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Vara Ciruelos, Diana

Dr

  • 54 Citations
  • 4 h-Index
20162019
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AMP-Activated Protein Kinases Medicine & Life Sciences
Phenformin Chemical Compounds
Prostatic Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Neuroendocrine Cells Medicine & Life Sciences
Cell Survival Medicine & Life Sciences
T-cells Chemical Compounds
Neoplastic Stem Cells Medicine & Life Sciences

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Research Output 2016 2019

  • 54 Citations
  • 4 h-Index
  • 7 Article
50 Downloads (Pure)

Phenformin, but not metformin, delays development of T-cell acute lymphoblastic leukemia/lymphoma via cell-autonomous AMPK activation

Vara Ciruelos, D., Dandapani, M., Russell, F., Grzes, K. M., Atrih, A., Foretz, M., Viollet, B., Lamont, D., Cantrell, D. & Hardie, G., 16 Apr 2019, In : Cell Reports. 27, 3, p. 690-698.e4

Research output: Contribution to journalArticle

Open Access
File
Phenformin
AMP-Activated Protein Kinases
T-cells
Metformin
Precursor Cell Lymphoblastic Leukemia-Lymphoma
40 Downloads (Pure)

Targeting AMP-activated kinase impacts hepatocellular cancer stem cells induced by long-term treatment with sorafenib

Bort, A., Sánchez, B. G., Mateos-Gómez, P. A., Vara-Ciruelos, D., Rodríguez-Henche, N. & Díaz-Laviada, I., May 2019, In : Molecular Oncology. 13, 5, p. 1311-1331 21 p.

Research output: Contribution to journalArticle

Open Access
File
AMP-Activated Protein Kinases
Neoplastic Stem Cells
Liver Neoplasms
Hepatocellular Carcinoma
Stem Cells
1 Citation (Scopus)
18 Downloads (Pure)

The strange case of AMPK and cancer: Dr Jekyll or Mr Hyde? †

Vara-Ciruelos, D., Russell, F. M. & Hardie, D. G., 10 Jul 2019, In : Open Biology. 9, 7, p. 1-21 21 p., 190099.

Research output: Contribution to journalArticle

Open Access
File
AMP-Activated Protein Kinases
Adenosine Monophosphate
Neoplasms
Tumors
DNA Damage
8 Citations (Scopus)
56 Downloads (Pure)

Genotoxic Damage Activates the AMPK-α1 Isoform in the Nucleus via Ca2+/CaMKK2 Signaling to Enhance Tumor Cell Survival

Vara Ciruelos, D., Dandapani, M., Gray, A., Agbani, E. O., Evans, A. M. & Hardie, D. G., Feb 2018, In : Molecular Cancer Research. 16, 2, p. 345-357 13 p.

Research output: Contribution to journalArticle

Open Access
File
AMP-Activated Protein Kinases
Cell Survival
Protein Isoforms
Etoposide
DNA Damage
23 Citations (Scopus)
220 Downloads (Pure)

AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2

Fogarty, S., Ross, F. A., Vara Ciruelos, D., Gray, A., Gowans, G. J. & Hardie, D. G., 1 Aug 2016, In : Molecular Cancer Research. 14, 8, p. 683-695 13 p.

Research output: Contribution to journalArticle

Open Access
File
AMP-Activated Protein Kinases
Cell Cycle Checkpoints
Null Lymphocytes
Phosphorylation
Calcimycin