Projects per year
Personal profile
Biography
Ewan Pearson is Professor of Diabetic Medicine at the University of Dundee, Visiting Professor at the University of Edinburgh, and Honorary Consultant in Diabetes and Endocrinology at Ninewells Hospital and Medical School in Dundee. In the School of Medicine, he is the Head of Division, Population Health & Genomics, and the Director of the Dundee Clinical Academic Track.
Professor Pearson obtained his medical degree from the University of Cambridge School of Clinical Medicine, UK. He undertook a Wellcome Trust Clinical Training fellowship with Prof Andrew Hattersley at the University of Exeter Medical School, UK and completed his PhD in the physiology and treatment of monogenic diabetes. He then moved to Dundee where he was supported by a Chief Scientist Office Clinician Scientisit fellowship and, more recently, by a Wellcome Trust Investigator Award. Over the last ten years in Dundee his research interests have been in the phenotypic and genotypic determinants of drug response in diabetes, and in stratified approaches to the management of diabetes. He leads the IMI-DIRECT project on stratification in type 2 diabetes and is strand 2 lead on the ABPI-MRC funded MASTERMIND project. Ewan has been awarded the Royal College of Physicians of Edinburgh Croom Lecture, an EASD Rising Star award, the Diabetes UK RD Lawrence Lecture and the EASD Minkowski Award for his work in these areas.
Education/Academic qualification
Doctor of Medicine, Peninsula Medical School
Master of Arts, University of Cambridge
Bachelor of Medicine, University of Cambridge
Bachelor of Arts, University of Cambridge
External positions
Visiting Professor, University of Edinburgh
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Projects 2013 2024
Integration of Knowledge and Biobank Resources in Comprehensive Translational Approach for Personalized Prevention and Treatment of Metabolic Disorders (INTEGROMED) (joint with Latvian Biomedical Research and Study Centre (Lead), Lund University and Weizmann Institute of Science Ltd)
Brown, A., Brown, A., Jefferson, E., Palmer, C. & Pearson, E.
COMMISSION OF THE EUROPEAN COMMUNITIES
1/10/19 → 30/09/22
Project: Research
Hyperglycemia/Tight Junction Dysfunction Validation A (Weizman Inst. lead)
1/08/19 → 31/07/20
Project: Research
CARdiomyopathy in type 2 DIAbetes mellitus (CARDIATEAM) (Joint with the INSERM as lead, CIBER- Network Centre for Biomedical Research, Luxembourg Institute of Health and 17 others)
Doney, A., Houston, G., Lang, C., Mordi, I., Palmer, C., Pearson, E. & Trucco, M.
COMMISSION OF THE EUROPEAN COMMUNITIES
1/03/19 → 29/02/24
Project: Research
Scotland India Diabetes Health Informatics Unit (joint with Madras Diabetes Research Foundation)
Doney, A., McCrimmon, R., Palmer, C., Pearson, E. & Trucco, M.
1/06/17 → 31/03/21
Project: Research
Research Output 1999 2019
4th ESPT Conference: pharmacogenomics and personalized medicine - research progress and clinical implementation
Sipeky, C., Llerena, A., Manolopoulos, V. G., Pearson, E., Mlakar, V., Gozzo, L., Simmaco, M., Marchetti, P., Re, M. D., Stankovic, S., Meyer, U., Cascorbi, I., Ingelman-Sundberg, M., Suarez-Kurtz, G., Marc, J., Katsila, T., Paulmichl, M., Nofziger, C., Ansari, M., Drago, F. & 1 others, , Oct 2019, In : Pharmacogenomics. 20, 15, p. 1063-1069 7 p.Research output: Contribution to journal › Article
A Type 1 Diabetes Genetic Risk Score Can Identify Patients With GAD65 Autoantibody-Positive Type 2 Diabetes Who Rapidly Progress to Insulin Therapy
Grubb, A. L., McDonald, T. J., Rutters, F., Donnelly, L., Hattersley, A. T., Oram, R. A., Palmer, C., van der Heijden, A. A., Carr, F., Elders, P. J. M., Weedon, M., Slieker, R. C., 't Hart, L. M., Pearson, E., Shields, B. M. & Jones, A. G., 1 Feb 2019, In : Diabetes Care. 42, 2, p. 208-214 7 p.Research output: Contribution to journal › Article
Development and validation of multivariable clinical diagnostic models to identify type 1 diabetes requiring rapid insulin therapy in adults aged 18-50 years
Lynam, A., McDonald, T., Hill, A., Dennis, J., Oram, R., Pearson, E., Weedon, M., Hattersley, A., Owen, K., Shields, B. & Jones, A., 26 Sep 2019, In : BMJ Open. 9, 9, p. 1-10 10 p., e031586.Research output: Contribution to journal › Article
Diabetes: Is there a future for Pharmacogenomics guided treatment?
Pearson, E., Aug 2019, In : Clinical Pharmacology & Therapeutics. 106, 2, p. 329-337 9 p.Research output: Contribution to journal › Article
Differential Association of Genetic Risk of Coronary Artery Disease with Development of Heart Failure with Reduced Versus Preserved Ejection Fraction: A GoDARTS Mendelian Randomization Study and Meta-Analysis
Mordi, I. R., Pearson, E. R., Palmer, C. N. A., Doney, A. S. F. & Lang, C. C., 12 Feb 2019, In : Circulation. 139, 7, p. 986-988 3 p.Research output: Contribution to journal › Letter
Datasets
Combined GWAS of metaformin glycaemic reponse in 1372 GoDARTS patients
Zhou, K. (Creator), University of Dundee, 7 Oct 2016
DOI: 10.15132/10000119, https://www.ebi.ac.uk/ega/datasets/EGAD00001002277
Dataset
Prizes
Diabetes UK/Servier Type 2 Diabetes Research Award for outstanding contribution to the advancement and understanding of Type 2 Diabetes and its treatment
Ewan R. Pearson (Recipient), 2007
Prize: Prize (including medals and awards)
Diabetes UK/Servier Type 2 Diabetes Research Award for outstanding contribution to the advancement of the understanding of Type 2 Diabetes and its treatment
Ewan R. Pearson (Recipient), 2003
Prize: Prize (including medals and awards)
Diabetes UK/Servier Type 2 Diabetes Research Award for outstanding contribution to the advancement of the understanding of Type 2 Diabetes and its treatment.
Ewan R. Pearson (Recipient), 2006
Prize: Prize (including medals and awards)
EASD Minkowski Award 2017, Lisbon
Ewan Pearson (Recipient), 2017
Prize: Prize (including medals and awards)
EASD Rising Star award for clinical science
Ewan R. Pearson (Recipient), 2007
Prize: Prize (including medals and awards)
Activities 2006 2017
- 3 Invited talk
ESPT meeting Catania, Sicilly
Ewan Pearson (Speaker)Activity: Talk or presentation types › Invited talk
EASD Genetics Study Group, Leiden
Ewan Pearson (Speaker)Activity: Talk or presentation types › Invited talk
The Croom Lecture - Royal College of Physicians of Edinburgh
Ewan R. Pearson (Speaker)Activity: Talk or presentation types › Invited talk
Press / Media
DNA variant affects diabetes risk and treatment response
Ewan R. Pearson, Colin Neil Alexander Palmer & Louise A. Donnelly
1/05/13
1 item of Media coverage
Press/Media: Research
Thesis
Clinical and genetic determinants of diabetic retinopathy
Author: Liu, Y., 2014Supervisor: Palmer, C. (Supervisor) & Pearson, E. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
Genetic and non-genetic determinants of drug response in type 2 diabetes
Author: Dawed, A. Y., 2017Supervisor: Pearson, E. (Supervisor) & Zhou, K. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Medicine
Genetic Epidemiology Studies of aspects of Diabetic Complications
Author: Deshmukh, H., 2014Supervisor: Colhoun, H. (Supervisor) & Pearson, E. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
Pharmacological modulation of insulin resistance - benefits and harms
Author: Vella, S., 2013Supervisor: Petrie, J. (Supervisor), Lang, C. (Supervisor) & Pearson, E. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Medicine