Munoz, Ivan

Dr

  • United Kingdom

  • 424 Citations
  • 8 h-Index
20072018
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Research Output 2007 2018

  • 424 Citations
  • 8 h-Index
  • 10 Article
  • 1 Review article
2018
5 Citations (Scopus)
106 Downloads (Pure)

Phosphoproteomic screening identifies physiological substrates of the CDKL5 kinase

Munoz, I., Morgan, M., Peltier, J., Weiland, F., Gregorczyk, M., Brown, F. C. M., Macartney, T., Toth, R., Trost, M. & Rouse, J., 14 Dec 2018, In : The EMBO Journal. 37, 24, p. 1-19 19 p., e99559.

Research output: Contribution to journalArticle

Open Access
File
Screening
Phosphotransferases
Serine
Mutation
Substrates
62 Downloads (Pure)

SINHCAF/FAM60A and SIN3A specifically repress HIF 2α expression

Biddlestone, J., Batie, M., Bandarra, D., Munoz, I. & Rocha, S., 29 Jun 2018, In : Biochemical Journal. 475, 12, p. 2073-2090 18 p.

Research output: Contribution to journalArticle

Open Access
File
Co-Repressor Proteins
Transcription Factors
Messenger RNA
Proteins
Hypoxia
2017
83 Downloads (Pure)
Open Access
File
15 Citations (Scopus)
117 Downloads (Pure)

RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health

Feeney, L., Munoz, I. M., Lachaud, C., Toth, R., Appleton, P. L., Schindler, D. & Rouse, J., 1 Jun 2017, In : Molecular Cell. 66, 5, p. 610-621.e4 16 p.

Research output: Contribution to journalArticle

Open Access
File
Replication Protein A
Ubiquitin-Protein Ligases
Health
Fanconi Anemia
Genomic Instability
2015
22 Citations (Scopus)

USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses

Perez-Oliva, A. B., Lachaud, C., Szyniarowski, P., Muñoz, I., Macartney, T., Hickson, I., Rouse, J. & Alessi, D. R., 3 Feb 2015, In : EMBO Journal. 34, 3, p. 326-343 18 p.

Research output: Contribution to journalArticle

Open Access
Endonucleases
DNA Repair
DNA Damage
DNA
Repair
2014
26 Citations (Scopus)
76 Downloads (Pure)

Improved genome editing in human cell lines using the CRISPR method

Munoz, I. M., Szyniarowski, P., Toth, R., Rouse, J. & Lachaud, C., 10 Oct 2014, In : PLoS ONE. 9, 10, 6 p., e109752.

Research output: Contribution to journalArticle

Open Access
File
Clustered Regularly Interspaced Short Palindromic Repeats
human cell lines
gene targeting
Genes
Cells
2012
17 Citations (Scopus)

Family with Sequence Similarity 60A (FAM60A) Protein Is a Cell Cycle-fluctuating Regulator of the SIN3-HDAC1 Histone Deacetylase Complex

Munoz, I. M., Macartney, T., Sanchez-Pulido, L., Ponting, C. P., Rocha, S. & Rouse, J., 21 Sep 2012, In : Journal of Biological Chemistry. 287, 39, p. 32346-53 8 p.

Research output: Contribution to journalArticle

Sin3 Histone Deacetylase and Corepressor Complex
Histone Deacetylase 1
Histone Deacetylases
Cyclin D1
Cell Cycle
2009
25 Citations (Scopus)

Control of histone methylation and genome stability by PTIP

Munoz, I. M. & Rouse, J., Mar 2009, In : EMBO Reports. 10, 3, p. 239-245 7 p.

Research output: Contribution to journalReview article

227 Citations (Scopus)

Coordination of Structure-Specific Nucleases by Human SLX4/BTBD12 Is Required for DNA Repair

Munoz, I. M., Hain, K., Declais, A-C., Gardiner, M., Toh, G. W., Sanchez-Pulido, L., Heuckmann, J. M., Toth, R., Macartney, T., Eppink, B., Kanaar, R., Ponting, C. P., Lilley, D. M. J. & Rouse, J., 10 Jul 2009, In : Molecular Cell. 35, 1, p. 116-127 12 p.

Research output: Contribution to journalArticle

2008
29 Citations (Scopus)

PTIP/Swift is required for efficient PCNA ubiquitination in response to DNA damage

Goehler, T., Munoz, I. M., Rouse, J. & Blow, J. J., 2008, In : DNA Repair. 7, 5, p. 775-787 13 p.

Research output: Contribution to journalArticle

2007
58 Citations (Scopus)
70 Downloads (Pure)

Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage

Munoz, I. M., Jowsey, P. A., Toth, R. & Rouse, J., Aug 2007, In : Nucleic Acids Research. 35, 16, p. 5312-5322 11 p.

Research output: Contribution to journalArticle

Open Access
File
DNA Damage
Epitopes
Proteins
Mutation
Neoplasms