Harvey, Jenni

Dr

  • 1985 Citations
  • 23 h-Index
19982019
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Research Output 1998 2019

2019
6 Citations (Scopus)
92 Downloads (Pure)

Leptin Regulation of Synaptic Function at Hippocampal TA-CA1 and SC-CA1 Synapses: Implications for Health and Disease

Mcgregor, G. & Harvey, J., Mar 2019, In : Neurochemical Research. 44, 3, p. 650-660 11 p.

Research output: Contribution to journalArticle

Open Access
File
Leptin
Synapses
Hippocampus
Health
Alzheimer Disease
2018
3 Citations (Scopus)
96 Downloads (Pure)

Age-dependent regulation of excitatory synaptic transmission at hippocampal temporoammonic-CA1 synapses by leptin

McGregor, G., Clements, L., Farah, A., Irving, A. & Harvey, J., Sep 2018, In : Neurobiology of Aging. 69, p. 76-93 18 p.

Research output: Contribution to journalArticle

Open Access
File
Leptin
Synaptic Transmission
Synapses
Depression
Hippocampus
4 Citations (Scopus)
110 Downloads (Pure)

Food for thought: Leptin regulation of hippocampal function and its role in Alzheimer's disease

McGregor, G. & Harvey, J., Jul 2018, In : Neuropharmacology. 136, p. 298-306 9 p.

Research output: Contribution to journalReview article

Open Access
File
Leptin
Alzheimer Disease
Body Weight
Neurobiology
Neurodegenerative Diseases
3 Citations (Scopus)
65 Downloads (Pure)
Open Access
File
Leptin
Neurodegenerative Diseases
Hormones
Health
Alzheimer Disease
2017
10 Citations (Scopus)

Cannabinoid Receptor-Related Orphan G Protein-Coupled Receptors

Irving, A., Abdulrazzaq, G., Chan, S. L. F., Penman, J., Harvey, J. & Alexander, S. P. H., Jun 2017, Cannabinoid Pharmacology. Kendall, D. & Alexander, S. P. H. (eds.). Cambridge, MA: Academic Press, Vol. 80. p. 223-247 25 p. (Advances in Pharmacology; vol. 80).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Cannabinoid Receptor CB2
Cannabinoid Receptor CB1
Cannabinoid Receptors
G-Protein-Coupled Receptors
Ligands
5 Citations (Scopus)

Canonical JAK-STAT signaling is pivotal for long-term depression at adult hippocampal temporoammonic-CA1 synapses

McGregor, G., Irving, A. J. & Harvey, J., Aug 2017, In : FASEB Journal. 31, 8, p. 3449-3466 19 p.

Research output: Contribution to journalArticle

Janus Kinases
Transcription
Transducers
Synapses
Depression
19 Citations (Scopus)
104 Downloads (Pure)

Emerging roles for the novel estrogen-sensing receptor GPER1 in the CNS

Alexander, A., Irving, A. J. & Harvey, J., Feb 2017, In : Neuropharmacology. 113, Part B, p. 652-660 9 p.

Research output: Contribution to journalArticle

Open Access
File
Estrogen Receptors
Estrogens
Steroid Receptors
Cytoplasmic and Nuclear Receptors
G-Protein-Coupled Receptors
2016
11 Citations (Scopus)
62 Downloads (Pure)

A Leptin Fragment Mirrors the Cognitive Enhancing and Neuroprotective Actions of Leptin

Malekizadeh, Y., Holiday, A., Redfearn, D., Ainge, J. A., Doherty, G. & Harvey, J., 6 Sep 2016, In : Cerebral Cortex. 27, 10, p. 4769-4782 14 p.

Research output: Contribution to journalArticle

Open Access
File
Leptin
leptin (116-130)
Alzheimer Disease
Amyloid
Neuronal Plasticity
2015
17 Citations (Scopus)
71 Downloads (Pure)

Leptin induces a novel form of NMDA receptor-dependent LTP at hippocampal termporoammonic-CA1 synapses

Luo, X., McGregor, G., Irving, A. J. & Harvey, J., 26 May 2015, In : eNeuro. 2, 3, 17 p.

Research output: Contribution to journalArticle

Open Access
File
Leptin
N-Methyl-D-Aspartate Receptors
Synapses
Synaptic Transmission
Hippocampus
17 Citations (Scopus)

Minireview: food for thought: regulation of synaptic function by metabolic hormones

McGregor, G., Malekizadeh, Y. & Harvey, J., Jan 2015, In : Molecular Endocrinology. 29, 1, p. 3-13 11 p.

Research output: Contribution to journalArticle

Leptin
Hormones
Insulin
Central Nervous System Diseases
Hippocampus
2014
4 Citations (Scopus)

Honeybee Kenyon cells are regulated by a tonic GABA receptor conductance

Palmer, M. J. & Harvey, J., 15 Oct 2014, In : Journal of Neurophysiology. 112, 8, p. 2026-2035 10 p.

Research output: Contribution to journalArticle

GABA Receptors
Mushroom Bodies
gamma-Aminobutyric Acid
Insects
Picrotoxin
53 Citations (Scopus)

Leptin regulation of hippocampal synaptic function in health and disease

Irving, A. J. & Harvey, J., Jan 2014, In : Philosophical Transactions of the Royal Society B - Biological Sciences. 369, 1633, 20130155.

Research output: Contribution to journalArticle

Leptin
leptin
Health
Alzheimer disease
Alzheimer Disease
2013
107 Citations (Scopus)

Cholinergic pesticides cause mushroom body neuronal inactivation in honeybees

Palmer, M. J., Moffat, C., Saranzewa, N., Harvey, J., Wright, G. A. & Connolly, C. N., 27 Mar 2013, In : Nature Communications. 4, 1634.

Research output: Contribution to journalArticle

Open Access
cholinergics
Mushroom Bodies
pesticides
Pesticides
deactivation
70 Citations (Scopus)

Leptin prevents hippocampal synaptic disruption and neuronal cell death induced by amyloid β.

Doherty, G. H., Beccano-Kelly, D., Yan, S-D., Gunn-Moore, F. & Harvey, J., Jan 2013, In : Neurobiology of Aging. 34, 1, p. 226-37

Research output: Contribution to journalArticle

Leptin
Amyloid
Cell Death
Alzheimer Disease
Nootropic Agents
2012
6 Citations (Scopus)

PTEN: a new player controlling structural and functional synaptic plasticity

Blair, P. J. & Harvey, J., Feb 2012, In : Journal of Physiology. 590, 5, p. 1017-1017 1 p.

Research output: Contribution to journalArticle

2011
35 Citations (Scopus)

NMDA receptor subunit composition determines the polarity of leptin-induced synaptic plasticity

Moult, P. R. & Harvey, J., 2011, In : Neuropharmacology. 61, 5-6, p. 924-936 13 p.

Research output: Contribution to journalArticle

2010
20 Citations (Scopus)

Leptin: The Missing Link in Alzheimer Disease?

Harvey, J., May 2010, In : Clinical Chemistry. 56, 5, p. 696-697 2 p.

Research output: Contribution to journalEditorial

69 Citations (Scopus)

Leptin Regulates AMPA Receptor Trafficking via PTEN Inhibition

Moult, P. R., Cross, A., Santos, S. D., Carvalho, A-L., Lindsay, Y., Connolly, C. N., Irving, A. J., Leslie, N. R. & Harvey, J., 17 Mar 2010, In : Journal of Neuroscience. 30, 11, p. 4088-4101 14 p.

Research output: Contribution to journalArticle

2009
18 Citations (Scopus)

Bi-directional modulation of fast inhibitory synaptic transmission by leptin

Solovyova, N., Moult, P. R., Milojkovic, B., Lambert, J. J. & Harvey, J., Jan 2009, In : Journal of Neurochemistry. 108, 1, p. 190-201 12 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Leptin reverses long-term potentiation at hippocampal CA1 synapses

Moult, P. R., Milojkovic, B. & Harvey, J., Feb 2009, In : Journal of Neurochemistry. 108, 3, p. 685-696 12 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Regulation of glutamate receptor trafficking by leptin

Moult, P. R. & Harvey, J., Dec 2009, In : Biochemical Society Transactions. 37, p. 1364-1368 5 p.

Research output: Contribution to journalArticle

2008
42 Citations (Scopus)

Hormonal regulation of hippocampal dendritic morphology and synaptic plasticity

Moult, P. R. & Harvey, J., 1 Oct 2008, In : Cell Adhesion and Migration. 2, 4, p. 269-275 7 p.

Research output: Contribution to journalArticle

Neuronal Plasticity
Hormones
Epilepsy
Hippocampus
Learning

Neurobiology of obesity

Harvey, J. (ed.) & Withers, D. J. (ed.), 2008, Cambridge: Cambridge University Press. 324 p.

Research output: Book/ReportBook

Neurobiology
Obesity
Appetite Depressants
Adiposity
Health
38 Citations (Scopus)

Neuroprotective actions of leptin on central and peripheral neurons in vitro

Doherty, G. H., Oldreive, C. & Harvey, J., 17 Jul 2008, In : Neuroscience. 154, 4, p. 1297-1307 11 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Neurotrophic effects of leptin on cerebellar Purkinje but not granule neurons in vitro

Oldreive, C. E., Harvey, J. & Doherty, G. H., 2008, In : Neuroscience Letters. 438, 1, p. 17-21 5 p.

Research output: Contribution to journalArticle

2007
100 Citations (Scopus)

Leptin: a diverse regulator of neuronal function

Harvey, J., Jan 2007, In : Journal of Neurochemistry. 100, 2, p. 307-313 7 p.

Research output: Contribution to journalArticle

Leptin
Hormones
Large-Conductance Calcium-Activated Potassium Channels
Leptin Receptors
Synaptic Transmission
119 Citations (Scopus)

Leptin promotes rapid dynamic changes in hippocampal dendritic morphology

O'Malley, D., MacDonald, N., Mizielinska, S., Connolly, C. N., Irving, A. J. & Harvey, J., Aug 2007, In : Molecular and Cellular Neuroscience. 35, 4, p. 559-572 14 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)

Leptin regulation of neuronal excitability and cognitive function

Harvey, J., Dec 2007, In : Current Opinion in Pharmacology. 7, 6, p. 643-647 5 p.

Research output: Contribution to journalReview article

29 Citations (Scopus)

MAPK-dependent actin cytoskeletal reorganization underlies BK channel activation by insulin

O'Malley, D. & Harvey, J., 2007, In : European Journal of Neuroscience. 25, 3, p. 673-682 10 p.

Research output: Contribution to journalArticle

Large-Conductance Calcium-Activated Potassium Channels
Mitogen-Activated Protein Kinases
Actins
Insulin
Actin Cytoskeleton
72 Citations (Scopus)

Mitochondrial dysfunction and dendritic beading during neuronal toxicity

Greenwood, S. M., Mizielinska, S. M., Frenguelli, B. G., Harvey, J. & Connolly, C. N., 7 Sep 2007, In : Journal of Biological Chemistry. 282, 36, p. 26235-26244 10 p.

Research output: Contribution to journalArticle

2005
53 Citations (Scopus)

Leptin-induced dynamic alterations in the actin cytoskeleton mediate the activation and synaptic clustering of BK channels

O'Malley, D., Irving, A. J. & Harvey, J., Nov 2005, In : FASEB Journal. 19, 11, p. 1917-1919 3 p.

Research output: Contribution to journalArticle

Large-Conductance Calcium-Activated Potassium Channels
Leptin
Actin Cytoskeleton
Cluster Analysis
Actins
2004
3 Citations (Scopus)

The aminoguanidine carboxylate BVT.12777 activates ATP-sensitive K+ channels in the rat insulinoma cell line, CRI-G1

Kinsella, J. M., Laidlaw, H. A., Tang, T., Harvey, J., Sutherland, C. & Ashford, M. L. J., 2004, In : BMC Clinical Pharmacology. 4, 17, 13 p.

Research output: Contribution to journalArticle

Obese Mice
KATP Channels
Insulinoma
Leptin
Adenosine Triphosphate
2003
103 Citations (Scopus)

Leptin in the CNS: much more than a satiety signal

Harvey, J. & Ashford, M. L. J., Jun 2003, In : Neuropharmacology. 44, 7, p. 845-54 10 p.

Research output: Contribution to journalArticle

Leptin
Nutritional Status
Osteogenesis
Hormones
2002
140 Citations (Scopus)

Leptin inhibits epileptiform-like activity in rat hippocampal neurones via PI 3-kinase-driven activation of BK channels

Shanley, L. J., O'Malley, D., Irving, A. J., Ashford, M. L. & Harvey, J., Dec 2002, In : Journal of Physiology. 545, 3, p. 933-944 12 p.

Research output: Contribution to journalArticle

Large-Conductance Calcium-Activated Potassium Channels
1-Phosphatidylinositol 4-Kinase
Leptin
Neurons
Leptin Receptors
70 Citations (Scopus)

Leptin inhibits rat hippocampal neurons via activation of large conductance calcium-activated K+ channels

Shanley, L. J., Irving, A. J., Rae, M. G., Ashford, M. L. J. & Harvey, J., Apr 2002, In : Nature Neuroscience. 5, 4, p. 299-300 2 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
KATP Channels
Leptin
Large-Conductance Calcium-Activated Potassium Channels
Neurons
2001
261 Citations (Scopus)

Leptin enhances NMDA receptor function and modulates hippocampal synaptic plasticity

Shanley, L. J., Irving, A. J. & Harvey, J., Dec 2001, In : Journal of Neuroscience. 21, 24, p. RC186-1-RC186-6

Research output: Contribution to journalArticle

Neuronal Plasticity
Leptin
N-Methyl-D-Aspartate Receptors
N-Methylaspartate
Synaptic Transmission
2000
127 Citations (Scopus)

Essential role of phosphoinositide 3-kinase in leptin-induced KATP channel activation in the rat CRI-G1 insulinoma cell line

Harvey, J., McKay, N. G., Walker, K. S., Van der Kaay, J., Downes, C. P. & Ashford, M. L. J., 18 Feb 2000, In : Journal of Biological Chemistry. 275, 7, p. 4660-4669 10 p.

Research output: Contribution to journalArticle

KATP Channels
Insulinoma
1-Phosphatidylinositol 4-Kinase
Phosphatidylinositols
Leptin
56 Citations (Scopus)

Leptin activation of ATP-sensitive K+ (KATP) channels in rat CRI-G1 insulinoma cells involves disruption of the actin cytoskeleton

Harvey, J., Hardy, S. C., Irving, A. J. & Ashford, M. L. J., 2000, In : Journal of Physiology. 527, 1, p. 95-107 13 p.

Research output: Contribution to journalArticle

KATP Channels
Insulinoma
Leptin
Actin Cytoskeleton
Adenosine Triphosphate
1999
23 Citations (Scopus)
KATP Channels
Sodium Azide
Insulinoma
Oligomycins
Rotenone
1998
8 Citations (Scopus)
Diazoxide
Insulin-Secreting Cells
Leptin
KATP Channels
Cell Line
26 Citations (Scopus)

Insulin occludes leptin activation of ATP-sensitive K+ channels in rat CRI-G1 insulin secreting cells

Harvey, J. & Ashford, M. L. J., 15 Sep 1998, In : Journal of Physiology. 511 , 3, p. 695-706 12 p.

Research output: Contribution to journalArticle

Insulin-Secreting Cells
Leptin
KATP Channels
Adenosine Triphosphate
Insulin
32 Citations (Scopus)
Insulinoma
KATP Channels
Leptin
Tyrosine
Adenosine Triphosphate