Projects per year
Fingerprint Dive into the research topics where David Horn is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 57 Similar Profiles
Trypanosomiasis
Medicine & Life Sciences
Trypanosoma brucei brucei
Medicine & Life Sciences
Parasites
Medicine & Life Sciences
Membrane Glycoproteins
Medicine & Life Sciences
Melarsoprol
Medicine & Life Sciences
Pentamidine
Medicine & Life Sciences
Pharmaceutical Preparations
Medicine & Life Sciences
African Trypanosomiasis
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2013 2025
Mode of Action Studies in Kinetoplastid Parasites (Industrial CASE Studentship)
1/09/17 → 30/09/21
Project: Research
Wellcome Centre for Anti-Infectives Research
Cook, S., Fairlamb, A., Ferguson, M., Field, M., Gilbert, I., Gray, D., Horn, D., Read, K. & Wyatt, P.
1/04/17 → 31/03/22
Project: Research
Chemical Biology: Leveraging Phenotypic Hits Against Kinetoplastids (Strategic Grant)
Fairlamb, A., Field, M., Gilbert, I., Gray, D., Horn, D. & Wyatt, P.
1/01/15 → 30/06/20
Project: Research
High-Throughput Decoding of Virulence Mechanisms in African Trypanosomes (Senior Investigator Award)
1/09/13 → 29/02/20
Project: Research
Research Output 2008 2019
A post-transcriptional respiratome regulon in trypanosomes
Trenaman, A., Glover, L., Hutchinson, S. & Horn, D., 26 Jul 2019, In : Nucleic Acids Research. 47, 13, p. 7063-7077 15 p.Research output: Contribution to journal › Article
Open Access
File
Regulon
Trypanosomiasis
Membrane Glycoproteins
Trypanosoma brucei brucei
RNA-Binding Proteins
Chemogenomic Profiling of Antileishmanial Efficacy and Resistance in the Related Kinetoplastid Parasite Trypanosoma brucei
Collett, C. F., Kitson, C., Baker, N., Steele-Stallard, H. B., Santrot, M-V., Hutchinson, S., Horn, D. & Alsford, S., Aug 2019, In : Antimicrobial Agents and Chemotherapy. 63, 8, p. 1-19 19 p., e00795-19.Research output: Contribution to journal › Article
Open Access
File
Trypanosoma brucei brucei
miltefosine
Parasites
Pharmaceutical Preparations
Leishmania
Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex
Correia Faria, J., Glover, L., Hutchinson, S., Boehm, C., Field, M. C. & Horn, D., 9 Jul 2019, In : Nature Communications. 10, p. 1-14 14 p., 3023.Research output: Contribution to journal › Article
Open Access
File
Trypanosoma Variant Surface Glycoproteins
Trypanosoma brucei brucei
Membrane Glycoproteins
exclusion
Epigenomics
Persistent DNA Damage Foci and DNA Replication with a Broken Chromosome in the African Trypanosome
Glover, L., Marques, C., Suska, O. & Horn, D., 9 Jul 2019, In : MBio. 10, 4, p. 1-17 17 p., e01252-19.Research output: Contribution to journal › Article
Open Access
File
Trypanosomiasis
DNA Replication
DNA Damage
Replication Protein A
Chromosomes
Pharmacological validation of N-myristoyltransferase as a drug target in Leishmania donovani
Corpas Lopez, V., Moniz, S., Thomas, M., Wall, R., Torrie, L., Zander-Dinse, D., Tinti, M., Brand, S., Stojanovski, L., Manthri, S., Hallyburton, I., Zuccotto, F., Wyatt, P., De Rycker, M., Horn, D., Ferguson, M., Clos, J., Read, K., Fairlamb, A., Gilbert, I. & 1 others, , 11 Jan 2019, In : ACS Infectious Diseases. 5, 1, p. 111-122 12 p.Research output: Contribution to journal › Article
Open Access
File
Leishmania donovani
Pharmacology
Parasites
Enzymes
Pharmaceutical Preparations
Press / Media
Sleeping sickness parasite's pores act as efficient drug uptake mechanism
26/11/13
3 items of Media coverage
Press/Media: Research
Thesis
African Trypanosome Genes Specifically Required for Fitness in vivo
Author: Shrimpton, J. W., 2017Supervisor: Horn, D. (Supervisor)
Student thesis: Master's Thesis › Master of Science
File
Folate transport and drug resistance in the African Trypanosome
Author: Dewar, S., 2017Supervisor: Fairlamb, A. (Supervisor) & Horn, D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
VSG expression in African trypanosomes: Gene silencing, cell cycle and developmental control
Author: Hutchinson, S. J., 2016Supervisor: Horn, D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy