Projects per year
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Dive into the research topics where Ignacio Moraga Gonzalez is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
- 3 Active
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Rapid Research in Covid -19 Programme
Barrable, A., Belch, J., Boehnke, J., Booth, D., Brown, A., Cantrell, D., Chalmers, J., Coleman, S., Connell, D., Cuschieri, A., Dicker, A., Doney, A., Eftimie, R., Fang, M., Farre, A., Gamble, C., Howden, A., Krstajic, N., Lamond, A., Moraga Gonzalez, I., Palmer, C., Parcell, B., Pearson, E., Shoemark, A. & Sixsmith, J.
1/06/20 → 28/02/21
Project: Research
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Mapping Cytokine Signalling Networks using Engineered Surrogate Ligands (Sir Henry Dale Fellowship)
Crocker, P. & Moraga Gonzalez, I.
1/09/16 → 28/02/22
Project: Research
Research Output
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Engineered IL-10 variants elicit potent immunomodulatory effects at low ligand doses
Gorby, C., Sotolongo Bellón, J., Wilmes, S., Warda, W., Pohler, E., Fyfe, P. K., Cozzani, A., Ferrand, C., Walter, M. R., Mitra, S., Piehler, J. & Moraga, I., 15 Sep 2020, In : Science Signaling. 13, 649, 19 p., eabc0653.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations
Wilmes, S., Hafer, M., Vuorio, J., Tucker, J. A., Winkelmann, H., Löchte, S., Stanly, T. A., Pulgar Prieto, K. D., Poojari, C., Sharma, V., Richter, C. P., Kurre, R., Hubbard, S. R., Garcia, K. C., Moraga, I., Vattulainen, I., Hitchcock, I. S. & Piehler, J., 7 Feb 2020, In : Science. 367, 6478, p. 643-652 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)8 Downloads (Pure) -
Kinetics of cytokine receptor trafficking determine signaling and functional selectivity
Martinez-Fabregas, J., Wilmes, S., Wang, L., Hafer, M., Pohler, E., Lokau, J., Garbers, C., Cozzani, A., Piehler, J., Kazemian, M., Mitra, S. & Moraga Gonzalez, I., 27 Nov 2019, In : eLife. 8, p. 1-32 32 p., e49314.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)68 Downloads (Pure) -
Loss of Adenomatous polyposis coli function renders intestinal epithelial cells resistant to the cytokine IL-22
Chen, Y., Vandereyken, M., Newton, I., Moraga Gonzalez, I., Nathke, I. & Swamy, M., 26 Nov 2019, In : PLoS Biology. 17, 11, p. 1-23 23 p., e3000540.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)70 Downloads (Pure) -
Mapping determinants of cytokine signaling via protein engineering
Gorby, C., Martinez-Fabregas, J., Wilmes, S. & Moraga Gonzalez, I., 27 Sep 2018, In : Frontiers in Immunology. 9, 9 p., 2143.Research output: Contribution to journal › Review article › peer-review
Open AccessFile2 Citations (Scopus)162 Downloads (Pure)