Spinelli, Laura

Dr

  • 214 Citations
  • 4 h-Index
20102019
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Fingerprint Dive into the research topics where Laura Spinelli is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 32 Similar Profiles
PTEN Phosphohydrolase Medicine & Life Sciences
Phosphoric Monoester Hydrolases Medicine & Life Sciences
Lipids Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Antigen Receptors Medicine & Life Sciences
Proteome Medicine & Life Sciences
T-cells Chemical Compounds

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Research Output 2010 2019

  • 214 Citations
  • 4 h-Index
  • 5 Article
  • 1 Chapter (peer-reviewed)
  • 1 Meeting abstract
1 Citation (Scopus)
24 Downloads (Pure)

Antigen receptor control of methionine metabolism in T cells

Sinclair, L. V., Howden, A., Brenes Murillo, A., Spinelli, L., Hukelmann, J., Macintyre, A. N., Liu, X., Thomson, S., Taylor, P., Rathmell, J. C., Locasale, J. W., Lamond, A. & Cantrell, D. A., 27 Mar 2019, In : eLife. 8, 29 p., e44210.

Research output: Contribution to journalArticle

Open Access
File
Antigen Receptors
T-cells
Metabolism
Methionine
T-Lymphocytes

Assays to measure PTEN lipid phosphatase activity in vitro from purified enzyme or immunoprecipitates

Spinelli, L. & Leslie, N. R., 2016, Protein tyrosine phosphatases: methods and protocols. Pulido, R. (ed.). New York: Springer , p. 95-105 11 p. (Methods in molecular biology; vol. 1447).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

PTEN Phosphohydrolase
Lipids
Enzymes
Phosphoric Monoester Hydrolases
Biological Phenomena
36 Citations (Scopus)

Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromes

Spinelli, L., Black, F. M., Berg, J. N., Eickholt, B. J. & Leslie, N. R., Feb 2015, In : Journal of Medical Genetics. 52, 2, p. 128-134 7 p.

Research output: Contribution to journalArticle

Multiple Hamartoma Syndrome
Autistic Disorder
Aptitude
Mutation
Neoplasms
41 Citations (Scopus)

PTEN inhibitors: an evaluation of current compounds

Spinelli, L., Lindsay, Y. E. & Leslie, N. R., Jan 2015, In : Advances in Biological Regulation. 57, p. 102-111 10 p.

Research output: Contribution to journalArticle

Phosphoric Monoester Hydrolases
Enzymes
Non-Receptor Type 6 Protein Tyrosine Phosphatase
Vanadates
Reducing Agents
61 Citations (Scopus)

PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity

Tibarewal, P., Zilidis, G., Spinelli, L., Schurch, N., Maccario, H., Gray, A., Perera, N. M., Davidson, L., Barton, G. J. & Leslie, N. R., 2012, In : Science Signaling. 5, 213, p. ra18

Research output: Contribution to journalArticle

PTEN Phosphohydrolase
Phosphoric Monoester Hydrolases
Gene expression
Tumors
Phenotype