Hastie, James

Dr

  • Deputy Manager - Signal Transduction Therapy, MRC PPU
  • United Kingdom

  • 2791 Citations
  • 18 h-Index
20032018
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Fingerprint Dive into the research topics where James Hastie is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Phosphorylation Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Assays Chemical Compounds
Glycogen Synthase Kinase 3 Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
SMN Complex Proteins Medicine & Life Sciences
Microtubules Medicine & Life Sciences

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Research Output 2003 2018

  • 2791 Citations
  • 18 h-Index
  • 25 Article

Corrigendum to "Characterisation of the sites of DNA damage-induced 53BP1 phosphorylation catalysed by ATM and ATR" [DNA Repair 6 (2007) 1536-1544]

Jowsey, P., Morrice, N. A., Hastie, C. J., MacLauchlan, H., Toth, R. & Rouse, J., May 2018, In : DNA Repair. 65, p. 80 1 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
64 Downloads (Pure)

The MALDI TOF E2/E3 ligase assay as universal tool for drug discovery in the ubiquitin pathway

De Cesare, V., Johnson, C., Barlow, V., Hastie, C., Knebel, A. & Trost, M., 20 Sep 2018, In : Cell Chemical Biology. 25, 9, p. 1117-1127.4 11 p.

Research output: Contribution to journalArticle

Open Access
File
Ubiquitin-Protein Ligases
Drug Discovery
Ubiquitin
Ionization
Assays
21 Citations (Scopus)
82 Downloads (Pure)

CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis

Sonneville, R., Priego Moreno, S., Knebel, A., Johnson, C., Hastie, C. J., Gartner, A., Gambus, A. & Labib, K., 3 Apr 2017, In : Nature Cell Biology. 19, p. 468-479 11 p.

Research output: Contribution to journalArticle

Open Access
File
DNA Replication
Mitosis
Chromatin
Ubiquitination
Centers for Disease Control and Prevention (U.S.)
18 Citations (Scopus)
183 Downloads (Pure)

Identifying Inhibitors of Inflammation: A Novel High-Throughput MALDI-TOF Screening Assay for Salt-Inducible Kinases (SIKs)

Heap, R. E., Hope, A. G., Pearson, L-A., Reyskens, K. M. S. E., McElroy, S. P., Hastie, C. J., Porter, D. W., Arthur, J. S. C., Gray, D. W. & Trost, M., 1 Dec 2017, In : SLAS Discovery. 22, 10, p. 1193-1202 10 p.

Research output: Contribution to journalArticle

Open Access
File
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Assays
Screening
Phosphotransferases
Salts
2 Citations (Scopus)
102 Downloads (Pure)

Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3)

Logie, L., Van Aalten, L., Knebel, A., Force, T., Hastie, C. J., MacLauchlan, H., Campbell, D. G., Gourlay, R., Prescott, A., Davidson, J., Fuller, W. & Sutherland, C., 15 Dec 2017, In : Scientific Reports. 7, p. 1-14 14 p., 17682.

Research output: Contribution to journalArticle

Open Access
File
rab GTP-Binding Proteins
Glycogen Synthase Kinase 3
Carrier Proteins
Phosphorylation
rab5 GTP-Binding Proteins