Projects per year
Personal profile
Biography
Jenni Harvey obtained a BSc honours degree in Pharmacology at the University of Edinburgh (1990) before receiving a Ph.D. in 1993 for work on metabotropic glutamate receptors and synaptic transmission under the supervision of Prof Graham Collingridge (University of Birmingham). She then undertook postdoctoral research positions with Dr Mike Lacey (University of Birmingham) and Prof Mike AShford (University of Aberdeen), before moving to Dundee to set up her own laboratory after being awarded a Wellcome Research Career Development Fellowship (2001). In 2005, she was awarded a Wellcome University Award to continue her studies into the role of leptin in hippocampal synaptic function.
Teaching
Undergraduate Science Teaching
5th Year MSCi in Pharmacology/Neuroscience
4th year BSc & BMSc Honours in Pharmacology
4th year BSc & BMSc Honours in Neuroscience
Module Course - Synaptic plasticity and cognition
Module Course Leader - Neurodegenerative Disorders
Supervision of 4th year BSc and BMSc Honours Student Projects
3rd year BSc
Quantitative Pharmacology module
Molecular Pharmacology module
Regulatory Physiology and Pharmacology module
Biomembranes module
Undergraduate Medical Student Teaching
1st year Medical Special Study Component (SSC)
1st year tutorials
Supervision of Medical Students in their 4th year laboratory-based assignment
Postgraduate Teaching
I have extensive experience of supervising both MSc and PhD students.
Research
Jenni Harvey’s research group has a long standing interest in neuronal synaptic mechanisms and in particular the cellular basis for activity-dependent synaptic plasticity in the CNS. Her research is focused on understanding how the molecular processes of synaptic plasticity are influenced by hormonal systems in health and disease. Recent studies by the group have highlighted a potential cognitive enhancing role for leptin as it regulates diverse aspects of synaptic function including glutamate receptor trafficking, neuronal morphology and activity dependent synaptic plasticity. A major focus of her current research is in determining the cellular and molecular processes underlying leptin’s effects in the brain and also how dysfunctions in the leptin system impact on brain function. Her group are utilizing a range of techniques including electrophysiology, digital epifluorescence imaging, transgenic mouse technologies, molecular biology and confocal microscopy to determine the neuronal function of the hormone leptin.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Network
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Evaluation of the Potential use of Leptin Mimetics in the Treatment of Neurodegenerative Disorders
Harvey, J. & Irving, A.
Project: Research
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Does Leptin Have Pathway-Specific Effects on the Regulation of Hippocampal Excitatory Synaptic Transmission
Harvey, J., Irving, A. & Luo, X.
Project: Research
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Leptin regulation of synaptic function at hippocampal TA-CA1 and SC-CA1 synapses
Harvey, J., 16 Feb 2022, Hormones, Regulators and Hippocampus. Litwack, G. (ed.). Academic Press Inc., Vol. 118. p. 315-336 22 p. (Vitamins and Hormones; vol. 118).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Leptin regulation of hippocampal synaptic function in health and disease
Hamilton, K. & Harvey, J., 2021, Hormones and Aging. Litwack, G. (ed.). Academic Press Inc., Vol. 115. p. 105-127 23 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Citation (Scopus) -
Regulation of hippocampal synaptic function by the metabolic hormone leptin: implications for health and disease
Irving, A. & Harvey, J., Apr 2021, In: Progress in Lipid Research. 82, 7 p., 101098.Research output: Contribution to journal › Review article › peer-review
Open AccessFile2 Citations (Scopus)1 Downloads (Pure) -
The Neuronal Actions of Leptin and the Implications for Treating Alzheimer's Disease
Hamilton, K. & Harvey, J., 11 Jan 2021, In: Pharmaceuticals . 14, 1, p. 1-14 14 p., 52.Research output: Contribution to journal › Review article › peer-review
Open AccessFile3 Citations (Scopus)203 Downloads (Pure) -
Activation of oestrogen receptor α induces a novel form of LTP at hippocampal temporoammonic-CA1 synapses
Clements, L. & Harvey, J., 11 Feb 2020, In: British Journal of Pharmacology. 177, 3, p. 642-655 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)101 Downloads (Pure)
Prizes
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Wellcome Trust Research Career Development Fellowship
Harvey, Jenni (Recipient), 1999
Prize: Fellowship awarded competitively
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Wellcome Trust University Award
Harvey, Jenni (Recipient), 2005
Prize: Fellowship awarded competitively
Activities
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School of Medicine: Women in Science Day
Jenni Harvey (Organiser)
11 Feb 2021Activity: Participating in or organising an event types › Other event
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Alzheimer's Society Volunteer Network
Jenni Harvey (Member)
Sep 2020Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Alzheimer's Research UK (External organisation)
Jenni Harvey (Member)
2020 → …Activity: Membership types › Membership of board
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Black History Month: BMA Race Charter
Jenni Harvey (Presenter)
Oct 2020Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Alzheimer's Society Volunteer Network: Research showcase day
Jenni Harvey (Member)
Feb 2020Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar