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1989 …2019
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Research Output 1989 2019

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Article
2019
7 Citations (Scopus)
23 Downloads (Pure)

A Randomized Trial Directly Comparing Ventral Capsule and Anteromedial Subthalamic Nucleus Stimulation in Obsessive-Compulsive Disorder: Clinical and Imaging Evidence for Dissociable Effects

Tyagi, H., Apergis-Schoute, A. M., Akram, H., Foltynie, T., Limousin, P., Drummond, L. M., Fineberg, N. A., Matthews, K., Jahanshahi, M., Robbins, T. W., Sahakian, B. J., Zrinzo, L., Hariz, M. & Joyce, E. M., 1 May 2019, In : Biological Psychiatry. 85, 9, p. 726-734 9 p.

Research output: Contribution to journalArticle

Open Access
File
Anterior Thalamic Nuclei
Subthalamic Nucleus
Deep Brain Stimulation
Obsessive-Compulsive Disorder
Capsules
Chronic Pain
Opioid Analgesics
Psychiatry
Morbidity
Scotland
1 Citation (Scopus)
Hyperalgesia
Opioid Analgesics
Meta-Analysis
Population
Pain
2018
131 Citations (Scopus)
709 Downloads (Pure)

Analysis of shared heritability in common disorders of the brain

Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y., Berr, C. & 30 others, Letenneur, L., Hannequin, D., Amouyel, P., Boland, A., Deleuze, J-F., Duron, E., Vardarajan, B. N., Reitz, C., Goate, A. M., Huentelman, M. J., Kamboh, M. I., Larson, E. B., Rogaeva, E., St George-Hyslop, P., Hakonarson, H., Kukull, W. A., Farrer, L. A., Barnes, L. L., Beach, T. G., Demirci, F. Y., Head, E., Hulette, C. M., Jicha, G. A., Kauwe, J. S. K., Kaye, J. A., Smith, A. G., Matthews, K., McIntosh, A., Robertson, M. M. & Cohen, D., 22 Jun 2018, In : Science. 360, 6395, p. 1-15 15 p., eaap8757.

Research output: Contribution to journalArticle

Open Access
File
Brain Diseases
Psychiatry
Phenotype
Genetic Heterogeneity
Genome-Wide Association Study
4 Downloads (Pure)

Co-morbid psychiatric symptoms and clinical outcomes for treatment – seeking opioiddependent patients prescribed methadone opioid substitution therapy (OST): a 7 year prospective cohort study

Kidd, B., Matthews, K. & Higgins, C., 10 Dec 2018, In : Mental Health and Addiction Research. 3, 4, 7 p.

Research output: Contribution to journalArticle

Open Access
File
Opiate Substitution Treatment
Methadone
Psychiatry
Cohort Studies
Prospective Studies
4 Citations (Scopus)
85 Downloads (Pure)

Compulsivity in opioid dependence

Tolomeo, S., Matthews, K., Steele, J. D. & Baldacchino, A., 2 Feb 2018, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 81, p. 333-339 7 p.

Research output: Contribution to journalArticle

Open Access
File
Opioid Analgesics
Impulsive Behavior
Heroin
Magnetic Resonance Imaging
Septal Nuclei
24 Downloads (Pure)

Profiles of visuospatial memory dysfunction in opioid exposed and dependent populations

Baldacchino, A., Tolomeo, S., Balfour, D. & Matthews, K., 20 Nov 2018, In : Psychological Medicine. 11 p.

Research output: Contribution to journalArticle

Open Access
File
Heroin
Methadone
Opioid Analgesics
Population
Intelligence
Cannabinoids
Methadone
Benzodiazepines
Chronic Pain
Opioid Analgesics
2017
71 Citations (Scopus)
171 Downloads (Pure)

Subcallosal cingulate deep brain stimulation for treatment-resistant depression: a multi-site, randomized, sham-controlled trial

Holtzheimer, P., Husain, M. M., Lisanby, S. H., Taylor, S. F., Whitworth, L. A., McClintock, S., Slavin, K. V., Berman, J., McKhann, G. M., Patil, P. G., Rittberg, B. R., Abosch, A., Pandurangi, A. K., Holloway, K. L., Lam, R. W., Connolly, C., Neimat, J. S., Henderson, J. M., DeBattista, C., Rothschild, A. J. & 10 others, Pilitsis, J. G., Espinoza, R. T., Petrides, G., Mogilner, A. Y., Matthews, K., Peichel, D., Grosse, R., Hamani, C., Lozano, A. M. & Mayberg, H. S., Nov 2017, In : Lancet Psychiatry. 4, 11, p. 839-849 11 p.

Research output: Contribution to journalArticle

Open Access
File
Treatment-Resistant Depressive Disorder
Deep Brain Stimulation
Randomized Controlled Trials
Medical Futility
Depression
2016
13 Citations (Scopus)
84 Downloads (Pure)

A causal role for the anterior mid-cingulate cortex in negative affect and cognitive control

Tolomeo, S., Christmas, D., Jentzsch, I., Johnston, B., Sprengelmeyer, R., Matthews, K. & Steele, J. D., 1 Jun 2016, In : Brain. 139, 6, p. 1844-1854 11 p.

Research output: Contribution to journalArticle

Open Access
File
Gyrus Cinguli
Facial Expression
Treatment-Resistant Depressive Disorder
Pain
Stroop Test
6 Citations (Scopus)

Autobiographical memory specificity in response to verbal and pictorial cues in clinical depression

Ridout, N., Dritschel, B., Matthews, K. & O'Carroll, R., Jun 2016, In : Journal of Behavior Therapy and Experimental Psychiatry. 51, p. 109-115 7 p.

Research output: Contribution to journalArticle

Episodic Memory
Cues
Depression
Memory Disorders
Post-Traumatic Stress Disorders
10 Citations (Scopus)
62 Downloads (Pure)

Multifaceted impairments in impulsivity and brain structural abnormalities in opioid dependence and abstinence

Tolomeo, S., Gray, S., Matthews, K., Steele, J. D. & Baldacchino, A., 2016, In : Psychological Medicine. 46, 13, p. 2841-2853 13 p.

Research output: Contribution to journalArticle

Open Access
File
Impulsive Behavior
Methadone
Opioid Analgesics
Brain
Gambling
3 Citations (Scopus)
237 Downloads (Pure)
Open Access
File
Treatment-Resistant Depressive Disorder
Vagus Nerve Stimulation
Severity of Illness Index
Therapeutics
2015
21 Citations (Scopus)

Abnormal brain responses to social fairness in depression: an fMRI study using the Ultimatum Game

Gradin, V. B., Pérez, A., MacFarlane, J. A., Cavin, I., Waiter, G., Engelmann, J., Dritschel, B., Pomi, A., Matthews, K. & Steele, J. D., Apr 2015, In : Psychological Medicine. 45, 6, p. 1241-1251 11 p.

Research output: Contribution to journalArticle

Nucleus Accumbens
Behavioral Economics
Magnetic Resonance Imaging
Depression
Automatic Data Processing
8 Citations (Scopus)
Guideline Adherence
Suicide
Guidelines
30 Citations (Scopus)

Efficacy of cognitive-behavioral therapy for obsessive-compulsive disorder

McKay, D., Sookman, D., Neziroglu, F., Wilhelm, S., Stein, D. J., Kyrios, M., Matthews, K. & Veale, D., 28 Feb 2015, In : Psychiatry Research. 225, 3, p. 236-246 11 p.

Research output: Contribution to journalArticle

Obsessive-Compulsive Disorder
Cognitive Therapy
Research
General Practice
Meta-Analysis
28 Citations (Scopus)
196 Downloads (Pure)

Epidemiology and heritability of Major Depressive Disorder, stratified by age of onset, sex, and illness course in Generation Scotland: Scottish Family Health Study (GS:SFHS)

Fernandez-Pujals, A. M., Adams, M. J., Thomson, P., McKechanie, A. G., Blackwood, D. H. R., Smith, B. H., Dominiczak, A. F., Morris, A. D., Matthews, K., Campbell, A., Linksted, P., Haley, C. S., Deary, I. J., Porteous, D. J., MacIntyre, D. J. & McIntosh, A. M., 16 Nov 2015, In : PLoS ONE. 10, 11, 18 p., e0142197.

Research output: Contribution to journalArticle

Open Access
File
Epidemiology
Family Health
Major Depressive Disorder
Scotland
Age of Onset
13 Citations (Scopus)
94 Downloads (Pure)

Failure of hippocampal deactivation during loss events in treatment-resistant depression

Johnston, B. A., Tolomeo, S., Gradin, V., Christmas, D., Matthews, K. & Steele, J. D., Sep 2015, In : Brain. 138, 9, p. 2766-2776 11 p.

Research output: Contribution to journalArticle

Open Access
File
Treatment-Resistant Depressive Disorder
Major Depressive Disorder
Raphe Nuclei
Hippocampus
Periaqueductal Gray
16 Citations (Scopus)

Impulsivity and opioid drugs: differential effects of heroin, methadone and prescribed analgesic medication

Baldacchino, A., Balfour, D. J. K. & Matthews, K., Apr 2015, In : Psychological Medicine. 45, 6, p. 1167-1179 13 p.

Research output: Contribution to journalArticle

Impulsive Behavior
Methadone
Heroin
Opioid Analgesics
Analgesics
42 Citations (Scopus)

Obsessive-compulsive disorder (OCD): Practical strategies for pharmacological and somatic treatment in adults

Fineberg, N. A., Reghunandanan, S., Simpson, H. B., Phillips, K. A., Richter, M. A., Matthews, K., Stein, D. J., Sareen, J., Brown, A. & Sookman, D., 30 May 2015, In : Psychiatry Research. 227, 1, p. 114-125 12 p.

Research output: Contribution to journalArticle

Obsessive-Compulsive Disorder
Pharmacology
Serotonin Uptake Inhibitors
Therapeutics
Clomipramine
21 Citations (Scopus)

Predicting methylphenidate response in attention deficit hyperactivity disorder: a preliminary study

Johnston, B. A., Coghill, D., Matthews, K. & Steele, J. D., Jan 2015, In : Journal of Psychopharmacology. 29, 1, p. 24-30 7 p.

Research output: Contribution to journalArticle

Methylphenidate
Attention Deficit Disorder with Hyperactivity
Conduct Disorder
Intelligence
Multivariate Analysis

Somatic symptom count scores do not identify patients with symptoms unexplained by disease: a prospective cohort study of neurology outpatients

Carson, A. J., Stone, J., Hansen, C. H., Duncan, R., Cavanagh, J., Matthews, K., Murray, G. & Sharpe, M., Mar 2015, In : Journal of Neurology, Neurosurgery and Psychiatry. 86, 3, p. 295-301 7 p.

Research output: Contribution to journalArticle

Neurology
Cohort Studies
Outpatients
Prospective Studies
Scotland
15 Citations (Scopus)

Structural MRI-based predictions in patients with treatment-refractory depression (TRD)

Johnston, B. A., Steele, J. D., Tolomeo, S., Christmas, D. & Matthews, K., 17 Jul 2015, In : PLoS ONE. 10, 7, 16 p., 0132958.

Research output: Contribution to journalArticle

2014
17 Citations (Scopus)

Abnormal Brain Activity During a Reward and Loss Task in Opiate Dependent Patients Receiving Methadone Maintenance Therapy

Gradin, V. B., Baldacchino, A., Balfour, D., Matthews, K. & Steele, J. D., Mar 2014, In : Neuropsychopharmacology. 39, 4, p. 885-894 10 p.

Research output: Contribution to journalArticle

Opiate Alkaloids
Methadone
Reward
Brain
Therapeutics
65 Citations (Scopus)
Attention Deficit Disorder with Hyperactivity
Biomarkers
Neuropsychological Tests
41 Citations (Scopus)

Brainstem abnormalities in attention deficit hyperactivity disorder support high accuracy individual diagnostic classification

Johnston, B. A., Mwangi, B., Matthews, K., Coghill, D., Konrad, K. & Steele, J. D., Oct 2014, In : Human Brain Mapping. 35, 10, p. 5179-5189 11 p.

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Brain Stem
Psychiatry
Brain
Biomarkers
12 Citations (Scopus)

Cognitive Behavioural Analysis System of Psychotherapy (CBASP) for chronic depression: clinical characteristics and six month clinical outcomes in an open case series

Swan, J. S., MacVicar, R., Christmas, D., Durham, R., Rauchhaus, P., McCullough Jr, J. P. & Matthews, K., Jan 2014, In : Journal of Affective Disorders. 152-154, p. 268-276 9 p.

Research output: Contribution to journalArticle

National Health Programs
Psychotherapy
Depression
70 Citations (Scopus)
60 Downloads (Pure)

Consensus on guidelines for stereotactic neurosurgery for psychiatric disorders

Nuttin, B., Wu, H., Mayberg, H., Hariz, M., Gabriëls, L., Galert, T., Merkel, R., Kubu, C., Vilela-Filho, O., Matthews, K., Taira, T., Lozano, A. M., Schechtmann, G., Doshi, P., Broggi, G., Régis, J., Alkhani, A., Sun, B., Eljamel, S., Schulder, M. & 14 others, Kaplitt, M., Eskandar, E., Rezai, A., Krauss, J. K., Hilven, P., Schuurman, R., Ruiz, P., Chang, J. W., Cosyns, P., Lipsman, N., Voges, J., Cosgrove, R., Li, Y. & Schlaepfer, T., 2014, In : Journal of Neurology, Neurosurgery and Psychiatry. 85, 9, p. 1003-1008 6 p.

Research output: Contribution to journalArticle

Open Access
File
Neurosurgery
Psychiatry
Consensus
Guidelines
Brain Diseases
103 Citations (Scopus)

Identification of pathways for bipolar disorder: A meta-analysis

Nurnberger, J. I., Koller, D. L., Jung, J., Edenberg, H. J., Foroud, T., Guella, I., Vawter, M. P. & Kelsoe, J. R., 1 Jun 2014, In : JAMA Psychiatry. 71, 6, p. 657-664 8 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Meta-Analysis
Genes
Genome-Wide Association Study
Psychiatry
3 Citations (Scopus)

Neurosurgery for obsessive-compulsive disorder, other anxiety disorders and depressive disorders

Christmas, D. M. B., Crombie, I., Eljamel, S., Fineberg, N., Macvicar, B., Matthews, K., Ruck, C. & Stark, C., 25 Feb 2014, In : Cochrane Database of Systematic Reviews. 2014, 2, CD005560.

Research output: Contribution to journalArticle

Neurosurgical Procedures
Obsessive-Compulsive Disorder
Neurosurgery
Depressive Disorder
Anxiety Disorders

Or09-1cognitive impulsivity and chronic opioid use

Baldacchino, A. M., Balfour, D. J. & Matthews, K., 12 Sep 2014, In : Alcohol and Alcoholism. 49 Suppl 1, p. i46 1 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
51 Downloads (Pure)

Putative transcriptomic biomarkers in the inflammatory cytokine pathway differentiate major depressive disorder patients from control subjects and bipolar disorder patients

Powell, T. R., McGuffin, P., D'Souza, U. M., Cohen-Woods, S., Hosang, G. M., Martin, C., Matthews, K., Day, R. K., Farmer, A. E., Tansey, K. E. & Schalkwyk, L. C., 11 Mar 2014, In : PLoS ONE. 9, 3, e91076.

Research output: Contribution to journalArticle

Open Access
File
Major Depressive Disorder
Biomarkers
transcriptomics
Bipolar Disorder
biomarkers
12 Citations (Scopus)

The 'squeezed middle': Identifying and addressing conflicting demands on intermediate quality farmland in Scotland

Slee, B., Brown, I., Donnelly, D., Gordon, I. J., Matthews, K. & Towers, W., Nov 2014, In : Land Use Policy. 41, p. 206-216 11 p.

Research output: Contribution to journalArticle

Scotland
agricultural land
land use
ecosystem service
ecosystem services
2013
75 Citations (Scopus)
Attention Deficit Disorder with Hyperactivity
Decision Making
Short-Term Memory
Inhibition (Psychology)
Statistical Factor Analysis
1051 Citations (Scopus)

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Lee, S. H., Ripke, S., Neale, B. M., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Anney, R., Anttila, V., Arking, D. E., Asherson, P. & 31 others, Azevedo, M. H., Backlund, L., Badner, J. A., Bailey, A. J., Banaschewski, T., Barchas, J. D., Barnes, M. R., Barrett, T. B., Bass, N., Battaglia, A., Bauer, M., Bayés, M., Bellivier, F., Bergen, S. E., Berrettini, W., Betancur, C., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H. R., Bloss, C. S., Boehnke, M., Boomsma, D. I., Breen, G., Breuer, R., Bruggeman, R., Cormican, P., Day, R., Matthews, K. & Cross-Disorder Group of the Psychiatric Genomics Consortium, 2013, In : Nature Genetics. 45, p. 984-994 11 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Single Nucleotide Polymorphism
Psychiatry
Schizophrenia
Bipolar Disorder
41 Citations (Scopus)

Salience network-midbrain dysconnectivity and blunted reward signals in schizophrenia

Gradin, V. B., Waiter, G., O'Connor, A., Romaniuk, L., Stickle, C., Matthews, K., Hall, J. & Steele, J. D., 28 Feb 2013, In : Psychiatry Research: Neuroimaging. 211, 2, p. 104-111 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The clinical utility of different quantitative methods for measuring treatment resistance in major depression

Hazari, H., Christmas, D. & Matthews, K., 5 Sep 2013, In : Journal of Affective Disorders. 150, 2, p. 231-236 6 p.

Research output: Contribution to journalArticle

Aptitude
Depression
Mood Disorders
Therapeutics
Referral and Consultation
28 Citations (Scopus)

Vagus nerve stimulation for chronic major depressive disorder: 12-month outcomes in highly treatment-refractory patients

Christmas, D., Steele, J. D., Tolomeo, S., Eljamel, M. S. & Matthews, K., 25 Sep 2013, In : Journal of Affective Disorders. 150, 3, p. 1221-1225

Research output: Contribution to journalArticle

Vagus Nerve Stimulation
Major Depressive Disorder
Treatment-Resistant Depressive Disorder
Neurosurgery
Therapeutics
2012
17 Citations (Scopus)

Abnormal neural responses to social exclusion in schizophrenia

Gradin, V. B., Waiter, G., Kumar, P., Stickle, C., Milders, M., Matthews, K., Reid, I., Hall, J. & Steele, J. D., 16 Aug 2012, In : PLoS ONE. 7, 8, p. - 7 p., e42608.

Research output: Contribution to journalArticle

99 Citations (Scopus)

Multi-centre diagnostic classification of individual structural neuroimaging scans from patients with major depressive disorder

Mwangi, B., Ebmeier, K. P., Matthews, K. & Steele, J. D., May 2012, In : Brain. 135, 5, p. 1508-1521 14 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)

Neuropsychological consequences of chronic opioid use: a quantitative review and meta-analysis

Baldacchino, A., Balfour, D. J. K., Passetti, F., Humphris, G. & Matthews, K., 2012, In : Neuroscience and Biobehavioral Reviews. 36, 9, p. 2056-2068 13 p.

Research output: Contribution to journalArticle

Opioid Analgesics
Meta-Analysis
Benchmarking
Neuropsychology
Impulsive Behavior
39 Citations (Scopus)
20 Citations (Scopus)

Predictive classification of individual magnetic resonance imaging scans from children and adolescents

Johnston, B. A., Mwangi, B., Matthews, K., Coghill, D. & Steele, J. D., Dec 2012, In : European Child & Adolescent Psychiatry. 22, 12, p. 733-744 12 p.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Adolescent Psychiatry
Child Psychiatry
Neuroimaging
Psychiatry
34 Citations (Scopus)

Which neurological diseases are most likely to be associated with "symptoms unexplained by organic disease"

Stone, J., Carson, A., Duncan, R., Roberts, R., Coleman, R., Warlow, C., Murray, G., Pelosi, A., Cavanagh, J., Matthews, K., Goldbeck, R. & Sharpe, M., 2012, In : Journal of Neurology. 259, 1, p. 33-38 6 p.

Research output: Contribution to journalArticle

2011
34 Citations (Scopus)

Admixture analysis of age at onset in bipolar disorder

Tozzi, F., Manchia, M., Galwey, N. W., Severino, G., Del Zompo, M., Day, R., Matthews, K., Strauss, J., Kennedy, J. L., McGuffin, P., Vincent, J. B., Farmer, A. & Muglia, P., 30 Jan 2011, In : Psychiatry Research. 185, 1-2, p. 27-32 6 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Attention-deficit/hyperactivity disorder and Williams syndrome: shared behavioral and neuropsychological profiles

Rhodes, S. M., Riby, D. M., Matthews, K. & Coghill, D. R., 2011, In : Journal of Clinical and Experimental Neuropsychology. 33, 1, p. 147-156 10 p.

Research output: Contribution to journalArticle

82 Citations (Scopus)

Disability, distress and unemployment in neurology outpatients with symptoms 'unexplained by organic disease'

Carson, A., Stone, J., Hibberd, C., Murray, G., Duncan, R., Coleman, R., Warlow, C., Roberts, R., Pelosi, A., Cavanagh, J., Matthews, K., Goldbeck, R., Hansen, C. & Sharpe, M., Jul 2011, In : Journal of Neurology, Neurosurgery and Psychiatry. 82, 7, p. 810-813 4 p.

Research output: Contribution to journalArticle

791 Citations (Scopus)

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

Sklar, P., Ripke, S., Scott, L. J., Andreassen, O. A., Cichon, S., Craddock, N., Edenberg, H. J., Nurnberger, J. I., Rietschel, M., Blackwood, D., Corvin, A., Flickinger, M., Guan, W., Mattingsdal, M., McQuillin, A., Kwan, P., Wienker, T. F., Daly, M., Dudbridge, F., Holmans, P. A. & 30 others, Lin, D., Burmeister, M., Greenwood, T. A., Hamshere, M. L., Muglia, P., Smith, E. N., Zandi, P. P., Nievergelt, C. M., McKinney, R., Shilling, P. D., Schork, N. J., Bloss, C. S., Foroud, T., Koller, D. L., Gershon, E. S., Liu, C., Badner, J. A., Scheftner, W. A., Lawson, W. B., Nwulia, E. A., Hipolito, M., Coryell, W., Rice, J., Byerley, W., McMahon, F. J., Schulze, T. G., Matthews, K., Moran, J., McIntosh, A. & Psychiat GWAS Consortium Bipolar D, Oct 2011, In : Nature Genetics. 43, 10, p. 977-983 7 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Long term outcome of thermal anterior capsulotomy for chronic, treatment refractory depression

Christmas, D., Eljamel, M. S., Butler, S., Hazari, H., MacVicar, R., Steele, J. D., Livingstone, A. & Matthews, K., Jun 2011, In : Journal of Neurology, Neurosurgery and Psychiatry. 82, 6, p. 594-600 7 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)

The insular cortex and the neuroanatomy of major depression

Sprengelmeyer, R., Steele, J. D., Mwangi, B., Kumar, P., Christmas, D., Milders, M. & Matthews, K., Sep 2011, In : Journal of Affective Disorders. 133, 1-2, p. 120-127 8 p.

Research output: Contribution to journalArticle