Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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MRC QQR 2024-29
Alessi, D. (Investigator), Davies, P. (Investigator), Ganley, I. (Investigator), Kulathu, Y. (Investigator), Liang, A. (Investigator), Rouse, J. (Investigator), Sapkota, G. (Investigator), Swamy, M. (Investigator), Swatek, K. (Investigator) & Virdee, S. (Investigator)
Project: Research
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Characterization of physiological substrates of the NEK1-C21ORF2 complex, and the impact of ALS-causing mutations (joint with Centre for Clinical Brain Sciences, University of Edinburgh)
Rouse, J. (Investigator)
1/11/21 → 31/08/24
Project: Research
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DNA Interstrand Crosslink Repair and Chromatin Remodelling (ICL CHROM)
Rouse, J. (Investigator)
COMMISSION OF THE EUROPEAN COMMUNITIES
1/02/20 → 26/04/22
Project: Research
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Processing of Branched DNA Molecules During Cytokinesis, Uncovering New Mechanisms of Genome Maintenance
Gartner, A. (Investigator), Lilley, D. (Investigator) & Rouse, J. (Investigator)
Biotechnology and Biological Sciences Research Council
1/12/18 → 30/06/22
Project: Research
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MRC QQR
Alessi, D. (Investigator), Davies, P. (Investigator), Ganley, I. (Investigator), Kulathu, Y. (Investigator), Labib, K. (Investigator), Liang, A. (Investigator), Rouse, J. (Investigator), Rousseau, A. (Investigator), Sapkota, G. (Investigator), Virdee, S. (Investigator) & Walden, H. (Investigator)
1/04/18 → 1/04/24
Project: Research
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Functional dissection of the conserved C. elegans LEM-3/ANKLE1 nuclease reveals a crucial requirement for the LEM-like and GIY-YIG domains for DNA bridge processing
Song, J., Geary, P., Salemova, K., Rouse, J., Hong, Y., Rolland, S. G. M. (Lead / Corresponding author) & Gartner, A. (Lead / Corresponding author), 11 Apr 2025, In: Nucleic Acids Research. 53, 6, 18 p., gkaf265.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Downloads (Pure) -
Chemo-phosphoproteomic profiling with ATR inhibitors berzosertib and gartisertib uncovers new biomarkers and DNA damage response regulators
Jadav, R., Weiland, F., Noordermeer, S. M., Carroll, T., Gao, Y., Wang, J., Zhou, H., Lamoliatte, F., Toth, R., Macartney, T., Brown, F., Hastie, J., Alabert, C., van Attikum, H., Zenke, F., Masson, J.-Y. & Rouse, J. (Lead / Corresponding author), Aug 2024, In: Molecular & Cellular Proteomics. 23, 8, 100802.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)37 Downloads (Pure) -
PROTAC-mediated conditional degradation of the WRN helicase as a potential strategy for selective killing of cancer cells with microsatellite instability
Tejwani, V., Carroll, T., Macartney, T., Bandau, S., Alabert, C., Saredi, G., Toth, R. & Rouse, J., 6 Sept 2024, In: Scientific Reports. 14, 16 p., 20824.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)99 Downloads (Pure) -
The histone chaperone SPT2 regulates chromatin structure and function in Metazoa
Saredi, G. (Lead / Corresponding author), Carelli, F. N., Rolland, S. G. M., Furlan, G., Piquet, S., Appert, A., Sanchez-Pulido, L., Price, J. L., Alcon, P., Lampersberger, L., Déclais, A.-C., Ramakrishna, N. B., Toth, R., Macartney, T., Alabert, C., Ponting, C. P., Polo, S. E., Miska, E. A., Gartner, A. & Ahringer, J. & 1 others, , Mar 2024, In: Nature Structural & Molecular Biology. 31, 3, p. 523-535 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile92 Downloads (Pure) -
Functional characterization of C21ORF2 association with the NEK1 kinase mutated in human in diseases
Gregorczyk, M., Pastore, G., Muñoz, I., Carroll, T., Streubel, J., Munro, M., Lis, P., Lange, S., Lamoliatte, F., Macartney, T., Toth, R., Brown, F., Hastie, J., Pereira, G., Durocher, D. & Rouse, J. (Lead / Corresponding author), Jul 2023, In: Life Science Alliance. 6, 7, 19 p., e202201740.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)189 Downloads (Pure)
Activities
- 1 Public engagement and outreach - public lecture/debate/seminar
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Discovery Days 2012
Downes, P. (Chair), Urch, J. (Organiser), Ker, J. (Presenter), Roslender, R. (Presenter), Jindal-Snape, D. (Presenter), Parkes, S. (Presenter), Connell, J. (Chair), Rouse, J. (Presenter), Sani, F. (Presenter), Baldwin, J. (Presenter), Whatley, C. (Chair), Dawson, T. (Presenter), Wilkinson, C. (Presenter), Jones, M. (Presenter), Inns, T. (Chair), McGuigan, A. (Presenter), Hector, M. (Presenter), Jones, R. (Presenter), Ferguson, M. (Chair), Bekker, P. (Presenter), Newman, T. (Presenter), Smith, B. (Presenter), Whitehorn, M. (Presenter), Miller, D. (Presenter) & Black, S. (Presenter)
12 Jan 2012 → 13 Jan 2012Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar