• 11 Citations
  • 2 h-Index
20172018
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Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 27 Similar Profiles
Leishmania mexicana Medicine & Life Sciences
Trypanosoma brucei brucei Medicine & Life Sciences
Trypanosomiasis Medicine & Life Sciences
Clustered Regularly Interspaced Short Palindromic Repeats Medicine & Life Sciences
Guide RNA Medicine & Life Sciences
Transketolase Medicine & Life Sciences
Parasites Medicine & Life Sciences
Gluconeogenesis Medicine & Life Sciences

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Research Output 2017 2018

  • 11 Citations
  • 2 h-Index
  • 4 Article
1 Citations

Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana

Kovářová, J., Pountain, A. W., Wildridge, D., Weidt, S., Bringaud, F., Burchmore, R. J. S., Achcar, F. & Barrett, M. P., 19 Mar 2018, In : PLoS Pathogens. 14, 3, p. 1-30 30 p., e1006953.

Research output: Contribution to journalArticle

Open Access
File
Leishmania mexicana
Transketolase
Virulence
Enzymes
Pentose Phosphate Pathway

Gluconeogenesis using glycerol as a substrate in bloodstream-form Trypanosoma brucei

Kovarova, J., Nagar, R., Correia Faria, J., Ferguson, M., Barrett, M. P. & Horn, D., 27 Dec 2018, In : PLoS Pathogens. 14, 12, p. 1-22 22 p., e1007475.

Research output: Contribution to journalArticle

Open Access
File
Trypanosoma brucei brucei
Gluconeogenesis
Glycerol
Trypanosomiasis
Monosaccharide Transport Proteins
2 Citations

Inducible high-efficiency CRISPR-Cas9-targeted gene editing and precision base editing in African trypanosomes

Rico Vidal, E., Jeacock, L., Kovarova, J. & Horn, D., 21 May 2018, In : Scientific Reports. 8, p. 1-10 10 p., 7960.

Research output: Contribution to journalArticle

Open Access
File
Clustered Regularly Interspaced Short Palindromic Repeats
Guide RNA
Trypanosoma brucei brucei
Trypanosomiasis
Aquaglyceroporins
8 Citations

Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

Mwenechanya, R., Kovářová, J., Dickens, N. J., Manikhandan, M., Herzyk, P., Vincent, I. M., Weidt, S. K., Burgess, K. E., Burchmore, R. J. S., Pountain, A. W., Smith, T. K., Creek, D. J., Kim, D. H., Lepesheva, G. I. & Barrett, M. P., 16 Jun 2017, In : PLoS Neglected Tropical Diseases. 11, 6, p. 1-21 21 p., e0005649.

Research output: Contribution to journalArticle

Open Access
File
Leishmania mexicana
Amphotericin B
Sterols
Mutation
Ergosterol