Chalmers, James

Projects

Projects per year 2013 2013 2018 2020 2021 2022 2023 2027

• 4 Not started
• 12 Active
• 31 Finished

Projects per year

Search results

• Active

  Anti-Inflammatory Effects of Dipeptidyl Peptidase-1 Inhibition: A Posthoc Analysis Of The WILLOW Trial

  Chalmers, J. (Investigator)

  1/12/23 → 31/05/26

  Project: Research

• Dipeptidyl Peptidase-1 Reduces Azurocidin-1: Exploring A Novel Anti-Inflammatory Mechanism Of Brensocatib

  Chalmers, J. (Investigator)

  1/12/23 → 31/05/26

  Project: Research

• EMBARC3: Validation Of A Pseudomonas Elastase As A Therapeutic Target

  Chalmers, J. (Investigator)

  LifeArc

  1/08/23 → 30/06/25

  Project: Research

  • Bronchiectasis 100%
  • Microbiome 51%
  • Observational Cohort Study 33%
  • Resistome 33%
  • Clinical Outcomes 33%

• REMAP-CAP Influenza (joint with Imperial College London)

  Chalmers, J. (Investigator)

  1/12/22 → 30/11/25

  Project: Research

• GREAT-2: A phase 2 trial of Gremubamab compared to placebo in participants with bronchiectasis and chronic Pseudomonas aeruginosa infection

  Chalmers, J. (Investigator)

  European Respiratory Society

  1/11/22 → 31/10/25

  Project: Research

  • Bronchiectasis 100%
  • PcrV 50%
  • Prescribing Preference 50%
  • Inhaled Medications 50%
  • Antibody Targeting 50%

• The European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC 3)

  Chalmers, J. (Investigator)

  1/07/22 → 31/12/25

  Project: Research

  • Bronchiectasis 100%
  • Asthma 50%
  • Molecular Endotype 50%
  • Multicenter Cohort Study 50%
  • EMBARC 50%

• A Randomised Controlled Trial Of A Facilitated Home-Based Rehabilitation Intervention In Patients With Heart Failure With Preserved Ejection Fraction And Their Caregivers: The REACH-HFpEF Study (Joint with NHST)

  Chalmers, J. (Investigator) & Mordi, I. (Investigator)

  1/03/22 → 31/12/25

  Project: Research

• PHOS-COVID (Joint with University of Leicester)

  Chalmers, J. (Investigator) & Dicker, A. (Investigator)

  Medical Research Council

  1/04/21 → 31/03/26

  Project: Research

  • COVID-19 100%
  • Hospitalization 48%
  • Rehospitalization 30%
  • Cohort Analysis 30%
  • Hospital Admission 24%

• Understanding and Predicting the Evolution of Antibiotic Resistance in Human Infection (other institutions, joint lead Dundee/Sheffield Uni, Liverpool Uni))

  Chalmers, J. (Investigator)

  1/02/21 → 31/01/27

  Project: Research

  • Antimicrobial Resistance 100%
  • Resistance Emergence 66%
  • Evolution Mechanism 66%
  • Ecological Mechanism 66%
  • Pseudomonas Aeruginosa (P. aeruginosa) 66%

• Pollution and Air Quality Management Area (AQMA)

  Belch, J. (Investigator), Chalmers, J. (Investigator) & Geddes, A. (Investigator)

  The Institute of Cardiovascular Research

  1/02/19 → 31/12/25

  Project: Research

• EMBARC2 - European Bronchiectasis Registry and Biobank

  Chalmers, J. (Investigator)

  European Respiratory Society

  1/12/18 → 1/10/26

  Project: Research

  • Bronchiectasis 100%
  • Chronic Obstructive Pulmonary Disease 28%
  • Hazard Ratio 24%
  • Pseudomonas aeruginosa 23%
  • Confidence Interval 23%

• The British Lung Foundation/GSK Centre for Bronchiectasis Research

  Chalmers, J. (Investigator)

  British Lung Foundation

  1/11/17 → 31/10/27

  Project: Research

  • Bronchiectasis 100%
  • Sputum 42%
  • Interim Analysis 35%
  • Neisseria Species 35%
  • Nontuberculous Mycobacterial Lung Disease 35%
• Not started

  Molecular Diagnosis of Bacterial Infection in the Lung

  Chalmers, J. (Investigator)

  Project: Research

• END Covid, ERS - Data Sharing Collaboration led by Madrid and Milan -

  Chalmers, J. (Investigator)

  Project: Research

• Antibiotic Exposure And Loss Of Lung Microbiome Diversity In COPD: Linkage Of Routine Health Records And Airway Sequencing Data

  Chalmers, J. (Investigator) & Dicker, A. (Investigator)

  Project: Research

• Validating New Methods for Identifying Neutrophil Extracellular Traps In-Vivo

  Chalmers, J. (Investigator)

  Project: Research

• Finished

  Transcriptomic Signatures Of Airway Microbial Dysbiosis In COPD

  Chalmers, J. (Investigator)

  1/11/23 → 31/10/24

  Project: Research

• Understanding Infection, Viral Exacerbation And Respiratory Symptoms At Admission - Longitudinal (UNIVERSAL) Study (NRS22/320087) - Joint with University Hospital Southampton NHS Foundation Trust

  Chalmers, J. (Investigator)

  1/09/23 → 31/01/24

  Project: Research

• Is Neutrophil Inflammatory Phenotype Regulated By Olfactomedin-4 In Bronchiectasis (Clinical Academic Fellowship)

  Chalmers, J. (Investigator) & Shoemark, A. (Investigator)

  1/04/22 → 31/03/25

  Project: Research

  • Bronchiectasis 100%
  • Biological Marker 100%
  • Diseases 83%
  • Disease Pattern 33%
  • Clinical Practice 16%

• Validation Of A Biomarker For COVID19 Infection

  Chalmers, J. (Investigator)

  1/10/21 → 30/09/22

  Project: Research

• Inflammatory Drivers Of endothelial Dysfunction In COVID-19

  Chalmers, J. (Investigator) & Khan, F. (Investigator)

  1/07/21 → 30/06/24

  Project: Research

• Evaluating Emerging Models Of Community Rehabilitation For People Experiencing The Effects Of Long-COVID To Inform Responsive Service Delivery Across Scotland (Joint with Robert Gordon University and Stirling University)

  Chalmers, J. (Investigator) & Morris, J. (Investigator)

  1/05/21 → 30/04/23

  Project: Research

  • Community-based Rehabilitation 100%
  • Long COVID 100%
  • Living with 100%
  • Postcovid Syndrome 100%
  • Scottish 75%

• European Respiratory Society Short Guidelines On The Management Of COVID19

  Chalmers, J. (Investigator)

  European Respiratory Society

  1/04/21 → 31/03/22

  Project: Research

  • Living Guidelines 100%
  • COVID-19 100%
  • European Respiratory Society 100%
  • Hospitalized Adults 100%
  • Coronavirinae 100%

• Bronchodilators in Bronchiectasis Study (BIBS Study)

  Chalmers, J. (Investigator)

  1/02/21 → 31/01/25

  Project: Research

• CO-CONNECT: COVID - Curated and Open Analysis and Research Platform (UKRI Open Call - UKRI Ideas to Address COVID-19) (Joint with University of Nottingham and 17 others)

  Chalmers, J. (Investigator), Jefferson, E. (Investigator) & Morales, D. (Investigator)

  Medical Research Council

  29/10/20 → 27/10/22

  Project: Research

  • Data Model 100%
  • Observational Medical Outcomes Partnership 56%
  • Coronavirus Disease (COVID) 52%
  • Lessons Learned 50%
  • Data Controller 50%

• A randomized controlled trial of SFX-01 to improve clinical outcomes in COVID-19 patients (STAR-COVID)

  Chalmers, J. (Investigator) & Dinkova-Kostova, A. (Investigator)

  LifeArc

  1/08/20 → 30/09/22

  Project: Research

• Rapid Research in Covid -19 Programme

  Barrable, A. (Investigator), Belch, J. (Investigator), Boehnke, J. (Investigator), Booth, D. (Investigator), Brown, A. (Investigator), Cantrell, D. (Investigator), Chalmers, J. (Investigator), Coleman, S. (Investigator), Connell, D. (Investigator), Cuschieri, A. (Investigator), Dicker, A. (Investigator), Doney, A. (Investigator), Eftimie, R. (Investigator), Fang, M. (Investigator), Farre, A. (Investigator), Gamble, C. (Investigator), Howden, A. (Investigator), Krstajic, N. (Investigator), Lamond, A. (Investigator), Moraga Gonzalez, I. (Investigator), Palmer, C. (Investigator), Parcell, B. (Investigator), Pearson, E. (Investigator), Shoemark, A. (Investigator) & Sixsmith, J. (Investigator)

  1/06/20 → 30/09/21

  Project: Research

  • COVID-19 100%
  • Neutrophils 66%
  • Hyperinflammation 33%
  • Resilience 33%
  • T Cell Activation 33%

• MATCH Antibody Study

  Chalmers, J. (Investigator)

  1/06/20 → 31/08/20

  Project: Research

• Rapid Diagnosis of Bacterial Co-Infection and Antimicrobial Resistance in Patients with Severe Acute Respiratory Syndrome Coronavirus 2 Infection (SARS-CoV-2)

  Chalmers, J. (Investigator), Connell, D. (Investigator) & Parcell, B. (Investigator)

  1/05/20 → 31/10/21

  Project: Research

• Dundee Centre for Antimicrobial Resistance

  Chalmers, J. (Investigator), Coulthurst, S. (Investigator), Jefferson, E. (Investigator), Marwick, C. (Investigator), Nathwani, D. (Investigator) & Palmer, C. (Investigator)

  1/09/19 → 31/03/22

  Project: Research

• Development of Biomarkers to Identify Inhaled Antibiotic Response in Bronchiectasis (Full App)

  Chalmers, J. (Investigator)

  1/06/19 → 31/05/22

  Project: Research

• RD REGISTRY DATA WAREHOUSE

  Chalmers, J. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/04/18 → 30/11/21

  Project: Research

• An In-Vitro Airway Model of Bronchiectasis

  Chalmers, J. (Investigator) & Shoemark, A. (Investigator)

  13/03/18 → 12/03/19

  Project: Research

• Demusine as a Profounding Biomarker for Abdominal Aortic Aneurysm - DESUMA AAA Study

  Chalmers, J. (Investigator), Choy, A.-M. (Investigator), Lang, C. (Investigator) & Mordi, I. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/03/18 → 30/11/21

  Project: Research

  • Type 2 Diabetic Patients 100%
  • Microvascular Disease 100%
  • Marfan Syndrome 100%
  • Aortopathy 100%
  • Heart Failure with Preserved Ejection Fraction (HFpEF) 100%

• A Randomized Controlled Trial of Nebulised Hypertonic Saline in Bronchiectasis (joint with QUB, Newcastle & Southampton) (NIHR HTA)

  Chalmers, J. (Investigator)

  1/03/18 → 28/02/22

  Project: Research

• Scottish Senior Clinical Fellowship

  Chalmers, J. (Investigator)

  Chief Scientist Office

  1/01/18 → 1/07/23

  Project: Research

  • Bronchiectasis 100%
  • Sputum 20%
  • Bronchiectasis Exacerbation 19%
  • Microbiomics 17%
  • Pathobiont 17%

• Romain Pauwels Research Award

  Chalmers, J. (Investigator)

  European Respiratory Society

  1/11/17 → 31/10/19

  Project: Research

• Pregnancy Zone Protein in the Lung - Investigating Gender Differences in Development and Prognosis of Bronchiectasis (Clinical Academic Fellowship)

  Chalmers, J. (Investigator) & Finch, S. (Investigator)

  1/02/17 → 31/01/20

  Project: Research

  • Bronchiectasis 100%
  • Respiratory Tract Infection 47%
  • Lung Function Decline 29%
  • Disease Severity 29%
  • Cystic Fibrosis 28%

• Development of Risk Prediction Score for Cardiac Death in Patients Prescribed with Macrolide Antibiotics for Acute Respiratory Infections

  Chalmers, J. (Investigator), Lang, C. (Investigator) & Mordi, I. (Investigator)

  1/08/16 → 31/07/18

  Project: Research

• Determining the Efficacy of Plasmapheresis as a Treatment for Patients with Chronic Pseudomonas Infections and Inhibitory Antibodies (joint with Universities of Birmingham and Newcastle upon Tyne)

  Chalmers, J. (Investigator)

  Medical Research Council

  1/06/16 → 31/05/19

  Project: Research

• The Impact of Antimicrobial Exposure on Subsequent Antimicrobial Resistance in Patients with COPD and Bronchiectasis

  Chalmers, J. (Investigator), Donnan, P. (Investigator), Marwick, C. (Investigator) & Nathwani, D. (Investigator)

  1/02/16 → 31/01/18

  Project: Research

• Inhaled Antibiotics in Bronchiectasis and Cystic Fibrosis (iABC) (Joint with 19 Partners)

  Chalmers, J. (Investigator) & Shoemark, A. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/09/15 → 30/06/23

  Project: Research

  • Bronchiectasis 100%
  • EMBARC 23%
  • Clinical Outcomes 17%
  • Quality of Life 14%
  • Sputum 14%

• Characterisation of a Novel Staphylococcus Aureus Virulence System Critical to Lung Colonisation in Cystic Fibrosis

  Chalmers, J. (Investigator) & Palmer, T. (Investigator)

  1/06/14 → 31/05/16

  Project: Research

• Mannose Binding Lectin Deficiency, Bacterial Infection and Disease Severity in Chronic Obstructive Pulmonary Disease: Towards Personalised Medicine for COPD

  Chalmers, J. (Investigator), Marshall, S. (Investigator), Palmer, C. (Investigator) & Schembri, S. (Investigator)

  1/07/13 → 30/06/15

  Project: Research

  • Mannose-binding Lectin Deficiency 100%
  • Microbial Diversity 100%
  • Disease Severity 100%
  • Lectin Binding 100%
  • Microflora 100%

• A Pilot Study of Pulmonary Rehabilitation After Exacerbations of Bronchiectasis

  Chalmers, J. (Investigator), Fardon, T. (Investigator) & Stretton, R. (Investigator)

  1/05/13 → 31/10/16

  Project: Research

• Investigating the Association Between Inhaled Corticosteroids and Pneumonia in Chronic Obstructive Pulmonary Disease: The Effect of Inhaled Steroids on Microbial Community Composition

  Chalmers, J. (Investigator), Lipworth, B. (Investigator), Palmer, C. (Investigator) & Schembri, S. (Investigator)

  1/01/13 → 30/09/14

  Project: Research

• The Role in ESX-1, a Novel Protein Secretion System, in Staphylococcus Aureus Virulence (Clinical Fellowship - James Chalmers)

  Chalmers, J. (Investigator) & Palmer, T. (Investigator)

  1/01/13 → 31/12/15

  Project: Research

  • Staphylococcus Aureus 100%
  • Mortality Risk 100%
  • Exacerbation Rate 100%
  • Microbial Diversity 100%
  • Type VII Secretion System 100%