Projects per year
Personal profile
Biography
Ewan Pearson is Professor of Diabetic Medicine at the University of Dundee, Adjunct Professor at the University of Lund, Visiting Professor at the University of Edinburgh, and Honorary Consultant in Diabetes and Endocrinology at Ninewells Hospital and Medical School in Dundee. Ewan is an Associate Director for the BHF Data Science Centre, where he leads the Diabetes Data Catalyst.
Ewan obtained his medical degree from the University of Cambridge School of Clinical Medicine, UK. He undertook a Wellcome Trust Clinical Training fellowship with Prof Andrew Hattersley at the University of Exeter Medical School, UK and completed his PhD in the physiology and treatment of monogenic diabetes. He then moved to Dundee where he was supported by a Chief Scientist Office Clinician Scientist fellowship and then by a Wellcome Trust Investigator Award. Over the last ten years in Dundee his research interests have been in the phenotypic and genotypic determinants of drug response in diabetes, and in stratified approaches to the management of diabetes. He leads the IMI-DIRECT project on stratification in type 2 diabetes and is WP lead for the IMI-SOPHIA project on obesity outcomes. Ewan also leads the recently awarded £2.8M iDiabetes programme - to implement precision diabetes care in Tayside. Ewan is co-chair of the Wellcome Early Career Awards Committee.
Ewan has been awarded the Royal College of Physicians of Edinburgh Croom Lecture, an EASD Rising Star award, the Diabetes UK RD Lawrence Lecture, the EASD Minkowski Award, and the Diabetes UK Dorothy Hodgkin Lecture for his work in these areas. In 2022 Ewan was elected as a Fellow of the Royal Society of Edinburgh.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Medicine, The physiology and treatment of monogenic diabetes, Peninsula Medical School
Award Date: 1 Jan 2005
Master of Arts, University of Cambridge
Award Date: 1 Jan 1997
Bachelor of Medicine, University of Cambridge
Award Date: 1 Jan 1995
Bachelor of Arts, Part 1a & 1b Medical Science. Part 2 Neuroscience, University of Cambridge
Award Date: 1 Jan 1993
External positions
Guest Professor, Lund University
1 Feb 2021 → …
Visiting Professor, University of Chinese Academy of Sciences
Visiting Professor, University of Edinburgh
Fingerprint
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Network
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The iDiabetes Platform - Enhanced Phenotyping of Patients With Diabetes For Precision Diagnosis, Prognosis and Treatment (Joint with NHS Education for Scotland and University of Aberdeen)
Bell, S., Croudace, T., Cunningham, S., Dillon, J., Doney, A., Donnan, P., Farre, A., Lang, C., McCrimmon, R., Mordi, I., Palmer, C. & Pearson, E.
1/05/22 → 30/04/26
Project: Research
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PRecision Medicine for Diabetis Individuals: a Joint Malaysia-UK Effort (PRIME) - (Joint with UMBI)
Doney, A., Lang, C., Mordi, I., Palmer, C., Pearson, E. & Trucco, M.
31/12/19 → 1/04/23
Project: Research
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Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes
Zhou, K., Bellenguez, C., Spencer, C. C. A., Bennett, A. J., Coleman, R. L., Tavendale, R., Hawley, S. A., Donnelly, L. A., Schofield, C., Groves, C. J., Burch, L., Carr, F., Strange, A., Freeman, C., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Craddock, N., & 31 others , Feb 2011, In: Nature Genetics. 43, 2, p. 117-120 4 p.Research output: Contribution to journal › Letter › peer-review
341 Citations (Scopus) -
A phenome-wide comparative analysis of genetic discordance between obesity and type 2 diabetes
Coral, D. E., Fernandez-Tajes, J., Tsereteli, N., Pomares-Millan, H., Fitipaldi, H., Mutie, P. M., Atabaki-Pasdar, N., Kalamajski, S., Poveda, A., Miller-Fleming, T. W., Zhong, X., Giordano, G. N., Pearson, E. R., Cox, N. J. & Franks, P. W., 26 Jan 2023, (E-pub ahead of print) In: Nature Metabolism. 16 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models
IMI DIRECT Consortium, Rasmussen, S. & Brunak, S., 2 Jan 2023, (E-pub ahead of print) In: Nature Biotechnology. 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Pharmacogenomics of GLP-1 Receptor Agonists: a genome-wide analysis of observational data and large randomised controlled trials
Dawed, A. Y., Mari, A., Brown, A., McDonald, T. J., Li, L., Wang, S., Hong, M-G., Sharma, S., Robertson, N. R., Mahajan, A., Wang, X., Walker, M., Gough, S., 't Hart, L. M., Zhou, K., Forgie, I., Ruetten, H., Pavo, I., Bhatnagar, P., Jones, A. G., & 1 others , 1 Jan 2023, In: The Lancet Diabetes and Endocrinology. 11, 1, p. 33-41 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)11 Downloads (Pure) -
Weight variability and cardiovascular outcomes: a systematic review and meta-analysis
Massey, R. J., Siddiqui, M. K., Pearson, E. R. & Dawed, A. Y., 2023, In: Cardiovascular Diabetology. 22, 12 p., 5.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure)
Datasets
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Type 2 Diabetes, Metabolic Traits, and Risk of Heart Failure: A Mendelian Randomization Study
Mordi, I. (Creator), Lumbers, R. T. (Creator), Palmer, C. (Creator), Pearson, E. (Creator), Sattar, N. (Creator), Holmes, M. V. (Creator) & Lang, C. (Creator), figshare, 6 Apr 2021
DOI: 10.2337/figshare.14448480
Dataset
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Combined GWAS of metaformin glycaemic reponse in 1372 GoDARTS patients
Zhou, K. (Creator), Pearson, E. (Contributor) & Palmer, C. (Contributor), University of Dundee, 7 Oct 2016
DOI: 10.15132/10000119, https://www.ebi.ac.uk/ega/datasets/EGAD00001002277
Dataset
File
Prizes
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Diabetes UK/Servier Type 2 Diabetes Research Award for outstanding contribution to the advancement and understanding of Type 2 Diabetes and its treatment
Pearson, Ewan R. (Recipient), 2007
Prize: Prize (including medals and awards)
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Diabetes UK/Servier Type 2 Diabetes Research Award for outstanding contribution to the advancement of the understanding of Type 2 Diabetes and its treatment
Pearson, Ewan R. (Recipient), 2003
Prize: Prize (including medals and awards)
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Diabetes UK/Servier Type 2 Diabetes Research Award for outstanding contribution to the advancement of the understanding of Type 2 Diabetes and its treatment.
Pearson, Ewan R. (Recipient), 2006
Prize: Prize (including medals and awards)
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Dorothy Hodgkin Lecture 2020/2021
Pearson, Ewan (Recipient), Mar 2020
Prize: Prize (including medals and awards)
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EASD Minkowski Award 2017, Lisbon
Pearson, Ewan (Recipient), 2017
Prize: Prize (including medals and awards)
Activities
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European Diabetology (External organisation)
Ewan Pearson (Trustee)
1 Sep 2021 → 1 Sep 2024Activity: Membership types › Membership of board
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Wellcome Trust (External organisation)
Ewan Pearson (Chair)
1 Jan 2020 → 1 Dec 2021Activity: Membership types › Membership of panel
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American Diabetes Association (External organisation)
Ewan Pearson (Chair)
1 Jan 2019 → 1 Jan 2023Activity: Membership types › Membership of group
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Discovery Days 2014
Jonathan Urch (Organiser), Pete Downes (Chair), Karl Leydecker (Presenter), Graeme Hutton (Presenter), Charlotte Proby (Presenter), Amin Abdolvand (Presenter), Doreen Cantrell (Chair), John Rowan (Presenter), Bruce Burton (Presenter), David Horn (Presenter), John Connell (Chair), Ewan Pearson (Presenter), Ruth O'Riordan (Presenter), Graeme Morton (Presenter), Anna Campbell (Presenter), John Baldacchino (Presenter), Karim Labib (Presenter), Stephen Decent (Chair), Fraser Smith (Presenter), Ioannis Anastasopoulos (Presenter), Deborah Peel (Presenter), Christopher Whatley (Chair), Ioan Fazey (Presenter), Graham Chadwick (Presenter), James Livesey (Presenter), Mark Robson (Presenter), Rory McCrimmon (Presenter) & Christopher Connolly (Presenter)
9 Jan 2014 → 10 Jan 2014Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
File
Press / Media
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DNA variant affects diabetes risk and treatment response
Ewan R. Pearson, Colin Neil Alexander Palmer & Louise A. Donnelly
1/05/13
1 item of Media coverage
Press/Media: Research