McLellan, Hazel

Dr

  • United Kingdom

  • 635 Citations
  • 13 h-Index
20072019
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Research Output 2007 2019

  • 635 Citations
  • 13 h-Index
  • 20 Article
  • 1 Chapter
  • 1 Chapter (peer-reviewed)
2019
6 Citations (Scopus)
68 Downloads (Pure)

Phytophthora infestans RXLR effectors act in concert at diverse subcellular locations to enhance host colonization

Wang, S., McLellan, H., Bukharova, T., He, Q., Murphy, F., Shi, J., Sun, S., van Weymers, P., Ren, Y., Thilliez, G., Wang, H., Chen, X., Engelhardt, S., Vleeshouwers, V., Gilroy, E. M., Whisson, S. C., Hein, I., Wang, X., Tian, Z., Birch, P. R. J. & 1 others, Boevink, P. C., 1 Jan 2019, In : Journal of Experimental Botany. 70, 1, p. 343-356 14 p., ery360.

Research output: Contribution to journalArticle

Open Access
File
Phytophthora infestans
Nicotiana benthamiana
Tobacco
pathogens
Infection
45 Downloads (Pure)

Phytophthora infestans RXLR effectors target parallel steps in an immune signal transduction pathway

Ren, Y., Armstrong, M., Qi, Y., McLellan, H., Zhong, C., Du, B., Birch, P. R. J. & Tian, Z., Aug 2019, In : Plant Physiology. 180, 4, p. 2227-2239 13 p.

Research output: Contribution to journalArticle

Open Access
File
Phytophthora infestans
mitogen-activated protein kinase kinase kinase
signal transduction
cell death
Signal Transduction

The oomycete microbe-associated molecular pattern Pep-13 triggers SERK3/BAK1-independent plant immunity

Wang, H., He, H., Qi, Y., McLellan, H., Tian, Z., Birch, P. R. J. & Tian, Z., Feb 2019, In : Plant Cell Reports. 38, 2, p. 173-182 10 p.

Research output: Contribution to journalArticle

brassinosteroids
Oomycetes
phosphotransferases (kinases)
immunity
microorganisms
2018

Correction to: Inhibition of cathepsin B by caspase-3 inhibitors blocks programmed cell death in Arabidopsis

Ge, Y., Cai, Y. M., Bonneau, L., Rotari, V., Danon, A., McKenzie, E. A., McLellan, H., Mach, L. & Gallois, P., 18 Jun 2018, In : Cell Death and Differentiation. 25, 8, p. 1532 1 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
86 Downloads (Pure)

Phytophthora infestans effector SFI3 targets potato UBK to suppress early immune transcriptional responses

He, Q., McLellan, H., Hughes, R. K., Boevink, P. C., Armstrong, M., Lu, Y., Banfield, M. J., Tian, Z. & Birch, P. R. J., 10 Dec 2018, In : New Phytologist. 18 p.

Research output: Contribution to journalArticle

Open Access
File
Phytophthora infestans
Solanum tuberosum
Immunity
immunity
potatoes
6 Citations (Scopus)
80 Downloads (Pure)

Phytophthora infestans RXLR effector SFI5 requires association with calmodulin for PTI/MTI suppressing activity

Zheng, X., Wagener, N., McLellan, H., Boevink, P. C., Hua, C., Birch, P. R. J. & Brunner, F., 1 Sep 2018, In : New Phytologist. 219, 4, p. 1433-1446 14 p.

Research output: Contribution to journalArticle

Open Access
File
Phytophthora infestans
calmodulin
Calmodulin
Immunity
immunity
9 Citations (Scopus)
62 Downloads (Pure)

Plant pathogen effector utilizes host susceptibility factor NRL1 to degrade the immune regulator SWAP70

He, Q., Naqvi, S., McLellan, H., Boevink, P., Champouret, N., Hein, I. & Birch, P., 14 Aug 2018, In : Proceedings of the National Academy of Sciences. 115, 33, p. E7834-E7843 10 p.

Research output: Contribution to journalArticle

Open Access
File
Phytophthora infestans
Immunity
Cell Death
Proteasome Endopeptidase Complex
Guanine Nucleotide Exchange Factors
2017
13 Citations (Scopus)
136 Downloads (Pure)

BTB-BACK Domain Protein POB1 Suppresses Immune Cell Death by Targeting Ubiquitin E3 ligase PUB17 for Degradation

Orosa, B., He, Q., Mesmar, J., Gilroy, E. M., McLellan, H., Yang, C., Craig, A., Bailey, M., Zhang, C., Moore, J. D., Boevink, P. C., Tian, Z., Birch, P. R. J. & Sadanandom, A., 5 Jan 2017, In : PLoS Genetics. 13, 1, p. 1-26 26 p., e1006540.

Research output: Contribution to journalArticle

Open Access
File
ubiquitin-protein ligase
Ubiquitin-Protein Ligases
hypersensitive response
targeting
cell death
2016
44 Citations (Scopus)
196 Downloads (Pure)

A Phytophthora infestans RXLR effector targets plant PP1c isoforms that promote late blight disease

Boevink, P. C., Wang, X., McLellan, H., He, Q., Naqvi, S., Armstrong, M. R., Zhang, W., Hein, I., Gilroy, E. M., Tian, Z. & Birch, P. R. J., 29 Jan 2016, In : Nature Communications. 7, 10311.

Research output: Contribution to journalArticle

Open Access
File
blight
Phytophthora infestans
effectors
Protein Phosphatase 1
Plant Proteins
3 Citations (Scopus)

Engineering Barriers to Infection by Undermining Pathogen Effector Function or by Gaining Effector Recognition

Ahmed, A. A., Mclellan, H., Aguilar, G. B., Hein, I., Thordal-Christensen, H. & Birch, P. R. J., 9 Jun 2016, Plant Pathogen Resistance Biotechnology. Collinge, D. B. (ed.). Wiley, p. 21-50 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pathogens
Plant Immunity
vpr Genes
Pattern Recognition Receptors
Infection
37 Citations (Scopus)
74 Downloads (Pure)

Inhibition of cathepsin B by caspase-3 inhibitors blocks programmed cell death in Arabidopsis

Ge, Y., Cai, Y-M., Bonneau, L., Rotari, V., Danon, A., McKenzie, E. A., McLellan, H., Mach, L. & Gallois, P., 1 Sep 2016, In : Cell Death & Differentiation. 23, 9, p. 1493-1501 9 p.

Research output: Contribution to journalArticle

Open Access
File
Cathepsin B
Caspase Inhibitors
Arabidopsis
Caspase 3
Cell Death
15 Citations (Scopus)
91 Downloads (Pure)

Oomycetes seek help from the plant : phytophthora infestans effectors target host susceptibility factors

Boevink, P. C., McLellan, H., Gilroy, E. M., Naqvi, S., He, Q., Yang, L., Wang, X., Turnbull, D., Armstrong, M. R., Tian, Z. & Birch, P. R. J., 2 May 2016, In : Molecular Plant. 9, 5, p. 636-638 3 p.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)
83 Downloads (Pure)

Potato NPH3/RPT2-like protein StNRL1, targeted by a Phytophthora infestans RXLR effector, is a susceptibility factor

Yang, L., McLellan, H., Naqvi, S., He, Q., Boevink, P. C., Armstrong, M., Giuliani, L. M., Zhang, W., Tian, Z., Zhan, J., Gilroy, E. M. & Birch, P. R. J., May 2016, In : Plant Physiology. 171, 1, p. 645-657 2 p.

Research output: Contribution to journalArticle

Open Access
File
Phytophthora infestans
Solanum tuberosum
cell death
Cell Death
potatoes
2015
21 Citations (Scopus)
103 Downloads (Pure)

A host KH RNA-binding protein is a susceptibility factor targeted by an RXLR effector to promote late blight disease

Wang, X., Boevink, P., McLellan, H., Armstrong, M., Bukharova, T., Qin, Z. & Birch, P. R. J., 7 Sep 2015, In : Molecular Plant. 8, 9, p. 1385-1395 11 p.

Research output: Contribution to journalArticle

Open Access
File
RNA-binding proteins
RNA-Binding Proteins
Phytophthora infestans
Solanum tuberosum
pathogens
25 Citations (Scopus)

U-box E3 ubiquitin ligase PUB17 acts in the nucleus to promote specific immune pathways triggered by Phytophthora infestans

He, Q., McLellan, H., Boevink, P. C., Sadanandom, A., Xie, C., Birch, P. R. J. & Tian, Z., Jun 2015, In : Journal of Experimental Botany. 66, 11, p. 3189-3199 11 p.

Research output: Contribution to journalArticle

Phytophthora infestans
ubiquitin-protein ligase
Ubiquitin-Protein Ligases
Cell Death
immunity
2014
51 Citations (Scopus)
183 Downloads (Pure)

Functionally Redundant RXLR Effectors from Phytophthora infestans Act at Different Steps to Suppress Early flg22-Triggered Immunity

Zheng, X., McLellan, H., Fraiture, M., Liu, X., Boevink, P. C., Gilroy, E. M., Chen, Y., Kandel, K., Sessa, G., Birch, P. R. J. & Brunner, F., 2014, In : PLoS Pathogens. 10, 4, 17 p., e1004057.

Research output: Contribution to journalArticle

Open Access
File
Phytophthora infestans
Immunity
Lycopersicon esculentum
Arabidopsis
MAP Kinase Signaling System
6 Citations (Scopus)

In vivo protein-protein interaction studies with BiFC: conditions, cautions, and caveats

Boevink, P., McLellan, H., Bukharova, T., Engelhardt, S. & Birch, P., 15 Feb 2014, Plant-pathogen interactions: methods and protocols. Birch, P., Jones, J. T. & Bos, J. I. B. (eds.). New York: Humana Press, p. 81-90 10 p. (Methods in Molecular Biology; vol. 1127).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Fluorescence
Proteins
Plant Cells
Confocal Microscopy
80 Citations (Scopus)

Phytophthora infestans RXLR effector PexRD2 interacts with host MAPKKKε to suppress plant immune signaling

King, S. R. F., McLellan, H., Boevink, P. C., Armstrong, M. R., Bukharov, T., Sukarta, O., Win, J., Kamoun, S., Birch, P. R. J. & Banfield, M. J., Mar 2014, In : Plant Cell. 26, 3, p. 1345-1359 15 p.

Research output: Contribution to journalArticle

Phytophthora infestans
mitogen-activated protein kinase kinase kinase
MAP Kinase Kinase Kinases
Plant Immunity
Plant Cells
27 Citations (Scopus)
165 Downloads (Pure)

The role of effectors in nonhost resistance to filamentous plant pathogens

Stam, R., Mantelin, S., McLellan, H. & Thilliez, G., 5 Nov 2014, In : Frontiers in Plant Science. 5, 582.

Research output: Contribution to journalArticle

Open Access
File
plant pathogens
pathogens
Oomycetes
plant breeding
resistance mechanisms
2013
95 Citations (Scopus)

An RxLR Effector from Phytophthora infestans Prevents Re-localisation of Two Plant NAC Transcription Factors from the Endoplasmic Reticulum to the Nucleus

McLellan, H., Boevink, P., Armstrong, M., Pritchard, L., Gomez, S., Morales, J., Whisson, S. & Birch, P. R. J., 10 Oct 2013, In : PLoS Pathogens. 9, 10, e1003670.

Research output: Contribution to journalArticle

Phytophthora infestans
Endoplasmic Reticulum
Transcription Factors
Phytophthora
Virulence
2009
58 Citations (Scopus)

Functional redundancy in the Arabidopsis Cathepsin B gene family contributes to basal defence, the hypersensitive response and senescence

McLellan, H., Gilroy, E. M., Yun, B-W., Birch, P. R. J. & Loake, G. J., 2009, In : New Phytologist. 183, 2, p. 408-418 11 p.

Research output: Contribution to journalArticle

2007
110 Citations (Scopus)

Involvement of cathepsin B in the plant disease resistance hypersensitive response

Gilroy, E. M., Hein, I., Van Der Hoorn, R., Boevink, P. C., Venter, E., McLellan, H., Kaffarnik, F., Hrubikova, K., Shaw, J., Holeva, M., Lopez, E. C., Borras-Hidalgo, O., Pritchard, L., Loake, G. J., Lacomme, C. & Birch, P. R. J., Oct 2007, In : Plant Journal. 52, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Plant Diseases
cathepsin B
Cathepsin B
Disease Resistance
hypersensitive response