Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Establishment of Cryo-EM Screening Facility At University Of Dundee (Equipment Grant)
Kulathu, Y. (Investigator), Labib, K. (Investigator), Masson, G. (Investigator), Moraga Gonzalez, I. (Investigator), Murray, D. (Investigator), Owen-Hughes, T. (Investigator), Stanley-Wall, N. (Investigator) & Wyatt, P. (Investigator)
1/12/21 → 31/12/26
Project: Research
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Rapid Research in Covid -19 Programme
Barrable, A. (Investigator), Belch, J. (Investigator), Boehnke, J. (Investigator), Booth, D. (Investigator), Brown, A. (Investigator), Cantrell, D. (Investigator), Chalmers, J. (Investigator), Coleman, S. (Investigator), Connell, D. (Investigator), Cuschieri, A. (Investigator), Dicker, A. (Investigator), Doney, A. (Investigator), Eftimie, R. (Investigator), Fang, M. (Investigator), Farre, A. (Investigator), Gamble, C. (Investigator), Howden, A. (Investigator), Krstajic, N. (Investigator), Lamond, A. (Investigator), Moraga Gonzalez, I. (Investigator), Palmer, C. (Investigator), Parcell, B. (Investigator), Pearson, E. (Investigator), Shoemark, A. (Investigator) & Sixsmith, J. (Investigator)
1/06/20 → 30/09/21
Project: Research
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Mapping Cytokine Signalling Networks using Engineered Surrogate Ligands (ERC Starting Grant)
Crocker, P. (Investigator) & Moraga Gonzalez, I. (Investigator)
COMMISSION OF THE EUROPEAN COMMUNITIES
1/04/17 → 30/09/22
Project: Research
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Mapping Cytokine Signalling Networks using Engineered Surrogate Ligands (Sir Henry Dale Fellowship)
Crocker, P. (Investigator) & Moraga Gonzalez, I. (Investigator)
1/09/16 → 31/08/22
Project: Research
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Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency
Gardner, S., Jin, Y., Fyfe, P. K., Voisin, T. B., Sotolongo Bellón, J., Pohler, E., Piehler, J., Moraga, I. (Lead / Corresponding author) & Bubeck, D. (Lead / Corresponding author), 7 Mar 2024, In: Nature Communications. 15, 11 p., 2071.Research output: Contribution to journal › Article › peer-review
Open AccessFile47 Downloads (Pure) -
Molecular and cellular factors determining the functional pleiotropy of cytokines
McFarlane, A., Pohler, E. & Moraga, I. (Lead / Corresponding author), May 2023, In: FEBS Journal. 290, 10, p. 2525-2552 28 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile9 Citations (Scopus)120 Downloads (Pure) -
IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein
Gaggero, S., Martinez-Fabregas, J., Cozzani, A., Fyfe, P. K., Leprohon, M., Yang, J., Thomasen, F. E., Winkelmann, H., Magnez, R., Conti, A. G., Wilmes, S., Pohler, E., van Gijsel Bonnello, M., Thuru, X., Quesnel, B., Soncin, F., Piehler, J., Lindorff-Larsen, K., Roychoudhuri, R. (Lead / Corresponding author) & Moraga, I. (Lead / Corresponding author) & 1 others, , 2 Dec 2022, In: Science Immunology. 7, 78, 15 p., eade568.Research output: Contribution to journal › Article › peer-review
Open AccessFile38 Citations (Scopus)723 Downloads (Pure) -
Structural insights into the assembly and activation of the IL-27 signaling complex
Jin, Y., Fyfe, P. K., Gardner, S., Wilmes, S., Bubeck, D. (Lead / Corresponding author) & Moraga, I. (Lead / Corresponding author), 6 Oct 2022, In: EMBO Reports. 23, 10, 10 p., e55450.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)156 Downloads (Pure) -
Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses
Wilmes, S., Jeffrey, P.-A., Martinez-Fabregas, J., Hafer, M., Fyfe, P. K., Pohler, E., Gaggero, S., Lopez-Garcia, M., Lythe, G., Taylor, C., Guerrier, T., Launay, D., Mitra, S., Piehler, J., Molina-Paris, C. (Lead / Corresponding author) & Moraga Gonzalez, I. (Lead / Corresponding author), 5 May 2021, In: eLife. 10, 44 p., e66014.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)166 Downloads (Pure)
Activities
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9th Annual Meeting of the International Cytokine & Interferon Society, Cardiff, UK
Moraga Gonzalez, I. (Participant)
2021Activity: Participating in or organising an event types › Participation in conference
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5th French International symposium « CAR T Day», Lille, France
Moraga Gonzalez, I. (Participant)
2021Activity: Participating in or organising an event types › Participation in conference
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Incredible Immunology
Moraga Gonzalez, I. (Member)
8 May 2015Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar