Projects per year
Personal profile
Biography
2006-2013 Senior Group Leader, Paterson Institute for Cancer Research (Cancer Research U.K.), University of Manchester.
2001-2007 Cancer Research U.K. Senior Cancer Research
2006-2013 Senior Group Leader, Paterson Institute for Cancer Research (Cancer Research U.K.), University of Manchester.
2001-2007 Cancer Research U.K. Senior Cancer Research Fellow, Paterson Institute for Cancer Research, University of Manchester.
2001-2006 Junior Group Leader, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, University of Manchester.
1997-2001 Post-doctoral fellowship from the ICRF to work with John Diffley, Clare Hall research laboratories, London.
1995-1997 Post-doctoral fellow with Stephen Kearsey, Department of Zoology, University of Oxford.
1993-1994 EMBO Long-term fellowship to work with Sergio Moreno, University of Salamanca, Spain
Fellow, Paterson Institute for Cancer Research, University of Manchester.
2001-2006 Junior Group Leader, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, University of Manchester.
1997-2001 Post-doctoral fellowship from the ICRF to work with John Diffley, Clare Hall research laboratories, London.
1995-1997 Post-doctoral fellow with Stephen Kearsey, Department of Zoology, University of Oxford.
1993-1994 EMBO Long-term fellowship to work with Sergio Moreno, University of Salamanca, Spain
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, University of Oxford
Award Date: 1 Jan 1993
Master of Arts, University of Cambridge
Award Date: 1 Jan 1992
Bachelor of Arts, University of Cambridge
Award Date: 1 Jan 1989
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Network
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MRC Climate Crisis Network (Lead: University Of Dundee other instns: Mitocondrial Unit, Human Genetics Unit)
1/01/22 → 31/12/23
Project: Research
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Establishment of Cryo-EM Screening Facility At University Of Dundee (Equipment Grant)
Kulathu, Y., Labib, K., Masson, G., Moraga Gonzalez, I., Murray, D., Owen-Hughes, T., Stanley-Wall, N. & Wyatt, P.
1/12/21 → 31/12/26
Project: Research
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MRC QQR
Alessi, D., Davies, P., Ganley, I., Kulathu, Y., Labib, K., Liang, A., Rouse, J., Rousseau, A., Sapkota, G., Virdee, S. & Walden, H.
1/04/18 → 1/04/24
Project: Research
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Novel Genome Integrity Pathways that Regulate DNA Replication Termination in Metazoa
1/03/18 → 31/08/23
Project: Research
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Functional Dissection of the Eukaryotic Replisome (Senior Investigator Award)
1/04/14 → 29/02/20
Project: Research
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Multiple UBX proteins reduce the ubiquitin threshold of the mammalian p97-UFD1-NPL4 unfoldase
Fujisawa, R., Polo Rivera, C. & Labib, K., 15 Aug 2022, In: eLife. 11, 27 p., e76763.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)7 Downloads (Pure) -
Spt5 histone binding activity preserves chromatin during transcription by RNA polymerase II
Evrin, C., Serra-Cardona, A., Duan, S., Mukherjee, P. P., Zhang, Z. & Labib, K. P. M., 1 Mar 2022, In: EMBO Journal. 41, 5, p. 1-14 14 p., e109783.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)75 Downloads (Pure) -
A Conserved Mechanism for Regulating Replisome Disassembly in Eukaryotes
Jenkyn-Bedford, M., Jones, M. L., Baris, Y., Labib, K. P. M., Cannone, G., Yeeles, J. T. P. & Deegan, T. D., 23 Dec 2021, In: Nature. 600, p. 743-747 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)28 Downloads (Pure) -
CUL2LRR1, TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle
Villa, F., Fujisawa, R., Ainsworth, J., Nishimura, K., Lie-A-Ling, M., Lacaud, G. & Labib, K., 3 Mar 2021, In: EMBO Reports. 22, 3, 13 p., e52164.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)138 Downloads (Pure) -
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease
Canal, B., McClure, A. W., Curran, J. F., Wu, M., Ulferts, R., Weissmann, F., Zeng, J., Bertolin, A. P., Milligan, J. C., Basu, S., Drury, L. S., Deegan, T. D., Fujisawa, R., Roberts, E. L., Basier, C., Labib, K., Beale, R., Howell, M. & Diffley, J. F. X., 2 Jul 2021, In: Biochemical Journal. 478, 13, p. 2445-2464 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)70 Downloads (Pure)
Prizes
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Fellowship of the Royal Society of Edinburgh
Labib, Karim (Recipient), 2016
Prize: Election to learned society
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Long-term Doctoral Fellowship (1993-1994)
Labib, Karim (Recipient), 1993
Prize: Fellowship awarded competitively
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Senior Cancer Research Fellowship, 2001-2007
Labib, Karim (Recipient), 2001
Prize: Fellowship awarded competitively
Activities
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Cafe Science Dundee: A Brief History of Life
Karim Labib (Speaker), Jonathan Urch (Organiser) & Benjamin Vincent (Chair)
5 Oct 2017Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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2014 Ramon Areces Foundation Symposium on ‘Cell Proliferation and Genome Integrity’, University of Santander, Spain
Karim Labib (Organiser)
2014Activity: Participating in or organising an event types › Participation in conference
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Discovery Days 2014
Jonathan Urch (Organiser), Pete Downes (Chair), Karl Leydecker (Presenter), Graeme Hutton (Presenter), Charlotte Proby (Presenter), Amin Abdolvand (Presenter), Doreen Cantrell (Chair), John Rowan (Presenter), Bruce Burton (Presenter), David Horn (Presenter), John Connell (Chair), Ewan Pearson (Presenter), Ruth O'Riordan (Presenter), Graeme Morton (Presenter), Anna Campbell (Presenter), John Baldacchino (Presenter), Karim Labib (Presenter), Stephen Decent (Chair), Fraser Smith (Presenter), Ioannis Anastasopoulos (Presenter), Deborah Peel (Presenter), Christopher Whatley (Chair), Ioan Fazey (Presenter), Graham Chadwick (Presenter), James Livesey (Presenter), Mark Robson (Presenter), Rory McCrimmon (Presenter) & Christopher Connolly (Presenter)
9 Jan 2014 → 10 Jan 2014Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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2014 FASEB Yeast Chromosome Structure, Replication and Segregation meeting, Stemboat Springs, CO, USA
Karim Labib (Invited speaker)
2014Activity: Participating in or organising an event types › Participation in conference
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2013 Conference to celebrate 50th anniversary of the replicon theory, Pasteur Institute, Paris, France
Karim Labib (Invited speaker)
2013Activity: Participating in or organising an event types › Participation in conference