Steele, Douglas

Professor, Deputy Head of Division

  • 3181 Citations
  • 27 h-Index
1985 …2024
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Research Output 1985 2020

2020

Abnormal Reward Valuation and Event-Related Connectivity in Unmedicated Major Depressive Disorder

Rupprechter, S., Stankevicius, A., Huys, Q. J. M., Seriès, P. & Steele, D., 7 Jan 2020, In : Psychological Medicine. 9 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Reward
Gyrus Cinguli
Depression
Decision Making

Cognitive consequences of opioid use

Baldacchino, A., Steele, D., Davey, F. & Tolomeo, S., 2020, Cognition and Addiction: A Researcher's Guide from Mechanisms Towards Interventions. Verdejo-Garcia, A. (ed.). 1 ed. Academic Press, p. 179-198 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

2019
17 Downloads (Pure)

A Roadmap for Integrating Neuroscience into Addiction Treatment: A Consensus of the Neuroscience Interest Group of the International Society of Addiction Medicine

Verdejo-Garcia, A., Lorenzetti, V., Manning, V., Piercy, H., Bruno, R., Hester, R., Pennington, D., Tolomeo, S., Arunogiri, S., Bates, M. E., Bowden-Jones, H., Campanella, S., Daughters, S., Kouimtsidis, C., Lubman, D. I., Meyerhoff, D. J., Ralph, A., Rezapour, T., Tavakoli, H., Zare-Bidoky, M. & 6 others, Zilverstand, A., Steele, D., Moeller, S. J., Paulus, M. P., Baldacchino, A. & Ekhtiari, H., 23 Dec 2019, In : Frontiers in Psychiatry. 10, p. 1-23 23 p., 877.

Research output: Contribution to journalArticle

Open Access
File
Public Opinion
Neurosciences
Consensus
Medicine
Neuroimaging
6 Citations (Scopus)
39 Downloads (Pure)

Chronic tobacco smoking and neuropsychological impairments: A systematic review and meta-analysis

Conti, A. A., McLean, L., Tolomeo, S., Steele, J. D. & Baldacchino, A., Jan 2019, In : Neuroscience and Biobehavioral Reviews. 96, 1, p. 143-154 12 p.

Research output: Contribution to journalReview article

Open Access
File
Impulsive Behavior
Meta-Analysis
Smoking
Intelligence
Benchmarking

Comment on Maggi et al., "Cognitive correlates of prospective memory in dystonia"

Gilbertson, T. & Steele, J. D., 11 Nov 2019, In : Parkinsonism and Related Disorders. 68, p. 91 1 p.

Research output: Contribution to journalLetter

28 Downloads (Pure)

Effects of opioid dependence on visuospatial memory and its associations with depression and anxiety

Tolomeo, S., Davey, F., Steele, D. & Baldacchino, A., 23 Oct 2019, In : Frontiers in Psychiatry. 10, p. 1-8 8 p., 743.

Research output: Contribution to journalArticle

Open Access
File
Opioid Analgesics
Anxiety
Depression
Buprenorphine
Neuropsychological Tests
45 Downloads (Pure)

Impaired reward-related learning signals in remitted unmedicated patients with recurrent depression

Geugies, H., Mocking, R. J. T., Figueroa, C. A., Groot, P. F. C., Marsman, J-B. C., Servaas, M. N., Steele, D., Schene, A. H. & Ruhé, H. G., Aug 2019, In : Brain. 142, 8, p. 2510-2522 13 p.

Research output: Contribution to journalArticle

Open Access
File
Anhedonia
Reward
Ventral Tegmental Area
Learning
Depression
2 Citations (Scopus)
82 Downloads (Pure)

Maladaptive striatal plasticity and abnormal reward-learning in cervical dystonia

Gilbertson, T., Humphries, M. & Steele, D., 7 Apr 2019, In : European Journal of Neuroscience. 14 p.

Research output: Contribution to journalArticle

Open Access
File
Corpus Striatum
Torticollis
Reward
Learning
Long-Term Potentiation
46 Downloads (Pure)

Neural correlates of weighted reward prediction error during reinforcement learning classify response to cognitive behavioral therapy in depression

Queirazza, F., Fouragnan, E., Steele, D., Cavanagh, J. & Philiastides, M. G., 31 Jul 2019, In : Science Advances. 5, 7, p. 1-15 15 p., eaav4962.

Research output: Contribution to journalArticle

Open Access
File
reinforcement
learning
therapy
predictions
pretreatment

Neurocognitive consequences of chronic cannabis use: a systematic review and meta-analysis

Figueiredo, P. R., Tolomeo, S., Steele, D. & Baldacchino, A., 9 Nov 2019, In : Neuroscience and Biobehavioral Reviews. 108, p. 358-369 12 p.

Research output: Contribution to journalReview article

Cannabis
Meta-Analysis
Impulsive Behavior
Long-Term Memory
Health Services Needs and Demand
2 Citations (Scopus)
45 Downloads (Pure)

Pragmatic Neuroscience for Clinical Psychiatry

Steele, D. & Paulus, M. P., 1 Jul 2019, In : British Journal of Psychiatry. 215, 1, p. 404-408 5 p.

Research output: Contribution to journalArticle

Open Access
File
Neurosciences
Psychiatry
National Institute of General Medical Sciences (U.S.)
Methamphetamine
Organized Financing
2 Citations (Scopus)
125 Downloads (Pure)

The Neurobiology of Personal Control During Reward Learning and Its Relationship to Mood

Romaniuk, L., Sandu, A-L., Waiter, G. D., McNeil, C. J., Xueyi, S., Harris, M. A., MacFarlane, J. A., Lawrie, S. M., Deary, I. J., Murray, A. D., Delgado, M. R., Steele, J. D., McIntosh, A. M. & Whalley, H. C., 9 Feb 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 2, p. 190-199 10 p.

Research output: Contribution to journalArticle

Open Access
File
Neurobiology
Reward
Learning
Depression
Anhedonia
2018
3 Citations (Scopus)
132 Downloads (Pure)

Assessing ADHD symptoms in children and adults: Evaluating the role of objective measures

Emser, T. S., Johnston, B., Steele, J., Kooij, S., Thorell, L. & Christiansen, H., 18 May 2018, In : Behavioral and Brain Functions. 14, p. 1-14 14 p., 11.

Research output: Contribution to journalArticle

Open Access
File
Guidelines
Interviews
Support Vector Machine
5 Citations (Scopus)
149 Downloads (Pure)

Compulsivity in opioid dependence

Tolomeo, S., Matthews, K., Steele, J. D. & Baldacchino, A., 2 Feb 2018, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 81, p. 333-339 7 p.

Research output: Contribution to journalArticle

Open Access
File
Opioid Analgesics
Impulsive Behavior
Heroin
Magnetic Resonance Imaging
Septal Nuclei
4 Citations (Scopus)
101 Downloads (Pure)

Major Depression Impairs the Use of Reward Values for Decision-Making

Rupprechter, S., Stankevicius, A., Huys, Q. J. M., Steele, J. & Seriès, P., 14 Sep 2018, In : Scientific Reports. 8, 1, 8 p., 13798.

Research output: Contribution to journalArticle

Open Access
File
Reward
Decision Making
Depression
Fractals
Aptitude
2017
11 Citations (Scopus)
272 Downloads (Pure)

Comprehensive review: Computational modelling of Schizophrenia

Valton, V., Romaniuk, L., Steele, D., Lawrie, S. & Series, P., Dec 2017, In : Neuroscience and Biobehavioral Reviews. 83, p. 631-646 16 p.

Research output: Contribution to journalReview article

Open Access
File
Schizophrenia
Psychopathology
gamma-Aminobutyric Acid
Glutamic Acid
Dopamine
2 Citations (Scopus)
129 Downloads (Pure)

Conditioned task-set competition: Neural mechanisms of emotional interference in depression

Stolicyn, A., Steele, J. D. & Seriès, P., Apr 2017, In : Cognitive, Affective, and Behavioral Neuroscience. 17, 2, p. 269-289 21 p.

Research output: Contribution to journalArticle

Open Access
File
Stroop Test
Depression
Amygdala
Reaction Time
Synaptic Transmission
22 Citations (Scopus)
94 Downloads (Pure)

Increased neural response to social rejection in major depression

Kumara, P., Waiter, G. D., Dubois, M., Milders, M., Reid, I. & Steele, J. D., 7 Nov 2017, In : Depression and Anxiety. 34, 11, p. 1049-1056 8 p.

Research output: Contribution to journalArticle

Open Access
File
Social Distance
Major Depressive Disorder
Depression
Social Isolation
Pleasure
12 Citations (Scopus)
121 Downloads (Pure)

Modeling trait anxiety: from computational processes to personality

Raymond, J. G., Steele, J. D. & Seriès, P., 23 Jan 2017, In : Frontiers in Psychiatry. 8, p. 1-19 19 p., 1.

Research output: Contribution to journalReview article

Open Access
File
Anxiety Disorders
Psychiatry
Personality
Anxiety
Mood Disorders
3 Citations (Scopus)
106 Downloads (Pure)

Schizophrenia illness severity is associated with reduced loss aversion

Currie, J., Buruju, D., Perrin, J. S., Reid, I. C., Steele, J. D. & Feltovich, N., Jun 2017, In : Brain Research. 1664, p. 9-16 8 p.

Research output: Contribution to journalArticle

Open Access
File
Schizophrenia
Decision Making
Regression Analysis
Control Groups
Research
2016
20 Citations (Scopus)
128 Downloads (Pure)

A causal role for the anterior mid-cingulate cortex in negative affect and cognitive control

Tolomeo, S., Christmas, D., Jentzsch, I., Johnston, B., Sprengelmeyer, R., Matthews, K. & Steele, J. D., 1 Jun 2016, In : Brain. 139, 6, p. 1844-1854 11 p.

Research output: Contribution to journalArticle

Open Access
File
Gyrus Cinguli
Facial Expression
Treatment-Resistant Depressive Disorder
Pain
Stroop Test
14 Citations (Scopus)
114 Downloads (Pure)

Multifaceted impairments in impulsivity and brain structural abnormalities in opioid dependence and abstinence

Tolomeo, S., Gray, S., Matthews, K., Steele, J. D. & Baldacchino, A., Oct 2016, In : Psychological Medicine. 46, 13, p. 2841-2853 13 p.

Research output: Contribution to journalArticle

Open Access
File
Impulsive Behavior
Methadone
Opioid Analgesics
Brain
Gambling
120 Downloads (Pure)

Neural correlates of fears of abandonment and rejection in borderline personality disorder

Romaniuk, L., Pope, M., Nicol, K., Steele, J. & Hall, J., 29 Dec 2016, In : Wellcome Open Research. 1, 33, p. 1-11 11 p.

Research output: Contribution to journalArticle

File
Borderline Personality Disorder
Fear
Chemical activation
Reinforcement learning
Mesencephalon
11 Citations (Scopus)
159 Downloads (Pure)

Neural correlates of social exchanges during the Prisoner’s Dilemma game in depression

Gradin, V. B., Pérez, A., Macfarlane, J. A., Cavin, I., Waiter, G., Tone, E. B., Dritschel, B., Maiche, A. & Steele, J. D., Apr 2016, In : Psychological Medicine. 46, 6, p. 1289-1300 12 p.

Research output: Contribution to journalArticle

Open Access
File
Emotions
Behavioral Economics
Prefrontal Cortex
Depression
Guilt
2015
23 Citations (Scopus)

Abnormal brain responses to social fairness in depression: an fMRI study using the Ultimatum Game

Gradin, V. B., Pérez, A., MacFarlane, J. A., Cavin, I., Waiter, G., Engelmann, J., Dritschel, B., Pomi, A., Matthews, K. & Steele, J. D., Apr 2015, In : Psychological Medicine. 45, 6, p. 1241-1251 11 p.

Research output: Contribution to journalArticle

Nucleus Accumbens
Behavioral Economics
Magnetic Resonance Imaging
Depression
Automatic Data Processing
17 Citations (Scopus)
135 Downloads (Pure)

Failure of hippocampal deactivation during loss events in treatment-resistant depression

Johnston, B. A., Tolomeo, S., Gradin, V., Christmas, D., Matthews, K. & Steele, J. D., Sep 2015, In : Brain. 138, 9, p. 2766-2776 11 p.

Research output: Contribution to journalArticle

Open Access
File
Treatment-Resistant Depressive Disorder
Major Depressive Disorder
Raphe Nuclei
Hippocampus
Periaqueductal Gray
23 Citations (Scopus)

Predicting methylphenidate response in attention deficit hyperactivity disorder: a preliminary study

Johnston, B. A., Coghill, D., Matthews, K. & Steele, J. D., Jan 2015, In : Journal of Psychopharmacology. 29, 1, p. 24-30 7 p.

Research output: Contribution to journalArticle

Methylphenidate
Attention Deficit Disorder with Hyperactivity
Conduct Disorder
Intelligence
Multivariate Analysis
18 Citations (Scopus)

Structural MRI-based predictions in patients with treatment-refractory depression (TRD)

Johnston, B. A., Steele, J. D., Tolomeo, S., Christmas, D. & Matthews, K., 17 Jul 2015, In : PLoS ONE. 10, 7, 16 p., 0132958.

Research output: Contribution to journalArticle

2014
23 Citations (Scopus)

Abnormal Brain Activity During a Reward and Loss Task in Opiate Dependent Patients Receiving Methadone Maintenance Therapy

Gradin, V. B., Baldacchino, A., Balfour, D., Matthews, K. & Steele, J. D., Mar 2014, In : Neuropsychopharmacology. 39, 4, p. 885-894 10 p.

Research output: Contribution to journalArticle

Opiate Alkaloids
Methadone
Reward
Brain
Therapeutics
42 Citations (Scopus)

Brainstem abnormalities in attention deficit hyperactivity disorder support high accuracy individual diagnostic classification

Johnston, B. A., Mwangi, B., Matthews, K., Coghill, D., Konrad, K. & Steele, J. D., Oct 2014, In : Human Brain Mapping. 35, 10, p. 5179-5189 11 p.

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Brain Stem
Psychiatry
Brain
Biomarkers
47 Citations (Scopus)
102 Downloads (Pure)

Nonlinear complexity analysis of brain fMRI signals in schizophrenia

Sokunbi, M. O., Gradin, V. B., Waiter, G. D., Cameron, G. G., Ahearn, T. S., Murray, A. D., Steele, D. J. & Staff, R. T., 13 May 2014, In : PLoS ONE. 9, 5

Research output: Contribution to journalArticle

Open Access
File
Systems Analysis
Brain
Schizophrenia
Entropy
Magnetic Resonance Imaging
2013
26 Citations (Scopus)
90 Downloads (Pure)

Imaging conditioned fear circuitry using awake rodent fMRI

Brydges, N. M., Whalley, H. C., Jansen, M. A., Merrifield, G. D., Wood, E. R., Lawrie, S. M., Wynne, S-M., Day, M., Fleetwood-Walker, S., Steele, D., Marshall, I., Hall, J. & Holmes, M. C., 22 Jan 2013, In : PLoS ONE. 9, 1, p. 1-7 7 p., e54197.

Research output: Contribution to journalArticle

Open Access
File
fearfulness
magnetic resonance imaging
Fear
Rodentia
rodents
44 Citations (Scopus)

Salience network-midbrain dysconnectivity and blunted reward signals in schizophrenia

Gradin, V. B., Waiter, G., O'Connor, A., Romaniuk, L., Stickle, C., Matthews, K., Hall, J. & Steele, J. D., 28 Feb 2013, In : Psychiatry Research: Neuroimaging. 211, 2, p. 104-111 8 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Vagus nerve stimulation for chronic major depressive disorder: 12-month outcomes in highly treatment-refractory patients

Christmas, D., Steele, J. D., Tolomeo, S., Eljamel, M. S. & Matthews, K., 25 Sep 2013, In : Journal of Affective Disorders. 150, 3, p. 1221-1225

Research output: Contribution to journalArticle

Vagus Nerve Stimulation
Major Depressive Disorder
Treatment-Resistant Depressive Disorder
Neurosurgery
Therapeutics
2012
19 Citations (Scopus)

Abnormal neural responses to social exclusion in schizophrenia

Gradin, V. B., Waiter, G., Kumar, P., Stickle, C., Milders, M., Matthews, K., Reid, I., Hall, J. & Steele, J. D., 16 Aug 2012, In : PLoS ONE. 7, 8, p. - 7 p., e42608.

Research output: Contribution to journalArticle

123 Citations (Scopus)

Electroconvulsive therapy reduces frontal cortical connectivity in severe depressive disorder

Perrin, J. S., Merz, S., Bennett, D. M., Currie, J., Steele, D. J., Reid, I. C. & Schwarzbauer, C., 3 Apr 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 14, p. 5464-5468 5 p.

Research output: Contribution to journalArticle

108 Citations (Scopus)

Multi-centre diagnostic classification of individual structural neuroimaging scans from patients with major depressive disorder

Mwangi, B., Ebmeier, K. P., Matthews, K. & Steele, J. D., May 2012, In : Brain. 135, 5, p. 1508-1521 14 p.

Research output: Contribution to journalArticle

Neural responses to rewards and punishments in patients with opiate dependence on methadone treatment: fNEMO study

Gradin, V., Gray, S., MacFarlane, J., Waiter, G., Balfour, D., Matthews, K., Baldacchino, A. & Steele, D., Oct 2012, In : European Neuropsychopharmacology. 22, Suppl 2, p. S402-S403 2 p., P.6.c.008.

Research output: Contribution to journalMeeting abstract

39 Citations (Scopus)
20 Citations (Scopus)

Predictive classification of individual magnetic resonance imaging scans from children and adolescents

Johnston, B. A., Mwangi, B., Matthews, K., Coghill, D. & Steele, J. D., Dec 2012, In : European Child & Adolescent Psychiatry. 22, 12, p. 733-744 12 p.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Adolescent Psychiatry
Child Psychiatry
Neuroimaging
Psychiatry
2011

Abnormal medial prefrontal cortex responses to social exclusion in schizophrenia: an FMRI study

Gradin, V., Waiter, G., Kumar, P., Ahearn, T., Stickle, C., Milders, M., Matthews, K., Reid, I., Hall, J. & Steele, J. D., Sep 2011, In : European Neuropsychopharmacology. 21, p. S305-S305 1 p., P.1.e.004.

Research output: Contribution to journalBook/Film/Article review

A MRI investigation of electroconvulsive therapy (ECT) for the treatment of depression

Perrin, J. S., Bennett, D. M., Currie, J., Steele, J. D. & Reid, I. C., Aug 2011, In : Journal of Psychopharmacology. 25, 8, p. A54-A54 1 p.

Research output: Contribution to journalBook/Film/Article review

2 Citations (Scopus)

Decision-making in schizophrenia studied within an economics game paradigm

Currie, J., Buruju, D., Perrin, J., Feltovich, N., Reid, I. C. & Steele, J. D., 2011, In : Journal of Psychopharmacology. 25, 8, p. A71 1 p., TD24.

Research output: Contribution to journalBook/Film/Article review

216 Citations (Scopus)

Expected value and prediction error abnormalities in depression and schizophrenia

Gradin, V. B., Kumar, P., Waiter, G., Ahearn, T., Stickle, C., Milders, M., Reid, I., Hall, J. & Steele, J. D., 2011, In : Brain. 134, 6, p. 1751-1764 14 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Long term outcome of thermal anterior capsulotomy for chronic, treatment refractory depression

Christmas, D., Eljamel, M. S., Butler, S., Hazari, H., MacVicar, R., Steele, J. D., Livingstone, A. & Matthews, K., Jun 2011, In : Journal of Neurology, Neurosurgery and Psychiatry. 82, 6, p. 594-600 7 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

The insular cortex and the neuroanatomy of major depression

Sprengelmeyer, R., Steele, J. D., Mwangi, B., Kumar, P., Christmas, D., Milders, M. & Matthews, K., Sep 2011, In : Journal of Affective Disorders. 133, 1-2, p. 120-127 8 p.

Research output: Contribution to journalArticle

2010

Abnormalities in reward prediction error signals in depression and schizophrenia

Gradin, V., Kumar, P., Waiter, G., Ahearn, T., Reid, I., Stickle, C., Milders, M., Hall, J. & Steele, J. D., Aug 2010, In : European Neuropsychopharmacology. 20, s3, p. S173-S173 1 p.

Research output: Contribution to journalBook/Film/Article review

Abnormalities in reward prediction error signals in depression and schizophrenia

Gradin, V. B., Kumar, P., Waiter, G., Ahearn, T., Reid, I., Stickle, C., Milders, M., Hall, J. & Steele, J. D., Mar 2010, In : European Neuropsychopharmacology. 20, s1, p. S67-S68 2 p.

Research output: Contribution to journalBook/Film/Article review

17 Citations (Scopus)

Between- and within-scanner variability in the CaliBrain study n-back cognitive task

Gradin, V., Gountouna, V-E., Waiter, G., Ahearn, T. S., Brennan, D., Condon, B., Marshall, I., McGonigle, D. J., Murray, A. D., Whalley, H., Cavanagh, J., Hadley, D., Lymer, K., McIntosh, A., Moorhead, T. W., Job, D., Wardlaw, J., Lawrie, S. M. & Steele, J. D., 30 Nov 2010, In : Psychiatry Research: Neuroimaging. 184, 2, p. 86-95 10 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)

Functional Magnetic Resonance Imaging (fMRI) reproducibility and variance components across visits and scanning sites with a finger tapping task

Gountouna, V-E., Job, D. E., McIntosh, A. M., Moorhead, T. W. J., Lymer, G. K. L., Whalley, H. C., Hall, J., Waiter, G. D., Brennan, D., McGonigle, D. J., Ahearn, T. S., Cavanagh, J., Condon, B., Hadley, D. M., Marshall, I., Murray, A. D., Steele, J. D., Wardlaw, J. M. & Lawrie, S. M., 1 Jan 2010, In : NeuroImage. 49, 1, p. 552-560 9 p.

Research output: Contribution to journalArticle