Projects per year
Personal profile
Biography
2006-2013 Senior Group Leader, Paterson Institute for Cancer Research (Cancer Research U.K.), University of Manchester.
2001-2007 Cancer Research U.K. Senior Cancer Research
2006-2013 Senior Group Leader, Paterson Institute for Cancer Research (Cancer Research U.K.), University of Manchester.
2001-2007 Cancer Research U.K. Senior Cancer Research Fellow, Paterson Institute for Cancer Research, University of Manchester.
2001-2006 Junior Group Leader, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, University of Manchester.
1997-2001 Post-doctoral fellowship from the ICRF to work with John Diffley, Clare Hall research laboratories, London.
1995-1997 Post-doctoral fellow with Stephen Kearsey, Department of Zoology, University of Oxford.
1993-1994 EMBO Long-term fellowship to work with Sergio Moreno, University of Salamanca, Spain
Fellow, Paterson Institute for Cancer Research, University of Manchester.
2001-2006 Junior Group Leader, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, University of Manchester.
1997-2001 Post-doctoral fellowship from the ICRF to work with John Diffley, Clare Hall research laboratories, London.
1995-1997 Post-doctoral fellow with Stephen Kearsey, Department of Zoology, University of Oxford.
1993-1994 EMBO Long-term fellowship to work with Sergio Moreno, University of Salamanca, Spain
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, University of Oxford
Award Date: 1 Jan 1993
Master of Arts, University of Cambridge
Award Date: 1 Jan 1992
Bachelor of Arts, University of Cambridge
Award Date: 1 Jan 1989
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Collaborations and top research areas from the last five years
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Mechanism of Metazoan Replisome Assembly In Health And Disease
Labib, K. (Investigator)
1/04/24 → 31/03/32
Project: Research
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Regulation of Metazoan Replisome Disassembly at Stalled Replication Forks and During Mitosis
Labib, K. (Investigator)
1/09/23 → 31/08/28
Project: Research
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Establishment of Cryo-EM Screening Facility At University Of Dundee (Equipment Grant)
Kulathu, Y. (Investigator), Labib, K. (Investigator), Masson, G. (Investigator), Moraga Gonzalez, I. (Investigator), Murray, D. (Investigator), Owen-Hughes, T. (Investigator), Stanley-Wall, N. (Investigator) & Wyatt, P. (Investigator)
1/12/21 → 31/12/26
Project: Research
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MRC Climate Crisis Network (Lead: University Of Dundee other instns: Mitocondrial Unit, Human Genetics Unit)
Alessi, D. (Investigator) & Labib, K. (Investigator)
1/01/22 → 31/12/24
Project: Research
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MRC QQR
Alessi, D. (Investigator), Davies, P. (Investigator), Ganley, I. (Investigator), Kulathu, Y. (Investigator), Labib, K. (Investigator), Liang, A. (Investigator), Rouse, J. (Investigator), Rousseau, A. (Investigator), Sapkota, G. (Investigator), Virdee, S. (Investigator) & Walden, H. (Investigator)
1/04/18 → 1/04/24
Project: Research
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CMG helicase disassembly is essential and driven by two pathways in budding yeast
Polo Rivera, C., Deegan, T. D. (Lead / Corresponding author) & Labib, K. P. M. (Lead / Corresponding author), 16 Sept 2024, In: The EMBO Journal. 43, 18, p. 3818-3845 28 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)48 Downloads (Pure) -
Mechanism of human PINK1 activation at the TOM complex in a reconstituted system
Raimi, O. G., Ojha, H., Ehses, K., Dederer, V., Lange, S. M., Rivera, C. P., Deegan, T. D., Chen, Y., Wightman, M., Toth, R., Labib, K. P. M., Mathea, S., Ranson, N., Fernández-Busnadiego, R. & Muqit, M. M. K. (Lead / Corresponding author), Jun 2024, In: Science Advances. 10, 23, 16 p., eadn7191.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)86 Downloads (Pure) -
TTF2 drives mitotic replisome disassembly and MiDAS by coupling the TRAIP ubiquitin ligase to Polε
Fujisawa, R. & Labib, K., 2 Dec 2024, BioRxiv, 95 p.Research output: Working paper/Preprint › Preprint
Open Access -
USP37 protects mammalian cells during DNA replication stress by counteracting CUL2LRR1 and TRAIP
Villa, F., Ainsworth, J. & Labib, K. P. M. (Lead / Corresponding author), 3 Sept 2024, BioRxiv, 80 p.Research output: Working paper/Preprint › Preprint
File2 Downloads (Pure) -
DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in Caenorhabditis elegans
Xia, Y., Sonneville, R., Jenkyn-Bedford, M., Ji, L., Alabert, C., Hong, Y. (Lead / Corresponding author), Yeeles, J. T. P. (Lead / Corresponding author) & Labib, K. P. M. (Lead / Corresponding author), 22 Sept 2023, In: Science. 381, 6664, p. eadi4932 30 p., adi4932.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)600 Downloads (Pure)
Prizes
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Fellowship of the Royal Society of Edinburgh
Labib, K. (Recipient), 2016
Prize: Election to learned society
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Long-term Doctoral Fellowship (1993-1994)
Labib, K. (Recipient), 1993
Prize: Fellowship awarded competitively
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Senior Cancer Research Fellowship, 2001-2007
Labib, K. (Recipient), 2001
Prize: Fellowship awarded competitively
Activities
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Invited Seminar (CRUK Manchester Institute, Manchester, U.K.)
Labib, K. (Speaker)
2 Sept 2024Activity: Talk or presentation types › Invited talk
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Invited Seminar (IMB Mainz and Collaborative Research Centre 1361)
Labib, K. (Speaker)
4 Nov 2024Activity: Talk or presentation types › Invited talk
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The Origins of Life (Public Engagement Talk)
Labib, K. (Member)
29 May 2024Activity: Other activity types › Schools engagement
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Invited Seminar, University of Salamanca, Spain
Labib, K. (Speaker)
20 Apr 2023Activity: Talk or presentation types › Invited talk
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Keynote lecture, London Cell Cycle Club
Labib, K. (Speaker)
9 May 2023Activity: Talk or presentation types › Keynote