Projects per year
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Projects
Role of AMPK in Nutrient Sensing and in Cancer (Investigator Award Renewal)
1/10/17 → 30/09/22
Project: Research
Research Output
AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner
Seabright, A. P., Fine, N. H. F., Barlow, J. P., Lord, S. O., Musa, I., Gray, A., Bryant, J. A., Banzhaf, M., Lavery, G. G., Hardie, D. G., Hodson, D. J., Philp, A. & Lai, Y-C., 22 Mar 2020, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 18 p.Research output: Contribution to journal › Article
Open Access
File
AMPK and TOR: the Yin and Yang of cellular nutrient sensing and growth control
González, A., Hall, M. N., Lin, S-C. & Hardie, G., 3 Mar 2020, In : Cell Metabolism. 31, 3, p. 472-492 21 p.Research output: Contribution to journal › Review article
Glucose Starvation Blocks Translation at Multiple Levels
Zhang, C. S., Hardie, D. G. & Lin, S. C., 4 Feb 2020, In : Cell Metabolism. 31, 2, p. 217-218 2 p.Research output: Contribution to journal › Review article
Mechanism of Activation of AMPK by Cordycepin
Hawley, S. A., Ross, F. A., Russell, F. M., Atrih, A., Lamont, D. & Hardie, D. G., 20 Feb 2020, In : Cell Chemical Biology. 27, 2, p. 214-222.e4 14 p.Research output: Contribution to journal › Article
Open Access
File
Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress
Zong, Y., Zhang, C-S., Li, M., Wang, W., Wang, Z., Hawley, S. A., Ma, T., Feng, J-W., Tian, X., Qi, Q., Wu, Y-Q., Zhang, C., Ye, Z., Lin, S-Y., Piao, H-L., Hardie, D. G. & Lin, S-C., 4 Apr 2019, In : Cell Research. 29, p. 460-473 14 p.Research output: Contribution to journal › Article
Open Access
File
8
Citations
(Scopus)
89
Downloads
(Pure)
Activities
The Conversation Article: Zombie caterpillar fungus may contain anti-cancer drug – but there are still questions to be answered
Grahame Hardie (Contributor)3 Mar 2020
Activity: Other activity types › Public engagement and outreach - media article or participation
The Conversation: AMPK: new research into cancer’s ‘good cop/bad cop’ protein could help develop more effective drugs
Grahame Hardie (Contributor)16 Aug 2019
Activity: Other activity types › Public engagement and outreach - media article or participation
IMPAKT 2010 Breast Cancer Conference
David Grahame Hardie (Keynote/plenary speaker)8 May 2010
Activity: Participating in or organising an event types › Participation in conference
Press / Media
New research highlights benefits of old medicine
David Grahame Hardie & Andrew D. Morris
3/05/12
1 item of Media coverage
Press/Media: Research
Thesis
Canonical and non-canonical regulation of AMP-activated protein kinase
Author: Auciello, F. R., 2015Supervisor: Hardie, D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
Regulation and role of the LKB1-AMPK pathway
Author: Gowans, G. J., 2014Supervisor: Hardie, D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
The AMPK signalling pathway in cancer and DNA damage
Author: Dandapani, M., 2013Supervisor: Hardie, D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File