Gray, David

Projects

Projects per year 2011 2017 2018 2019 2025

• 2 Not started
• 9 Active
• 18 Finished

Projects per year

Search results

• Active

  MRC IAA 2021 University of Dundee

  Ferguson, M., Gilbert, I., Gray, D. & Read, K.

  Medical Research Council

  1/04/22 → 31/03/25

  Project: Research

• Refining the Drug Discovery Paradigm for Schistosomiasis (Joint with the Universities of Aberystwyth & Cardiff)

  Gilbert, I., Gray, D., Read, K. & Wyatt, P.

  Wellcome Trust

  1/10/21 → 1/04/24

  Project: Research

• Optimisation of Multistage Inhibitors of P. Falciparum Lysyl-t-RNA Synthetase for the Treatment of Malaria (joint with Eisai Pharmaceuticals and Medicines for Malaria Venture)

  Gilbert, I., Gray, D., Read, K. & Wyatt, P.

  1/04/21 → 31/07/23

  Project: Research

• Dundee - Confidence in Concept 2019

  Brady, J., Brady, J., Ferguson, M., Gray, D. & Wyatt, P.

  Medical Research Council

  31/03/20 → 1/04/23

  Project: Research

• A Drug Target for Shigella (Open Lab Programme)

  Gilbert, I., Gray, D. & Read, K.

  17/10/19 → 16/02/23

  Project: Research

• Development of New Agents for the Treatment of Cryptosporidiosis (DPFS) (Joint with University of Vermont)

  Gilbert, I., Gray, D., Pawlowic, M., Read, K. & Wyatt, P.

  Medical Research Council

  1/05/19 → 31/01/23

  Project: Research

• Structure-Guided Drug Discovery for Malaria and Tuberculosis (joint with Structural Genomics Consortium)

  Gilbert, I., Gray, D., Read, K. & Wyatt, P.

  Bill and Melinda Gates Foundation

  1/01/19 → 6/07/24

  Project: Research

  • Lysine-tRNA Ligase 100%
  • Plasmodium falciparum 59%
  • Proteome 59%
  • Drug Discovery 58%
  • Hot Temperature 44%

• KRS Inhibitors: A Dundee Mini Portfolio

  Gilbert, I., Gray, D., Read, K. & Wyatt, P.

  1/01/18 → 31/12/22

  Project: Research

• Wellcome Centre for Anti-Infectives Research

  Cook, S., De Rycker, M., Fairlamb, A., Ferguson, M., Field, M., Gilbert, I., Gray, D., Horn, D., Pawlowic, M., Read, K., Wyatt, P. & Wyllie, S.

  Wellcome Trust

  1/04/17 → 31/03/24

  Project: Research

  • Drug Discovery 100%
  • Trypanosoma 75%
  • Parasites 67%
  • Trypanosoma brucei brucei 66%
  • Trypanosoma cruzi 64%
• Not started

  Acclerate China-UK AMR Discovery: Establishing and Exploiting a Joint UK/China Platform to Enable High Throughput Structure and Fragment Based AMR Training and Discovery (Joint with University of Warwick)

  Gilbert, I. & Gray, D.

  Project: Research

• A Pipeline of Drugs for Visceral Leishmaniasis and Chagas Disease Through Expertise and Innovation (Preliminary Strategic Award) (Joint with Glaxosmithkline)

  Fairlamb, A., Ferguson, M., Field, M., Gilbert, I., Gray, D., Horn, D., Read, K. & Wyatt, P.

  Project: Research

• Finished

  Early Stage Challenge Fund Application - HGSP Covid Response RNACapRx (High Growth Spin Out Programme)

  Cowling, V. & Gray, D.

  14/09/20 → 31/03/21

  Project: Research

• PPM1H Activators for Treatment of Parkinson's Disease

  Alessi, D. & Gray, D.

  1/09/19 → 30/03/21

  Project: Research

• The Innovative Targets Portfolio: Basic Life Sciences Research to Novel Therapies, through a Portfolio of Small Molecule Translational Projects

  Ferguson, M., Gray, D. & Wyatt, P.

  Medical Research Council

  1/07/19 → 30/06/22

  Project: Research

  • rapidFire Mass Spectrometry 100%
  • SARS Virus 84%
  • Single-Domain Antibodies 72%
  • High-Throughput Screening Assays 69%
  • Severe Acute Respiratory Syndrome 63%

• Drug Discovery Collaboration - Tau Seeding

  Gray, D.

  1/03/19 → 30/11/21

  Project: Research

• Developing Small Molecule Cancer Therapeutics Targeting the RNA Splicing Machinery: Target Validation on STRAP/UNRIP

  Gray, D., Lamond, A., Petty, R. & Wyatt, P.

  Cancer Research UK

  1/10/18 → 31/12/20

  Project: Research

• MRC Confidence in Concept 2018

  Ferguson, M., Gray, D. & Wyatt, P.

  Medical Research Council

  1/03/18 → 29/02/20

  Project: Research

  • Neuroepithelial Cells 100%
  • Oncogenes 65%
  • Nucleotide 56%
  • Heterodimer 52%
  • Guanine 44%

• Targeting the Neuroepithelial Transforming Gene 1 (NET1)-PH/RhoA Interface to Fight the Invasive Phenotype of the Gastric Adenocarcinoma

  Gray, D. & Petit, A.

  6/03/17 → 5/03/18

  Project: Research

• The Innovative Targets Portfolio: Basic Life Sciences Research to Novel Therapies, through a Portfolio of Small Molecule Translational Projects

  Ferguson, M., Gray, D. & Wyatt, P.

  Medical Research Council

  1/03/17 → 28/02/19

  Project: Research

• SHORTEN-TB: Developing Leads to Shorten Duration of TB Chemotherapy (Joint with NIH NIAD, University of Cambridge, University of Cape Town Braunschweig Germany)

  Gilbert, I., Gray, D., Read, K. & Wyatt, P.

  National Institutes of Health

  23/01/17 → 22/01/20

  Project: Research

• Hit Discovery for Schistosomiasis (Pathfinder) (Joint with University of Aberystwyth)

  Gilbert, I., Gray, D. & Read, K.

  Wellcome Trust

  1/07/16 → 30/06/19

  Project: Research

• Innovative Targets Portfolio: Basic Life Sciences Research to Novel Therapies, through a Portfolio of Small Molecule Translational Projects (Confidence in Concept)

  Ferguson, M., Gray, D. & Wyatt, P.

  Medical Research Council

  1/03/16 → 28/02/18

  Project: Research

  • Neuroepithelial Cells 100%
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry 82%
  • Oncogenes 65%
  • Salts 60%
  • Nucleotide 56%

• High Throughput Biolayer Interferometry at Dundee for Anti-Microbial and Interaction Studies

  Birch, P., Ciulli, A., Fairlamb, A., Gray, D., Hunter, B., Owen-Hughes, T., Palmer, T., Ryan, R., Sargent, F., Stanley-Wall, N. & van Aalten, D.

  Biotechnology and Biological Sciences Research Council

  22/01/15 → 21/01/16

  Project: Research

• Chemical Biology: Leveraging Phenotypic Hits Against Kinetoplastids (Strategic Grant)

  Fairlamb, A., Field, M., Gilbert, I., Gray, D., Horn, D. & Wyatt, P.

  Wellcome Trust

  1/01/15 → 31/12/20

  Project: Research

  • Visceral Leishmaniasis 100%
  • Pharmaceutical Preparations 90%
  • Leishmania donovani 80%
  • Nitroreductases 78%
  • Drug Discovery 77%

• Knowledge Transfer Partnership with MicroMatrices - Industrial Partner

  Gray, D.

  1/09/13 → 1/09/16

  Project: Research

• A Centre of Excellence for Lead Optimisation for Diseases of the Developing World (Joint funding by Wellcome & Gates)

  Gilbert, I., Gray, D., Read, K. & Wyatt, P.

  Wellcome Trust

  1/07/13 → 31/10/18

  Project: Research

  • TAM16 compound 100%
  • Tuberculosis 77%
  • Lysine-tRNA Ligase 73%
  • benzofuran 67%
  • Benznidazole 66%

• Developing an Assay to Implement Screening for Differentiation-Inducing and/or Cytotoxic Agents of Cancer Stem Cells for the Potential Development of Pancreatic Cancer Therapeutics

  Gray, D. & McElroy, S.

  1/02/12 → 31/07/13

  Project: Research

• Accelerating Drug Discovery into Therapeutics and Commercial Benefit (Horizon Fund)

  Gray, D., Hopkins, A., Read, K., Woodland, A. & Wyatt, P.

  1/11/11 → 31/12/13

  Project: Research

• Discovery and Development of Drug Candidates for Neglected Diseases (joint with industrial partner)

  Brenk, R., Fairlamb, A., Ferguson, M., Field, M., Gilbert, I., Gray, D., Hopkins, A., Horn, D., Read, K., Wyatt, P. & van Aalten, D.

  Wellcome Trust

  1/02/11 → 1/07/17

  Project: Research

  • Trypanosoma brucei brucei 100%
  • glycylpeptide N-tetradecanoyltransferase 97%
  • Visceral Leishmaniasis 90%
  • Trypanosoma cruzi 81%
  • Leishmania donovani 64%