Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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MRC QQR 2024-29
Alessi, D. (Investigator), Davies, P. (Investigator), Ganley, I. (Investigator), Kulathu, Y. (Investigator), Liang, A. (Investigator), Rouse, J. (Investigator), Sapkota, G. (Investigator), Swamy, M. (Investigator), Swatek, K. (Investigator) & Virdee, S. (Investigator)
Project: Research
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Determining the ligase and DUB landscape of mitochondrial and alpha-synuclein turnover
Ganley, I. (Investigator), Sapkota, G. (Investigator) & Virdee, S. (Investigator)
1/12/20 → 29/02/24
Project: Research
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Investigating the Druggability of Undruggable Targets Using the Affinity Directed Protein Missile System (AdPROM) in Neurodegenerative Disorders
Muqit, M. (Investigator) & Sapkota, G. (Investigator)
10/09/18 → 9/09/21
Project: Research
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Novel PROTAC-based Chemical Biology Approaches to Induced Protein Knockdown Across the Proteome (PhD Studentship - with Boehringer Ingelheim)
Ciulli, A. (Investigator) & Sapkota, G. (Investigator)
1/09/18 → 2/09/22
Project: Research
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MRC QQR
Alessi, D. (Investigator), Davies, P. (Investigator), Ganley, I. (Investigator), Kulathu, Y. (Investigator), Labib, K. (Investigator), Liang, A. (Investigator), Rouse, J. (Investigator), Rousseau, A. (Investigator), Sapkota, G. (Investigator), Virdee, S. (Investigator) & Walden, H. (Investigator)
1/04/18 → 1/04/24
Project: Research
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AMPK promotes TFEB transcriptional activity through dephosphorylation at both MTORC1-dependent and -independent sites
Negoita, F., Fraguas Bringas, C., Hellberg, K., Luda, K. M., Liu, H., Li, Z., Cuenco, J., Zhao, J. F., Sathe, G., Ganley, I. G., Sapkota, G. P. & Sakamoto, K. (Lead / Corresponding author), 9 Feb 2026, (E-pub ahead of print) In: Autophagy.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)142 Downloads (Pure) -
HMMR/RHAMM recruits SACK1D/FAM83D-CK1α complex at the mitotic spindle to control spindle alignment
Cartwright, T. N., Nakarakanti, N. K., Dunbar, K., Fulcher, L. J., Bader, S., Wood, N. T., Macartney, T. J. & Sapkota, G. (Lead / Corresponding author), 16 Jan 2026, In: iScience. 29, 1, 19 p., 114417.Research output: Contribution to journal › Article › peer-review
Open Access -
Mutations within the predicted 1 fragment-binding region of FAM83G/SACK1G abolish its interaction with the Ser/Thr kinase CK1α
Utges, J. S., Lee Zhi Xuan, D., Le Chatelier, B., Glennie, L., Macartney, T. J., Wood, N. T., Barton, G. J. (Lead / Corresponding author) & Sapkota, G. P. (Lead / Corresponding author), 7 Jan 2026, In: Open Biology. 16, 1, 14 p., 250230.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Downloads (Pure) -
The contribution of native protein complexes to targeted protein degradation
Glennie, L., Curnutt, N., Sathe, G., Le Chatelier, B., Goff, F., Zhao, J.-F., Cartwright, T., Dunbar, K., Wood, N., Macartney, T., Sapkota, G. (Lead / Corresponding author) & Woo, C., 15 May 2026, In: ACS Chemical Biology. 21, 5, p. 1095-1111 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Downloads (Pure) -
Design and Synthesis of Novel Candidate CK1δ Proteolysis Targeting Chimeras (PROTACs)
Arnold, M., Thompson, T., Glennie, L., Hollnagel, M., Sapkota, G. & Peifer, C. (Lead / Corresponding author), 17 Nov 2025, In: Molecules. 30, 22, 27 p., 4452.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Downloads (Pure)
Datasets
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The contribution of native protein complexes to targeted protein degradation
Glennie, L. (Creator), Curnutt, N. (Creator), Sathe, G. (Creator), Le Chatelier, B. (Creator), Goff, F. (Creator), Zhao, J.-F. (Creator), Cartwright, T. (Creator), Dunbar, K. (Creator), Wood, N. (Creator), Macartney, T. (Creator), Woo, C. (Creator) & Sapkota, G. (Creator), Mendeley Data, 29 Jan 2026
DOI: 10.17632/3zygrwcj4t
Dataset
Prizes
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Industry and Academic Collaboration Award
Sapkota, G. (Recipient), 4 Apr 2024
Prize: Prize (including medals and awards)
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Life Sciences Work Experience Week 2022
Hardee, E. (Organiser), Bergkessel, M. (Participant), Rosazza, T. (Participant), McSorley, H. (Participant), Rasmussen, K. (Participant), Kocaturk, N. (Participant), Crawley, P. (Participant), Agrotis, A. (Participant), Rousseau, A. (Participant), Sapkota, G. (Participant), Glennie, L. (Participant), Hannan, M. (Participant), Appleton, P. (Participant), Tamaki, F. (Participant) & Newton, I. (Participant)
25 Jul 2022 → 29 Jul 2022Activity: Other activity types › Schools engagement
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Discovery Days 2022
Urch, J. (Organiser), Gillespie, I. (Chair), Preshaw, P. (Presenter), Gorrill, H. (Presenter), Coulthurst, S. (Presenter), Arshed, N. (Presenter), Sapkota, G. (Presenter), Valentine, E. (Presenter), Virdee, S. (Presenter), Petrie, K. (Presenter), Brown, M. (Presenter), Hackman, L. (Presenter), O'Neill, S. (Presenter), Sanchez Avila, A. (Presenter), Grubb, B. (Chair), Rowan, J. (Chair), Preston, E. (Contributor) & Wasim, S. (Organiser)
12 Jan 2022 → 14 Jan 2022Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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