Murugesan, Dinakaran


  • United Kingdom

  • 101 Citations
  • 5 h-Index
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Fingerprint Dive into the research topics where Dinakaran Murugesan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 32 Similar Profiles
Antimalarials Medicine & Life Sciences
Structure-Activity Relationship Medicine & Life Sciences
Mycobacterium tuberculosis Medicine & Life Sciences
Quinazolinones Medicine & Life Sciences
Indazoles Medicine & Life Sciences
Plasmodium falciparum Medicine & Life Sciences
Inosine Monophosphate Medicine & Life Sciences
Sulfonamides Medicine & Life Sciences

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Research Output 2013 2018

  • 101 Citations
  • 5 h-Index
  • 5 Article
7 Citations (Scopus)
98 Downloads (Pure)

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization

Murugesan, D., Ray, P. C., Bayliss, T., Prosser, G. A., Harrison, J. R., Green, K., Soares De Melo, C., Feng, T. S., Street, L. J., Chibale, K., Warner, D. F., Mizrahi, V., Epemolu, O., Scullion, P., Ellis, L., Riley, J., Shishikura, Y., Ferguson, L., Osuna-Cabello, M., Read, K. D. & 10 others, Green, S. R., Lamprecht, D. A., Steyn, A. J. C., Ioerger, T. R., Sacchettini, J., Rhee, K. Y., Arora, K., Barry, C. E., Wyatt, P. G. & Boshoff, H. I. M., 8 Jun 2018, In : ACS Infectious Diseases. 4, 6, p. 954-969 16 p.

Research output: Contribution to journalArticle

Open Access
Structure-Activity Relationship
Mycobacterium tuberculosis
Adenosine Triphosphate
Allosteric Site
34 Citations (Scopus)

Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis

Park, Y., Pacitto, A., Bayliss, T., Cleghorn, L. A. T., Wang, Z., Hartman, T., Arora, K., Ioerger, T. R., Sacchettini, J., Rizzi, M., Donini, S., Blundell, T. L., Ascher, D. B., Rhee, K., Breda, A., Zhou, N., Dartois, V., Jonnala, S. R., Via, L. E., Mizrahi, V. & 35 others, Epemolu, O., Stojanovski, L., Simeons, F., Osuna-Cabello, M., Ellis, L., MacKenzie, C. J., Smith, A. R. C., Davis, S. H., Murugesan, D., Buchanan, K. I., Turner, P. A., Huggett, M., Zuccotto, F., Rebollo-Lopez, M. J., Lafuente-Monasterio, M. J., Sanz, O., Diaz, G. S., Lelièvre, J., Ballell, L., Selenski, C., Axtman, M., Ghidelli-Disse, S., Pflaumer, H., Bösche, M., Drewes, G., Freiberg, G. M., Kurnick, M. D., Srikumaran, M., Kempf, D. J., Green, S. R., Ray, P. C., Read, K., Wyatt, P., Barry, C. E. & Boshoff, H. I., 13 Jan 2017, In : ACS Infectious Diseases. 3, 1, p. 18-33 16 p.

Research output: Contribution to journalArticle

Inosine Monophosphate
Mycobacterium tuberculosis
9 Citations (Scopus)

Discovery and optimisation studies of antimalarial phenotypic hits

Mital, A., Murugesan, D., Kaiser, M., Yeates, C. & Gilbert, I. H., 20 Oct 2015, In : European Journal of Medicinal Chemistry. 103, p. 530-538 9 p.

Research output: Contribution to journalArticle

Plasmodium falciparum
33 Citations (Scopus)

Discovery and structure-activity relationships of pyrrolone antimalarials

Murugesan, D., Mital, A., Kaiser, M., Shackleford, D. M., Morizzi, J., Katneni, K., Campbell, M., Hudson, A., Charman, S. A., Yeates, C. & Gilbert, I. H., 2013, In : Journal of Medicinal Chemistry. 56, 7, p. 2975-2990 16 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Structure-Activity Relationship Studies of Pyrrolone Antimalarial Agents

Murugesan, D., Kaiser, M., White, K. L., Norval, S., Riley, J., Wyatt, P. G., Charman, S. A., Read, K. D., Yeates, C. & Gilbert, I. H., 2013, In : ChemMedChem.

Research output: Contribution to journalArticle

Structure-Activity Relationship