Leigh, Irene

Professor

  • 6201 Citations
  • 32 h-Index
1989 …2020

Research output per year

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2020

The Identification of Potential Therapeutic Targets for Cutaneous Squamous Cell Carcinoma

McHugh, A., Fernandes, K., Chinner, N., Ibrahim, A. F. M., Garg, A. K., Boag, G., Hepburn, L. A., Proby, C. M., Leigh, I. M. & Saville, M. K., Jun 2020, In : Journal of Investigative Dermatology. 140, 6, p. 1154-1165.e5 17 p.

Research output: Contribution to journalArticle

Open Access
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65 Downloads (Pure)
2019

A Unique Panel of Patient-Derived Cutaneous Squamous Cell Carcinoma Cell Lines Provides a Preclinical Pathway for Therapeutic Testing

Hassan, S., Purdie, K. J., Wang, J., Harwood, C. A., Proby, C. M., Pourreyron, C., Mladkova, N., Nagano, A., Dhayade, S., Athineos, D., Caley, M., Mannella, V., Blyth, K., Inman, G. J. & Leigh, I. M., 12 Jul 2019, In : International Journal of Molecular Sciences. 20, 14, p. 1-26 26 p., 3428.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
82 Downloads (Pure)

Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model

Kalin, J. H., Eroglu, A., Liu, H., Holtzclaw, W. D., Leigh, I., Proby, C. M., Fahey, J. W., Cole, P. A. & Dinkova-Kostova, A. T., 13 Mar 2019, In : PLoS ONE. 14, 3, p. 1-13 13 p., e0213095.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
110 Downloads (Pure)
2018

Nationwide Incidence of Metastatic Cutaneous Squamous Cell Carcinoma in England

Venables, Z. C., Autier, P., Nijsten, T., Wong, K. F., Langan, S. M., Rous, B., Broggio, J., Harwood, C., Henson, K., Proby, C. M., Rashbass, J. & Leigh, I. M., 28 Nov 2018, In : JAMA Dermatology. 153, 3, p. 298-306 9 p.

Research output: Contribution to journalArticle

Open Access
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17 Citations (Scopus)
191 Downloads (Pure)

Preclinical comparison of proteasome and ubiquitin E1 enzyme inhibitors in cutaneous squamous cell carcinoma: the identification of mechanisms of differential sensitivity

McHugh, A., Fernandes, K., South, A., Mellerio, J. E., Salas-Alanis, J. C., Proby, C., Leigh, I. & Saville, M., 17 Apr 2018, In : Oncotarget. 9, p. 20265-20281 17 p.

Research output: Contribution to journalArticle

Open Access
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6 Citations (Scopus)
147 Downloads (Pure)

Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma

Rose, A. M., Spender, L. C., Stephen, C., Mitchell, A., Rickaby, W., Bray, S., Evans, A. T., Dayal, J., Purdie, K. J., Harwood, C. A., Proby, C. M., Leigh, I. M., Coates, P. J. . & Inman, G. J., 6 Mar 2018, In : Oncotarget. 9, 18, p. 14552-14566 15 p.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
184 Downloads (Pure)

Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity

Hepburn, L., McHugh, A., Fernandes, K., Boag, G., Proby, C., Leigh, I. & Saville, M., 1 May 2018, In : Oncotarget. 9, 33, p. 23029-23046 18 p.

Research output: Contribution to journalArticle

Open Access
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8 Citations (Scopus)
126 Downloads (Pure)

The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature

Inman, G. J., Wang, J., Nagano, A., Alexandrov, L. B., Purdie, K. J., Taylor, R. G., Sherwood, V., Thomson, J., Hogan, S., Spender, L. C., South, A. P., Stratton, M., Chelala, C., Harwood, C. A., Proby, C. M. & Leigh, I. M., 10 Sep 2018, In : Nature Communications. 9, 1, p. 1-14 14 p., 3667.

Research output: Contribution to journalArticle

Open Access
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37 Citations (Scopus)
144 Downloads (Pure)

The Role of Human Papillomaviruses and Polyomaviruses in BRAF-Inhibitor Induced Cutaneous Squamous Cell Carcinoma and Benign Squamoproliferative Lesions

Purdie, K. J., Proby, C. M., Rizvi, H., Griffin, H., Doorbar, J., Sommerlad, M., Feltkamp, M. C., Van der Meijden, E., Inman, G. J., South, A. P., Leigh, I. M. & Harwood, C. A., 14 Aug 2018, In : Frontiers in Microbiology. 9, 16 p., 1806.

Research output: Contribution to journalArticle

Open Access
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6 Citations (Scopus)
133 Downloads (Pure)
2017

Genomic analysis of atypical fibroxanthoma

Lai, K., Harwood, C. A., Purdie, K. J., Proby, C. M., Leigh, I. M., Ravi, N., Mully, T. W., Brooks, L., Sandoval, P. M., Rosenblum, M. D. & Arron, S. T., 15 Nov 2017, In : PLoS ONE. 12, 11, p. 1-15 15 p., e0188272.

Research output: Contribution to journalArticle

Open Access
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9 Citations (Scopus)
221 Downloads (Pure)

Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16

Maruthappu, T., Chikh, A., Fell, B., Delaney, P. J., Brooke, M. A., Levet, C., Moncada-Pazos, A., Ishida-Yamamoto, A., Blaydon, D., Waseem, A., Leigh, I. M., Freeman, M. & Kelsell, D. P., 27 Jan 2017, In : Nature Communications. 8, p. 1-11 11 p., 14174.

Research output: Contribution to journalArticle

Open Access
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13 Citations (Scopus)
164 Downloads (Pure)
2016

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

Cammareri, P., Rose, A., Vincent, D. F., Wang, J., Nagano, A., Libertini, S., Ridgway, R. A., Athineos, D., Coates, P. J. ., McHugh, A., Pourreyron, C., Dayal, J., Larsson, J., Weidlich, S., Spender, L., Sapkota, G., Purdie, K. J., Proby, C., Harwood, C. A., Leigh, I. & 9 others, Clevers, H., Barker, N., Karlsson, S., Pritchard, C., Marais, R., Chelala, C., South, A., Sansom, O. J. & Inman, G., 25 Aug 2016, In : Nature Communications. 7, p. 1-7 7 p., 12493.

Research output: Contribution to journalArticle

Open Access
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43 Citations (Scopus)
127 Downloads (Pure)
2015

Lysyl hydroxylase 3 localizes to epidermal basement membrane and Is reduced in patients with Recessive Dystrophic Epidermolysis Bullosa

Watt, S. A., Dayal, J. H. S., Wright, S., Riddle, M., Pourreyron, C., McMillan, J. R., Kimble, R. M., Prisco, M., Gartner, U., Warbrick, E., McLean, W. H. I., Leigh, I. M., McGrath, J. A., Salas-Alanis, J. C., Tolar, J. & South, A. P., 18 Sep 2015, In : PLoS ONE. 10, 9, 15 p., e0137639.

Research output: Contribution to journalArticle

Open Access
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12 Citations (Scopus)
178 Downloads (Pure)

Novel CARD11 mutations in human cutaneous squamous cell carcinoma lead to aberrant NF-κB regulation

Watt, S. A., Purdie, K. J., den Breems, N. Y., Dimon, M., Arron, S. T., McHugh, A. T., Xue, D. J., Dayal, J. H. S., Proby, C. M., Harwood, C. A., Leigh, I. M. & South, A. P., Sep 2015, In : American Journal of Pathology. 185, 9, p. 2354-2363 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2014

High levels of type VII collagen expression in RDEB cSCC keratinocytes increases PI3K and MAPK signalling, cell migration and invasion

Pourreyron, C., Chen, M., McGrath, J. A., Salas-Alanis, J. C., South, A. P. & Leigh, I. M., 2014, In : British Journal of Dermatology. 170, 6, p. 1256-1265 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Inherited epidermolysis bullosa: updated recommendations on diagnosis and classification

Fine, J-D., Bruckner-Tuderman, L., Eady, R. A. J., Bauer, E. A., Bauer, J. W., Has, C., Heagerty, A., Hintner, H., Hovnanian, A., Jonkman, M. F., Leigh, I., Marinkovich, M. P., Martinez, A. E., McGrath, J. A., Mellerio, J. E., Moss, C., Murrell, D. F., Shimizu, H., Uitto, J., Woodley, D. & 1 others, Zambruno, G., Jun 2014, In : Journal of the American Academy of Dermatology. 70, 6, p. 1103-1126 24 p.

Research output: Contribution to journalArticle

449 Citations (Scopus)

NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis

South, A. P., Purdie, K. J., Watt, S. A., Haldenby, S., den Breems, N., Dimon, M., Arron, S. T., Kluk, M. J., Aster, J. C., McHugh, A., Xue, D. J., Dayal, J. H. S., Robinson, K. S., Rizvi, S. M. H., Proby, C. M., Harwood, C. A. & Leigh, I. M., Oct 2014, In : Journal of Investigative Dermatology. 134, 10, p. 2630-2638 9 p.

Research output: Contribution to journalArticle

142 Citations (Scopus)

Type VII collagen regulates expression of OATP1B3, promotes front-to-rear polarity and increases structural organisation in 3D spheroid cultures of RDEB tumour keratinocytes

Dayal, J. H. S., Cole, C. L., Pourreyron, C., Watt, S. A., Lim, Y. Z., Salas-Alanis, J. C., Murrell, D. F., McGrath, J. A., Stieger, B., Jahoda, C., Leigh, I. M. & South, A. P., 15 Feb 2014, In : Journal of Cell Science. 127, 4, p. 740-751 12 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2013

A surveillance model for skin cancer in organ transplant recipients: A 22-year prospective study in an ethnically diverse population

Harwood, C. A., Mesher, D., McGregor, J. M., Mitchell, L., Leedham-Green, M., Raftery, M., Cerio, R., Leigh, I. M., Sasieni, P. & Proby, C. M., Jan 2013, In : American Journal of Transplantation. 13, 1, p. 119-129 11 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

Gauging NOTCH1 activation in cancer using immunohistochemistry

Kluk, M. J., Ashworth, T., Wang, H., Knoechel, B., Mason, E. F., Morgan, E. A., Dorfman, D., Pinkus, G., Weigert, O., Hornick, J. L., Chirieac, L. R., Hirsch, M., Oh, D. J., South, A. P., Leigh, I. M., Pourreyron, C., Cassidy, A. J., DeAngelo, D. J., Weinstock, D. M., Krop, I. E. & 10 others, Dillon, D., Brock, J. E., Lazar, A. J. F., Peto, M., Cho, R. J., Stoeck, A., Haines, B. B., Sathayanrayanan, S., Rodig, S. & Aster, J. C., 2013, In : PLoS ONE. 8, 6, 14 p., e67306.

Research output: Contribution to journalArticle

66 Citations (Scopus)

Key differences identified between actinic keratosis and cutaneous squamous cell carcinoma by transcriptome profiling

Lambert, S. R., Mladkova, N., Gulati, A., Hamoudi, R., Purdie, K., Cerio, R., Leigh, I., Proby, C. & Harwood, C. A., 21 Jan 2013, In : British Journal of Cancer. 110, 2, p. 520-529 10 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Methylated tissue factor pathway inhibitor 2 (TFPI2) DNA in serum is a biomarker of metastatic melanoma

Nigro, C. L., Wang, H., McHugh, A., Lattanzio, L., Matin, R., Harwood, C., Syed, N., Hatzimichael, E., Briasoulis, E., Merlano, M., Evans, A., Thompson, A., Leigh, I., Fleming, C., Inman, G. J., Proby, C. & Crook, T., May 2013, In : Journal of Investigative Dermatology. 133, 5, p. 1278-1285 8 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Mutations in AQP5, encoding a water-channel protein, cause autosomal-dominant diffuse nonepidermolytic palmoplantar keratoderma

Blaydon, D. C., Lind, L. K., Plagnol, V., Linton, K. J., Smith, F. J. D., Wilson, N. J., McLean, W. H. I., Munro, C. S., South, A. P., Leigh, I. M., O'Toole, E. A., Lundström, A. & Kelsell, D. P., 8 Aug 2013, In : American Journal of Human Genetics. 93, 2, p. 330-335 6 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)
2012

A quantitative molecular diagnostic system for predicting progression of vulval intraepithelial neoplasia to invasive squamous cell carcinoma

Purdie, K., Gibbon, K., Proby, C., Leigh, I., Harwood, C. & Teh, T., Apr 2012, In : British Journal of Dermatology. 166, 4, p. e29-e29 1 p., P-1.

Research output: Contribution to journalArticle

37 Citations (Scopus)

ARNT controls the expression of epidermal differentiation genes through HDAC- and EGFR-dependent pathways

Robertson, E. D., Weir, L., Romanowska, M., Leigh, I. M. & Panteleyev, A. A., 15 Jul 2012, In : Journal of Cell Science. 125, 14, p. 3320-3332 13 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Dermal matrix composition promotes development of aggressive squamous cell carcinoma in recessive dystrophic epidermolysis bullosa

Ng, Y., Pourreyron, C., Salas-Alanis, J., Cepeda-Valdes, R., Yan, W., Wright, S., Chen, M., Hogg, F., McGrath, J., Murrell, D., Leigh, I., Lane, E. & South, A., May 2012, In : Journal of Investigative Dermatology. 132, p. S20-S20 1 p.

Research output: Contribution to journalArticle

Fibroblast-derived dermal matrix drives development of aggressive cutaneous squamous cell carcinoma in patients with recessive dystrophic epidermolysis bullosa

Ng, Y-Z., Pourreyron, C., Salas-Alanis, J. C., Dayal, J. H. S., Cepeda-Valdes, R., Yan, W., Wright, S., Chen, M., Fine, J-D., Hogg, F. J., McGrath, J. A., Murrell, D. F., Leigh, I. M., Lane, E. B. & South, A. P., 2012, In : Cancer Research. 72, 14, p. 3522-3534 13 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Metastatic cutaneous squamous cell carcinoma shows frequent deletion in the protein tyrosine phosphatase receptor Type D gene

Lambert, S. R., Harwood, C. A., Purdie, K. J., Gulati, A., Matin, R. N., Romanowska, M., Cerio, R., Kelsell, D. P., Leigh, I. M. & Proby, C. M., 2012, In : International Journal of Cancer. 131, 3, p. E216-E226

Research output: Contribution to journalArticle

12 Citations (Scopus)

Next-generation sequencing identifies Notch receptors as integral tumor suppressors in cutaneous and lung squamous cell carcinomas

Wang, N. J., Sanborn, Z., Arnett, K. L., Bayston, L. J., Liao, W., Proby, C. M., Leigh, I. M., Gordon, P. B., Sharma, M., North, J. P., Vemula, S. S., Mauro, T. M., Neuhaus, I. M., LeBoit, P. E., Kwok, P., Arron, S. T., Bale, A. E., Haussler, D., Cleaver, J. E., Gray, J. W. & 5 others, Spellman, P. T., South, A. P., Aster, J. C., Blacklow, S. C. & Cho, R. J., May 2012, In : Journal of Investigative Dermatology. 132, p. S23-S23 1 p.

Research output: Contribution to journalArticle

NT5E (CD73) is epigenetically regulated in malignant melanoma and associated with metastatic site specificity

Wang, H., Lee, S., Lo Nigro, C., Lattanzio, L., Merlano, M., Monteverde, M., Matin, R., Purdie, K., Mladkova, N., Bergamaschi, D., Harwood, C., Syed, N., Szlosarek, P., Briasoulis, E., McHugh, A., Thompson, A., Evans, A., Leigh, I., Fleming, C., Inman, G. J. & 3 others, Hatzimichael, E., Proby, C. & Crook, T., 2012, In : British Journal of Cancer. 106, 8, p. 1446-52 7 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

RHBDF2 Mutations Are Associated with Tylosis, a Familial Esophageal Cancer Syndrome

Blaydon, D. C., Etheridge, S. L., Risk, J. M., Hennies, H-C., Gay, L. J., Carroll, R., Plagnol, V., McRonald, F. E., Stevens, H. P., Spurr, N. K., Bishop, D. T., Ellis, A., Jankowski, J., Field, J. K., Leigh, I. M., South, A. P. & Kelsell, D. P., 10 Feb 2012, In : American Journal of Human Genetics. 90, 2, p. 340-346 7 p.

Research output: Contribution to journalArticle

108 Citations (Scopus)

RNAi depletion of PRSS21 induces apoptosis in cutaneous squamous cell carcinoma keratinocytes

Robinson, K., Watt, S., Leigh, I. & South, A., Apr 2012, In : British Journal of Dermatology. 166, 4, p. e25-e25 1 p., O-25.

Research output: Contribution to journalArticle

The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro

Cheung, B. B., Koach, J., Tan, O., Kim, P., Bell, J. L., D'andreti, C., Sutton, S., Malyukova, A., Sekyere, E., Norris, M., Haber, M., Kavallaris, M., Cunningham, A. M., Proby, C., Leigh, I., Wilmott, J. S., Cooper, C. L., Halliday, G. M., Scolyer, R. A. & Marshall, G. M., Feb 2012, In : Journal of Pathology. 226, 3, p. 451-462 12 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Two mechanisms regulate keratin K15 expression in keratinocytes: role of PKC/AP-1 and FOXM1 mediated signalling

Bose, A., Teh, M-T., Hutchison, I. L., Wan, H., Leigh, I. M. & Waseem, A., 2012, In : PLoS ONE. 7, 6, e38599.

Research output: Contribution to journalArticle

22 Citations (Scopus)
12 Citations (Scopus)

Wnt5a inhibits the CpG oligodeoxynucleotide-triggered activation of human plasmacytoid dendritic cells

Hack, K., Reilly, L., Proby, C., Fleming, C., Leigh, I. & Foerster, J., Apr 2012, In : British Journal of Dermatology. 166, 4, p. e36-e36 1 p., P-24.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2011

Cutaneous Squamous Cell Carcinoma (SCC) and the DNA Damage Response: pATM Expression Patterns in Pre-Malignant and Malignant Keratinocyte Skin Lesions

Ismail, F., Ikram, M., Purdie, K., Harwood, C., Leigh, I. & Storey, A., 1 Jul 2011, In : PLoS ONE. 6, 7, p. - 14 p., e21271.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Hypoxia-mediated control of HIF/ARNT machinery in epidermal keratinocytes

Weir, L., Robertson, D., Leigh, I. M., Vass, J. K. & Panteleyev, A. A., Jan 2011, In : Biochimica et Biophysica Acta. Molecular Cell Research. 1813, 1, p. 60-72 13 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma

Watt, S., Pourreyron, C., Purdie, K., Hogan, C., Cole, C. L., Foster, N., Pratt, N., Bourdon, J-C., Appleyard, V., Murray, K., Thompson, A., Mao, X., Mein, C., Bruckner-Tuderman, L., Evans, A., McGrath, J. A., Proby, C. M., Foerster, J., Leigh, I. & South, A., Nov 2011, In : Oncogene. 30, 46, p. 4666-4677 12 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Keratin 14-Null Cells as a Model to Test the Efficacy of Gene Therapy Approaches in Epithelial Cells

D'Alessandro, M., Coats, S. E., Jonkmann, M. F., Leigh, I. M. & Lane, B., Jul 2011, In : Journal of Investigative Dermatology. 131, 7, p. 1412-1419 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

Wang, N. J., Sanborn, Z., Arnett, K. L., Bayston, L. J., Liao, W., Proby, C. M., Leigh, I. M., Collisson, E. A., Gordon, P. B., Jakkula, L., Pennypacker, S., Zou, Y., Sharma, M., North, J. P., Vemula, S. S., Mauro, T. M., Neuhaus, I. M., LeBoit, P. E., Hur, J. S., Park, K. & 13 others, Huh, N., Kwok, P-Y., Arron, S. T., Massion, P. P., Bale, A. E., Haussler, D., Cleaver, J. E., Gray, J. W., Spellman, P. T., South, A. P., Aster, J. C., Blacklow, S. C. & Cho, R. J., 25 Oct 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 43, p. 17761-17766 6 p.

Research output: Contribution to journalArticle

259 Citations (Scopus)

The reduction of water-soluble tetrazolium salt reagent on the plasma membrane of epidermal keratinocytes is oxygen dependent

Weir, L., Robertson, D., Leigh, I. M. & Panteleyev, A. A., 1 Jul 2011, In : Analytical Biochemistry. 414, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2010

High-resolution genomic profiling of human papillomavirus-associated vulval neoplasia

Purdie, K. J., Harwood, C. A., Gibbon, K., Chaplin, T., Young, B. D., Cazier, J. B., Singh, N., Leigh, I. M. & Proby, C. M., 16 Mar 2010, In : British Journal of Cancer. 102, 6, p. 1044-1051 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Revised nomenclature and classification of inherited ichthyoses: Results of the First Ichthyosis Consensus Conference in Sorze 2009

Oji, V., Tadini, G., Akiyama, M., Blanchet Bardon, C., Bodemer, C., Bourrat, E., Coudiere, P., Digiovanna, J. J., Elias, P., Fischer, J., Fleckman, P., Gina, M., Harper, J., Hashimoto, T., Hausser, I., Hennies, H. C., Hohl, D., Hovnanian, A., Ishida-Yamamoto, A., Jacyk, W. K. & 17 others, Leachman, S., Leigh, I., Mazereeuw-Hautier, J., Milstone, L., Morice-Picard, F., Paller, A. S., Richard, G., Schmuth, M., Shimizu, H., Sprecher, E., van Steensel, M., Taïeb, A., Toro, J. R., Vabres, P., Vahlquist, A., Williams, M. & Traupe, H., 2010, In : Journal of the American Academy of Dermatology. 63, 4, p. 607-641 35 p.

Research output: Contribution to journalArticle

400 Citations (Scopus)

Tyrosine dephosphorylation is required for Bak activation in apoptosis

Fox, J. L., Ismail, F., Azad, A., Ternette, N., Leverrier, S., Edelmann, M. J., Kessler, B. M., Leigh, I. M., Jackson, S. & Storey, A., 17 Nov 2010, In : EMBO Journal. 29, 22, p. 3853-3868 16 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2009

Single Nucleotide Polymorphism Array Analysis Defines a Specific Genetic Fingerprint for Well-Differentiated Cutaneous SCCs

Purdie, K. J., Harwood, C. A., Gulati, A., Chaplin, T., Lambert, S. R., Cerio, R., Kelly, G. P., Cazier, J-B., Young, B. D., Leigh, I. M. & Proby, C. M., Jun 2009, In : Journal of Investigative Dermatology. 129, 6, p. 1562-1568 7 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2008

An altered keratinocyte phenotype in oral submucous fibrosis: Correlation of keratin K17 expression with disease severity

Lalli, A., Tilakaratne, W. M., Ariyawardana, A., Fitchett, C., Leigh, I. M., Hagi-Pavli, E., Cruchley, A. T., Parkinson, E. K., Teh, M-T., Fortune, F. & Waseem, A., 2008, In : Journal of Oral Pathology and Medicine. 37, 4, p. 211-220 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Clinical application of skin substitutes

Damodaran, G., Syed, M., Leigh, I., Myers, S. & Navsaria, H., 2008, In : Expert Review of Dermatology. 3, 3, p. 345-356 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Development of a treatment algorithm for actinic keratoses: a European Consensus

Stockfleth, E., Ferrandiz, C., Grob, J. J., Leigh, I., Pehamberger, H., Kerl, H. & European Skin Acad, 2008, In : European Journal of Dermatology. 18, 6, p. 651-659 9 p.

Research output: Contribution to journalArticle

161 Citations (Scopus)

Potential of fibroblast cell therapy for recessive dystrophic epidermolysis bullosa

Wong, T., McGrath, J. A., Gammon, L., Leigh, I. M., Navsaria, H., Liu, L., Dopping-Hepenstal, P. J. C., Pacy, J., Mellerio, J. E., Elia, G. & Jeffery, R., 2008, In : Journal of Investigative Dermatology. 128, 9, p. 2179-2189 11 p.

Research output: Contribution to journalArticle

163 Citations (Scopus)