Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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What Is The Structural Basis Of HRI Activation By 1-Phenyl-3-(4-Phenoxy)Cyclohexyl)Ureas?
Masson, G. (Investigator)
31/03/23 → 30/07/25
Project: Research
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Establishment of Cryo-EM Screening Facility At University Of Dundee (Equipment Grant)
Kulathu, Y. (Investigator), Labib, K. (Investigator), Masson, G. (Investigator), Moraga Gonzalez, I. (Investigator), Murray, D. (Investigator), Owen-Hughes, T. (Investigator), Stanley-Wall, N. (Investigator) & Wyatt, P. (Investigator)
1/12/21 → 31/12/26
Project: Research
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Structural Mechanisms Of Nutritional Sensing And Regulation In Cancer Cells
Masson, G. (Investigator) & Petty, R. (Investigator)
Project: Research
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The Role Of GCN2 In Malignant Pleural Mesothelioma
Masson, G. (Investigator)
1/06/22 → 31/05/23
Project: Research
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Purchase of Sample Handling Robot And Mass Spec For Structural Spectrometry Drug Screening
Ferguson, M. (Investigator) & Masson, G. (Investigator)
Biotechnology and Biological Sciences Research Council
1/06/21 → 31/05/22
Project: Research
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An Integrated Stress Response-independent role of GCN2 prevents excessive ribosome biogenesis and mRNA translation
Masson, G., 13 Sept 2024, BioRxiv.Research output: Working paper/Preprint › Preprint
Open AccessFile22 Downloads (Pure) -
ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding
Gong, G. Q., Masson, G. R., Lee, W.-J., Dickson, J. M. J., Kendall, J. D., Rathinaswamy, M. K., Buchanan, C. M., Middleditch, M., Owen, B. M., Spicer, J. A., Rewcastle, G. W., Denny, W. A., Burke, J. E., Shepherd, P. R., Williams, R. L. & Flanagan, J. U. (Lead / Corresponding author), Dec 2024, In: Biochemical Journal. 481, 23, p. 1787-1802 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)21 Downloads (Pure) -
Heme binding causes structural rearrangements in HRI to inhibit activation via autophosphorylation
Kanta, S., Vinciauskaite, V., Neill, G., Muqit, M. M. K. & Masson, G. R. (Lead / Corresponding author), 14 Aug 2024, BioRxiv.Research output: Working paper/Preprint › Preprint
File43 Downloads (Pure) -
Paradoxical Activation of GCN2 by ATP-competitive inhibitors via allosteric activation and autophosphorylation
Neill, G., Vinciauskaite, V., Paul, M., Gilley, R., Cook, S. J. & Masson, G. (Lead / Corresponding author), 15 Aug 2024, BioRxiv, 24 p.Research output: Working paper/Preprint › Preprint
File140 Downloads (Pure) -
RAF inhibitors activate the integrated stress response by direct activation of GCN2
Gilley, R. (Lead / Corresponding author), Kidger, A., Neill, G., Severson, P., Byrne, D., Kenneth, N. S., Bollag, G., Zhang, C., de Oliveira, T., Eyers, P., Bayliss, R., Masson, G. & Cook, S. J. (Lead / Corresponding author), 16 Aug 2024, BioRxiv, 63 p.Research output: Working paper/Preprint › Preprint
File28 Downloads (Pure)
Activities
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BMSS Scotland Special Interest Group
Masson, G. (Invited speaker)
15 Nov 2024Activity: Participating in or organising an event types › Participation in conference
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BMSS Biomacromolecular Structure SIG meeting 2024
Masson, G. (Organiser)
24 Oct 2024Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Overcoming autoinhibition: how can we activate kinases?
Masson, G. (Speaker)
7 Mar 2024Activity: Talk or presentation types › Invited talk
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Structural basis of paradoxical activation of ISR kinases by small molecule RAF inhibitors
Masson, G. (Speaker)
31 Oct 2024Activity: Talk or presentation types › Invited talk
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Scottish Biological Mass Spectrometry Meeting
Masson, G. (Organiser)
3 Nov 2023Activity: Participating in or organising an event types › Participation in conference