Research Output per year
Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 44 Similar Profiles
Chagas Disease
Medicine & Life Sciences
Trypanosoma cruzi
Medicine & Life Sciences
Parasites
Medicine & Life Sciences
Drug Discovery
Medicine & Life Sciences
Leishmania donovani
Medicine & Life Sciences
Methionine-tRNA Ligase
Medicine & Life Sciences
Nifurtimox
Medicine & Life Sciences
Triazoles
Medicine & Life Sciences
Network
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Research Output 2016 2018
- 45 Citations
- 4 h-Index
- 9 Article
2,4-Diamino-6-methylpyrimidines for the potential treatment of Chagas’ disease
Thomas, M. G., De Rycker, M., Cotillo Torrejon, I., Thomas, J., Riley, J., Spinks, D., Read, K. D., Miles, T. J., Gilbert, I. H. & Wyatt, P. G., 1 Oct 2018, In : Bioorganic & Medicinal Chemistry Letters. 28, 18, p. 3025-3030 6 p.Research output: Contribution to journal › Article
Chagas Disease
Parasites
Nifurtimox
Trypanosoma cruzi
Screening
Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas’ disease drug discovery
MacLean, L., Thomas, J., Lewis, M. D., Cotillo, I., Gray, D. & De Rycker, M., 12 Jul 2018, In : PLoS Neglected Tropical Diseases. 12, 7, p. 1-22 22 p., e0006612.Research output: Contribution to journal › Article
Open Access
File
Chagas Disease
Trypanosoma cruzi
Drug Discovery
Parasites
Ergosterol
Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis
Thomas, M. G., De Rycker, M., Ajakane, M., Albrecht, S., Álvarez-Pedraglio, A. I., Boesche, M., Brand, S., Campbell, L., Cantizani-Perez, J., Cleghorn, L. A. T., Copley, R. C. B., Crouch, S. D., Daugan, A., Drewes, G., Ferrer, S., Ghidelli-Disse, S., Gonzalez, S., Gresham, S. L., Hill, A. P., Hindley, S. J. & 32 others , 20 Dec 2018, In : Journal of Medicinal Chemistry. 23 p.Research output: Contribution to journal › Article
Visceral Leishmaniasis
Leishmania major
Leishmania donovani
Standard of Care
Solubility
Chemical Validation of Methionyl tRNA Synthetase (MetRS) as a Druggable Target in Leishmania donovani
Torrie, L., Brand, S., Robinson, D., Ko, E. J., Stojanovski, L., Simeons, F. R. C., Wyllie, S., Thomas, J., Ellis, L., Osuna-Cabello, M., Epemolu, R., Nuehs, A., Riley, J., MacLean, L., Manthri, S., Read, K., Gilbert, I., Fairlamb, A. & De Rycker, M., Oct 2017, In : ACS Infectious Diseases. 3, 10, p. 718-727 10 p.Research output: Contribution to journal › Article
Open Access
File
Methionine-tRNA Ligase
Leishmania donovani
Leishmania
Methionine
Animal Models
Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi
Brand, S., Ko, E. J., Viayna, E., Thompson, S., Spinks, D., Thomas, M., Sandberg, L., Francisco, A. F., Jayawardhana, S., Smith, V. C., Jansen, C., De Rycker, M., Thomas, J., MacLean, L., Osuna-Cabello, M., Riley, J., Scullion, P., Stojanovski, L., Simeons, F. R. C., Epemolu, O. & 16 others , 14 Sep 2017, In : Journal of Medicinal Chemistry. 60, 17, p. 7284-7299 16 p.Research output: Contribution to journal › Article
Open Access
File
Triazoles
Trypanosoma cruzi
Parasites
Chagas Disease
Nifurtimox