Hobrath, Judith

Dr

  • 66 Citations
  • 4 h-Index
20162019
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  • 1 Similar Profiles
shikimate kinase Medicine & Life Sciences
Sulindac Medicine & Life Sciences
Amides Medicine & Life Sciences
Mycobacterium tuberculosis Medicine & Life Sciences
Fenamates Medicine & Life Sciences
Screening Chemical Compounds
Anti-Inflammatory Agents Medicine & Life Sciences
Libraries Medicine & Life Sciences

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Research Output 2016 2019

  • 66 Citations
  • 4 h-Index
  • 10 Article
  • 1 Review article
1 Citation (Scopus)
27 Downloads (Pure)

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Wyllie, S., Brand, S., Thomas, M., De Rycker, M., Chung, C-W., Peña, I., Bingham, R., Bueren-Calabuig, J., Cantizani, J., Cebrian, D., Craggs, P. D., Ferguson, L., Goswami, P., Hobrath, J., Howe, J., Jeacock, L., Ko, E. J., Korczynska, J., MacLean, L., Manthri, S. & 29 othersSantos Martinez, M., Mata-Cantero, L., Moniz, S., Nuhs, A., Osuna-Cabello, M., Pinto, E., Riley, J., Robinson, S., Rowland, P., Simeons, F., Shishikura, Y., Spinks, D., Stojanovski, L., Thomas, J., Thompson, S., Viayna Gaza, E., Wall, R., Zuccotto, F., Horn, D., Ferguson, M., Fairlamb, A., Fiandor, J. M., Martín, J., Gray, D., Miles, T. J., Gilbert, I., Read, K., Marco, M. & Wyatt, P., 7 May 2019, In : Proceedings of the National Academy of Sciences. 116, 19, p. 9318-9323 6 p., 201820175.

Research output: Contribution to journalArticle

Open Access
File
Leishmania infantum
Visceral Leishmaniasis
Proteasome Endopeptidase Complex
Leishmania donovani
Parasites
55 Downloads (Pure)

Amine Containing Analogs of Sulindac for Cancer Prevention

Mathew, B., Hobrath, J. V., Connelly, M. C., Guy, R. K. & Reynolds, R. C., 31 Jan 2018, In : Open Medicinal Chemistry Journal. 12, p. 1-12 12 p.

Research output: Contribution to journalArticle

Open Access
File
Sulindac
Amines
Libraries
Neoplasms
Adenomatous Polyps
2 Citations (Scopus)
37 Downloads (Pure)

A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase

Alturki, M. S., Fuanta, N. R., Jarrard, M. A., Hobrath, J. V., Goodwin, D. C., Rants'o, T. A. & Calderón, A. I., 15 Feb 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 4, p. 802-808 7 p.

Research output: Contribution to journalArticle

Open Access
File
shikimate kinase
Enzyme inhibition
Mycobacterium tuberculosis
Assays
Screening
1 Citation (Scopus)
39 Downloads (Pure)

Mechanism of irreversible inhibition of Mycobacterium tuberculosis shikimate kinase by ilimaquinone

Simithy, J., Fuanta, N. R., Hobrath, J. V., Kochanowska-Karamyan, A., Hamann, M. T., Goodwin, D. C. & Calderón, A. I., May 2018, In : Biochimica et Biophysica Acta: General Subjects. 1866, 5-6, p. 731-739 9 p.

Research output: Contribution to journalArticle

Open Access
File
shikimate kinase
Mycobacterium tuberculosis
ilimaquinone
2 Citations (Scopus)
46 Downloads (Pure)

Oxazole and thiazole analogs of sulindac for cancer prevention

Mathew, B., Hobrath, J. V., Connelly, M. C., Guy, R. K. & Reynolds, R. C., Apr 2018, In : Future Medicinal Chemistry. 10, 7, p. 743-753 12 p.

Research output: Contribution to journalArticle

Open Access
File
Oxazoles
Sulindac
Thiazoles
Amides
Colonic Neoplasms