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Ellis, Ian

Dr

  • 767 Citations
  • 15 h-Index
1989 …2019
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Research Output 1989 2019

2019
Glandular and Epithelial Neoplasms
Nerve Growth Factor
Phosphatidylinositol 3-Kinases
Cell Movement
Neoplasms
2018
70 Downloads (Pure)
Open Access
File
Mouth Neoplasms
Cell Movement
Neoplasm Metastasis
Keratinocytes
Phosphorylation
2017
7 Citations (Scopus)
111 Downloads (Pure)
Open Access
File
Epithelial-Mesenchymal Transition
Transforming Growth Factors
Epidermal Growth Factor
Cell Movement
Intercellular Signaling Peptides and Proteins
2016
27 Citations (Scopus)
126 Downloads (Pure)

Expression of CDK7, cyclin H and MAT1 is elevated in breast cancer and is prognostic in estrogen receptor- positive breast cancer

Patel, H., Abduljabbar, R., Lai, C. F., Periyasamy, M., Harrod, A., Gemma, C., Steel, J., Patel, N., Busonero, C., Jerjees, D., Remenyi, J., Smith, S., Gomm, J. J., Magnani, L., Gyorffy, B., Jones, J. L., Fuller-Pace, F. V., Shousha, S., Buluwela, L., Rakha, E. A. & 3 others, Ellis, I. O., Coombes, R. C. & Ali, S., 1 Dec 2016, In : Clinical Cancer Research. 22, 23, p. 5929-5938 10 p.

Research output: Contribution to journalArticle

Open Access
File
Cyclin H
Cyclin-Dependent Kinases
Estrogen Receptors
Estrogen Receptor alpha
Breast Neoplasms
2 Citations (Scopus)
154 Downloads (Pure)
Open Access
File
Root Caries
Integrins
Glass
Collagen
Compressive Strength
2014
5 Citations (Scopus)
127 Downloads (Pure)
Open Access
File
Tobacco
Alcohols
Phosphorylation
Smoking
Immunohistochemistry
11 Citations (Scopus)

Is there a pAkt between VEGF and oral cancer cell migration?

Islam, M. R., Jones, S. J., Macluskey, M. & Ellis, I. R., Jun 2014, In : Cellular Signalling. 26, 6, p. 1294-1302 9 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Vascular Endothelial Growth Factor A
Cell Movement
Phosphorylation
Cell Line
2013
297 Downloads (Pure)

The alternate GNB3 splice variant, Gβ3s, exhibits an altered signalling response to EGF stimulation, which leads to enhanced cell migration

Tummala, H., Khalil, H. S., Islam, M. R., Jones, S. J., Ellis, I. R., D'Ascanio, I., Zhelev, N. & Lester, D. H., 30 Nov 2013, In : Biodiscovery. 9, 3, p. 1-22 22 p.

Research output: Contribution to journalArticle

Open Access
File
Epidermal Growth Factor
Cell Movement
70-kDa Ribosomal Protein S6 Kinases
Phosphorylation
Phenotype
8 Citations (Scopus)

The control and importance of hyaluronan synthase expression in palatogenesis

Galloway, J. L., Jones, S. J., Mossey, P. A. & Ellis, I. R., 2013, In : Frontiers in Physiology. 4, 11 p., 10.

Research output: Contribution to journalArticle

Hyaluronic Acid
Palate
Extracellular Matrix
Epithelium
Cleft Palate
2012
5 Citations (Scopus)
Transforming Growth Factors
Extracellular Matrix
Fibroblasts
Collagen Type I
Stromal Cells
2011
24 Citations (Scopus)

Cooperative Binding and Activation of Fibronectin by a Bacterial Surface Protein

Marjenberg, Z. R., Ellis, I. R., Hagan, R. M., Prabhakaran, S., Hoeoek, M., Talay, S. R., Potts, J. R., Staunton, D. & Schwarz-Linek, U., 21 Jan 2011, In : Journal of Biological Chemistry. 286, 3, p. 1884-1894 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Migration-stimulating factor as a novel biomarker in salivary gland tumours

Aljorani, L. E., Bankfalvi, A., Carey, F. A., Harada, K., Ohe, G., Jones, S. J., Ellis, I. R., Schor, S. L. & Schor, A. M., Nov 2011, In : Journal of Oral Pathology and Medicine. 40, 10, p. 747-754 8 p.

Research output: Contribution to journalArticle

VEGF and Oral Cancer - ex Vivo and in Vitro Studies

Islam, M., Alkhadar, H., Paterson, Z., Macluskey, M., Jones, S., Mossey, P. & Ellis, I., Sep 2011, In : European Journal of Cancer. 47, S1, p. S570-S571 2 p., 8593.

Research output: Contribution to journalBook/Film/Article review

2010

Expression of migration stimulating factor in breast tissues and its clinical significance

Schor, A. M., Perrier, S., Woolston, A. M., Jones, S. J., Ellis, I. R., Islam, M. R., Kazmi, S., Purdie, C., Thompson, A. M. & Schor, S. L., 2010, In : Breast Cancer Research. 12, Suppl. 1, 1 p., P37.

Research output: Contribution to journalBook/Film/Article review

7 Citations (Scopus)

Migration Stimulating Factor (MSF) promotes fibroblast migration by inhibiting AKT

Ellis, I. R., Jones, S. J., Lindsay, Y., Ohe, G., Schor, A. M., Schor, S. L. & Leslie, N. R., Nov 2010, In : Cellular Signalling. 22, 11, p. 1655-1659 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Multi-factorial modulation of IGD motogenic potential in MSF (Migration Stimulating Factor)

Ellis, I. R., Jones, S. J., Staunton, D., Vakonakis, I., Norman, D. G., Potts, J. R., Milner, C. M., Meenan, N. A. G., Raibaud, S., Ohea, G., Schor, A. M. & Schor, S. L., 10 Sep 2010, In : Experimental Cell Research. 316, 15, p. 2465-2476 12 p.

Research output: Contribution to journalArticle

2009
41 Citations (Scopus)

Motogenic Sites in Human Fibronectin Are Masked by Long Range Interactions

Vakonakis, I., Staunton, D., Ellis, I. R., Sarkies, P., Flanagan, A., Schor, A. M., Schor, S. L. & Campbell, I. D., 5 Jun 2009, In : Journal of Biological Chemistry. 284, 23, p. 15668-15675 8 p.

Research output: Contribution to journalArticle

The expression of vascular endothelial growth factor A (VEGFA) and C (VEGFC) and their receptors in head and neck squamous cell carcinoma

Macluskey, M., Jones, S., Stenhouse, G., McLoughlin, P., Ellis, I. & Alkhadar, H., Jul 2009, In : Oral Oncology. p. 212-212 1 p.

Research output: Contribution to journalBook/Film/Article review

1 Citation (Scopus)

The Oncofetal Paradigm Revisited: MSF and HA as Contextual Drivers of Cancer Progression

Schor, S. L., Schor, A. M., Ellis, I. R., Jones, S. J., Florence, M., Cox, J. & Woolston, A-M., 2009, Hyaluronan in cancer biology. San Diego, CA.: Academic Press, p. 283-306 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Hyaluronic Acid
Neoplasms
Angiogenesis Inducing Agents
Pathologic Processes
Stromal Cells
2008
17 Citations (Scopus)

Differential involvement of TGF-β1 in mediating the motogenic effects of TSP-1 on endothelial cells, fibroblasts and oral tumour cells

Motegi, K., Harada, K., Ohe, G., Jones, S. J., Ellis, I. R., Crouch, D. H., Schor, S. L. & Schor, A. M., 1 Aug 2008, In : Experimental Cell Research. 314, 13, p. 2323-2333 11 p.

Research output: Contribution to journalArticle

Identification and role of migration stimulating factor isoforms in breast carcinomas

Schor, A. M., Ellis, I. R., Jones, S. J., Perrier, S., Florence, M. M., Cox, J., Ohe, G., Kankova, K., Vojtesek, B., Thompson, A. M., Purdie, C., Kazmi, S., Foo, S., Woolston, A-M. & Schor, S. L., 2008, In : Breast Cancer Research. 10, Suppl.2, 1 p., P66.

Research output: Contribution to journalBook/Film/Article review

25 Citations (Scopus)

Individually addressable microelectrode array for monitoring oxygen and nitric oxide release

Patel, B. A., Arundell, M., Quek, R. G. W., Harvey, S. L. R., Ellis, I. R., Florence, M. M., Cass, A. E. G., Schor, A. M. & O'Hare, D., Mar 2008, In : Analytical and Bioanalytical Chemistry. 390, 5, p. 1379-1387 9 p.

Research output: Contribution to journalArticle

Migration Stimulating Factor (MSF) as a mediator of Epithelial-Stromal interactions in human tumours

Schor, A. M., Ellis, I. R., Jones, S. J., Perrier, S., Ohe, G. & Schor, S. S., 2008, In : Anticancer Research. 28, 5C, p. 3480-3481 2 p., 602.

Research output: Contribution to journalBook/Film/Article review

2007
9 Citations (Scopus)

Co-expression by keratinocytes of migration stimulating factor (MSF) and a functional inhibitor of its bioactivity (MSFI)

Jones, S. J., Florence, M. M., Ellis, I. R., Kankova, K., Schor, S. L. & Schor, A. M., 10 Dec 2007, In : Experimental Cell Research. 313, 20, p. 4145-4157 13 p.

Research output: Contribution to journalArticle

Keratinocytes
Conditioned Culture Medium
Fibroblasts
Wound Healing
Neoplasms
32 Citations (Scopus)

EGF AND TGF-α motogenic activities are mediated by the EGF receptor via distinct matrix-dependent mechanisms

Ellis, I. R., Schor, A. M. & Schor, S. L., 15 Feb 2007, In : Experimental Cell Research. 313, 4, p. 732-741 10 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Epidermal Growth Factor
Cytokines
CD44 Antigens
70-kDa Ribosomal Protein S6 Kinases
27 Citations (Scopus)

The role of the fibronectin IGD motif in stimulating fibroblast migration

Millard, C. J., Ellis, I. R., Pickford, A. R., Schor, A. M., Schor, S. L. & Campbell, I. D., 7 Dec 2007, In : Journal of Biological Chemistry. 282, 49, p. 35530-35535 6 p.

Research output: Contribution to journalArticle

Fibroblasts
Fibronectins
Protein Isoforms
Nuclear magnetic resonance
Mutation
2006
24 Citations (Scopus)

A novel “sandwich” assay for quantifying chemo-regulated cell migration within 3-dimensional matrices: Wound healing cytokines exhibit distinct motogenic activities compared to the transmembrane assay

Schor, S. L., Ellis, I. R., Harada, K., Motegi, K., Anderson, S., Chaplain, M. A. J., Keatch, R. P. & Schor, A. M., May 2006, In : Cell Motility and the Cytoskeleton. 63, 5, p. 287-300 14 p.

Research output: Contribution to journalArticle

Wound Healing
Cell Movement
Cytokines
Collagen Type I
Transforming Growth Factor beta

Evaluation of migration-stimulating factor expression for breast cancer diagnosis and prognosis

Jones, S. J., Ellis, I. R., Kankova, K., Thompson, A. M., Preece, P., Kazmi, S., Schor, S. L. & Schor, A. M., 2006, In : Breast Cancer Research. 8, Suppl.2, p. S11-S11 1 p., P19.

Research output: Contribution to journalMeeting abstract

2005
5 Citations (Scopus)

Synthesis of an IGD peptidomimetic with motogenic activity

Shpiro, N., Ellis, I. R., Dines, T. J., Schor, A. M., Schor, S. L., Norman, D. G. & Marquez, R., 2005, In : Molecular BioSystems. 1, 4, p. 318-320 3 p.

Research output: Contribution to journalArticle

Peptidomimetics
22 Citations (Scopus)

The expression of migration stimulating factor, a potent oncofetal cytokine, is uniquely controlled by 3′-untranslated region–dependent nuclear sequestration of its precursor messenger RNA

Kay, R. A., Ellis, I. R., Jones, S. J., Perrier, S., Florence, M. M., Schor, A. M. & Schor, S. L., Dec 2005, In : Cancer Research. 65, 23, p. 10742-10749 8 p.

Research output: Contribution to journalArticle

RNA Precursors
Cytokines
Messenger RNA
3' Untranslated Regions
Fibroblasts
2003
83 Citations (Scopus)

Migration-stimulating factor: a genetically truncated onco-fetal fibronectin isoform expressed by carcinoma and tumor-associated stromal cells

Schor, S. L., Ellis, I. R., Jones, S. J., Baillie, R., Seneviratne, K., Clausen, J., Motegi, K., Vojtesek, B., Kankova, K., Furrie, E., Sales, M. J., Schor, A. M. & Kay, R. A., Dec 2003, In : Cancer Research. 63, 24, p. 8827-8836 10 p.

Research output: Contribution to journalArticle

Stromal Cells
Fibronectins
Protein Isoforms
Carcinoma
Complementary DNA
2001

Chemotaxis and Chemokinesis in 3D Macromolecular Matrices: Relevance to Angiogenesis

Schor, A. M., Ellis, I. & Schor, S. L., 2001, Angiogenesis Protocols. Murray, J. C. (ed.). Humana Press, p. 163-83 21 p. (Methods in Molecular Medicine; vol. 46).

Research output: Chapter in Book/Report/Conference proceedingChapter

Chemotaxis
Pericytes
Fibroblasts
Extracellular Matrix
Blood Vessels

Collagen gel assay for angiogenesis: induction of endothelial cell sprouting

Schor, A. M., Ellis, I. & Schor, S. L., 2001, Angiogenesis Protocols. Murray, J. C. (ed.). Humana Press, p. 145-62 18 p. (Mathods in Molecular Medicine; vol. 46).

Research output: Chapter in Book/Report/Conference proceedingChapter

Collagen
Endothelial Cells
Gels
Endothelium
Blood Vessels
1999
33 Citations (Scopus)

Motogenic activity of IGD-containing synthetic peptides

Schor, S. L., Ellis, I., Banyard, J. & Schor, A. M., 1999, In : Journal of Cell Science. 112, 22, p. 3879-88 10 p.

Research output: Contribution to journalArticle

Peptides
Fibroblasts
Gelatin
Collagen Type I
Fibronectins
1996
35 Citations (Scopus)

Substratum-dependent stimulation of fibroblast migration by the gelatin-binding domain of fibronectin

Schor, S. L., Ellis, I., Dolman, C., Banyard, J., Humphries, M. J., Mosher, D. F., Grey, A. M., Mould, A. P., Sottile, J. & Schor, A. M., 1996, In : Journal of Cell Science. 109, 10, p. 2581-90 10 p.

Research output: Contribution to journalArticle

Gelatin
Fibronectins
Fibroblasts
Collagen
Collagen Type I
1994
13 Citations (Scopus)

Fetal-like fibroblasts: their production of migration-stimulating factor and role in tumor progression

Schor, S. L., Grey, A. M., Ellis, I., Schor, A. M., Howell, A., Sloan, P. & Murphy, R., 1994, Mammary Tumorigenesis and Malignant Progression. Dickson, R. B. & Lippman, M. E. (eds.). Boston: Springer US, Vol. 71. p. 277-98 22 p. (Cancer treatment and research).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

1993
13 Citations (Scopus)

Migration stimulating factor (MSF): its structure, mode of action and possible function in health and disease

Schor, S. L., Grey, A. M., Ellis, I., Schor, A. M., Coles, B. & Murphy, R., 1993, In : Symposia of the Society for Experimental Biology. 47, p. 235-51 17 p.

Research output: Contribution to journalReview article

Fibroblasts
Health
Hyaluronic Acid
Gelatin
Fibronectins
1992
78 Citations (Scopus)

Antagonistic effects of TGF-beta 1 and MSF on fibroblast migration and hyaluronic acid synthesis: Possible implications for dermal wound healing

Ellis, I., Grey, A. M., Schor, A. M. & Schor, S. L., Jul 1992, In : Journal of Cell Science. 102, 3, p. 447-56 10 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta1
Hyaluronic Acid
Wound Healing
Fibroblasts
Skin
1991
13 Citations (Scopus)

Heterogeneity amongst fibroblasts in the production of migration stimulating factor (MSF): implications for cancer pathogenesis

Schor, S. L., Grey, A. M., Picardo, M., Schor, A. M., Howell, A., Ellis, I. & Rushton, G., 1991, In : EXS. 59, p. 127-46 20 p.

Research output: Contribution to journalReview article

Fibroblasts
Neoplasms
Hyaluronic Acid
Skin
Hereditary Neoplastic Syndromes
1989
63 Citations (Scopus)

Mechanism of action of the migration stimulating factor produced by fetal and cancer patient fibroblasts: effect on hyaluronic and synthesis

Schor, S. L., Schor, A. M., Grey, A. M., Chen, J., Rushton, G., Grant, M. E. & Ellis, I., Aug 1989, In : In Vitro Cellular & Developmental Biology - Animal. 25, 8, p. 737-46 10 p.

Research output: Contribution to journalArticle

Fibroblasts
Neoplasms
Hyaluronic Acid
Skin Neoplasms
Collagen
124 Citations (Scopus)

Purification of the migration stimulating factor produced by fetal and breast cancer patient fibroblasts

Grey, A. M., Schor, A. M., Rushton, G., Ellis, I. & Schor, S. L., 1 Apr 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 7, p. 2438-42 5 p.

Research output: Contribution to journalArticle

Fibroblasts
Breast Neoplasms
Ammonium Sulfate
Skin
Heparin