Matthews, Keith

Professor

  • 8688 Citations
  • 45 h-Index
1989 …2019

Research output per year

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Research Output

2019

A Randomized Trial Directly Comparing Ventral Capsule and Anteromedial Subthalamic Nucleus Stimulation in Obsessive-Compulsive Disorder: Clinical and Imaging Evidence for Dissociable Effects

Tyagi, H., Apergis-Schoute, A. M., Akram, H., Foltynie, T., Limousin, P., Drummond, L. M., Fineberg, N. A., Matthews, K., Jahanshahi, M., Robbins, T. W., Sahakian, B. J., Zrinzo, L., Hariz, M. & Joyce, E. M., 1 May 2019, In : Biological Psychiatry. 85, 9, p. 726-734 9 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
72 Downloads (Pure)
1 Citation (Scopus)

Deep brain stimulation: current challenges and future directions

Lozano, A. M., Lipsman, N., Bergman, H., Brown, P., Chabardes, S., Chang, J. W., Matthews, K., McIntyre, C. C., Schlaepfer, T. E., Schulder, M., Temel, Y., Volkmann, J. & Krauss, J. K., Mar 2019, In : Nature Reviews Neurology. 15, 3, p. 148-160 13 p.

Research output: Contribution to journalReview article

32 Citations (Scopus)
Open Access
File
1 Citation (Scopus)
94 Downloads (Pure)

Profiles of visuospatial memory dysfunction in opioid exposed and dependent populations

Baldacchino, A., Tolomeo, S., Balfour, D. & Matthews, K., May 2019, In : Psychological Medicine. 49, 7, p. 1174-1184 11 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
98 Downloads (Pure)
2018

Analysis of shared heritability in common disorders of the brain

Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y., Berr, C. & 30 others, Letenneur, L., Hannequin, D., Amouyel, P., Boland, A., Deleuze, J-F., Duron, E., Vardarajan, B. N., Reitz, C., Goate, A. M., Huentelman, M. J., Kamboh, M. I., Larson, E. B., Rogaeva, E., St George-Hyslop, P., Hakonarson, H., Kukull, W. A., Farrer, L. A., Barnes, L. L., Beach, T. G., Demirci, F. Y., Head, E., Hulette, C. M., Jicha, G. A., Kauwe, J. S. K., Kaye, J. A., Smith, A. G., Matthews, K., McIntosh, A., Robertson, M. M. & Cohen, D., 22 Jun 2018, In : Science. 360, 6395, p. 1-15 15 p., eaap8757.

Research output: Contribution to journalArticle

Open Access
File
323 Citations (Scopus)
822 Downloads (Pure)
Open Access
File
80 Downloads (Pure)

Compulsivity in opioid dependence

Tolomeo, S., Matthews, K., Steele, J. D. & Baldacchino, A., 2 Feb 2018, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 81, p. 333-339 7 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
198 Downloads (Pure)
Open Access
File
22 Citations (Scopus)
131 Downloads (Pure)
Open Access
File
3 Citations (Scopus)
68 Downloads (Pure)
2017

Neuropsychological functioning and chronic methadone use: a systematic review and meta-analysis

Baldacchino, A., Armanyous, M., Balfour, D. J. K., Humphris, G. & Matthews, K., 1 Feb 2017, In : Neuroscience and Biobehavioral Reviews. 73, p. 23-38 16 p.

Research output: Contribution to journalReview article

Open Access
File
13 Citations (Scopus)
200 Downloads (Pure)

Subcallosal cingulate deep brain stimulation for treatment-resistant depression: a multi-site, randomized, sham-controlled trial

Holtzheimer, P., Husain, M. M., Lisanby, S. H., Taylor, S. F., Whitworth, L. A., McClintock, S., Slavin, K. V., Berman, J., McKhann, G. M., Patil, P. G., Rittberg, B. R., Abosch, A., Pandurangi, A. K., Holloway, K. L., Lam, R. W., Connolly, C., Neimat, J. S., Henderson, J. M., DeBattista, C., Rothschild, A. J. & 10 others, Pilitsis, J. G., Espinoza, R. T., Petrides, G., Mogilner, A. Y., Matthews, K., Peichel, D., Grosse, R., Hamani, C., Lozano, A. M. & Mayberg, H. S., Nov 2017, In : Lancet Psychiatry. 4, 11, p. 839-849 11 p.

Research output: Contribution to journalArticle

Open Access
File
117 Citations (Scopus)
793 Downloads (Pure)
2016

A causal role for the anterior mid-cingulate cortex in negative affect and cognitive control

Tolomeo, S., Christmas, D., Jentzsch, I., Johnston, B., Sprengelmeyer, R., Matthews, K. & Steele, J. D., 1 Jun 2016, In : Brain. 139, 6, p. 1844-1854 11 p.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
150 Downloads (Pure)

Autobiographical memory specificity in response to verbal and pictorial cues in clinical depression

Ridout, N., Dritschel, B., Matthews, K. & O'Carroll, R., Jun 2016, In : Journal of Behavior Therapy and Experimental Psychiatry. 51, p. 109-115 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Multifaceted impairments in impulsivity and brain structural abnormalities in opioid dependence and abstinence

Tolomeo, S., Gray, S., Matthews, K., Steele, J. D. & Baldacchino, A., Oct 2016, In : Psychological Medicine. 46, 13, p. 2841-2853 13 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
143 Downloads (Pure)
Open Access
File
3 Citations (Scopus)
463 Downloads (Pure)
2015

Abnormal brain responses to social fairness in depression: an fMRI study using the Ultimatum Game

Gradin, V. B., Pérez, A., MacFarlane, J. A., Cavin, I., Waiter, G., Engelmann, J., Dritschel, B., Pomi, A., Matthews, K. & Steele, J. D., Apr 2015, In : Psychological Medicine. 45, 6, p. 1241-1251 11 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
10 Citations (Scopus)

Efficacy of cognitive-behavioral therapy for obsessive-compulsive disorder

McKay, D., Sookman, D., Neziroglu, F., Wilhelm, S., Stein, D. J., Kyrios, M., Matthews, K. & Veale, D., 28 Feb 2015, In : Psychiatry Research. 225, 3, p. 236-246 11 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Epidemiology and heritability of Major Depressive Disorder, stratified by age of onset, sex, and illness course in Generation Scotland: Scottish Family Health Study (GS:SFHS)

Fernandez-Pujals, A. M., Adams, M. J., Thomson, P., McKechanie, A. G., Blackwood, D. H. R., Smith, B. H., Dominiczak, A. F., Morris, A. D., Matthews, K., Campbell, A., Linksted, P., Haley, C. S., Deary, I. J., Porteous, D. J., MacIntyre, D. J. & McIntosh, A. M., 16 Nov 2015, In : PLoS ONE. 10, 11, 18 p., e0142197.

Research output: Contribution to journalArticle

Open Access
File
37 Citations (Scopus)
261 Downloads (Pure)

Failure of hippocampal deactivation during loss events in treatment-resistant depression

Johnston, B. A., Tolomeo, S., Gradin, V., Christmas, D., Matthews, K. & Steele, J. D., Sep 2015, In : Brain. 138, 9, p. 2766-2776 11 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
164 Downloads (Pure)

Impulsivity and opioid drugs: differential effects of heroin, methadone and prescribed analgesic medication

Baldacchino, A., Balfour, D. J. K. & Matthews, K., Apr 2015, In : Psychological Medicine. 45, 6, p. 1167-1179 13 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Obsessive-compulsive disorder (OCD): Practical strategies for pharmacological and somatic treatment in adults

Fineberg, N. A., Reghunandanan, S., Simpson, H. B., Phillips, K. A., Richter, M. A., Matthews, K., Stein, D. J., Sareen, J., Brown, A. & Sookman, D., 30 May 2015, In : Psychiatry Research. 227, 1, p. 114-125 12 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Predicting methylphenidate response in attention deficit hyperactivity disorder: a preliminary study

Johnston, B. A., Coghill, D., Matthews, K. & Steele, J. D., Jan 2015, In : Journal of Psychopharmacology. 29, 1, p. 24-30 7 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Somatic symptom count scores do not identify patients with symptoms unexplained by disease: a prospective cohort study of neurology outpatients

Carson, A. J., Stone, J., Hansen, C. H., Duncan, R., Cavanagh, J., Matthews, K., Murray, G. & Sharpe, M., Mar 2015, In : Journal of Neurology, Neurosurgery and Psychiatry. 86, 3, p. 295-301 7 p.

Research output: Contribution to journalArticle

Structural MRI-based predictions in patients with treatment-refractory depression (TRD)

Johnston, B. A., Steele, J. D., Tolomeo, S., Christmas, D. & Matthews, K., 17 Jul 2015, In : PLoS ONE. 10, 7, 16 p., 0132958.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2014

Abnormal Brain Activity During a Reward and Loss Task in Opiate Dependent Patients Receiving Methadone Maintenance Therapy

Gradin, V. B., Baldacchino, A., Balfour, D., Matthews, K. & Steele, J. D., Mar 2014, In : Neuropsychopharmacology. 39, 4, p. 885-894 10 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
71 Citations (Scopus)

Brainstem abnormalities in attention deficit hyperactivity disorder support high accuracy individual diagnostic classification

Johnston, B. A., Mwangi, B., Matthews, K., Coghill, D., Konrad, K. & Steele, J. D., Oct 2014, In : Human Brain Mapping. 35, 10, p. 5179-5189 11 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Cognitive Behavioural Analysis System of Psychotherapy (CBASP) for chronic depression: clinical characteristics and six month clinical outcomes in an open case series

Swan, J. S., MacVicar, R., Christmas, D., Durham, R., Rauchhaus, P., McCullough Jr, J. P. & Matthews, K., Jan 2014, In : Journal of Affective Disorders. 152-154, p. 268-276 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Consensus on guidelines for stereotactic neurosurgery for psychiatric disorders

Nuttin, B., Wu, H., Mayberg, H., Hariz, M., Gabriëls, L., Galert, T., Merkel, R., Kubu, C., Vilela-Filho, O., Matthews, K., Taira, T., Lozano, A. M., Schechtmann, G., Doshi, P., Broggi, G., Régis, J., Alkhani, A., Sun, B., Eljamel, S., Schulder, M. & 14 others, Kaplitt, M., Eskandar, E., Rezai, A., Krauss, J. K., Hilven, P., Schuurman, R., Ruiz, P., Chang, J. W., Cosyns, P., Lipsman, N., Voges, J., Cosgrove, R., Li, Y. & Schlaepfer, T., 2014, In : Journal of Neurology, Neurosurgery and Psychiatry. 85, 9, p. 1003-1008 6 p.

Research output: Contribution to journalArticle

Open Access
File
80 Citations (Scopus)
133 Downloads (Pure)

Identification of pathways for bipolar disorder: A meta-analysis

Nurnberger, J. I., Koller, D. L., Jung, J., Edenberg, H. J., Foroud, T., Guella, I., Vawter, M. P. & Kelsoe, J. R., 1 Jun 2014, In : JAMA Psychiatry. 71, 6, p. 657-664 8 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

Neurosurgery for obsessive-compulsive disorder, other anxiety disorders and depressive disorders

Christmas, D. M. B., Crombie, I., Eljamel, S., Fineberg, N., Macvicar, B., Matthews, K., Ruck, C. & Stark, C., 25 Feb 2014, In : Cochrane Database of Systematic Reviews. 2014, 2, CD005560.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Or09-1cognitive impulsivity and chronic opioid use

Baldacchino, A. M., Balfour, D. J. & Matthews, K., 12 Sep 2014, In : Alcohol and Alcoholism. 49 Suppl 1, p. i46 1 p.

Research output: Contribution to journalArticle

Putative transcriptomic biomarkers in the inflammatory cytokine pathway differentiate major depressive disorder patients from control subjects and bipolar disorder patients

Powell, T. R., McGuffin, P., D'Souza, U. M., Cohen-Woods, S., Hosang, G. M., Martin, C., Matthews, K., Day, R. K., Farmer, A. E., Tansey, K. E. & Schalkwyk, L. C., 11 Mar 2014, In : PLoS ONE. 9, 3, e91076.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
115 Downloads (Pure)
2013
87 Citations (Scopus)

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Lee, S. H., Ripke, S., Neale, B. M., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Anney, R., Anttila, V., Arking, D. E., Asherson, P. & 31 others, Azevedo, M. H., Backlund, L., Badner, J. A., Bailey, A. J., Banaschewski, T., Barchas, J. D., Barnes, M. R., Barrett, T. B., Bass, N., Battaglia, A., Bauer, M., Bayés, M., Bellivier, F., Bergen, S. E., Berrettini, W., Betancur, C., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H. R., Bloss, C. S., Boehnke, M., Boomsma, D. I., Breen, G., Breuer, R., Bruggeman, R., Cormican, P., Day, R., Matthews, K. & Cross-Disorder Group of the Psychiatric Genomics Consortium, 2013, In : Nature Genetics. 45, p. 984-994 11 p.

Research output: Contribution to journalArticle

1189 Citations (Scopus)

Salience network-midbrain dysconnectivity and blunted reward signals in schizophrenia

Gradin, V. B., Waiter, G., O'Connor, A., Romaniuk, L., Stickle, C., Matthews, K., Hall, J. & Steele, J. D., 28 Feb 2013, In : Psychiatry Research: Neuroimaging. 211, 2, p. 104-111 8 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

The clinical utility of different quantitative methods for measuring treatment resistance in major depression

Hazari, H., Christmas, D. & Matthews, K., 5 Sep 2013, In : Journal of Affective Disorders. 150, 2, p. 231-236 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Vagal Nerve Stimulation in Treatment of Refractory Major Depression

Matthews, C., Tolomeo, S. & Matthews, K., 19 Jul 2013, Neurostimulation: Principles and Practice. Eljamel, S. & Slavin, K. V. (eds.). Wiley, p. 131-141 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Vagus nerve stimulation for chronic major depressive disorder: 12-month outcomes in highly treatment-refractory patients

Christmas, D., Steele, J. D., Tolomeo, S., Eljamel, M. S. & Matthews, K., 25 Sep 2013, In : Journal of Affective Disorders. 150, 3, p. 1221-1225

Research output: Contribution to journalArticle

33 Citations (Scopus)
2012

Abnormal neural responses to social exclusion in schizophrenia

Gradin, V. B., Waiter, G., Kumar, P., Stickle, C., Milders, M., Matthews, K., Reid, I., Hall, J. & Steele, J. D., 16 Aug 2012, In : PLoS ONE. 7, 8, p. - 7 p., e42608.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Multi-centre diagnostic classification of individual structural neuroimaging scans from patients with major depressive disorder

Mwangi, B., Ebmeier, K. P., Matthews, K. & Steele, J. D., May 2012, In : Brain. 135, 5, p. 1508-1521 14 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)

Neural responses to rewards and punishments in patients with opiate dependence on methadone treatment: fNEMO study

Gradin, V., Gray, S., MacFarlane, J., Waiter, G., Balfour, D., Matthews, K., Baldacchino, A. & Steele, D., Oct 2012, In : European Neuropsychopharmacology. 22, Suppl 2, p. S402-S403 2 p., P.6.c.008.

Research output: Contribution to journalMeeting abstract

Neuropsychological consequences of chronic opioid use: a quantitative review and meta-analysis

Baldacchino, A., Balfour, D. J. K., Passetti, F., Humphris, G. & Matthews, K., 2012, In : Neuroscience and Biobehavioral Reviews. 36, 9, p. 2056-2068 13 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)
42 Citations (Scopus)

Predictive classification of individual magnetic resonance imaging scans from children and adolescents

Johnston, B. A., Mwangi, B., Matthews, K., Coghill, D. & Steele, J. D., Dec 2012, In : European Child & Adolescent Psychiatry. 22, 12, p. 733-744 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Which neurological diseases are most likely to be associated with "symptoms unexplained by organic disease"

Stone, J., Carson, A., Duncan, R., Roberts, R., Coleman, R., Warlow, C., Murray, G., Pelosi, A., Cavanagh, J., Matthews, K., Goldbeck, R. & Sharpe, M., 2012, In : Journal of Neurology. 259, 1, p. 33-38 6 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2011

Abnormal medial prefrontal cortex responses to social exclusion in schizophrenia: an FMRI study

Gradin, V., Waiter, G., Kumar, P., Ahearn, T., Stickle, C., Milders, M., Matthews, K., Reid, I., Hall, J. & Steele, J. D., Sep 2011, In : European Neuropsychopharmacology. 21, p. S305-S305 1 p., P.1.e.004.

Research output: Contribution to journalBook/Film/Article review