Allen, Edwin

Dr

  • Head of the Cell Culture Facility, MRC PPU
  • 72 Citations
  • 3 h-Index
20132016
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Fingerprint Dive into the research topics where Edwin Allen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 8 Similar Profiles
Juvenile Epithelial of Meesmann Corneal Dystrophy Medicine & Life Sciences
Keratin-12 Medicine & Life Sciences
Clustered Regularly Interspaced Short Palindromic Repeats Medicine & Life Sciences
Guide RNA Medicine & Life Sciences
Missense Mutation Medicine & Life Sciences
Unfolded Protein Response Medicine & Life Sciences
DNA Cleavage Medicine & Life Sciences
Mutation Medicine & Life Sciences

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Research Output 2013 2016

  • 72 Citations
  • 3 h-Index
  • 3 Article
45 Citations (Scopus)
112 Downloads (Pure)

CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting

Courtney, D. G., Moore, J. E., Atkinson, S. D., Maurizi, E., Allen, E. H. A., Leslie Pedrioli, D. M. L., Mclean, W. H. I., Nesbit, M. A. & Moore, C. B. T., 2016, In : Gene Therapy. 23, 1, p. 108-112

Research output: Contribution to journalArticle

Open Access
File
Clustered Regularly Interspaced Short Palindromic Repeats
Guide RNA
DNA Cleavage
Single Nucleotide Polymorphism
Mutation
4 Citations (Scopus)
115 Downloads (Pure)

Keratin 12 missense mutation induces the unfolded protein response and apoptosis in meesmann epithelial corneal dystrophy

Allen, E. H. A., Courtney, D. G., Atkinson, S. D., Moore, J. E., Mairs, L., Poulsen, E. T., Schiroli, D., Maurizi, E., Cole, C., Hickerson, R. P., James, J., Murgatroyd, H., Smith, F. J. D., MacEwen, C., Enghild, J. J., Nesbit, M. A., Leslie Pedrioli, D. M., McLean, W. H. I. & Moore, C. B. T., 15 Mar 2016, In : Human Molecular Genetics. 25, 6, p. 1176-1191 16 p., ddw001.

Research output: Contribution to journalArticle

Open Access
File
Juvenile Epithelial of Meesmann Corneal Dystrophy
Keratin-12
Unfolded Protein Response
Missense Mutation
Apoptosis
23 Citations (Scopus)

Allele-specific siRNA silencing for the common keratin 12 founder mutation in Meesmann epithelial corneal dystrophy

Allen, E. H. A., Atkinson, S. D., Liao, H., Moore, J. E., Pedrioli, D. M. L., Smith, F. J. D., McLean, W. H. I. & Moore, C. B. T., 2013, In : Investigative Ophthalmology & Visual Science. 54, 1, p. 494-502 9 p.

Research output: Contribution to journalArticle