Research Output per year
Research Output 1989 2019
2019
Nerve growth factor-induced migration in oral and salivary gland tumour cells utilises the PI3K/Akt signalling pathway: is there a link to perineural invasion?
Alkhadar, H., Macluskey, M., White, S. & Ellis, I., 29 Nov 2019, In : Journal of Oral Pathology and Medicine. 8 p.Research output: Contribution to journal › Article
Glandular and Epithelial Neoplasms
Nerve Growth Factor
Phosphatidylinositol 3-Kinases
Cell Movement
Neoplasms
2018
Is it all just an Akt you’d be SMAD to believe it! Role of TGFβ1 in oral cancer metastasis
Islam, M., Alghamdi, A., Sriramula, P., Shalgm, B., Jones, S. & Ellis, I., 26 Nov 2018, In : Dental Oral Biology and Craniofacial Research. 3, 9 p.Research output: Contribution to journal › Article
Open Access
File
Mouth Neoplasms
Cell Movement
Neoplasm Metastasis
Keratinocytes
Phosphorylation
2017
7
Citations
(Scopus)
111
Downloads
(Pure)
The motogenic effect of EGF and TGF-a on the migration of tumor cells from the oral region: A role of epithelial-to-mesenchymal transition in cancer and a route for translation into the clinic
Islam, M., Mane, S., Hyder, E., Jones, S. & Ellis, I., 27 Mar 2017, In : Translational Research in Oral Oncology. 2, p. 1-9 9 p.Research output: Contribution to journal › Article
Open Access
File
Epithelial-Mesenchymal Transition
Transforming Growth Factors
Epidermal Growth Factor
Cell Movement
Intercellular Signaling Peptides and Proteins
2016
27
Citations
(Scopus)
126
Downloads
(Pure)
Expression of CDK7, cyclin H and MAT1 is elevated in breast cancer and is prognostic in estrogen receptor- positive breast cancer
Patel, H., Abduljabbar, R., Lai, C. F., Periyasamy, M., Harrod, A., Gemma, C., Steel, J., Patel, N., Busonero, C., Jerjees, D., Remenyi, J., Smith, S., Gomm, J. J., Magnani, L., Gyorffy, B., Jones, J. L., Fuller-Pace, F. V., Shousha, S., Buluwela, L., Rakha, E. A. & 3 others, , 1 Dec 2016, In : Clinical Cancer Research. 22, 23, p. 5929-5938 10 p.Research output: Contribution to journal › Article
Open Access
File
Cyclin H
Cyclin-Dependent Kinases
Estrogen Receptors
Estrogen Receptor alpha
Breast Neoplasms
2
Citations
(Scopus)
154
Downloads
(Pure)
Investigating the addition of collagen and its integrin binding sequence (RGD) to glass polyalkenoate; in terms of material and cellular properties to explore a more biocompatible method of root caries restoration
Salem, A. M., Jones, S. J., Ellis, I. R. & Chadwick, R. G., 1 Nov 2016, In : Journal of Dentistry. 54, p. 68-76 9 p.Research output: Contribution to journal › Article
Open Access
File
Root Caries
Integrins
Glass
Collagen
Compressive Strength
2014
5
Citations
(Scopus)
127
Downloads
(Pure)
Activation of Akt at T308 and S473 in alcohol, tobacco and HPV-induced HNSCC: is there evidence to support a prognostic or diagnostic role?
Islam, M. R., Ellis, I. R., Macluskey, M., Cochrane, L. & Jones, S. J., 17 Oct 2014, In : Experimental Hematology and Oncology. 3, 9 p., 25.Research output: Contribution to journal › Article
Open Access
File
Tobacco
Alcohols
Phosphorylation
Smoking
Immunohistochemistry
11
Citations
(Scopus)
Is there a pAkt between VEGF and oral cancer cell migration?
Islam, M. R., Jones, S. J., Macluskey, M. & Ellis, I. R., Jun 2014, In : Cellular Signalling. 26, 6, p. 1294-1302 9 p.Research output: Contribution to journal › Article
Mouth Neoplasms
Vascular Endothelial Growth Factor A
Cell Movement
Phosphorylation
Cell Line
2013
The alternate GNB3 splice variant, Gβ3s, exhibits an altered signalling response to EGF stimulation, which leads to enhanced cell migration
Tummala, H., Khalil, H. S., Islam, M. R., Jones, S. J., Ellis, I. R., D'Ascanio, I., Zhelev, N. & Lester, D. H., 30 Nov 2013, In : Biodiscovery. 9, 3, p. 1-22 22 p.Research output: Contribution to journal › Article
Open Access
File
Epidermal Growth Factor
Cell Movement
70-kDa Ribosomal Protein S6 Kinases
Phosphorylation
Phenotype
8
Citations
(Scopus)
The control and importance of hyaluronan synthase expression in palatogenesis
Galloway, J. L., Jones, S. J., Mossey, P. A. & Ellis, I. R., 2013, In : Frontiers in Physiology. 4, 11 p., 10.Research output: Contribution to journal › Article
Hyaluronic Acid
Palate
Extracellular Matrix
Epithelium
Cleft Palate
2012
5
Citations
(Scopus)
Bistable switch in migration stimulating factor expression: regulation by the concerted signalling of transforming growth factor-β1 and the extracellular matrix
Schor, S. L., Ellis, I. R., Jones, S. J., Woolston, A-M. & Schor, A. M., 2012, In : International Journal of Cancer. 130, 9, p. 2024-32 9 p.Research output: Contribution to journal › Article
Transforming Growth Factors
Extracellular Matrix
Fibroblasts
Collagen Type I
Stromal Cells
2011
24
Citations
(Scopus)
Cooperative Binding and Activation of Fibronectin by a Bacterial Surface Protein
Marjenberg, Z. R., Ellis, I. R., Hagan, R. M., Prabhakaran, S., Hoeoek, M., Talay, S. R., Potts, J. R., Staunton, D. & Schwarz-Linek, U., 21 Jan 2011, In : Journal of Biological Chemistry. 286, 3, p. 1884-1894 11 p.Research output: Contribution to journal › Article
4
Citations
(Scopus)
Migration-stimulating factor as a novel biomarker in salivary gland tumours
Aljorani, L. E., Bankfalvi, A., Carey, F. A., Harada, K., Ohe, G., Jones, S. J., Ellis, I. R., Schor, S. L. & Schor, A. M., Nov 2011, In : Journal of Oral Pathology and Medicine. 40, 10, p. 747-754 8 p.Research output: Contribution to journal › Article
VEGF and Oral Cancer - ex Vivo and in Vitro Studies
Islam, M., Alkhadar, H., Paterson, Z., Macluskey, M., Jones, S., Mossey, P. & Ellis, I., Sep 2011, In : European Journal of Cancer. 47, S1, p. S570-S571 2 p., 8593.Research output: Contribution to journal › Book/Film/Article review
2010
Expression of migration stimulating factor in breast tissues and its clinical significance
Schor, A. M., Perrier, S., Woolston, A. M., Jones, S. J., Ellis, I. R., Islam, M. R., Kazmi, S., Purdie, C., Thompson, A. M. & Schor, S. L., 2010, In : Breast Cancer Research. 12, Suppl. 1, 1 p., P37.Research output: Contribution to journal › Book/Film/Article review
7
Citations
(Scopus)
Migration Stimulating Factor (MSF) promotes fibroblast migration by inhibiting AKT
Ellis, I. R., Jones, S. J., Lindsay, Y., Ohe, G., Schor, A. M., Schor, S. L. & Leslie, N. R., Nov 2010, In : Cellular Signalling. 22, 11, p. 1655-1659 5 p.Research output: Contribution to journal › Article
9
Citations
(Scopus)
Multi-factorial modulation of IGD motogenic potential in MSF (Migration Stimulating Factor)
Ellis, I. R., Jones, S. J., Staunton, D., Vakonakis, I., Norman, D. G., Potts, J. R., Milner, C. M., Meenan, N. A. G., Raibaud, S., Ohea, G., Schor, A. M. & Schor, S. L., 10 Sep 2010, In : Experimental Cell Research. 316, 15, p. 2465-2476 12 p.Research output: Contribution to journal › Article
2009
41
Citations
(Scopus)
Motogenic Sites in Human Fibronectin Are Masked by Long Range Interactions
Vakonakis, I., Staunton, D., Ellis, I. R., Sarkies, P., Flanagan, A., Schor, A. M., Schor, S. L. & Campbell, I. D., 5 Jun 2009, In : Journal of Biological Chemistry. 284, 23, p. 15668-15675 8 p.Research output: Contribution to journal › Article
The expression of vascular endothelial growth factor A (VEGFA) and C (VEGFC) and their receptors in head and neck squamous cell carcinoma
Macluskey, M., Jones, S., Stenhouse, G., McLoughlin, P., Ellis, I. & Alkhadar, H., Jul 2009, In : Oral Oncology. p. 212-212 1 p.Research output: Contribution to journal › Book/Film/Article review
1
Citation
(Scopus)
The Oncofetal Paradigm Revisited: MSF and HA as Contextual Drivers of Cancer Progression
Schor, S. L., Schor, A. M., Ellis, I. R., Jones, S. J., Florence, M., Cox, J. & Woolston, A-M., 2009, Hyaluronan in cancer biology. San Diego, CA.: Academic Press, p. 283-306 24 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed)
Hyaluronic Acid
Neoplasms
Angiogenesis Inducing Agents
Pathologic Processes
Stromal Cells
2008
17
Citations
(Scopus)
Differential involvement of TGF-β1 in mediating the motogenic effects of TSP-1 on endothelial cells, fibroblasts and oral tumour cells
Motegi, K., Harada, K., Ohe, G., Jones, S. J., Ellis, I. R., Crouch, D. H., Schor, S. L. & Schor, A. M., 1 Aug 2008, In : Experimental Cell Research. 314, 13, p. 2323-2333 11 p.Research output: Contribution to journal › Article
Identification and role of migration stimulating factor isoforms in breast carcinomas
Schor, A. M., Ellis, I. R., Jones, S. J., Perrier, S., Florence, M. M., Cox, J., Ohe, G., Kankova, K., Vojtesek, B., Thompson, A. M., Purdie, C., Kazmi, S., Foo, S., Woolston, A-M. & Schor, S. L., 2008, In : Breast Cancer Research. 10, Suppl.2, 1 p., P66.Research output: Contribution to journal › Book/Film/Article review
25
Citations
(Scopus)
Individually addressable microelectrode array for monitoring oxygen and nitric oxide release
Patel, B. A., Arundell, M., Quek, R. G. W., Harvey, S. L. R., Ellis, I. R., Florence, M. M., Cass, A. E. G., Schor, A. M. & O'Hare, D., Mar 2008, In : Analytical and Bioanalytical Chemistry. 390, 5, p. 1379-1387 9 p.Research output: Contribution to journal › Article
Migration Stimulating Factor (MSF) as a mediator of Epithelial-Stromal interactions in human tumours
Schor, A. M., Ellis, I. R., Jones, S. J., Perrier, S., Ohe, G. & Schor, S. S., 2008, In : Anticancer Research. 28, 5C, p. 3480-3481 2 p., 602.Research output: Contribution to journal › Book/Film/Article review
2007
9
Citations
(Scopus)
Co-expression by keratinocytes of migration stimulating factor (MSF) and a functional inhibitor of its bioactivity (MSFI)
Jones, S. J., Florence, M. M., Ellis, I. R., Kankova, K., Schor, S. L. & Schor, A. M., 10 Dec 2007, In : Experimental Cell Research. 313, 20, p. 4145-4157 13 p.Research output: Contribution to journal › Article
Keratinocytes
Conditioned Culture Medium
Fibroblasts
Wound Healing
Neoplasms
32
Citations
(Scopus)
EGF AND TGF-α motogenic activities are mediated by the EGF receptor via distinct matrix-dependent mechanisms
Ellis, I. R., Schor, A. M. & Schor, S. L., 15 Feb 2007, In : Experimental Cell Research. 313, 4, p. 732-741 10 p.Research output: Contribution to journal › Article
Epidermal Growth Factor Receptor
Epidermal Growth Factor
Cytokines
CD44 Antigens
70-kDa Ribosomal Protein S6 Kinases
27
Citations
(Scopus)
The role of the fibronectin IGD motif in stimulating fibroblast migration
Millard, C. J., Ellis, I. R., Pickford, A. R., Schor, A. M., Schor, S. L. & Campbell, I. D., 7 Dec 2007, In : Journal of Biological Chemistry. 282, 49, p. 35530-35535 6 p.Research output: Contribution to journal › Article
Fibroblasts
Fibronectins
Protein Isoforms
Nuclear magnetic resonance
Mutation
2006
24
Citations
(Scopus)
A novel “sandwich” assay for quantifying chemo-regulated cell migration within 3-dimensional matrices: Wound healing cytokines exhibit distinct motogenic activities compared to the transmembrane assay
Schor, S. L., Ellis, I. R., Harada, K., Motegi, K., Anderson, S., Chaplain, M. A. J., Keatch, R. P. & Schor, A. M., May 2006, In : Cell Motility and the Cytoskeleton. 63, 5, p. 287-300 14 p.Research output: Contribution to journal › Article
Wound Healing
Cell Movement
Cytokines
Collagen Type I
Transforming Growth Factor beta
Evaluation of migration-stimulating factor expression for breast cancer diagnosis and prognosis
Jones, S. J., Ellis, I. R., Kankova, K., Thompson, A. M., Preece, P., Kazmi, S., Schor, S. L. & Schor, A. M., 2006, In : Breast Cancer Research. 8, Suppl.2, p. S11-S11 1 p., P19.Research output: Contribution to journal › Meeting abstract
2005
5
Citations
(Scopus)
Synthesis of an IGD peptidomimetic with motogenic activity
Shpiro, N., Ellis, I. R., Dines, T. J., Schor, A. M., Schor, S. L., Norman, D. G. & Marquez, R., 2005, In : Molecular BioSystems. 1, 4, p. 318-320 3 p.Research output: Contribution to journal › Article
Peptidomimetics
22
Citations
(Scopus)
The expression of migration stimulating factor, a potent oncofetal cytokine, is uniquely controlled by 3′-untranslated region–dependent nuclear sequestration of its precursor messenger RNA
Kay, R. A., Ellis, I. R., Jones, S. J., Perrier, S., Florence, M. M., Schor, A. M. & Schor, S. L., Dec 2005, In : Cancer Research. 65, 23, p. 10742-10749 8 p.Research output: Contribution to journal › Article
RNA Precursors
Cytokines
Messenger RNA
3' Untranslated Regions
Fibroblasts
2003
83
Citations
(Scopus)
Migration-stimulating factor: a genetically truncated onco-fetal fibronectin isoform expressed by carcinoma and tumor-associated stromal cells
Schor, S. L., Ellis, I. R., Jones, S. J., Baillie, R., Seneviratne, K., Clausen, J., Motegi, K., Vojtesek, B., Kankova, K., Furrie, E., Sales, M. J., Schor, A. M. & Kay, R. A., Dec 2003, In : Cancer Research. 63, 24, p. 8827-8836 10 p.Research output: Contribution to journal › Article
Stromal Cells
Fibronectins
Protein Isoforms
Carcinoma
Complementary DNA
2001
Chemotaxis and Chemokinesis in 3D Macromolecular Matrices: Relevance to Angiogenesis
Schor, A. M., Ellis, I. & Schor, S. L., 2001, Angiogenesis Protocols. Murray, J. C. (ed.). Humana Press, p. 163-83 21 p. (Methods in Molecular Medicine; vol. 46).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Chemotaxis
Pericytes
Fibroblasts
Extracellular Matrix
Blood Vessels
Collagen gel assay for angiogenesis: induction of endothelial cell sprouting
Schor, A. M., Ellis, I. & Schor, S. L., 2001, Angiogenesis Protocols. Murray, J. C. (ed.). Humana Press, p. 145-62 18 p. (Mathods in Molecular Medicine; vol. 46).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Collagen
Endothelial Cells
Gels
Endothelium
Blood Vessels
1999
33
Citations
(Scopus)
Motogenic activity of IGD-containing synthetic peptides
Schor, S. L., Ellis, I., Banyard, J. & Schor, A. M., 1999, In : Journal of Cell Science. 112, 22, p. 3879-88 10 p.Research output: Contribution to journal › Article
Peptides
Fibroblasts
Gelatin
Collagen Type I
Fibronectins
1996
35
Citations
(Scopus)
Substratum-dependent stimulation of fibroblast migration by the gelatin-binding domain of fibronectin
Schor, S. L., Ellis, I., Dolman, C., Banyard, J., Humphries, M. J., Mosher, D. F., Grey, A. M., Mould, A. P., Sottile, J. & Schor, A. M., 1996, In : Journal of Cell Science. 109, 10, p. 2581-90 10 p.Research output: Contribution to journal › Article
Gelatin
Fibronectins
Fibroblasts
Collagen
Collagen Type I
1994
13
Citations
(Scopus)
Fetal-like fibroblasts: their production of migration-stimulating factor and role in tumor progression
Schor, S. L., Grey, A. M., Ellis, I., Schor, A. M., Howell, A., Sloan, P. & Murphy, R., 1994, Mammary Tumorigenesis and Malignant Progression. Dickson, R. B. & Lippman, M. E. (eds.). Boston: Springer US, Vol. 71. p. 277-98 22 p. (Cancer treatment and research).Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed)
1993
13
Citations
(Scopus)
Migration stimulating factor (MSF): its structure, mode of action and possible function in health and disease
Schor, S. L., Grey, A. M., Ellis, I., Schor, A. M., Coles, B. & Murphy, R., 1993, In : Symposia of the Society for Experimental Biology. 47, p. 235-51 17 p.Research output: Contribution to journal › Review article
Fibroblasts
Health
Hyaluronic Acid
Gelatin
Fibronectins
1992
78
Citations
(Scopus)
Antagonistic effects of TGF-beta 1 and MSF on fibroblast migration and hyaluronic acid synthesis: Possible implications for dermal wound healing
Ellis, I., Grey, A. M., Schor, A. M. & Schor, S. L., Jul 1992, In : Journal of Cell Science. 102, 3, p. 447-56 10 p.Research output: Contribution to journal › Article
Transforming Growth Factor beta1
Hyaluronic Acid
Wound Healing
Fibroblasts
Skin
1991
13
Citations
(Scopus)
Heterogeneity amongst fibroblasts in the production of migration stimulating factor (MSF): implications for cancer pathogenesis
Schor, S. L., Grey, A. M., Picardo, M., Schor, A. M., Howell, A., Ellis, I. & Rushton, G., 1991, In : EXS. 59, p. 127-46 20 p.Research output: Contribution to journal › Review article
Fibroblasts
Neoplasms
Hyaluronic Acid
Skin
Hereditary Neoplastic Syndromes
1989
63
Citations
(Scopus)
Mechanism of action of the migration stimulating factor produced by fetal and cancer patient fibroblasts: effect on hyaluronic and synthesis
Schor, S. L., Schor, A. M., Grey, A. M., Chen, J., Rushton, G., Grant, M. E. & Ellis, I., Aug 1989, In : In Vitro Cellular & Developmental Biology - Animal. 25, 8, p. 737-46 10 p.Research output: Contribution to journal › Article
Fibroblasts
Neoplasms
Hyaluronic Acid
Skin Neoplasms
Collagen
124
Citations
(Scopus)
Purification of the migration stimulating factor produced by fetal and breast cancer patient fibroblasts
Grey, A. M., Schor, A. M., Rushton, G., Ellis, I. & Schor, S. L., 1 Apr 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 7, p. 2438-42 5 p.Research output: Contribution to journal › Article
Fibroblasts
Breast Neoplasms
Ammonium Sulfate
Skin
Heparin