Sapkota, Gopal

Dr

  • Scientific Programme Leader (MRC), MRC PPU
  • United Kingdom

20002023
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  • 5 Similar Profiles
Phosphorylation Chemical Compounds
Bone Morphogenetic Proteins Medicine & Life Sciences
Casein Kinase I Medicine & Life Sciences
Protein Kinases Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Proteins Medicine & Life Sciences
Clustered Regularly Interspaced Short Palindromic Repeats Medicine & Life Sciences
Peutz-Jeghers Syndrome Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2018 2023

Research Output 2000 2019

  • 37 Article
  • 2 Chapter (peer-reviewed)
  • 2 Review article
1 Citation (Scopus)
146 Downloads (Pure)

Advances in targeted degradation of endogenous proteins

Roth, S., Fulcher, L. & Sapkota, G., 27 Apr 2019, In : Cellular and Molecular Life Sciences. 76, 14, p. 2761-2777 17 p.

Research output: Contribution to journalReview article

Open Access
File
Proteolysis
Proteins
Clustered Regularly Interspaced Short Palindromic Repeats
Gene Targeting
Protein Biosynthesis
25 Downloads (Pure)

FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning

Fulcher, L. J., He, Z., Mei, L., Macartney, T. J., Wood, N. T., Prescott, A. R., Whigham, A., Varghese, J., Gourlay, R., Ball, G., Clarke, R., Campbell, D., Maxwell, C. A. & Sapkota, G. P., 24 Jul 2019, In : EMBO Reports. p. 1-19 19 p., e47495.

Research output: Contribution to journalArticle

Open Access
File
Casein Kinase I
Spindle Apparatus
Phosphotransferases
Cells
Mitosis
1 Citation (Scopus)

Characterization of Protein Complexes Using Chemical Cross-Linking Coupled Electrospray Mass Spectrometry

Cummins, T. D. & Sapkota, G. P., 1 Jan 2018, Tissue Proteomics: Methods and Protocols. Sarwal, M. & Sigel, T. (eds.). New York: Humana Press, Vol. 1788. p. 43-61 19 p. (Methods in Molecular Biology; vol. 1788).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Mass Spectrometry
Green Fluorescent Proteins
Proteomics
Proteins
Tetracycline
1 Downloads (Pure)

Generation of endogenous BMP transcriptional reporter cells through CRISPR/Cas9 genome editing

Hutchinson, L. D., Bozatzi, P., Macartney, T. & Sapkota, G. P., 2018, Bone Morphogenetic Proteins: Methods and Protocols. Rogers, M. B. (ed.). New York: Humana Press, Vol. 1891. p. 29-35 7 p. (Methods in Molecular Biology; vol. 1891).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Open Access
File
Clustered Regularly Interspaced Short Palindromic Repeats
Bone Morphogenetic Proteins
Chromatin
Complementary DNA
Firefly Luciferases
10 Citations (Scopus)
94 Downloads (Pure)

PAWS1controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP

Cummins, T. D., Wu, K. Z. L., Bozatzi, P., Dingwell, K. S., Macartney, T. J., Wood, N. T., Varghese, J., Gourlay, R., Campbell, D. G., Prescott, A., Griffis, E., Smith, J. C. & Sapkota, G. P., 10 Jan 2018, In : Journal of Cell Science. 131, 1, p. 1-12 12 p., jcs202390.

Research output: Contribution to journalArticle

Open Access
File
Cell Movement
Actins
Clustered Regularly Interspaced Short Palindromic Repeats
Focal Adhesions
Osteosarcoma

Thesis

File

Elucidating the biological function of the uncharacterised protein FAM83G/PAWS1: Role in Wnt signalling through its interaction with Caseine Kinase 1α

Author: Bozatzi, P., 2018

Supervisor: Sapkota, G. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

The regulation of TGFβ/BMP signalling by deubiquitylating enzymes

Author: Herhaus, L., 2014

Supervisor: Sapkota, G. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File