Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Projects
- 3 Finished
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Biosensor Analysis of Ligand Interactions with the HERG Ion Channel (Industrial CASE Studentship)
Hopkins, A. (Investigator) & Hopkins Navratilova, I. (Investigator)
30/06/13 → 30/06/17
Project: Research
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European Lead Factory EUC2LID (IMI) (Joint with 29 other Partners)
Alessi, D. (Investigator), Ferguson, M. (Investigator), Hopkins, A. (Investigator), Hopkins Navratilova, I. (Investigator) & Read, K. (Investigator)
Scottish Funding Council, COMMISSION OF THE EUROPEAN COMMUNITIES
1/01/13 → 31/05/18
Project: Research
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K4DD: Kinetics for Drug Discovery (Joint With 19 Other Partners)
Hopkins, A. (Investigator) & Hopkins Navratilova, I. (Investigator)
COMMISSION OF THE EUROPEAN COMMUNITIES
1/11/12 → 31/10/17
Project: Research
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Imidazo[1,2-b]pyridazines as inhibitors of DYRK kinases
Henderson, S. H., Sorrell, F. J., Bennett, J. M., Fedorov, O., Hanley, M. T., Godoi, P. H., Ruela de Sousa, R., Robinson, S., Navratilova, I. H., Elkins, J. M. (Lead / Corresponding author) & Ward, S. E. (Lead / Corresponding author), 5 Apr 2024, In: European Journal of Medicinal Chemistry. 269, 14 p., 116292.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)69 Downloads (Pure) -
Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors
Brem, J. (Lead / Corresponding author), Panduwawala, T., Hansen, J. U., Hewitt, J., Liepins, E., Donets, P., Espina, L., Farley, A. J. M., Shubin, K., Campillos, G. G., Kiuru, P., Shishodia, S., Krahn, D., Leśniak, R. K., Schmidt (Adrian), J., Calvopiña, K., Turrientes, M.-C., Kavanagh, M. E., Lubriks, D. & Hinchliffe, P. & 41 others, , Jan 2022, In: Nature Chemistry. 14, p. 15-24 10 p.Research output: Contribution to journal › Article › peer-review
45 Citations (Scopus) -
Surface Plasmon Resonance Screening to Identify Active and Selective Adenosine Receptor Binding Fragments
Shepherd, C., Robinson, S., Berizzi, A., Thompson, L. E. J., Bird, L., Culurgioni, S., Varzandeh, S., Rawlins, P. B., Olsen, R. H. J. (Lead / Corresponding author) & Hopkins Navratilova, I. (Lead / Corresponding author), 14 Jul 2022, In: ACS Medicinal Chemistry Letters. 13, 7, p. 1172-1181 10 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
Discovery and Characterization of Selective and Ligand-Efficient DYRK Inhibitors
Henderson, S. H. (Lead / Corresponding author), Sorrell, F., Bennett, J., Fedorov, O., Hanley, M. T., Godoi, P. H., Ruela de Sousa, R., Robinson, S., Ashall-Kelly, A., Hopkins Navratilova, I., Walter, D. S., Elkins, J. M. (Lead / Corresponding author) & Ward, S. E. (Lead / Corresponding author), 12 Aug 2021, In: Journal of Medicinal Chemistry. 64, 15, p. 11709-11728 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)131 Downloads (Pure) -
Structure-kinetic relationship reveals the mechanism of selectivity of FAK inhibitors over PYK2
Berger, B. T., Amaral, M., Kokh, D. B., Nunes-Alves, A., Musil, D., Heinrich, T., Schröder, M., Neil, R., Wang, J., Navratilova, I., Bomke, J., Elkins, J. M., Müller, S., Frech, M., Wade, R. C. & Knapp, S. (Lead / Corresponding author), 20 May 2021, In: Cell Chemical Biology. 28, 5, p. 686-698.e7 20 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus)