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Moraga Gonzalez, Ignacio

Dr

20162020

Research output per year

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Projects

Research Output

Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations

Wilmes, S., Hafer, M., Vuorio, J., Tucker, J. A., Winkelmann, H., Löchte, S., Stanly, T. A., Pulgar Prieto, K. D., Poojari, C., Sharma, V., Richter, C. P., Kurre, R., Hubbard, S. R., Garcia, K. C., Moraga, I., Vattulainen, I., Hitchcock, I. S. & Piehler, J., 7 Feb 2020, In : Science. 367, 6478, p. 643-652 10 p.

Research output: Contribution to journalArticle

  • 3 Citations (Scopus)

    Kinetics of cytokine receptor trafficking determine signaling and functional selectivity

    Martinez-Fabregas, J., Wilmes, S., Wang, L., Hafer, M., Pohler, E., Lokau, J., Garbers, C., Cozzani, A., Piehler, J., Kazemian, M., Mitra, S. & Moraga Gonzalez, I., 27 Nov 2019, In : eLife. 8, p. 1-32 32 p., e49314.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 40 Downloads (Pure)

    Loss of Adenomatous polyposis coli function renders intestinal epithelial cells resistant to the cytokine IL-22

    Chen, Y., Vandereyken, M., Newton, I., Moraga Gonzalez, I., Nathke, I. & Swamy, M., 26 Nov 2019, In : PLoS Biology. 17, 11, p. 1-23 23 p., e3000540.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 1 Citation (Scopus)
    53 Downloads (Pure)

    Mapping determinants of cytokine signaling via protein engineering

    Gorby, C., Martinez-Fabregas, J., Wilmes, S. & Moraga Gonzalez, I., 27 Sep 2018, In : Frontiers in Immunology. 9, 9 p., 2143.

    Research output: Contribution to journalReview article

    Open Access
    File
  • 144 Downloads (Pure)

    Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimers

    Moraga, I., Spangler, J. B., Mendoza, J. L., Gakovic, M., Wehrman, T. S., Krutzik, P. & Garcia, K. C., 12 May 2017, In : eLife. 6, e22882.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 13 Citations (Scopus)
    129 Downloads (Pure)