Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Dive into the research topics where Leeanne McGurk is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Interrogating Tankyrase-mediated Control of Neuronal Degeneration in Frontotemporal Dementia (Dementia Research Leader Fellowship) (Outline) & Full
Alessi, D. (Investigator), Ashford, M. (Investigator), Davies, P. (Investigator), McGurk, L. (Investigator) & Storey, K. (Investigator)
2/10/23 → 1/10/28
Project: Research
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Modelling TDP-43-induced aging in Drosophila melanogaster
McGurk, L. (Investigator)
1/12/23 → 31/05/26
Project: Research
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Blocking TDP-43 From Accumulating In The Cytoplasm As A Therapeutic Strategy For ALS
McGurk, L. (Investigator)
1/12/23 → 30/11/25
Project: Research
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RNA Modifications in Frontotemporal Dementia and Motor Neuron Disease (Bridge Fund)
McGurk, L. (Investigator)
1/01/23 → 3/05/24
Project: Research
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Defining Novel Therapeutic Targets for TDP43 Associated Neurodegenerative Disease (Springboard Fellowship)
McGurk, L. (Investigator)
28/07/20 → 27/11/23
Project: Research
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Aberrant NSUN1 Activity Connects m5C RNA Modification to TDP-43 Neurotoxicity in ALS/FTD
Parra-Torres, M., Dissanayake, K., Gray, J. A., Langlands, A. J., Kucuk, R., Gierlinski, M., Troakes, C., King, A. & McGurk, L. (Lead / Corresponding author), Jan 2026, In: Life Science Alliance. 9, 1, 25 p., e202503297.Research output: Contribution to journal › Article › peer-review
Open AccessFile39 Downloads (Pure) -
Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology
François-Moutal, L., Scott, D. D., Ambrose, A. J., Zerio, C. J., Rodriguez-Sanchez, M., Dissanayake, K., May, D. G., Carlson, J. M., Barbieri, E., Moutal, A., Roux, K. J., Shorter, J., Khanna, R., Barmada, S. J., McGurk, L. & Khanna, M. (Lead / Corresponding author), 17 May 2022, In: Scientific Reports. 12, 14 p., 8140.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Link opens in a new tab Citations (Scopus)737 Downloads (Pure) -
Heat Shock Protein Grp78/BiP/HspA5 Binds Directly to TDP-43 and Mitigates Toxicity Associated with Neurodegenerative Disease Pathology
François-Moutal, L., Scott, D., Ambrose, A., Zerio, C., Dissanayake, K., Danielle May, Carlson, J., Barbieri, E., Moutal, A., Roux, K., Shorter, J., Khanna, R., Barmada, S., McGurk, L. (Lead / Corresponding author) & Khanna, M. (Lead / Corresponding author), 8 Dec 2021, Research Square, 38 p.Research output: Working paper/Preprint › Preprint
File153 Downloads (Pure) -
Liquid-Liquid Phase Separation in Physiology and Pathophysiology of the Nervous System
Hayashi, Y. (Lead / Corresponding author), Ford, L. K., Fioriti, L., McGurk, L. & Zhang, M., 3 Feb 2021, In: Journal of Neuroscience. 41, 5, p. 834-844 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile67 Link opens in a new tab Citations (Scopus)613 Downloads (Pure) -
Toxicity of pathogenic ataxin-2 in Drosophila shows dependence on a pure CAG repeat sequence
McGurk, L., Rifai, O. M., Shcherbakova, O., Perlegos, A. E., Byrns, C. N., Carranza, F. R., Zhou, H. W., Kim, H.-J., Zhu, Y. & Bonini, N. M. (Lead / Corresponding author), 1 Oct 2021, In: Human Molecular Genetics. 30, 19, p. 1797-1810 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Link opens in a new tab Citations (Scopus)522 Downloads (Pure)
Datasets
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Project PXD070093 NSUN1-m5C is linked to TDP-43 neurotoxicity
McGurk, L. (Creator), EMBL-EBI, 3 Nov 2025
https://www.ebi.ac.uk/pride/archive/projects/PXD070093
Dataset
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Measurements of C3402 methylation in the 28S rRNA in Drosophila
Gierlinski, M. (Creator) & McGurk, L. (Creator), EMBL-EBI, 1 Oct 2025
DOI: 10.6019/S-BSST2213
Dataset
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Management of RIPPLE: Researchers Involving the Public at Pre-application, Learn and Embed
Davies, P. (Member), Cameron, A. (Organiser), Patrick, S. (Organiser), Wasim, S. (Organiser), McGurk, L. (Member), Bulgarelli, D. (Member) & Goodburn, J. (Member)
1 Jan 2026 → 30 Jun 2027Activity: Other activity types › Other
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RIPPLE: Researchers Involving the Public at Pre-application, Learn and Embed
Davies, P. (Contributor), Cameron, A. (Contributor), Patrick, S. (Contributor), McGurk, L. (Contributor) & Bulgarelli, D. (Contributor)
1 Jan 2026 → 30 Jun 2027Activity: Other activity types › Funding - grants and income which support research related activities
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Defining How Tankyrase Functions With TDP-43 In ALS Disease Progression.
McGurk, L. (Member)
1 Dec 2025 → 30 Nov 2026Activity: Other activity types › Funding - grants and income which support research related activities
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MND Awareness Day and fundraiser at BridgeFM Hospital Radio
McGurk, L. (Interviewee)
19 Nov 2025Activity: Other activity types › Public engagement and outreach - media article or participation
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