Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Frederick Simeons is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism
MacLeod, A. K., Coquelin, K.-S., Huertas, L., Simeons, F. R. C., Riley, J., Casado, P., Guijarro, L., Casanueva, R., Frame, L., Pinto, E. G., Ferguson, L., Duncan, C., Mutter, N., Shishikura, Y., Henderson, C. J., Cebrian, D., Wolf, C. R. & Read, K. D. (Lead / Corresponding author), 13 Feb 2024, In: Proceedings of the National Academy of Sciences. 121, 7, p. 1-12 12 p., 2315069121.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)110 Downloads (Pure) -
Rational Exploration of 2,4-Diaminopyrimidines as DHFR Inhibitors Active against Mycobacterium abscessus and Mycobacterium avium, Two Emerging Human Pathogens
Andrade Meirelles, M., Almeida, V. M., Sullivan, J. R., de Toledo, I., dos Reis, C. V., Cunha, M. R., Zigweid, R., Shim, A., Sankaran, B., Woodward, E. L., Seibold, S., Liu, L., Mian, M. R., Battaile, K. P., Riley, J., Duncan, C., Simeons, F. R. C., Ferguson, L., Joji, H. & Read, K. D. & 5 others, , 14 Nov 2024, In: Journal of Medicinal Chemistry. 67, 21, p. 19143-19164 22 p.Research output: Contribution to journal › Article › peer-review
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Author Correction: Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis (Nature, (2018), 560, 7717, (192-197), 10.1038/s41586-018-0356-z)
Wyllie, S., Thomas, M., Patterson, S., Crouch, S., De Rycker, M., Lowe, R., Gresham, S., Urbaniak, M. D., Otto, T. D., Stojanovski, L., Simeons, F. R. C., Manthri, S., MacLean, L. M., Zuccotto, F., Homeyer, N., Pflaumer, H., Boesche, M., Sastry, L., Connolly, P. & Albrecht, S. & 12 others, , 4 Jul 2023, In: Nature. 619, p. E48 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Development of a 2,4-diaminothiazole series for the treatment of human African trypanosomiasis highlights the importance of static-cidal screening of analogues
Cleghorn, L. A. T., Wall, R. J., Albrecht, S., MacGowan, S. A., Norval, S., De Rycker, M., Woodland, A., Spinks, D., Thompson, S., Patterson, S., Corpas Lopez, V., Dey, G., Collie, I. T., Hallyburton, I., Kime, R., Simeons, F. R. C., Stojanovski, L., Frearson, J. A., Wyatt, P. G. & Read, K. D. & 2 others, , 13 Jul 2023, In: Journal of Medicinal Chemistry. 66, 13, p. 8896–8916 21 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)84 Downloads (Pure) -
Structure Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors
Thomas, M. G., McGonagle, K., Rowland, P., Robinson, D. A., Dodd, P. G., Camino-Díaz, I., Campbell, L., Cantizani, J., Castañeda, P., Conn, D., Craggs, P. D., Edwards, D., Ferguson, L., Fosberry, A., Frame, L., Goswami, P., Hu, X., Korczynska, J., MacLean, L. & Martin, J. & 21 others, , 10 Aug 2023, In: Journal of Medicinal Chemistry. 66, 15, p. 10413-10431 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)111 Downloads (Pure)
Prizes
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Industry and Academic Collaboration Award
De Rycker, M. (Recipient), Gilbert, I. (Recipient), Read, K. (Recipient), Wyllie, S. (Recipient), Wyatt, P. (Recipient), Gray, D. (Recipient), Thomas, M. (Recipient), Brand, S. (Recipient), McGonagle, K. (Recipient), Dodd, P. (Recipient), Dunne, J. (Recipient), MacLean, L. (Recipient), Thomas, J. (Recipient), Manthri, S. (Recipient), Paterson, C. (Recipient), Stojanovski, L. (Recipient), Pinto, E. (Recipient), Ferguson, L. (Recipient), Simeons, F. (Recipient), Torrie, L. (Recipient), Robinson, D. (Recipient), Riley, J. (Recipient), Frame, L. (Recipient), Garcia Sanchez, M. (Recipient), Da Silva Pacheco, J. (Recipient), Miles, T. (Recipient), Fiandor, J. M. (Recipient), Martin, J. J. (Recipient), Marco, M. (Recipient), Gonzalez, S. (Recipient), Cantizani, J. (Recipient), Cotillo, I. (Recipient) & Manzano, M. P. (Recipient), 12 Apr 2023
Prize: Prize (including medals and awards)
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School of Life Sciences Awards - Brian Cox Prize for Excellence in Public Engagement with Research
Simeons, F. (Recipient), Floyd, A. (Recipient), Kidd, G. (Recipient), Muqit, M. (Recipient), Patrick, S. (Recipient), Kocaturk, N. (Recipient), Davies, P. (Recipient), Cabrita Gulyurtlu, S. (Recipient), Cleghorn, L. (Recipient), Tamaki, F. (Recipient), Davis, S. (Recipient), Hedges, L. (Recipient), Robinson, C. (Recipient), Naylor, C. (Recipient), Koovits, P. (Recipient), Connell, D. (Recipient), Aitken, J. (Recipient), Halford-Forbes, E. (Recipient), Hinde, S. (Recipient), Clark, L. (Recipient), Saarela, D. (Recipient), Agarwal, S. (Recipient), Shi, G. (Recipient), Carton, B. (Recipient), Elliott, M. (Recipient), Soave, S. (Recipient) & Mackintosh, A. (Recipient), 2024
Prize: Prize (including medals and awards)
Activities
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Bonding
Floyd, A. (Host), Fong, E. (Chair), Mackintosh, A. (Host), Fairlamb, A. (Chair), Aitken, J. (Member of programme committee), Farrell, S. (Participant), Thomas, M. (Participant), Tarver, G. (Participant), Postis, V. (Participant), McGinnis, C. (Participant), Read, K. (Participant), Seizova, S. (Participant), Cleghorn, L. (Participant), Baragana, B. (Participant), Pearson, L.-A. (Participant), Bellany, F. (Participant), Pinto, E. (Participant), Simeons, F. (Participant), Godoy Magalhaes, L. (Participant), Bayliss, T. (Participant), Akwensi, J. (Participant), De Sousa Paradela, L. (Participant), Wyllie, S. (Participant), Anderson, G. (Participant), Wu, S. (Participant) & Urbanowska, A. (Participant)
16 Feb 2023 → 8 Apr 2023Activity: Participating in or organising an event types › Festival/Exhibition
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Parasite Soup - Word Broth
Floyd, A. (Host), Fong, E. (Host), Fairlamb, A. (Presenter), Wyllie, S. (Presenter), Mackintosh, A. (Host), Mackenna, G. (Speaker), Simeons, F. (Participant), Nagar, R. (Participant) & Urch, J. (Participant)
6 Apr 2023Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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The Last Mill
Simpson, D. (Contributor), Robertson-Albertyn, S. (Contributor), Phung, T. (Contributor), Mackintosh, A. (Contributor), Finkelbergs, D. (Contributor), Floyd, A. (Contributor), Mol Avelar Tamaki, G. (Contributor), Ridgway, M. (Contributor), Brady, J. (Contributor), Monteiro Do Carmo, R. (Contributor), Hepburn, C. (Contributor), Simeons, F. (Contributor), Hu, X. (Contributor), Kasciukovic, T. (Contributor) & Forkuo, A. (Contributor)
2022Activity: Other activity types › Public engagement and outreach - festival/exhibition