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Moraga Gonzalez, Ignacio


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  • 13 Similar Profiles
Cytokine Receptors Medicine & Life Sciences
Cytokines Medicine & Life Sciences
Ligands Medicine & Life Sciences
Dimers Chemical Compounds
Protein Engineering Medicine & Life Sciences
Adenomatous Polyposis Coli Medicine & Life Sciences
Interleukins Medicine & Life Sciences
interleukins Agriculture & Biology

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Projects 2016 2022

Research Output 2017 2019

Kinetics of cytokine receptor trafficking determine signaling and functional selectivity

Martinez-Fabregas, J., Wilmes, S., Wang, L., Hafer, M., Pohler, E., Lokau, J., Garbers, C., Cozzani, A., Piehler, J., Kazemian, M., Mitra, S. & Moraga Gonzalez, I., 27 Nov 2019, In : eLife.

Research output: Contribution to journalArticle

Open Access
Cytokine Receptors
Th17 Cells

Loss of Adenomatous polyposis coli function renders intestinal epithelial cells resistant to the cytokine IL-22

Chen, Y., Vandereyken, M., Newton, I., Moraga Gonzalez, I., Nathke, I. & Swamy, M., 26 Nov 2019, In : PLoS Biology. 17, 11, 23 p., e3000540.

Research output: Contribution to journalArticle

Open Access
Adenomatous Polyposis Coli
epithelial cells
Epithelial Cells
95 Downloads (Pure)

Mapping determinants of cytokine signaling via protein engineering

Gorby, C., Martinez-Fabregas, J., Wilmes, S. & Moraga Gonzalez, I., 27 Sep 2018, In : Frontiers in Immunology. 9, 9 p., 2143.

Research output: Contribution to journalReview article

Open Access
Protein Engineering
Janus Kinases
Cytokine Receptors
12 Citations (Scopus)
77 Downloads (Pure)

Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimers

Moraga, I., Spangler, J. B., Mendoza, J. L., Gakovic, M., Wehrman, T. S., Krutzik, P. & Garcia, K. C., 12 May 2017, In : eLife. 6, e22882.

Research output: Contribution to journalArticle

Open Access
Intercellular Signaling Peptides and Proteins
Cytokine Receptors