Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Dive into the research topics where Kenneth MacLeod is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Novel insights into diabetic heart failure development and risk using metabolomic profiling
MacLeod, K. (Investigator), Mordi, I. (Investigator) & Read, K. (Investigator)
1/04/25 → 30/09/26
Project: Research
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AAV-Mediated Gene Transfer to the 8HUM Mouse Model for Study of Population-Specific Drug Metabolism
MacLeod, K. (Investigator) & Read, K. (Investigator)
Project: Research
Research output
- 22 Article
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Untargeted metabolomics for triaging of cytochrome b inhibitors during Chagas’ disease drug discovery
MacLeod, A. K. (Lead / Corresponding author), Tulloch, L. B., Tinti, M., Edwards, D., Wyllie, S. & Read, K. D., 20 Jan 2026, In: PLoS Neglected Tropical Diseases. 20, 1, 17 p., e0013917.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Downloads (Pure) -
Use of a cytochrome P450 humanized mouse model to refine schistosomiasis drug discovery
Davey, S. D., Forde-Thomas, J. E., Hulme, B. J., Lees, K., Costain, A. H., Evans, M., Rinaldi, G., Frame, L., Stojanovski, L., Simeons, F. R. C., Tavendale, A., MacLeod, A. K., Pichon, R., Lee, Y. H., Polak, O., Chalmers, I. W., Dankwa, B., Odhiambo, B. K., Guimaraes, V. H. & Hegarty, M. & 8 others, , 14 Apr 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 15, 12 p., e2600197123.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Application of a mouse model humanized for cytochrome P450–mediated drug metabolism to predict drug-drug interactions between a peptide and small molecule drugs
Kapelyukh, Y., Gabel-Jensen, C., MacLeod, A. K., Coquelin, K.-S. D., Stojanovski, L., Frame, L., Tavendale, A., Henderson, C. J., Read, K. D., Wolf, C. R. (Lead / Corresponding author) & Säll, C. (Lead / Corresponding author), Oct 2025, In: Drug Metabolism and Disposition. 53, 10, 14 p., 100153.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)22 Downloads (Pure) -
Humanization of Drug Metabolism in the Plasmodium berghei Mouse Model for Antimalarial Drug Discovery
MacLeod, A. K. (Lead / Corresponding author), Merino, C., Viera-Morilla, S., Frame, L., Tavendale, A., Duncan, C., Ferguson, L., Pinto, E. G., Simeons, F. R. C., Gomez-Jimenez, V., García, A. B., Riley, J., Shishikura, Y., Santos Martínez-Martínez, M., Wolf, C. R. & Read, K. D. (Lead / Corresponding author), 12 Dec 2025, In: ACS Infectious Diseases. 11, 12, p. 3529-3541 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Downloads (Pure) -
The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals
Henderson, C. J., McLaren, A. W., MacLeod, A. K., Lin, D., Cameron, A. R., Chatham, L. R., Moggs, J., Inesta-Vaquera, F., Thomson, J. P., Meehan, R. R., Chakravarty, P., Schwarz, M. & Wolf, C. R. (Lead / Corresponding author), May 2025, In: Archives of Toxicology. 99, 5, p. 2197-2210 14 p., 109464.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)49 Downloads (Pure)