Site in Kinetoplastid Methionyl-tRNA Synthetase
Torrie, L. S., Robinson, D. A., Thomas, M. G., Hobrath, J. V., Shepherd, S. M., Post, J. M., Ko, E. J., Ferreira, R. A., Mackenzie, C. J., Wrobel, K., Edwards, D. P., Gilbert, I. H., Gray, D. W., Fairlamb, A. H. & De Rycker, M., 8 May 2020, In: ACS Infectious Diseases. 6, 5, p. 1044-1057 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
1 Citation (Scopus)

13 Downloads (Pure)
Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs
Giordani, F., Paape, D., Vincent, I. M., Pountain, A. W., Fernández-Cortés, F., Rico, E., Zhang, N., Morrison, L. J., Freund, Y., Witty, M. J., Peter, R., Edwards, D. Y., Wilkes, J. M., van der Hooft, J. J. J., Regnault, C., Read, K. D., Horn, D., Field, M. C. & Barrett, M. P., 3 Nov 2020, In: PLoS Pathogens. 16, 11, 20 p., e1008932.
Research output: Contribution to journal › Article › peer-review

Open Access
File
2 Downloads (Pure)
Rapid and scale-independent microfluidic manufacture of liposomes entrapping protein incorporating in-line purification and at-line size monitoring
Forbes, N., Hussain, M. T., Briuglia, M. L., Edwards, D. Y., Horst, J. H. T., Szita, N. & Perrie, Y., 10 Feb 2019, In: International Journal of Pharmaceutics. 556, p. 68-81 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
35 Citations (Scopus)

120 Downloads (Pure)
Chromatographic retention behaviour, modelling and optimization of a UHPLC-UV separation of the regioisomers of the Novel Psychoactive Substance (NPS) methoxphenidine (MXP)
Boateng, B. O., Fever, M., Edwards, D., Petersson, P., Euerby, M. R. & Sutcliffe, O. B., 10 May 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 153, p. 238-247 10 p.
Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus)

Discovery of an Allosteric Binding Site in Kinetoplastid Methionyl-tRNA Synthetase

Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs

Rapid and scale-independent microfluidic manufacture of liposomes entrapping protein incorporating in-line purification and at-line size monitoring

Chromatographic retention behaviour, modelling and optimization of a UHPLC-UV separation of the regioisomers of the Novel Psychoactive Substance (NPS) methoxphenidine (MXP)