Hastie, James


  • Deputy Manager - Signal Transduction Therapy, MRC PPU
  • United Kingdom

  • 2725 Citations
  • 16 h-Index
If you made any changes in Pure these will be visible here soon.

Fingerprint Dive into the research topics where James Hastie is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 7 Similar Profiles
Phosphorylation Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Assays Chemical Compounds
Glycogen Synthase Kinase 3 Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
SMN Complex Proteins Medicine & Life Sciences
Microtubules Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2003 2018

  • 2725 Citations
  • 16 h-Index
  • 25 Article

Corrigendum to "Characterisation of the sites of DNA damage-induced 53BP1 phosphorylation catalysed by ATM and ATR" [DNA Repair 6 (2007) 1536-1544]

Jowsey, P., Morrice, N. A., Hastie, C. J., MacLauchlan, H., Toth, R. & Rouse, J., May 2018, In : DNA Repair. 65, p. 80 1 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
56 Downloads (Pure)

The MALDI TOF E2/E3 ligase assay as universal tool for drug discovery in the ubiquitin pathway

De Cesare, V., Johnson, C., Barlow, V., Hastie, C., Knebel, A. & Trost, M., 20 Sep 2018, In : Cell Chemical Biology. 25, 9, p. 1117-1127.4 11 p.

Research output: Contribution to journalArticle

Open Access
Ubiquitin-Protein Ligases
Drug Discovery
17 Citations (Scopus)
67 Downloads (Pure)

CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis

Sonneville, R., Priego Moreno, S., Knebel, A., Johnson, C., Hastie, C. J., Gartner, A., Gambus, A. & Labib, K., 3 Apr 2017, In : Nature Cell Biology. 19, p. 468-479 11 p.

Research output: Contribution to journalArticle

Open Access
DNA Replication
Centers for Disease Control and Prevention (U.S.)
15 Citations (Scopus)
164 Downloads (Pure)

Identifying Inhibitors of Inflammation: A Novel High-Throughput MALDI-TOF Screening Assay for Salt-Inducible Kinases (SIKs)

Heap, R. E., Hope, A. G., Pearson, L-A., Reyskens, K. M. S. E., McElroy, S. P., Hastie, C. J., Porter, D. W., Arthur, J. S. C., Gray, D. W. & Trost, M., 1 Dec 2017, In : SLAS Discovery. 22, 10, p. 1193-1202 10 p.

Research output: Contribution to journalArticle

Open Access
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
1 Citation (Scopus)
87 Downloads (Pure)

Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3)

Logie, L., Van Aalten, L., Knebel, A., Force, T., Hastie, C. J., MacLauchlan, H., Campbell, D. G., Gourlay, R., Prescott, A., Davidson, J., Fuller, W. & Sutherland, C., 15 Dec 2017, In : Scientific Reports. 7, p. 1-14 14 p., 17682.

Research output: Contribution to journalArticle

Open Access
rab GTP-Binding Proteins
Glycogen Synthase Kinase 3
Carrier Proteins
rab5 GTP-Binding Proteins