Tonelli, Francesca

Dr

  • 460 Citations
  • 8 h-Index
20132019
If you made any changes in Pure these will be visible here soon.

Fingerprint Dive into the research topics where Francesca Tonelli is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 81 Similar Profiles
Phosphorylation Chemical Compounds
Phosphotransferases Medicine & Life Sciences
Parkinson Disease Medicine & Life Sciences
rab GTP-Binding Proteins Chemical Compounds
Leucine Medicine & Life Sciences
Cilia Medicine & Life Sciences
Proteins Chemical Compounds
Chemical activation Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2013 2019

  • 460 Citations
  • 8 h-Index
  • 10 Article
3 Citations (Scopus)
90 Downloads (Pure)

A chemical-genetics approach to study the role of atypical Protein Kinase C in Drosophila

Hannaford, M., Loyer, N., Tonelli, F., Zoltner, M. & Januschke, J., 29 Jan 2019, In : Development. 146, 2, p. 1-11 11 p., dev170589.

Research output: Contribution to journalArticle

Open Access
File
Drosophila
Phosphotransferases
Drosophila Proteins
Cell Polarity
Nuclear Envelope
3 Downloads (Pure)

PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins

Berndsen, K., Lis, P., Yeshaw, W. M., Wawro, P. S., Nirujogi, R., Wightman, M., Macartney, T., Dorward, M., Knebel, A., Tonelli, F., Pfeffer, S. R. & Alessi, D., 12 Nov 2019, In : eLife. 8, p. 1-37 37 p., e50416.

Research output: Contribution to journalArticle

Open Access
File
Phosphoric Monoester Hydrolases
Phosphorylation
Phosphoprotein Phosphatases
Parkinson Disease
rab GTP-Binding Proteins
11 Citations (Scopus)
83 Downloads (Pure)

A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain

Dhekne, H. S., Yanatori, I., Gomez, R. C., Tonelli, F., Diez, F., Schüle, B., Steger, M., Alessi, D. R. & Pfeffer, S. R., 6 Nov 2018, In : eLife. 7, p. 1-26 26 p., e40202.

Research output: Contribution to journalArticle

Open Access
File
Aptitude
Hedgehogs
Cilia
Neurons
Parkinson Disease
20 Citations (Scopus)
218 Downloads (Pure)

Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson’s disease kinase

Lis, P., Burel, S., Steger, M., Mann, M., Brown, F., Diez, F., Tonelli, F., Holton, J. L., Winglok Ho, P., Ho, S-L., Chou, M-Y., Polinski, N. K., Martinez, T. N., Davies, P. & Alessi, D. R., 2 Jan 2018, In : Biochemical Journal. 475, 1, p. 1-22 22 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Kinases
Parkinson Disease
Phosphotransferases
Antibodies
Proteins
21 Citations (Scopus)
80 Downloads (Pure)

The Parkinson's disease VPS35[D620N] mutation enhances LRRK2 mediated Rab protein phosphorylation in mouse and human

Mir, R., Tonelli, F., Lis, P., Macartney, T., Polinski, N. K., Martinez, T. N., Chou, M-Y., Howden, A., König, T., Hotzy, C., Milenkovic, I., Brücke, T., Zimprich, A., Sammler, E. & Alessi, D., 6 Jun 2018, In : Biochemical Journal. 475, 11, p. 1861-1883 19 p.

Research output: Contribution to journalArticle

Open Access
File
Phosphorylation
Parkinson Disease
Mutation
Proteins
Phosphotransferases