Gilbert, Ian

Professor

Professor, Biological Chemistry and Drug Discovery

United Kingdom

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5 Not started
11 Active
12 Finished

A Platform for Drug Target Deconvolution and Exploitation
Gilbert, I., Horn, D., Pawlowic, M., Wyatt, P. & Wyllie, S.
Wellcome Trust
1/05/20 → 30/04/23
Project: Research
A Drug Target for Shigella (Open Lab Programme)
Gilbert, I., Gray, D. & Read, K.
10/10/19 → 9/10/21
Project: Research
Genetic Validation of a Promising Drug Target for Cryptosporidiosis
Baragana, B., Gilbert, I., Pawlowic, M. & Wyllie, S.
Carnegie Trust for the Universities of Scotland
20/08/19 → 19/02/21
Project: Research
Development of New Agents for the Treatment of Cryptosporidiosis (DPFS) (Joint with University of Vermont)
Gilbert, I., Gray, D., Pawlowic, M., Read, K. & Wyatt, P.
Medical Research Council
1/05/19 → 31/12/21
Project: Research
Converting Natural Product Leads into Structure and Ligand Based Drug Discovery Campaigns against Leishmaniasis and Chagas' Disease (Joint with Sao Paulo State University)
Gilbert, I., Read, K. & Wyllie, S.
Medical Research Council
1/04/19 → 31/03/22
Project: Research

152 Article
7 Review article
3 Meeting abstract
3 Comment/debate
3 More
- 2 Patent
- 1 Poster

A platform for target prediction of phenotypic screening hit molecules
Homeyer, N., van Deursen, R., Ochoa-Montaño, B., Heikamp, K., Ray, P., Zuccotto, F., Blundell, T. L. & Gilbert, I. H., Mar 2020, In : Journal of Molecular Graphics & Modelling. 95, p. 1-9 9 p., 107485.
Research output: Contribution to journal › Article › peer-review

Open Access
File
98 Downloads (Pure)
Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease
Harrison, J. R., Sarkar, S., Hampton, S., Riley, J., Stojanovski, L., Sahlberg, C., Appelqvist, P., Erath, J., Mathan, V., Rodriguez, A., Kaiser, M., Pacanowska, D. G., Read, K. D., Johansson, N. G. & Gilbert, I. H., 26 Mar 2020, In : Journal of Medicinal Chemistry. 63, 6, p. 3066-3089 24 p.
Research output: Contribution to journal › Article › peer-review
Discovery of an Allosteric Binding Site in Kinetoplastid Methionyl-tRNA Synthetase
Torrie, L. S., Robinson, D. A., Thomas, M. G., Hobrath, J. V., Shepherd, S. M., Post, J. M., Ko, E. J., Ferreira, R. A., Mackenzie, C. J., Wrobel, K., Edwards, D. P., Gilbert, I. H., Gray, D. W., Fairlamb, A. H. & De Rycker, M., 8 May 2020, In : ACS Infectious Diseases. 6, 5, p. 1044-1057 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
17 Downloads (Pure)
Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity: Initial SAR and Assessment of In Vivo Activity
Thomas, M., De Rycker, M., Wall, R. J., Spinks, D., Epemolu, O., Manthri, S., Norval, S., Osuna-Cabello, M., Patterson, S., Riley, J., Simeons, F. R. C., Stojanovski, L., Thomas, J., Thompson, S., Naylor, C., Fiandor, J. M., Wyatt, P. G., Marco, M., Wyllie, S., Read, K. D. & 2 others, Miles, T. J. & Gilbert, I. H., 10 Sep 2020, In : Journal of Medicinal Chemistry. 63, 17, p. 9523-9539 17 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
16 Downloads (Pure)
Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis
Thomas, M. G., De Rycker, M., Ajakane, M., Crouch, S. D., Campbell, L., Daugan, A., Fra, G., Guerrero, C., Mackenzie, C. J., MacLean, L., Manthri, S., Martin, F., Norval, S., Osuna-Cabello, M., Riley, J., Shishikura, Y., Miguel-Siles, J., Simeons, F. R. C., Stojanovski, L., Thomas, J. & 7 others, Thompson, S., Velasco, R. F., Fiandor, J. M., Wyatt, P. G., Read, K. D., Gilbert, I. H. & Miles, T. J., 21 Oct 2020, In : RSC Medicinal Chemistry. 11, 10, p. 1168-1177 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
19 Downloads (Pure)

Fellow of the Royal Society of Edinburgh
Muqit, Miratul (Recipient) & Gilbert, Ian (Recipient), 2020
Prize: Election to learned society

1 Participation in conference
1 Public engagement and outreach - media article or participation

The Conversation: New single-dose malaria treatment could eventually help millions
Ian Gilbert (Interviewee)
18 Jun 2015
Activity: Other activity types › Public engagement and outreach - media article or participation
13th International Conference on Antiviral Research
Ian Gilbert (Participant)
17 Apr 2000
Activity: Participating in or organising an event types › Participation in conference

Automated design for Drug Discovery
Andrew L. Hopkins, Suzanne Norval, Jeremy Besnard, Laste Stojanovski, Richard Bickerton, Kevin Read & Ian Gilbert
13/12/12
1 item of Media coverage
Press/Media: Research