Foerster, John

Dr

  • United Kingdom

  • 740 Citations
  • 14 h-Index
20012019
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Research Output 2001 2019

2019
52 Downloads (Pure)

Feasibility Analysis of Interleukin-13 as a Target for a Therapeutic Vaccine

Foerster, J. & Molęda, A., Mar 2019, In : NPJ Vaccines. 7, 1, p. 1-13 13 p., 20.

Research output: Contribution to journalReview article

Open Access
File
Interleukin-13
Vaccines
Therapeutics
Interleukin-4
Safety
Phototherapy
Cost Savings
Psoriasis
Pharmaceutical Preparations
Costs and Cost Analysis
2018
14 Downloads (Pure)

Candidate long-range regulatory sites acting on the IL17-pathway genes TRAF3IP2 and IL17RA are associated with psoriasis

Nititham, J., Fergusson, C., Palmer, C., Liao, W. & Foerster, J., 4 Aug 2018, In : Experimental Dermatology. 27, 11, p. 1294-1297 4 p.

Research output: Contribution to journalArticle

Open Access
File
Psoriasis
Genes
Mutation
Feedback
Sequence Alignment
2 Citations (Scopus)
31 Downloads (Pure)

Narrowband ultraviolet B treatment for psoriasis is highly economical and causes significant savings in cost for topical treatments

Boswell, K., Cameron, H., West, J., Fleming, C., Ibbotson, S., Dawe, R. & Foerster, J., 2 Nov 2018, In : British Journal of Dermatology. 179, 5, p. 1148-1156 9 p.

Research output: Contribution to journalArticle

Open Access
File
Cost Savings
Psoriasis
Health Care Costs
Therapeutics
Drug Prescriptions
2017
10 Citations (Scopus)
126 Downloads (Pure)

HLA-Cw6-positive patients with psoriasis show improved response to methotrexate treatment

West, J., Ogston, S., Berg, J., Palmer, C., Fleming, C., Kumar, V. & Foerster, J., 17 Jul 2017, In : Clinical and Experimental Dermatology. 42, 6, p. 651-655 5 p.

Research output: Contribution to journalArticle

Open Access
File
HLA Antigens
Psoriasis
Methotrexate
Therapeutics
Psoriatic Arthritis
17 Citations (Scopus)
131 Downloads (Pure)

Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer’s and cat allergy

Zeltins, A., West, J., Zabel, F., El-Turabi, A., Jennings, G., Balke, I., Kotecha, A., Stuart, D., Storni, F., Engeroff, P., Maudrich, M., Haas, S., Foerster, J. & Bachmann, M., Oct 2017, In : NPJ Vaccines. 2, p. 1-13 13 p., 30.

Research output: Contribution to journalArticle

Open Access
File
Virus-Like Particle Vaccines
Tetanus
Psoriasis
Epitopes
Hypersensitivity
4 Citations (Scopus)
108 Downloads (Pure)

Narrowband UVB treatment is highly effective and causes a strong reduction in the use of steroid and other creams in psoriasis patients in clinical practice

Foerster, J., Boswell, K., West, J., Cameron, H., Fleming, C., Ibbotson, S. & Dawe, R., 3 Aug 2017, In : PLoS ONE. 12, 8, p. 1-14 14 p., e0181813.

Research output: Contribution to journalArticle

Open Access
File
psoriasis
cream
Psoriasis
steroids
Steroids
1 Citation (Scopus)

Rare diseases and costly treatments: the role of IL-1β in pustular psoriasis

Foerster, J., Jan 2017, In : British Journal of Dermatology. 176, 1, p. 17-18 2 p.

Research output: Contribution to journalComment/debate

2016
7 Citations (Scopus)

Methotrexate in psoriasis under real-world conditions: long-term efficacy and tolerability

West, J., Ogston, S., Palmer, C., Fleming, C., Dawe, R., Kumar, V., Waterston, S. & Foerster, J., Jun 2016, In : British Journal of Dermatology. 174, 6, p. 1407-1410 4 p., 14452.

Research output: Contribution to journalLetter

28 Citations (Scopus)
112 Downloads (Pure)

Safety and efficacy of methotrexate in psoriasis: A meta-analysis of published trials

West, J., Ogston, S. & Foerster, J., 11 May 2016, In : PLoS ONE. 11, 5, e0153740.

Research output: Contribution to journalArticle

Open Access
File
psoriasis
methotrexate
Psoriasis
meta-analysis
Methotrexate
2015
4 Citations (Scopus)

Beyond passive immunization: toward a nanoparticle-based IL-17 vaccine as first in class of future immune treatments

Foerster, J. & Bachman, M., 2015, In : Nanomedicine. 10, 8, p. 1361-1369 9 p.

Research output: Contribution to journalArticle

skin disease
Immunization
genetic research
virus particle
Passive Immunization
2013
9 Citations (Scopus)

An investigation of rheumatoid arthritis loci in patients with early-onset psoriasis validates association of the REL gene

Ali, F. R., Barton, A., Smith, R. L. I., Bowes, J., Flynn, E., Mangino, M., Bataille, V., Foerster, J. P., Worthington, J., Griffiths, C. E. M. & Warren, R. B., Apr 2013, In : British Journal of Dermatology. 168, 4, p. 864-866 3 p.

Research output: Contribution to journalArticle

2012
13 Citations (Scopus)

Protective effect of human endogenous retrovirus K dUTPase variants on psoriasis susceptibility

Lai, O. Y., Chen, H., Michaud, H-A., Hayashi, G., Kuebler, P. J., Hultman, G. K., Ariza, M-E., Williams, M. V., Batista, M. D., Nixon, D. F., Foerster, J., Bowcock, A. M. & Liao, W., 2012, In : Journal of Investigative Dermatology. 132, 7, p. 1833-1840 8 p.

Research output: Contribution to journalArticle

Endogenous Retroviruses
Psoriasis
Haplotypes
Single Nucleotide Polymorphism
Alleles
22 Citations (Scopus)
311 Downloads (Pure)

Skin-targeted inhibition of PPAR β/δ by selective antagonists to treat PPAR β/δ-mediated psoriasis-like skin disease in vivo

Hack, K., Reilly, L., Palmer, C., Read, K., Norval, S., Kime, R., Booth, K. & Foerster, J., May 2012, In : PLoS ONE. 7, 5

Research output: Contribution to journalArticle

Open Access
File
psoriasis
Peroxisome Proliferator-Activated Receptors
skin diseases
Psoriasis
Skin Diseases
10 Citations (Scopus)

Wnt5a inhibits the CpG oligodeoxynucleotide-triggered activation of human plasmacytoid dendritic cells

Hack, K., Reilly, L., Proby, C., Fleming, C., Leigh, I. & Foerster, J., Apr 2012, In : British Journal of Dermatology. 166, 4, p. e36-e36 1 p., P-24.

Research output: Contribution to journalArticle

10 Citations (Scopus)
Oligodeoxyribonucleotides
Dendritic Cells
Interferons
Melanoma
Immunity
41 Citations (Scopus)

Wnt5a is strongly expressed at the leading edge in non-melanoma skin cancer, forming active gradients, while canonical wnt signalling is repressed

Pourreyron, C., Reilly, L., Proby, C., Panteleyev, A., Fleming, C., McLean, K., South, A. P. & Foerster, J., 22 Feb 2012, In : PLoS ONE. 7, 2

Research output: Contribution to journalArticle

Skin Neoplasms
Catenins
Squamous Cell Carcinoma
Skin
squamous cell carcinoma
2011
41 Citations (Scopus)

Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma

Watt, S., Pourreyron, C., Purdie, K., Hogan, C., Cole, C. L., Foster, N., Pratt, N., Bourdon, J-C., Appleyard, V., Murray, K., Thompson, A., Mao, X., Mein, C., Bruckner-Tuderman, L., Evans, A., McGrath, J. A., Proby, C. M., Foerster, J., Leigh, I. & South, A., Nov 2011, In : Oncogene. 30, 46, p. 4666-4677 12 p.

Research output: Contribution to journalArticle

Protein tyrosine phosphatase receptor type delta (PTPRD) stable knockdown leads to increased proliferation in cSCC-derived keratinocytes

Romanowska, M., Lambert, S. R., Foerster, J. P., Purdie, K. J., Harwood, C. A. & Proby, C. M., Sep 2011, In : Journal of Investigative Dermatology. 131, p. S26-S26 1 p.

Research output: Contribution to journalBook/Film/Article review

12 Citations (Scopus)

Proteinuria with fumaric acid ester treatment for psoriasis

Ogilvie, S., Lewis Jones, S., Dawe, R. & Foerster, J., Aug 2011, In : Clinical and Experimental Dermatology. 36, 6, p. 632-634 3 p.

Research output: Contribution to journalArticle

Skin-targeted inhibition of PPAR beta/delta by selective antagonists to treat PPAR beta/delta - mediated psoriasis like skin disease in vivo

Hack, K., Romanowska, M., Reilly, L. & Foerster, J., 11 Apr 2011, In : British Journal of Dermatology. 164, 4, p. 914-914 1 p., O26.

Research output: Contribution to journalBook/Film/Article review

Specific upregulation of non-canonical wnt signalling in non-melanoma skin cancer: Wnt 5a is strongly expressed and controls directional migration

Pourreyron, C., McLean, K., Reilly, L., Proby, C., Panteleyev, A., Evans, A., Leigh, I., South, A. & Foerster, J., Sep 2011, In : Journal of Investigative Dermatology. 131, p. S28-S28 1 p.

Research output: Contribution to journalBook/Film/Article review

STAT3 as a potential substrate for protein tyrosine phosphatase receptor delta (PTPRD) in cutaneous squamous cell carcinoma

Romanowska, M., Lambert, S. R., Purdie, K., McHugh, A., Harwood, C. A., Foerster, J. & Proby, C. M., 11 Apr 2011, In : British Journal of Dermatology. 164, 4, p. 936-936 1 p.

Research output: Contribution to journalBook/Film/Article review

Wnt5a inhibits maturation and interferon alpha production by human plasmacytoid dendritic cells

Hack, K., Proby, C., Fleming, C., Leigh, I., McLean, K., Reilly, L. & Foerster, J., Sep 2011, In : Journal of Investigative Dermatology. 131, p. S91-S91 1 p.

Research output: Contribution to journalBook/Film/Article review

2010

Activation of peroxisome proliferator activator receptor beta/delta in the skin induces IL1 and STAT3 signalling

Romanowska, M., Reilly, L., Palmer, C. & Foerster, J., Apr 2010, In : British Journal of Dermatology. 162, 4, p. 916-917 2 p.

Research output: Contribution to journalSpecial issue

58 Citations (Scopus)

Activation of PPAR beta/delta Causes a Psoriasis-Like Skin Disease In Vivo

Romanowska, M., Reilly, L., Palmer, C. N. A., Gustafsson, M. C. U. & Foerster, J., 16 Mar 2010, In : PLoS ONE. 5, 3, p. - 14 p., e9701.

Research output: Contribution to journalArticle

Activation of wnt5a in epidermis triggers massive hypersensitivity to double-stranded RNA

Reilly, L., Romanowska, M. & Foerster, J., Sep 2010, In : Journal of Investigative Dermatology. 130, S2, p. S84-S84 1 p., 500 [Oral 041].

Research output: Contribution to journalBook/Film/Article review

Identification of polo-like kinase 1 as a potential therapeutic target in squamous cell carcinoma

Watt, S. A., Pourreyron, C., Foerster, J., Hogan, C., Purdie, K., Bruckner-Tuderman, L., Proby, C., McGrath, J. A., Leigh, I. M. & South, A. P., Apr 2010, In : British Journal of Dermatology. 162, 4, p. 923-923 1 p.

Research output: Contribution to journalBook/Film/Article review

Polo-like kinase 1 inhibitors hold potential as targeted therapies for squamous cell carcinoma

Watt, S., Pourreyron, C., Foerster, J., Hogan, C., Purdie, K., Bruckner-Tuderman, L., Proby, C., McGrath, J., Leigh, I. & South, A., Sep 2010, In : Journal of Investigative Dermatology. 130, p. S51-S51 1 p.

Research output: Contribution to journalBook/Film/Article review

Protein tyrosine phosphatase receptor type delta (PTPRD) is expressed in normal and cutaneous squamous cell carcinoma-derived keratinocytes

Romanowska, M., Proby, C. M., Lambert, S. R., Purdie, K., Gulati, A., Leigh, I. M., Harwood, C. A. & Foerster, J., Apr 2010, In : British Journal of Dermatology. 162, 4, p. 945-946 2 p.

Research output: Contribution to journalBook/Film/Article review

Targeted inducible expression of wnt5a in adult mouse epidermis

Reilly, L., Romanowska, M. & Foerster, J., Apr 2010, In : Journal of Investigative Dermatology. 130, s1, p. S96-S96 1 p., 575.

Research output: Contribution to journalBook/Film/Article review

Triggering of psoriasis-like disease by PPAR beta/delta in the epidermis involves activation of STAT3.

Romanowska, M., Reilly, L., Palmer, C. N. & Foerster, J. N., Apr 2010, In : Journal of Investigative Dermatology. 130, S1, p. S13-S13 1 p.

Research output: Contribution to journalSpecial issue

2009

Activation of PPAR delta in vivo is sufficient to cause psoriasis-like disease and replicates transcriptional dysregulation

Romanowska, M., Palmer, C. N. & Foerster, J. P., Apr 2009, In : British Journal of Dermatology. 160, 4, p. 902-903 2 p.

Research output: Contribution to journalBook/Film/Article review

Activation of PPAR delta in vivo replicates major elements of psoriasis

Romanowska, M., Reilly, L., Palmer, C. & Foerster, J., Sep 2009, In : Journal of Investigative Dermatology. 129, s2, p. S89-S89 1 p.

Research output: Contribution to journalSpecial issue

DUSP23, SLCO1B3, SNURF, SNRPN and TJAP1 are genes with differential expression in squamous cell carcinoma keratinocytes derived from patients with recessive dystrophic epidermolysis bullosa

Cole, C. L., Foerster, J., Pourreyron, C., Purdie, K., Hogan, C., Proby, C., Bruckner-Tuderman, L., McGrath, J. A., Leigh, I. M. & South, A. P., Apr 2009, In : British Journal of Dermatology. 160, 4, p. 906-906 1 p.

Research output: Contribution to journalBook/Film/Article review

Quiescent cultured keratinocytes derived from squamous cell carcinoma retain a cancer-specific gene expression signature capable of differentiating squamous cell carcinoma from normal skin in vivo

Pourreyron, C., Foerster, J., Hogan, C., Purdie, K., Bruckner-Tuderman, L., Proby, C., McGrath, J. A., Leigh, I. M. & South, A. P., Sep 2009, In : Journal of Investigative Dermatology. 129, p. S73-S73 1 p., 426[Oral077].

Research output: Contribution to journalBook/Film/Article review

SLCO1B3 expression in recessive dystrophic epidermolysis bullosa associated squamous cell carcinoma is reduced by recombinant type VII collagen

Cole, C. L., Pourreyron, C., Foerster, J., Purdie, K., Salas-Alanis, J. C., Murrell, D. F., Bruckner-Tuderman, L., McGrath, J. A., Leigh, I. M. & South, A. P., Sep 2009, In : Journal of Investigative Dermatology. 129, p. S57-S57 1 p., 325.

Research output: Contribution to journalBook/Film/Article review

Th17 dependent psoriasis-like skin disease in transgenic mice upon activation of PPAR delta

Romanowska, M., Palmer, C. N. & Foerster, J., Apr 2009, In : Journal of Investigative Dermatology. 129, S1, p. S16-S16 1 p.

Research output: Contribution to journalSpecial issue

Wnt5a causes hypersensitivity toward type 1 interferon and is aberrantly distributed in psoriasis

Romanowska, M., Donandt, S., Evans, A., Kellock, D. B., Bray, S. E., McLean, K. & Foerster, J. P., Apr 2009, In : Journal of Investigative Dermatology. 129, S1, p. S16-S16 1 p., 94.

Research output: Contribution to journalBook/Film/Article review

39 Citations (Scopus)

Wnt5a Exhibits Layer-Specific Expression in Adult Skin, Is Upregulated in Psoriasis, and Synergizes with Type 1 Interferon

Romanowska, M., Evans, A., Kellock, D., Bray, S. E., McLean, K., Donandt, S. & Foerster, J., 28 Apr 2009, In : PLoS ONE. 4, 4, p. - 10 p., e5354.

Research output: Contribution to journalArticle

2008

Activation of PPAR delta causes a psoriasis-like skin disease in vivo

Romanowska, M., Niteshwaran, S., Palmer, C. & Foerster, J., Dec 2008, In : British Journal of Dermatology. 159, 6, p. 1398-1398 1 p.

Research output: Contribution to journalBook/Film/Article review

Gene expression profiling of cultured squamous cell carcinoma keratinocytes identifies a pattern of gene expression which predicts invasive capacity

South, A. P., Pourreyron, C., Foerster, J., Mao, X., Purdie, K., Hogan, C., Mein, C., Bruckner-Tuderman, L., Proby, C. M., Young, B., Kelsell, D. P., McGrath, J. A. & Leigh, I. M., Apr 2008, In : British Journal of Dermatology. 158, 4, p. 883-883 1 p.

Research output: Contribution to journalBook/Film/Article review

Identification of genomic and epi-genomic lesions in squamous cell carcinomas using expression profiling of quiescent cultured keratinocytes

Pourreyron, C., Foerster, J., Mao, X., Purdie, K., Bruckner-Tuderman, L., Proby, C., McGrath, J., Leigh, I. & South, A., Apr 2008, In : Journal of Investigative Dermatology. 128, p. S36-S36 1 p.

Research output: Contribution to journalBook/Film/Article review

69 Citations (Scopus)

PPAR delta enhances keratinocyte proliferation in psoriasis and induces heparin-binding EGF-like growth factor

Romanowska, M., Al Yacoub, N., Seidel, H., Donandt, S., Gerken, H., Phillip, S., Haritonova, N., Artuc, M., Schweiger, S., Sterry, W. & Foerster, J., Jan 2008, In : Journal of Investigative Dermatology. 128, 1, p. 110-124 15 p.

Research output: Contribution to journalArticle

PPAR delta
Keratinocytes
Psoriasis
Chemical activation
Skin
23 Citations (Scopus)

PPAR delta is a type 1 IFN target gene and inhibits apoptosis in T cells

al Yacoub, N., Romanowska, M., Krauss, S., Schweiger, S. & Foerster, J., Aug 2008, In : Journal of Investigative Dermatology. 128, 8, p. 1940-1949 10 p.

Research output: Contribution to journalArticle

PPAR delta is a type 1 interferon target gene and inhibits apoptosis in T cells

al Yacoub, N., Romanowska, M., Krauss, S., Schweiger, S. & Foerster, J. P., Apr 2008, In : Journal of Investigative Dermatology. 128, p. S18-S18 1 p., 104.

Research output: Contribution to journalBook/Film/Article review

30 Citations (Scopus)

Protein phosphatase 2A and rapamycin regulate the nuclear localization and activity of the transcription factor GLI3

Krauss, S., Foerster, J., Schneider, R. & Schweiger, S., 15 Jun 2008, In : Cancer Research. 68, 12, p. 4658-4665 8 p.

Research output: Contribution to journalArticle

2005
27 Citations (Scopus)

Haplotype sharing analysis identifies a retroviral dUTPase as candidate susceptibility gene for psoriasis

Foerster, J., Nolte, I., Junge, J., Bruinenberg, M., Schweiger, S., Spaar, K., van der Steege, G., Ehlert, C., Mulder, M., Kalscheuer, V., Blumenthal-Barby, E., Winter, J., Seeman, P., Stander, M., Sterry, W. & te Meerman, G., Jan 2005, In : Journal of Investigative Dermatology. 124, 1, p. 99-102 4 p.

Research output: Contribution to journalArticle

Endogenous Retroviruses
Psoriasis
Haplotypes
Genes
HLA Antigens
10 Citations (Scopus)

Infrared-mediated hyperthermia is effective in the treatment of scleroderma-associated Raynaud's phenomenon

Foerster, J., Fleischanderl, S., Wittstock, S., Storch, A., Meffert, H., Riemekasten, G. & Worm, M., Dec 2005, In : Journal of Investigative Dermatology. 125, 6, p. 1313-1316 4 p.

Research output: Contribution to journalLetter

Raynaud Disease
Fever
Infrared radiation
Rewarming
Arthralgia