Keyphrases
LysR Family
100%
Molecular Targets
90%
Leishmania Donovani
90%
Cell-free Lysate
75%
Demethylase
75%
Resistance Mapping
75%
Diaminothiazoles
75%
Sterols
75%
Human African Trypanosomiasis
75%
Cytochrome P450 Reductase
75%
CYP51
75%
Pullout
75%
Mass Spectrometry
75%
Plasmodium Falciparum
75%
Parallel Profiling
75%
Specific Resistance
75%
Saturation mutagenesis
75%
Resistance Profiling
75%
Resistance mutations
75%
Plasmodium
75%
Partial Efficacy
75%
Mouse Model
75%
Antitrypanosomal Activity
75%
Chronic Chagas Disease
75%
Quinazoline
75%
Lysate
50%
Drug Target
49%
Resistant Clones
45%
Amphotericin B
45%
Trypanosoma Cruzi (T. cruzi)
45%
ATP-binding Pocket
39%
Ergosterol
30%
Mechanism of Action
30%
Total Sterols
30%
HyPer
30%
Cytocidal
30%
New Drugs
30%
Chagas Disease
30%
Neglected Diseases
30%
Quantitative Proteomics
24%
Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS)
24%
Resin
24%
LC-MS Analysis
24%
Protein Enrichment
24%
Drug-treated
24%
Binding Protein
24%
Sample Fractionation
24%
Proof of Concept Study
24%
Transfection Efficiency
24%
Genetic Validation
24%
Biochemistry, Genetics and Molecular Biology
Mass Spectrometry
75%
Cell Lysate
75%
Leishmania donovani
75%
Cytochrome P450 Reductase
75%
Lanosterol 14 Alpha-Demethylase
75%
Sterol
75%
Mutagenesis
75%
Plasmodium
75%
Wild Type
62%
Enzyme
50%
Tandem Mass Spectrometry
37%
Liquid Chromatography-Mass Spectrometry
37%
Adenosine Triphosphate
37%
Drug Resistance
37%
Amino Acids
37%
Transfection
37%
Plasmid
37%
Genetics
37%
Transfer RNA
37%
Ergosterol
24%
Plasmodium falciparum
18%
Fractionation
18%
Quantitative Proteomics
18%
Protein Enrichment
18%
Allele
12%
Amastigote
12%
Anabolism
12%
Whole Genome Sequencing
12%
Cell Membrane
12%
Electron Transport
12%
Methyltransferase
12%
Pharmacology, Toxicology and Pharmaceutical Science
Hexachlorophene
75%
Quinazoline Derivative
75%
Mouse Model
75%
Lysine Transfer RNA Ligase
75%
Antitrypanosomal
75%
Chagas Disease
75%
African Trypanosomiasis
75%
Quinazoline
75%
Infection
71%
Cytostatic
30%
Trypanosomatidae
18%
Trypanosoma Cruzi
18%
Protozoon
18%
Leishmania donovani
18%
Adenosine Triphosphate
18%
Neglected Disease
18%
Pharmacokinetics
15%
Phosphotransferase
15%
Blood-Brain Barrier
15%
Inositol
15%
Structure Activity Relationship
15%
Trypanosoma Brucei
15%
Molecular Target
15%