1990 …2024
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Fingerprint Dive into the research topics where Ian Gilbert is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 32 Similar Profiles
Trypanosoma brucei brucei Medicine & Life Sciences
Drug Discovery Medicine & Life Sciences
African Trypanosomiasis Medicine & Life Sciences
Parasites Medicine & Life Sciences
Plasmodium falciparum Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Antimalarials Medicine & Life Sciences
Leishmania donovani Medicine & Life Sciences

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Research Output 1990 2019

61 Downloads (Pure)

Characterising Covalent Warhead Reactivity

Martin, J., Mackenzie, C., Fletcher, D. & Gilbert, I., 15 May 2019, In : Bioorganic & Medicinal Chemistry. 27, 10, p. 2066-2074 9 p.

Research output: Contribution to journalArticle

Open Access
File
Toxicity
Pharmaceutical Preparations
Aptitude
Pharmacokinetics
Threonine
3 Citations (Scopus)

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

Thomas, M. G., De Rycker, M., Ajakane, M., Albrecht, S., Álvarez-Pedraglio, A. I., Boesche, M., Brand, S., Campbell, L., Cantizani-Perez, J., Cleghorn, L. A. T., Copley, R. C. B., Crouch, S. D., Daugan, A., Drewes, G., Ferrer, S., Ghidelli-Disse, S., Gonzalez, S., Gresham, S. L., Hill, A. P., Hindley, S. J. & 32 others, Lowe, R. M., MacKenzie, C. J., MacLean, L., Manthri, S., Martin, F., Miguel-Siles, J., Nguyen, V. L., Norval, S., Osuna-Cabello, M., Woodland, A., Patterson, S., Pena, I., Quesada-Campos, M. T., Reid, I. H., Revill, C., Riley, J., Ruiz-Gomez, J. R., Shishikura, Y., Simeons, F. R. C., Smith, A., Smith, V. C., Spinks, D., Stojanovski, L., Thomas, J., Thompson, S., Underwood, T., Gray, D. W., Fiandor, J. M., Gilbert, I. H., Wyatt, P. G., Read, K. D. & Miles, T. J., 14 Feb 2019, In : Journal of Medicinal Chemistry. 62, 3, p. 1180-1202 23 p.

Research output: Contribution to journalArticle

Visceral Leishmaniasis
Leishmania major
Leishmania donovani
Standard of Care
Solubility
19 Downloads (Pure)

Identification of inhibitors of an unconventional Trypanosoma brucei kinetochore kinase

Torrie, L., Zuccotto, F., Robinson, D., Gray, D., Gilbert, I. & De Rycker, M., 31 May 2019, In : PLoS ONE. 14, 5, p. 1-16 16 p., e0217828.

Research output: Contribution to journalArticle

Open Access
File
Kinetochores
Trypanosoma brucei
kinetochores
Trypanosoma brucei brucei
phosphotransferases (kinases)
1 Citation (Scopus)
83 Downloads (Pure)

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Baragaña, B., Forte, B., Choi, R., Nakazawa Hewitt, S., Bueren-Calabuig, J. A., Pisco, J. P., Peet, C., Dranow, D. M., Robinson, D. A., Jansen, C., Norcross, N. R., Vinayak, S., Anderson, M., Brooks, C. F., Cooper, C. A., Damerow, S., Delves, M., Dowers, K., Duffy, J., Edwards, T. E. & 57 others, Hallyburton, I., Horst, B. G., Hulverson, M. A., Ferguson, L., Jiménez-Díaz, M. B., Jumani, R. S., Lorimer, D. D., Love, M. S., Maher, S., Matthews, H., McNamara, C. W., Miller, P., O'Neill, S., Ojo, K. K., Osuna-Cabello, M., Pinto, E., Post, J., Riley, J., Rottmann, M., Sanz, L. M., Scullion, P., Sharma, A., Shepherd, S. M., Shishikura, Y., Simeons, F. R. C., Stebbins, E. E., Stojanovski, L., Straschil, U., Tamaki, F. K., Tamjar, J., Torrie, L. S., Vantaux, A., Witkowski, B., Wittlin, S., Yogavel, M., Zuccotto, F., Angulo-Barturen, I., Sinden, R., Baum, J., Gamo, F-J., Mäser, P., Kyle, D. E., Winzeler, E. A., Myler, P. J., Wyatt, P. G., Floyd, D., Matthews, D., Sharma, A., Striepen, B., Huston, C. D., Gray, D. W., Fairlamb, A. H., Pisliakov, A. V., Walpole, C., Read, K. D., Van Voorhis, W. C. & Gilbert, I. H., 2 Apr 2019, In : Proceedings of the National Academy of Sciences. 116, 14, p. 7015-7020 6 p.

Research output: Contribution to journalArticle

Open Access
File
Lysine-tRNA Ligase
Cryptosporidiosis
Cryptosporidium parvum
Malaria
Plasmodium falciparum
47 Downloads (Pure)

Optimisation of a Key Cross-Coupling Reaction Towards the Synthesis of a Promising Antileishmanial Compound

Velasco, R. F., Guerrero, C., Fra, G., Moure, A., Miguel-Siles, J., Quesada-Campos, M. T., Ruiz-Gomez, J. R., Gilbert, I. H., Thomas, M. G. & Miles, T. J., 2 May 2019, In : Tetrahedron Letters. 60, 18, p. 1243-1247 5 p.

Research output: Contribution to journalArticle

Open Access
File
Sulfonamides
Cross Reactions
Research

Activities 2000 2000

  • 1 Participation in conference

13th International Conference on Antiviral Research

Ian Gilbert (Participant)
17 Apr 2000

Activity: Participating in or organising an event typesParticipation in conference

Press / Media

Automated design for Drug Discovery

Andrew L. Hopkins, Suzanne Norval, Jeremy Besnard, Laste Stojanovski, Richard Bickerton, Kevin Read & Ian Gilbert

13/12/12

1 item of Media coverage

Press/Media: Research

Thesis

Synthetic strategies for potential trypanocides

Author: Capes, A., 2011

Supervisor: Gilbert, I. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Target Identification and Mechanism of Action Studies in Folate Metabolism in Kinetoplastids

Author: Webster, L., 2014

Supervisor: Gilbert, I. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy