Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 4 Quality Education -
SDG 14 Life Below Water
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Collaborations and top research areas from the last five years
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MRC QQR 2024-29
Alessi, D. (Investigator), Davies, P. (Investigator), Ganley, I. (Investigator), Kulathu, Y. (Investigator), Liang, A. (Investigator), Rouse, J. (Investigator), Sapkota, G. (Investigator), Swamy, M. (Investigator), Swatek, K. (Investigator) & Virdee, S. (Investigator)
Project: Research
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Does Mitochondrial Dysfunction Contribute To Diabetes Associated Cognitive Decline
Ganley, I. (Investigator) & McNeilly, A. (Investigator)
1/06/24 → 31/05/25
Project: Research
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Pharmacological Activation of Autography in Vivo - Part 2
Ganley, I. (Investigator)
1/10/22 → 31/10/24
Project: Research
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Determining PINK1 and PRKN Enzyme Activities In Vivo (Joint with University of Nebraska, University of Alabama at Birmingham and Mayo Clinic of Medicine and Science)
Ganley, I. (Investigator)
16/04/21 → 15/12/23
Project: Research
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Determining the ligase and DUB landscape of mitochondrial and alpha-synuclein turnover
Ganley, I. (Investigator), Sapkota, G. (Investigator) & Virdee, S. (Investigator)
1/12/20 → 29/02/24
Project: Research
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AMPK: a master regulator of mitochondrial quality and quantity
Shaw, R. J., Ganley, I. G., Prudent, J. & Hardie, D. G. (Lead / Corresponding author), 12 May 2026, (E-pub ahead of print) In: Trends in Cell Biology.Research output: Contribution to journal › Review article › peer-review
Open AccessFile4 Downloads (Pure) -
AMPK promotes TFEB transcriptional activity through dephosphorylation at both MTORC1-dependent and -independent sites
Negoita, F., Fraguas Bringas, C., Hellberg, K., Luda, K. M., Liu, H., Li, Z., Cuenco, J., Zhao, J. F., Sathe, G., Ganley, I. G., Sapkota, G. P. & Sakamoto, K. (Lead / Corresponding author), 9 Feb 2026, (E-pub ahead of print) In: Autophagy.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)135 Downloads (Pure) -
Author Correction: Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells (Nature Immunology, (2025), 26, 3, (429-443), 10.1038/s41590-025-02090-1)
Sinclair, L. V., Youdale, T., Spinelli, L., Gakovic, M., Langlands, A. J., Pathak, S., Howden, A. J. M., Ganley, I. G. & Cantrell, D. A., 20 Jan 2026, In: Nature Immunology. 27, p. 636 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile16 Downloads (Pure) -
Artificial targeting of autophagy components to mitochondria reveals both conventional and unconventional mitophagy pathways
Lorentzen, K., Prescott, A. & Ganley, I. (Lead / Corresponding author), 2025, In: Autophagy. 21, 2, p. 315-337 23 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Link opens in a new tab Citations (Scopus)196 Downloads (Pure) -
Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells
Sinclair, L. V. (Lead / Corresponding author), Youdale, T., Spinelli, L., Gakovic, M., Langlands, A. J., Pathak, S., Howden, A. J. M., Ganley, I. G. & Cantrell, D. A. (Lead / Corresponding author), 27 Feb 2025, In: Nature Immunology. 26, p. 429-443 32 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Link opens in a new tab Citations (Scopus)73 Downloads (Pure)
Datasets
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Impact of Type II LRRK2 inhibitors on signalling and mitophagy
Tasegian, A. (Creator), Singh, F. (Creator), Ganley, I. G. (Creator), Reith, A. D. (Creator) & Alessi, D. R. (Creator), Zenodo, 13 Sept 2021
DOI: 10.5281/zenodo.5501303, https://zenodo.org/api/records/5501303
Dataset
Prizes
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British Society for Cell Biology Hooke Medal
Ganley, I. (Recipient), 2025
Prize: Prize (including medals and awards)
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Fellow of the Royal Society of Edinburgh
Ganley, I. (Recipient), 24 Mar 2025
Prize: Election to learned society
Activities
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Dundee Research Interest Group Open Doors Day 2026
Alessi, D. (Speaker), Howden, A. (Organiser), Hawdon, B. (Organiser), Bandmann, O. (Speaker), Hardie, G. (Contributor), Caldwell, M. (Speaker), Rigg, D. (Contributor), Donaldson, K. (Contributor), Donaldson, M. (Contributor), Robertson, B. (Contributor), Robertson, H. (Contributor), Sammler, E. (Speaker), Cellan-Jones, R. (Speaker), Milne, J. (Contributor), Flitton, C. (Presenter), Elshani, S. (Presenter), Lis, P. (Presenter), Gomes Moreira, S. (Presenter), Farnaby, W. (Presenter), Kidd, G. (Presenter), Goodburn, J. (Organiser), Hallatt, A. (Presenter), Robertson, J. (Presenter), Urbina Teixidor, A. (Presenter), Tan, Z. Y. (Presenter), Ganley, I. (Presenter), Kiely, M. (Contributor), Muqit, M. (Presenter), de Marcos Lousa, C. (Presenter), Yang, Z. (Presenter), Zeneviciute, K. (Presenter), Langlands, A. (Presenter), Edwards, A. (Contributor), McNeill , C. (Contributor), Clarke, R. (Presenter), Lefter, N. (Presenter), Baker, C. (Presenter), Patrick, S. (Contributor), Hirons, Z. (Advisor), Nash, L. (Contributor), Macmillan, C. (Contributor), Jacobs, L. (Contributor), Munro, D. (Contributor), Nelson, H. (Contributor), Taylor, L. (Contributor), Ellmers, M. (Contributor), Matson, S. (Contributor), Sahu, M. (Presenter), Pratuseviciute, N. (Presenter), Promchai, N. (Presenter) & Fasimoye, R. (Presenter)
27 Jan 2026Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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The North of Scotland Parkinson's Research Podcast Series - Mitophagy
Ganley, I. (Interviewee)
17 Jul 2025Activity: Other activity types › Public engagement and outreach - media article or participation
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Dundee Research Interest Group Open Doors Day 2025
Alessi, D. (Participant), Sammler, E. (Organiser), Howden, A. (Organiser), Muqit, M. (Participant), Ganley, I. (Participant), Gilbertson, T. (Participant), Farnaby, W. (Participant), Hardie, G. (Participant), Hawdon, B. (Organiser), Goodburn, J. (Organiser), Coxe, M. (Participant), Milne, J. (Participant), Rigg, D. (Participant), Vangheluwe, P. (Participant), Kerr, J. (Participant), Stewart, T. (Participant), Lacey-Solymar, G. (Participant), Patrick, S. (Participant), Nash, L. (Participant), Langlands, A. (Participant), Hirons, Z. (Organiser), Grayson, L. (Contributor), Bishnu, A. (Participant), Wilhelm, L. (Participant), Appleton, P. (Participant), Filipe Soares, R. (Participant), Robertson, J. (Participant), Ibba, R. (Participant), Hallatt, A. (Participant) & Wieske, L. (Participant)
28 Feb 2025Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Pint of Science 2025
Atkinson, R. (Organiser), Hein, I. (Speaker), Houston, K. (Speaker), Ganley, I. (Speaker), Li, X. (Speaker), Munro, F. (Speaker), Hall, G. (Speaker) & McSorley, H. (Speaker)
19 May 2025 → 21 May 2025Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Discovery Days 2023
Urch, J. (Organiser), Wasim, S. (Organiser), Preston, E. (Contributor), Gillespie, I. (Chair), Grubb, B. (Chair), Blackford, J. (Speaker), Hannah, B. (Presenter), Kulathu, Y. (Presenter), MacDonald, M. (Presenter), Milner, G. (Presenter), Hartmann, J. (Presenter), Ganley, I. (Presenter), Nanjappa, S. (Presenter), Hoskins, P. (Presenter), Ruda, F. (Presenter), Leslie, D. (Presenter), Schofield, S. (Presenter), Martindale, L. (Presenter), Lushetich, N. (Presenter), Anker, T. (Presenter), Armstrong, V. (Presenter), Armstrong, V. (Presenter), Harrison, E. (Presenter), Kennedy, G. (Presenter), McIntosh, L. (Presenter) & Wasim, S. (Organiser)
11 Jan 2023 → 13 Jan 2023Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar