Gilbert, Ian

Professor

Professor, Biological Chemistry and Drug Discovery

United Kingdom

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7 Not started
11 Active
14 Finished

Target Discovery for Antimalarials (Joint with University of California San Diego)
Gilbert, I.
University of California at San Diego
1/01/21 → 30/06/21
Project: Research
A Platform for Drug Target Deconvolution and Exploitation
Gilbert, I., Horn, D., Pawlowic, M., Wyatt, P. & Wyllie, S.
Wellcome Trust
31/12/20 → 30/12/23
Project: Research
Pilot Study of Aminacyl-Acid tRNA Synthetases as Drug Targets for TB and Malaria
Gilbert, I.
Bill and Melinda Gates Foundation
1/12/20 → 30/11/22
Project: Research
A Drug Target for Shigella (Open Lab Programme)
Gilbert, I., Gray, D. & Read, K.
10/10/19 → 9/10/21
Project: Research
Development of New Agents for the Treatment of Cryptosporidiosis (DPFS) (Joint with University of Vermont)
Gilbert, I., Gray, D., Pawlowic, M., Read, K. & Wyatt, P.
Medical Research Council
1/05/19 → 30/04/22
Project: Research

156 Article
8 Review article
3 Meeting abstract
3 Comment/debate
More
- 3 Patent
- 1 Poster

A scaffold-hopping strategy on a series of proteasome inhibitors which led to a preclinical candidate for the treatment of visceral leishmaniasis
Thomas, M., Brand, S., De Rycker, M., Zuccotto, F., Lukac, I., Dodd, P., Ko, E-J., Manthri, S., McGonagle, K., Osuna-Cabello, M., Riley, J., Pont, C., Simeons, F., Stojanovski, L., Thomas, J., Thompson, S., Viayna, E., Fiandor, J. M., Martín, J., Wyatt, P. G. & 4 others, Miles, T. J., Read, K. D., Marco, M. & Gilbert, I. H., 27 Apr 2021, (E-pub ahead of print) In: Journal of Medicinal Chemistry. 26 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
1 Downloads (Pure)
MalDA, Accelerating Malaria Drug Discovery
Yang, T., Ottilie, S., Istvan, E. S., Godinez-Macias, K. P., Lukens, A. K., Baragaña, B., Campo, B., Walpole, C., Niles, J. C., Chibale, K., Dechering, K. J., Llinás, M., Lee, M. C. S., Kato, N., Wyllie, S., McNamara, C. W., Gamo, F. J., Burrows, J., Fidock, D. A., Goldberg, D. E. & 3 others, Gilbert, I. H., Wirth, D. F. & Winzeler, E. A., 26 Feb 2021, (E-pub ahead of print) In: Trends in Parasitology. 15 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
1 Citation (Scopus)
Multiple unbiased approaches identify oxidosqualene cyclase as the molecular target of a promising anti-leishmanial
S. Paradela, L., Wall, R. J., Carvalho, S., Chemi, G., Corpas-Lopez, V., Moynihan, E., Bello, D., Patterson, S., S. Guther, M. L., Fairlamb, A. H., Ferguson, M. A. J., Zuccotto, F., Martin, J., Gilbert, I. H. & Wyllie, S., 9 Mar 2021, (E-pub ahead of print) In: Cell Chemical Biology. 28, 20 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation
Michalska, K., Jedrzejczak, R., Wower, J., Chang, C., Baragaña, B., Gilbert, I. H., Forte, B. & Joachimiak, A., 22 Apr 2021, (E-pub ahead of print) In: Nucleic Acids Research. 18 p., gkab272.
Research output: Contribution to journal › Article › peer-review

Open Access
File
2 Downloads (Pure)
Plasmodium Kinases as Potential Drug Targets for Malaria: Challenges and Opportunities
Arendse, L. B., Wyllie, S., Chibale, K. & Gilbert, I. H., 12 Mar 2021, In: ACS Infectious Diseases. 7, 3, p. 518-534 17 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
8 Downloads (Pure)

Fellow of the Royal Society of Edinburgh
Muqit, Miratul (Recipient) & Gilbert, Ian (Recipient), 2020
Prize: Election to learned society

1 Participation in conference
1 Public engagement and outreach - media article or participation
1 Public engagement and outreach - public lecture/debate/seminar

In Conversation With... Ian and Kev: Industry, Academia and Drug Discovery
Ali Floyd (Host), Lauren Webster (Chair), Catharine Goddard (Organiser), Andrew Cairns (Organiser), Kevin Read (Interviewee), Ian Gilbert (Interviewee) & Ailsa Mackintosh (Organiser)
27 Jan 2021
Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
The Conversation: New single-dose malaria treatment could eventually help millions
Ian Gilbert (Interviewee)
18 Jun 2015
Activity: Other activity types › Public engagement and outreach - media article or participation
13th International Conference on Antiviral Research
Ian Gilbert (Participant)
17 Apr 2000
Activity: Participating in or organising an event types › Participation in conference

Automated design for Drug Discovery
Andrew L. Hopkins, Suzanne Norval, Jeremy Besnard, Laste Stojanovski, Richard Bickerton, Kevin Read & Ian Gilbert
13/12/12
1 item of Media coverage
Press/Media: Research