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Sapkota, Gopal

Dr

  • Scientific Programme Leader (MRC), MRC PPU
 https://orcid.org/0000-0001-9931-3338

  • United Kingdom

20002020

Research output per year

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Projects

Determining the ligase and DUB landscape of mitochondrial and alpha-synuclein turnover

Ganley, I., Sapkota, G. & Virdee, S.

1/10/20 → 30/09/22

Project: Research

Investigating the Druggability of Undruggable Targets Using the Affinity Directed Protein Missile System (AdPROM) in Neurodegenerative Disorders

Muqit, M. & Sapkota, G.

10/09/18 → 9/09/21

Project: Research

Novel PROTAC-based Chemical Biology Approaches to Induced Protein Knockdown Across the Proteome (PhD Studentship - with Boehringer Ingelheim)

Ciulli, A. & Sapkota, G.

3/09/18 → 2/09/22

Project: Research

MRC QQR

Alessi, D., Davies, P., Ganley, I., Kulathu, Y., Labib, K., Rouse, J., Rousseau, A., Sapkota, G., Virdee, S. & Walden, H.

Medical Research Council

1/04/18 → 31/03/23

Project: Research

Research Output

  • 42 Article
  • 3 Review article
  • 2 Chapter (peer-reviewed)

Characterisation of the biochemical and cellular roles of native and pathogenic amelogenesis imperfecta mutants of FAM83H

Tachie-Menson, T., Gázquez-Gutiérrez, A., Fulcher, L., Macartney, T., Wood, N., Varghese, J., Gourlay, R., Filipe Soares, R. & Sapkota, G., Aug 2020, In : Cellular Signalling. 72, p. 1-17 17 p., 109632.

Research output: Contribution to journal › Article

Open Access
File
    • 1 Citation (Scopus)
    26 Downloads (Pure)

    Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile System

    Simpson, L. M., Macartney, T. J., Nardin, A., Fulcher, L. J., Röth, S., Testa, A., Maniaci, C., Ciulli, A., Ganley, I. G. & Sapkota, G. P., 17 Sep 2020, In : Cell Chemical Biology. 27, 9, p. 1164-1180.e5 17 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 11 Downloads (Pure)

    Mitotic kinase anchoring proteins: the navigators of cell division

    Fulcher, L. & Sapkota, G., 3 Mar 2020, In : Cell Cycle. 19, 5, p. 505-524 20 p.

    Research output: Contribution to journal › Review article

    • 1 Citation (Scopus)

    Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses

    Hutchinson, L. D., Darling, N. J., Nicolaou, S., Gori, L., Squair, D. R., Cohen, P., Hill, C. S. & Sapkota, G. P., 22 Jan 2020, In : Cell Death and Disease. 11, p. 1-17 17 p., 49.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 2 Citations (Scopus)
    51 Downloads (Pure)

    Targeting Endogenous K-RAS for Degradation through the Affinity-Directed Protein Missile System

    Roth, S., Macartney, T., Konopacka, A., Chan, K-H., Zhou, H., Queisser, M. A. & Sapkota, G., 17 Sep 2020, In : Cell Chemical Biology. 27, 9, p. 1151-1163.e6 13 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 168 Downloads (Pure)