Fernandes, Kenneth

Mr

  • 976 Citations
  • 11 h-Index
20022019
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Fingerprint Dive into the research topics where Kenneth Fernandes is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Protein Isoforms Medicine & Life Sciences
p53 Genes Medicine & Life Sciences
Squamous Cell Carcinoma Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Skin Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Cell Line Medicine & Life Sciences
Spliceosomes Medicine & Life Sciences

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Research Output 2002 2019

  • 976 Citations
  • 11 h-Index
  • 13 Article
  • 2 Chapter (peer-reviewed)
  • 1 Meeting abstract
  • 1 Book/Film/Article review
10 Downloads (Pure)

The Identification of Potential Therapeutic Targets for Cutaneous Squamous Cell Carcinoma

McHugh, A., Fernandes, K., Chinner, N., Ibrahim, A. F. M., Garg, A. K., Boag, G., Hepburn, L. A., Proby, C. M., Leigh, I. M. & Saville, M. K., 6 Nov 2019, In : Journal of Investigative Dermatology. 37 p.

Research output: Contribution to journalArticle

Open Access
File
Squamous Cell Carcinoma
Skin
Anaphase-Promoting Complex-Cyclosome
Therapeutics
Ubiquitin
5 Citations (Scopus)
83 Downloads (Pure)

Preclinical comparison of proteasome and ubiquitin E1 enzyme inhibitors in cutaneous squamous cell carcinoma: the identification of mechanisms of differential sensitivity

McHugh, A., Fernandes, K., South, A., Mellerio, J. E., Salas-Alanis, J. C., Proby, C., Leigh, I. & Saville, M., 17 Apr 2018, In : Oncotarget. 9, p. 20265-20281 17 p.

Research output: Contribution to journalArticle

Open Access
File
Enzyme Inhibitors
Proteasome Endopeptidase Complex
Ubiquitin
Proteasome Inhibitors
Squamous Cell Carcinoma
6 Citations (Scopus)
67 Downloads (Pure)

Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity

Hepburn, L., McHugh, A., Fernandes, K., Boag, G., Proby, C., Leigh, I. & Saville, M., 1 May 2018, In : Oncotarget. 9, 33, p. 23029-23046 18 p.

Research output: Contribution to journalArticle

Open Access
File
Spliceosomes
Cell- and Tissue-Based Therapy
Squamous Cell Carcinoma
Skin
Neoplasms
13 Citations (Scopus)
104 Downloads (Pure)

TP53 drives invasion through expression of its ∆133p53β variant

Gadea, G., Arsic, N., Fernandes, K., Diot, A., Joruiz, S. M., Abdallah, S., Meuray, V., Vinot, S., Anguille, C., Remenyi, J., Khoury, M. P., Quinlan, P. R., Purdie, C. A., Jordan, L. B., Fuller-Pace, F. V., de Toledo, M., Cren, M., Thompson, A. M., Bourdon, J-C. & Roux, P., 15 Sep 2016, In : eLife. 5, p. 1-26 26 p., e14734.

Research output: Contribution to journalArticle

Open Access
File
Cells
Neoplasms
Protein Isoforms
Genes
Mutation
40 Citations (Scopus)

Modulation of p53β and p53γ expression by regulating the alternative splicing of TP53 gene modifies cellular response

Marcel, V., Fernandes, K., Terrier, O., Lane, D. P. & Bourdon, J-C., Sep 2014, In : Cell Death & Differentiation. 21, p. 1377-1387 11 p.

Research output: Contribution to journalArticle

p53 Genes
Alternative Splicing
Exons
RNA Precursors
MCF-7 Cells