1994 …2022
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Fingerprint Dive into the research topics where Irwin McLean is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 18 Similar Profiles
Atopic Dermatitis Medicine & Life Sciences
Mutation Medicine & Life Sciences
Skin Medicine & Life Sciences
Genes Medicine & Life Sciences
Ichthyosis Vulgaris Medicine & Life Sciences
Pachyonychia Congenita Medicine & Life Sciences
Keratins Medicine & Life Sciences
Psoriasis Medicine & Life Sciences

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Projects 2012 2022

Research Output 1994 2019

50 Downloads (Pure)
Open Access
Lysosphingolipid Receptors
Drug Discovery
Pharmaceutical Preparations

Dog ownership at three months of age is associated with protection against food allergy

EAT Study Team, Marrs, T., Logan, K., Craven, J., Radulovic, S., McLean, W. H. I., Lack, G., Flohr, C. & Perkin, M. R., 8 Jul 2019, In : Allergy. 8 p.

Research output: Contribution to journalArticle

Food Hypersensitivity
Atopic Dermatitis
Environmental Exposure

Filaggrin gene loss-of-function mutations constitute a factor in patients with multiple contact allergies

Elhaji, Y., Sasseville, D., Pratt, M., Asai, Y., Matheson, K., McLean, W. H. I. & Hull, P., Jun 2019, In : Contact Dermatitis. 80, 6, p. 354-358 5 p.

Research output: Contribution to journalArticle

Patch Tests

Male genital lichen sclerosus and filaggrin

Shim, T. N., Brown, S. J., Francis, N. D., Dinneen, M., Hawkins, D., Muneer, A., Minhas, S., McLean, W. H. I. & Bunker, C. B., 17 Jun 2019, In : Clinical and Experimental Dermatology. 2 p.

Research output: Contribution to journalLetter

Lichen Sclerosus et Atrophicus
Skin Diseases
3 Citations (Scopus)
13 Downloads (Pure)

A minimally invasive tool to study immune response and skin barrier in children with atopic dermatitis

Hulshof, L., Hack, D. P., Hasnoe, Q. C. J., Dontje, B., Jakasa, I., Riethmüller, C., McLean, W. H. I., van Aalderen, W. M. C., Van't Land, B., Kezic, S., Sprikkelman, A. B. & Middelkamp-Hup, M. A., 10 Jul 2018, In : British Journal of Dermatology. 10 p.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Chemokine CCL8

Press / Media

Rare skin disease gene discovered

Elizabeth Pohler, Alan Irvine, Toshifumi Nomura, John A. McGrath, W. H. Irwin McLean, Neil Wilson, Frances J. D. Smith, Aileen Sandilands, Christian Cole, Alan Evans, Sara J. Brown & David R. Goudie


1 item of Media coverage

Press/Media: Research

Scientists Discover New Genetic Mutation Linked to Eczema

W. H. Irwin McLean


3 items of Media coverage

Press/Media: Research


Identification and characterization of the gene responsible for the matted mouse phenotype

Author: Goh, C., 2013

Supervisor: Sandilands, A. (Supervisor), McLean, W. (Supervisor) & Crouch, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy


Mouse Models of Inherited Skin Diseases

Author: Fu, D. J., 2014

Supervisor: McLean, W. (Supervisor) & Leslie Pedrioli, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Skin barrier dysfunction in common genetic disorders

Author: Chen, H., 2011

Supervisor: Lane, E. (Supervisor) & McLean, W. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy