Harrison, Justin

Dr

  • 254 Citations
  • 9 h-Index
20092020

Research output per year

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Research Output

  • 254 Citations
  • 9 h-Index
  • 11 Article
  • 1 Patent

Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease

Harrison, J. R., Sarkar, S., Hampton, S., Riley, J., Stojanovski, L., Sahlberg, C., Appelqvist, P., Erath, J., Mathan, V., Rodriguez, A., Kaiser, M., Pacanowska, D. G., Read, K. D., Johansson, N. G. & Gilbert, I. H., 26 Mar 2020, In : Journal of Medicinal Chemistry. 63, 6, p. 3066-3089 24 p.

Research output: Contribution to journalArticle

  • PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis

    Wang, Q., Boshoff, H. I. M., Harrison, J. R., Ray, P. C., Green, S. R., Wyatt, P. G. & Barry, C. E., 6 Mar 2020, In : Science. 367, 6482, p. 1147-1151 5 p.

    Research output: Contribution to journalArticle

  • 2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization

    Murugesan, D., Ray, P. C., Bayliss, T., Prosser, G. A., Harrison, J. R., Green, K., Soares De Melo, C., Feng, T. S., Street, L. J., Chibale, K., Warner, D. F., Mizrahi, V., Epemolu, O., Scullion, P., Ellis, L., Riley, J., Shishikura, Y., Ferguson, L., Osuna-Cabello, M., Read, K. D. & 10 others, Green, S. R., Lamprecht, D. A., Steyn, A. J. C., Ioerger, T. R., Sacchettini, J., Rhee, K. Y., Arora, K., Barry, C. E., Wyatt, P. G. & Boshoff, H. I. M., 8 Jun 2018, In : ACS Infectious Diseases. 4, 6, p. 954-969 16 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 10 Citations (Scopus)
    130 Downloads (Pure)

    A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors

    Harrison, J. R., Brand, S., Smith, V., Robinson, D. A., Thompson, S., Smith, A., Davies, K., Mok, N., Torrie, L. S., Collie, I., Hallyburton, I., Norval, S., Simeons, F. R. C., Stojanovski, L., Frearson, J. A., Brenk, R., Wyatt, P. G., Gilbert, I. H. & Read, K. D., 12 Sep 2018, In : Journal of Medicinal Chemistry. 61, 18, p. 8374–8389 16 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 12 Citations (Scopus)
    161 Downloads (Pure)

    Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi

    Herrera, L. J., Brand, S., Santos, A., Nohara, L. L., Harrison, J., Norcross, N. R., Thompson, S., Smith, V., Lema, C., Varela-Ramirez, A., Gilbert, I. H., Almeida, I. C. & Maldonado, R. A., 29 Apr 2016, In : PLoS Neglected Tropical Diseases. 10, 4, 20 p., e0004540.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 15 Citations (Scopus)
    259 Downloads (Pure)