Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Modelling TDP-43-induced aging in Drosophila melanogaster
McGurk, L. (Investigator)
1/12/23 → 31/05/26
Project: Research
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Blocking TDP-43 From Accumulating In The Cytoplasm As A Therapeutic Strategy For ALS
McGurk, L. (Investigator)
1/12/23 → 30/11/25
Project: Research
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Interrogating Tankyrase-mediated Control of Neuronal Degeneration in Frontotemporal Dementia (Dementia Research Leader Fellowship) (Outline) & Full
Alessi, D. (Investigator), Ashford, M. (Investigator), Davies, P. (Investigator), McGurk, L. (Investigator) & Storey, K. (Investigator)
2/10/23 → 1/10/28
Project: Research
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RNA Modifications in Frontotemporal Dementia and Motor Neuron Disease (Bridge Fund)
McGurk, L. (Investigator)
1/01/23 → 3/05/24
Project: Research
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Defining Novel Therapeutic Targets for TDP43 Associated Neurodegenerative Disease (Springboard Fellowship)
McGurk, L. (Investigator)
28/07/20 → 27/11/23
Project: Research
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Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology
François-Moutal, L., Scott, D. D., Ambrose, A. J., Zerio, C. J., Rodriguez-Sanchez, M., Dissanayake, K., May, D. G., Carlson, J. M., Barbieri, E., Moutal, A., Roux, K. J., Shorter, J., Khanna, R., Barmada, S. J., McGurk, L. & Khanna, M. (Lead / Corresponding author), 17 May 2022, In: Scientific Reports. 12, 14 p., 8140.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)449 Downloads (Pure) -
Heat Shock Protein Grp78/BiP/HspA5 Binds Directly to TDP-43 and Mitigates Toxicity Associated with Neurodegenerative Disease Pathology
François-Moutal, L., Scott, D., Ambrose, A., Zerio, C., Dissanayake, K., Danielle May, Carlson, J., Barbieri, E., Moutal, A., Roux, K., Shorter, J., Khanna, R., Barmada, S., McGurk, L. (Lead / Corresponding author) & Khanna, M. (Lead / Corresponding author), 8 Dec 2021, Research Square, 38 p.Research output: Working paper/Preprint › Preprint
File98 Downloads (Pure) -
Liquid-Liquid Phase Separation in Physiology and Pathophysiology of the Nervous System
Hayashi, Y. (Lead / Corresponding author), Ford, L. K., Fioriti, L., McGurk, L. & Zhang, M., 3 Feb 2021, In: Journal of Neuroscience. 41, 5, p. 834-844 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile49 Citations (Scopus)368 Downloads (Pure) -
Toxicity of pathogenic ataxin-2 in Drosophila shows dependence on a pure CAG repeat sequence
McGurk, L., Rifai, O. M., Shcherbakova, O., Perlegos, A. E., Byrns, C. N., Carranza, F. R., Zhou, H. W., Kim, H.-J., Zhu, Y. & Bonini, N. M. (Lead / Corresponding author), 1 Oct 2021, In: Human Molecular Genetics. 30, 19, p. 1797-1810 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)366 Downloads (Pure) -
Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila
Deng, P., Khan, A., Jacobson, D., Sambrani, N., McGurk, L., Li, X., Jayasree, A., Hejatko, J., Shohat-Ophir, G., O'Connell, M. A., Li, J. B. & Keegan, L. P., 27 Mar 2020, In: Nature Communications. 11, 1, p. 1580 1580.Research output: Contribution to journal › Article › peer-review
Open AccessFile45 Citations (Scopus)170 Downloads (Pure)
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Alzheimer's Society Volunteer science meeting
McGurk, L. (Member)
17 Dec 2024Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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External PhD examiner for the University of Aberdeen
McGurk, L. (Examiner)
Jun 2024Activity: Examination types › Examination
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The pathomechansims of ALS and FTD
McGurk, L. (Speaker)
Apr 2024Activity: Talk or presentation types › Invited talk
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UoD Patient and Public Involvement meeting with Moira Bayne Housing Options Scotland and Alison Clyde Generations Working Together.
McGurk, L. (Member)
24 Sept 2024Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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