• 2098 Citations
  • 26 h-Index
1985 …2016

Research output per year

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Research Output

2016

The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway

Bailly, A., Perrin, A., Bou Malhab, L. J., Pion, E., Larance, M., Nagala, M., Smith, P., O'Donohue, M-F., Gleizes, P-E., Zomerdijk, J., Lamond, A. I. & Xirodimas, D. P., 28 Jan 2016, In : Oncogene. 35, 4, p. 415-426 12 p.

Research output: Contribution to journalArticle

Open Access
File
23 Citations (Scopus)
306 Downloads (Pure)
2013

Structural biology: Pivotal findings for a transcription machine

Zomerdijk, J., 2013, In : Nature. 502, 7473, p. 629-630 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Structural biology: Pivotal findings for a transcription machine

Zomerdijk, J., 31 Oct 2013, In : Nature. 502, 7473, p. 629-630 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Topoisomerase IIα promotes activation of RNA polymerase i transcription by facilitating pre-initiation complex formation

Ray, S., Panova, T., Miller, G., Volkov, A., Porter, A. C. G., Russell, J., Panov, K. I. & Zomerdijk, J. C. B. M., 19 Mar 2013, In : Nature Communications. 4, 1598.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2011

RNA polymerase I-specific subunits promote polymerase clustering to enhance the rRNA gene transcription cycle

Albert, B., Leger-Silvestre, I., Normand, C., Ostermaier, M. K., Perez-Fernandez, J., Panov, K. I., Zomerdijk, J. C. B. M., Schultz, P. & Gadal, O., 24 Jan 2011, In : Journal of Cell Biology. 192, 2, p. 277-293 17 p.

Research output: Contribution to journalArticle

Open Access
File
41 Citations (Scopus)
462 Downloads (Pure)

TAF1B Is a TFIIB-Like Component of the Basal Transcription Machinery for RNA Polymerase I

Naidu, S., Friedrich, J. K., Russell, J. & Zomerdijk, J. C. B. M., 16 Sep 2011, In : Science. 333, 6049, p. 1640-1642 3 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2009

FACT facilitates chromatin transcription by RNA polymerases I and III

Birch, J. L., Tan, B. C-M., Panov, K. I., Panova, T. B., Andersen, J. S., Owen-Hughes, T. A., Russell, J., Lee, S-C. & Zomerdijk, J. C. B. M., 8 Apr 2009, In : EMBO Journal. 28, 7, p. 854-865 12 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)
2008

Structure and function of ribosomal RNA gene chromatin

Birch, J. L. & Zomerdijk, J. C. B. M., Aug 2008, In : Biochemical Society Transactions. 36, p. 619-624 6 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2007

A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription

Gorski, J. J., Pathak, S., Panov, K., Kasciukovic, T., Panova, T., Russell, J. & Zomerdijk, J. C. B. M., Mar 2007, In : The EMBO Journal. 26, 6, p. 1560-1568 9 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)
2006

Casein kinase 2 associates with initiation-competent RNA polymerase I and has multiple roles in ribosomal DNA transcription

Panova, T. B., Panov, K. I., Russell, J. & Zomerdijk, J. C. B. M., 2006, In : Molecular and Cellular Biology. 26, 16, p. 5957-5968 12 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

RNA polymerase I-specific subunit CAST/hPAF49 has a role in the activation of transcription by upstream binding factor

Panov, K. I., Panova, T. B., Gadal, O., Nishiyama, K., Saito, T., Russell, J. & Zomerdijk, J. C. B. M., Jul 2006, In : Molecular and Cellular Biology. 26, 14, p. 5436-5448 13 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

The RNA polymerase I transcription machinery

Russell, J. & Zomerdijk, J. C. B. M., 2006, Transcription: papers from the Biochemical Society symposium no. 73, held at Imperial College, London, April 2005. Roberts, S., Weinzierl, R. & White, R. (eds.). London: Portland Press, p. 203-216 14 p. (Biochemical Society symposia; vol. 73).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

95 Citations (Scopus)

UBF activates RNA polymerase I transcription by stimulating promoter escape

Panov, K. I., Friedrich, J. K., Russell, J. & Zomerdijk, J. C. B. M., 2006, In : The EMBO Journal. 25, 14, p. 3310-3322 13 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)
2005

RNA-polymerase-I-directed rDNA transcription, life and works

Russell, J. & Zomerdijk, J. C. B. M., 2005, In : Trends in Biochemical Sciences. 30, 2, p. 87-96 10 p.

Research output: Contribution to journalArticle

194 Citations (Scopus)

TBP-TAF complex SL1 directs RNA polymerase I pre-initiation complex formation and stabilizes upstream binding factor at the rDNA promoter

Friedrich, J. K., Panov, K. I., Cabart, P., Russell, J. & Zomerdijk, J. C. B. M., 2005, In : Journal of Biological Chemistry. 280, 33, p. 29551-29558 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

The RNA polymerase I transcription machinery

Russell, J. & Zomerdijk, J. C. B. M., 2005.

Research output: Contribution to conferencePaper

143 Citations (Scopus)
2004
85 Citations (Scopus)

Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells

Leung, A. K. L., Gerlich, D., Miller, G., Lyon, C., Lam, Y. W., Lleres, D., Daigle, N., Zomerdijk, J., Ellenherg, J. & Lamond, A. I., 2004, In : Journal of Cell Biology. 166, 6, p. 787-800 14 p.

Research output: Contribution to journalArticle

120 Citations (Scopus)
2001
45 Citations (Scopus)

hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters

Miller, G., Panov, K. I., Friedrich, J. K., Trinkle-Mulcahy, L., Lamond, A. I. & Zomerdijk, J. C. B. M., Mar 2001, In : The EMBO Journal. 20, 6, p. 1373-1382 10 p.

Research output: Contribution to journalArticle

133 Citations (Scopus)
2000

Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry

Ajuh, P., Kuster, B., Panov, K., Zomerdijk, J. C. B. M., Mann, M. & Lamond, A. I., 2000, In : EMBO Journal. 19, 23, p. 6569-6581 13 p.

Research output: Contribution to journalArticle

150 Citations (Scopus)
1998

Subnuclear localization of the active variant surface glycoprotein gene expression site in Trypanosoma brucei

Chaves, I., Zomerdijk, J., Dirks-Mulder, A., Dirks, R. W., Raap, A. K. & Borst, P., 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 21, p. 12328-12333 6 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)
1994

Assembly of transcriptionally active RNA polymerase I initiation factor SL1 from recombinant subunits

Zomerdijk, J. C., Beckmann, H., Comai, L. & Tjian, R., 1994, In : Science. 266, 5193, p. 2015-2018 4 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits

Comai, L. ., Zomerdijk, J. C., Beckmann, H., Zhou, S., Admon, A. & Tjian, R., 1994, In : Science. 266, 5193, p. 1966-1972 7 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)
1992

A ribosomal RNA gene promoter at the telomere of a mini-chromosome in Trypanosoma brucei

Zomerdijk, J. C. B. M., Kieft, R. & Borst, P., 1992, In : Nucleic Acids Research. 20, 11, p. 2725-2734 10 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
1991
94 Citations (Scopus)

Antigenic variation in Trypanosoma brucei: a telomeric expression site for variant-specific surface glycoprotein genes with novel features

Zomerdijk, J. C. B. M., Kieft, R., Duyndam, M., Shiels, P. G. & Borst, P., 1991, In : Nucleic Acids Research. 19, 7, p. 1359-1368 10 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Efficient production of functional mRNA mediated by RNA polymerase I in Trypanosoma brucei

Zomerdijk, J. C. B. M., Kieft, R. & Borst, P., 1991, In : Nature. 353, 6346, p. 772-775 4 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)
1990

Control of surface antigen genes in African trypanosomes

Borst, P., Gommersampt, J. H., Lutgerink, J., Ouellette, M., Ten Asbroek, A. L. M. A. & Zomerdijk, J. C. B. M., 1990, In : Biochemical Society Transactions. 18, 5, p. 741-742 2 p.

Research output: Contribution to journalArticle

Control of surface antigen genes in African trypanosomes

Borst, P., Gommersampt, J. H., Lutgerink, J., Ouellette, M., Ten Asbroek, A. L. M. A. & Zomerdijk, J. C. B. M., 1990.

Research output: Contribution to conferencePaper

Control of variant-specific surface glycoprotein expression sites in Trypanosoma-brucei

Borst, P., Zomerdijk, J., Ouellette, M., Crozatier, M. & Ten Asbroek, A., 1990, Parasites, molecular biology, drug and vaccine design : proceedings of a UCLA Symposium held at Keystone, Colorado, April 3-10, 1989. Agabian, N. & Cerami, A. (eds.). New York: Wiley-Liss, p. 59-72 14 p. (UCLA symposia on molecular and cellular biology - new series; vol. 130).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei

Zomerdijk, J. C. B. M., Ouellette, M., ten Asbroek, A. L. M. A., Kieft, R., Bommer, A. M. M., Clayton, C. E. & Borst, P., 1990, In : EMBO Journal. 9, 9, p. 2791-2801 11 p.

Research output: Contribution to journalArticle

1989

Control of variant-specific surface glycoprotein expression sites in Trypanosoma-brucei

Borst, P., Zomerdijk, J., Ouellette, M., Crozatier, M. & Ten Asbroek, A., 1989.

Research output: Contribution to conferencePaper

1987

In vivo labelling of intermediates in the discontinuous synthesis of mRNAs in Trypanosoma brucei

Laird, P. W., Zomerdijk, J. C. B. M., de Korte, D. & Borst, P., 1987, In : EMBO Journal. 6, 4, p. 1055-1062 8 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Transsplicing in Trypansomes

Laird, P. W., Zomerdijk, J. C. B. M. & Borst, P., 1987.

Research output: Contribution to conferencePoster

Transsplicing in Trypansomes

Laird, P. W., Zomerdijk, J. C. B. M. & Borst, P., 1987, In : Journal of Cellular Biochemistry. 35, Suppl. 11C, p. 54-54 1 p.

Research output: Contribution to journalMeeting abstract

1985

Separation of chromosomal DNA molecules from Saccharomyces cerevisiae

Zomerdijk, J. C. B. M., de Jonge, P. & Steensma, H. Y., 1985, In : Antonie van Leeuwenhoek : Journal of Microbiology. 51, 5-6, p. 564-565 2 p.

Research output: Contribution to journalMeeting abstract