Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Grahame Hardie is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Role of AMPK in Nutrient Sensing and in Cancer (Investigator Award Renewal)
1/10/17 → 1/05/23
Project: Research
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Non-canonical Pathways for Regulation of AMPK (Senior Investigator Award)
1/04/12 → 30/09/17
Project: Research
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Unraveling the Role of AMPK as a Hypothalamic Glucose-Sensor
Ashford, M., Hardie, G. & McCrimmon, R.
1/05/11 → 31/12/12
Project: Research
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AMP-activated protein kinase
Hardie, G., 7 Jan 2022, Encyclopedia of Molecular Pharmacology. Offermanns, S. & Rosenthal, W. (eds.). 3 ed. Switzerland: Springer , p. 90-96 7 p.Research output: Chapter in Book/Report/Conference proceeding › Entry for encyclopedia/dictionary
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Calcium/calmodulin-dependent protein kinase kinase 2 mediates pleiotropic effects of epidermal growth factor in cancer cells
Dai, S., Venturini, E., Yadav, S., Lin, X., Clapp, D., Steckiewicz, M., Gocher-Demske, A. M., Hardie, D. G. & Edelman, A. M., Jul 2022, In: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1869, 7, 14 p., 119252.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Downloads (Pure) -
Caspase cleavage and nuclear retention of the energy sensor AMPK-α1 during apoptosis
Cheratta, A. R., Thayyullathil, F., Hawley, S. A., Ross, F. A., Atrih, A., Lamont, D. J., Pallichankandy, S., Subburayan, K., Alakkal, A., Rezgui, R., Gray, A., Hardie, D. G. & Galadari, S., 3 May 2022, In: Cell Reports. 39, 5, 18 p., 110761.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1
Li, M., Zhang, C. S., Feng, J. W., Wei, X., Zhang, C., Xie, C., Wu, Y., Hawley, S. A., Atrih, A., Lamont, D. J., Wang, Z., Piao, H. L., Hardie, D. G. & Lin, S. C., Apr 2021, In: Cell Research. 31, p. 478-481 4 p.Research output: Contribution to journal › Letter › peer-review
Open AccessFile3 Citations (Scopus)32 Downloads (Pure) -
Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy
Drake, J. C., Wilson, R. J., Laker, R. C., Guan, Y., Spaulding, H. R., Nichenko, A. S., Shen, W., Shang, H., Dorn, M. V., Huang, K., Zhang, M., Bandara, A. B., Brisendine, M. H., Kashatus, J. A., Sharma, P. R., Young, A., Gautam, J., Cao, R., Wallrabe, H., Chang, P. A. & 11 others, , 14 Sep 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 37, 10 p., e2025932118.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)19 Downloads (Pure)
Activities
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The Conversation Article: Zombie caterpillar fungus may contain anti-cancer drug – but there are still questions to be answered
Grahame Hardie (Contributor)
3 Mar 2020Activity: Other activity types › Public engagement and outreach - media article or participation
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The Conversation: AMPK: new research into cancer’s ‘good cop/bad cop’ protein could help develop more effective drugs
Grahame Hardie (Contributor)
16 Aug 2019Activity: Other activity types › Public engagement and outreach - media article or participation
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IMPAKT 2010 Breast Cancer Conference
David Grahame Hardie (Keynote/plenary speaker)
8 May 2010Activity: Participating in or organising an event types › Participation in conference
Press / Media
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New research highlights benefits of old medicine
David Grahame Hardie & Andrew D. Morris
3/05/12
1 item of Media coverage
Press/Media: Research