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Lilley, David

Professor

 https://orcid.org/0000-0001-6882-2818

  • United Kingdom

20002021
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  • 7 Similar Profiles
Catalytic RNA Medicine & Life Sciences
RNA Medicine & Life Sciences
Riboswitch Medicine & Life Sciences
Cruciform DNA Medicine & Life Sciences
Deoxyribonuclease I Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Ions Medicine & Life Sciences
Adenine Medicine & Life Sciences

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Projects 2012 2021

Processing of Branched DNA Molecules During Cytokinesis, Uncovering New Mechanisms of Genome Maintenance

Gartner, A., Lilley, D. & Rouse, J.

Biotechnology and Biological Sciences Research Council

1/12/18 → 30/11/21

Project: Research

Dynamics of Eukaryotic Junction-Resolving Enzyme GEN1 - DNA Junction Interactions

Lilley, D.

Biotechnology and Biological Sciences Research Council

1/10/16 → 30/09/19

Project: Research

The Nucleic Acid Structure Research Group

Lilley, D.

Cancer Research UK

1/01/16 → 31/12/20

Project: Research

Cancer Research-UK Nucleic Acid Structure Research Group: Nucleic Acid Structure and Interactions with Proteins (Programme Grants Years 4 and 5)

Lilley, D.

Project: Research

State of the Art Pulse EPR Instrumentation for Long Range Distance Measurements in Biomacromolecules (Multi-User Equipment Grant) (Joint with University of St Andrews)

Hunter, B., Keeble, D., Lilley, D., Norman, D. & Owen-Hughes, T.

Wellcome Trust

24/09/12 → 23/09/17

Project: Research

Research Output 2000 2019

4 Downloads (Pure)

Classification of the nucleolytic ribozymes based upon catalytic mechanism

Lilley, D. M. J., 19 Aug 2019, In : F1000Research. 8, p. 1-10 10 p., 1462.

Research output: Contribution to journal › Review article

Open Access
File
Catalytic RNA
Catalysis
RNA Cleavage
Acids
Hydroxyl Radical
22 Downloads (Pure)

Comparison of the Structures and Mechanisms of the Pistol and Hammerhead Ribozymes

Wilson, T. J., Liu, Y., Li, N-S., Dai, Q., Piccirilli, J. A. & Lilley, D. M. J., 2019, In : Journal of the American Chemical Society. 141, 19, p. 7865-7875 11 p.

Research output: Contribution to journal › Article

Open Access
File
Catalytic RNA
Conformations
Nucleophiles
Acids
Metal ions
21 Downloads (Pure)

Effect of methylation of adenine N6 on kink turn structure depends on location

Ashraf, S., Huang, L. & Lilley, D., 24 Jun 2019, In : RNA Biology. 9 p.

Research output: Contribution to journal › Article

Open Access
File
Adenine
Protein Binding
Base Pairing
Methylation
RNA Folding
14 Downloads (Pure)

Junction resolving enzymes use multivalency to keep the Holliday junction dynamic

Zhou, R., Yang, O., Declais, A-C., Jin, H., Gwon, G. H., Freeman, A., Cho, Y., Lilley, D. & Ha, T., 1 Mar 2019, In : Nature Chemical Biology. 15, 3, p. 269-275 7 p.

Research output: Contribution to journal › Article

Open Access
File
Cruciform DNA
Enzymes
Genetic Recombination
Bacteriophage T7
Chromosome Segregation
39 Downloads (Pure)

Structure and ligand binding of the glutamine-II riboswitch

Huang, L., Wang, J., Watkins, A. M., Das, R. & Lilley, D. M. J., 19 Jun 2019, In : Nucleic Acids Research. 10 p., gkz539.

Research output: Contribution to journal › Article

Open Access
File
Riboswitch
Glutamine
RNA
Ligands
Binding Sites

Thesis

Sequence Dependence of the Folding of Kink-Turns in RNA

Author: Ashraf, S., 2017

Supervisor: Lilley, D. (Supervisor)

Student thesis: Master's Thesis › Master of Science

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