Research Output per year
Fingerprint Dive into the research topics where John Thomas is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 43 Similar Profiles
Chagas Disease
Medicine & Life Sciences
Trypanosoma cruzi
Medicine & Life Sciences
Parasites
Medicine & Life Sciences
Leishmania donovani
Medicine & Life Sciences
Visceral Leishmaniasis
Medicine & Life Sciences
Drug Discovery
Medicine & Life Sciences
Methionine-tRNA Ligase
Medicine & Life Sciences
Nifurtimox
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 2016 2019
- 81 Citations
- 6 h-Index
- 10 Article
4
Citations
(Scopus)
Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis
Thomas, M. G., De Rycker, M., Ajakane, M., Albrecht, S., Álvarez-Pedraglio, A. I., Boesche, M., Brand, S., Campbell, L., Cantizani-Perez, J., Cleghorn, L. A. T., Copley, R. C. B., Crouch, S. D., Daugan, A., Drewes, G., Ferrer, S., Ghidelli-Disse, S., Gonzalez, S., Gresham, S. L., Hill, A. P., Hindley, S. J. & 32 others, , 14 Feb 2019, In : Journal of Medicinal Chemistry. 62, 3, p. 1180-1202 23 p.Research output: Contribution to journal › Article
Visceral Leishmaniasis
Leishmania major
Leishmania donovani
Standard of Care
Solubility
7
Citations
(Scopus)
84
Downloads
(Pure)
Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition
Wyllie, S., Brand, S., Thomas, M., De Rycker, M., Chung, C-W., Peña, I., Bingham, R., Bueren-Calabuig, J., Cantizani, J., Cebrian, D., Craggs, P. D., Ferguson, L., Goswami, P., Hobrath, J., Howe, J., Jeacock, L., Ko, E. J., Korczynska, J., MacLean, L., Manthri, S. & 29 others, , 7 May 2019, In : Proceedings of the National Academy of Sciences. 116, 19, p. 9318-9323 6 p., 201820175.Research output: Contribution to journal › Article
Open Access
File
Leishmania infantum
Visceral Leishmaniasis
Proteasome Endopeptidase Complex
Leishmania donovani
Parasites
2,4-Diamino-6-methylpyrimidines for the potential treatment of Chagas’ disease
Thomas, M. G., De Rycker, M., Cotillo Torrejon, I., Thomas, J., Riley, J., Spinks, D., Read, K. D., Miles, T. J., Gilbert, I. H. & Wyatt, P. G., 1 Oct 2018, In : Bioorganic & Medicinal Chemistry Letters. 28, 18, p. 3025-3030 6 p.Research output: Contribution to journal › Article
Open Access
File
Chagas Disease
Parasites
Nifurtimox
Trypanosoma cruzi
Screening
11
Citations
(Scopus)
93
Downloads
(Pure)
Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas’ disease drug discovery
MacLean, L., Thomas, J., Lewis, M. D., Cotillo, I., Gray, D. & De Rycker, M., 12 Jul 2018, In : PLoS Neglected Tropical Diseases. 12, 7, p. 1-22 22 p., e0006612.Research output: Contribution to journal › Article
Open Access
File
Chagas Disease
Trypanosoma cruzi
Drug Discovery
Parasites
Ergosterol
4
Citations
(Scopus)
129
Downloads
(Pure)
Chemical Validation of Methionyl tRNA Synthetase (MetRS) as a Druggable Target in Leishmania donovani
Torrie, L., Brand, S., Robinson, D., Ko, E. J., Stojanovski, L., Simeons, F. R. C., Wyllie, S., Thomas, J., Ellis, L., Osuna-Cabello, M., Epemolu, R., Nuehs, A., Riley, J., MacLean, L., Manthri, S., Read, K., Gilbert, I., Fairlamb, A. & De Rycker, M., Oct 2017, In : ACS Infectious Diseases. 3, 10, p. 718-727 10 p.Research output: Contribution to journal › Article
Open Access
File
Methionine-tRNA Ligase
Leishmania donovani
Leishmania
Methionine
Animal Models