Tonelli, Francesca

Dr

  • 411 Citations
  • 7 h-Index
20132019
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Fingerprint Dive into the research topics where Francesca Tonelli is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 39 Similar Profiles
Phosphorylation Chemical Compounds
Phosphotransferases Medicine & Life Sciences
Parkinson Disease Medicine & Life Sciences
rab GTP-Binding Proteins Chemical Compounds
Cilia Medicine & Life Sciences
Leucine Medicine & Life Sciences
Chemical activation Chemical Compounds
Proteins Chemical Compounds

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Research Output 2013 2019

  • 411 Citations
  • 7 h-Index
  • 9 Article
1 Citation (Scopus)
54 Downloads (Pure)

A chemical-genetics approach to study the role of atypical Protein Kinase C in Drosophila

Hannaford, M., Loyer, N., Tonelli, F., Zoltner, M. & Januschke, J., 29 Jan 2019, In : Development. 146, 2, p. 1-11 11 p., dev170589.

Research output: Contribution to journalArticle

Open Access
File
Drosophila
Phosphotransferases
Drosophila Proteins
Cell Polarity
Nuclear Envelope
7 Citations (Scopus)
52 Downloads (Pure)

A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain

Dhekne, H. S., Yanatori, I., Gomez, R. C., Tonelli, F., Diez, F., Schüle, B., Steger, M., Alessi, D. R. & Pfeffer, S. R., 6 Nov 2018, In : eLife. 7, p. 1-26 26 p., e40202.

Research output: Contribution to journalArticle

Open Access
File
Aptitude
Hedgehogs
Cilia
Neurons
Parkinson Disease
17 Citations (Scopus)
185 Downloads (Pure)

Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson’s disease kinase

Lis, P., Burel, S., Steger, M., Mann, M., Brown, F., Diez, F., Tonelli, F., Holton, J. L., Winglok Ho, P., Ho, S-L., Chou, M-Y., Polinski, N. K., Martinez, T. N., Davies, P. & Alessi, D. R., 2 Jan 2018, In : Biochemical Journal. 475, 1, p. 1-22 22 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Kinases
Parkinson Disease
Phosphotransferases
Antibodies
Proteins
14 Citations (Scopus)
51 Downloads (Pure)

The Parkinson's disease VPS35[D620N] mutation enhances LRRK2 mediated Rab protein phosphorylation in mouse and human

Mir, R., Tonelli, F., Lis, P., Macartney, T., Polinski, N. K., Martinez, T. N., Chou, M-Y., Howden, A., König, T., Hotzy, C., Milenkovic, I., Brücke, T., Zimprich, A., Sammler, E. & Alessi, D., 6 Jun 2018, In : Biochemical Journal. 475, 11, p. 1861-1883 19 p.

Research output: Contribution to journalArticle

Open Access
File
Phosphorylation
Parkinson Disease
Mutation
Proteins
Phosphotransferases
32 Citations (Scopus)
94 Downloads (Pure)

Rab29 activation of the Parkinson's disease-associated LRRK2 kinase

Purlyte, E., Dhekne, H. S., Sarhan, A. R., Gomez, R., Lis, P., Wightman, M., Martinez, T. N., Tonelli, F., Pfeffer, S. R. & Alessi, D. R., 15 Dec 2017, In : EMBO Journal. 36, 24, p. 3549-3681 18 p., e201798099.

Research output: Contribution to journalArticle

Open Access
File
Phosphorylation
Parkinson Disease
Phosphotransferases
Chemical activation
Biomarkers