Projects per year
Dr Kang gained her bachelor’s degree in Chemistry from University of Science and Technology of China in 2001 and moved to the US to continue her graduate school at Case Western Reserve University in Cleveland, Ohio. Dr Kang successfully defended her PhD thesis entitled “Chronic ethanol consumption disrupts both lipid and glucose homeostasis in rat adipose tissue” under the supervision of Professor Laura Nagy in 2007.
Dr Kang had her postdoctoral training with Professor David Wasserman at Vanderbilt University and was appointed as a research faculty member of Vanderbilt University Medical Centre in 2012. She was also the Managing Director of the Metabolic Pathophysiology Core of the Vanderbilt Mouse Metabolic Phenotyping Centre between 2012 and 2014.
Dr Kang moved to the UK and joined the faculty of the University of Dundee in April 2014. In this role, Dr Kang is establishing her independent research on understanding the pathogenesis of insulin resistance, focusing on studying the role of extracellular matrix (ECM) remodelling.
My research focuses on understanding the pathogenesis of insulin resistance. Emerging evidence suggests that the extracellular matrix (ECM) is of great potential significance in metabolic regulation and possibly is of pivotal significance for all metabolic diseases. By studying mice with specific mutations or mice overexpressing specific genes, my primary research interest centres on understanding the role of ECM remodelling in the pathogenesis of insulin resistance and identifying novel and cost-effective ECM-centric therapeutic targets for insulin resistance and type 2 diabetes. Insulin action in conscious, unstressed mice is studied by the hyperinsulinemic-euglycemic clamp technique. The research that is ongoing in my lab will provide new opportunities to explore therapeutics for insulin resistance and type 2 diabetes.
- Parmacology of Diabetes Treatment
- BSc Medical Sciences
- BMSc Cardiovascular and Diabetes
- PhD/MSc student supervision
- BSc honour projects
- BMSc research projects
- Summer projects
Generating Evidence that RABEP2 is a Novel GSK3 Substrate that Represents a Single Therapeutic Target to Reduce Both Hyperglycemia and Microvascular Disease in Diabetes (joint with Glasgow Uni)
1/06/20 → 31/05/23
1/09/19 → 29/02/20
Adipocyte Integrin-Linked Kinase Plays a Key Role in the Development of Diet-Induced Adipose Insulin Resistance in Male MiceBugler-Lamb, A. R., Hasib, A., Weng, X., Hennayake, C. K., Lin, C., McCrimmon, R. J., Stimson, R. H., Ashford, M. L. J., Wasserman, D. H. & Kang, L., Jul 2021, In: Molecular Metabolism. 49, 13 p., 101197.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile7 Downloads (Pure)
Kang, L., Wang, X., Sun, X., Mo, X., Tian, H., Pearson, E., Meng, W. & Li, S., 3 Jan 2020, In: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 12, p. 2819-2828 10 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile1 Citation (Scopus)21 Downloads (Pure)
Weng, X., Lin, D., Huang, J. T. J., Stimson, R. H., Wasserman, D. H. & Kang, L., 10 Aug 2020, In: International Journal of Molecular Sciences. 21, 16, 13 p., 5738.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile3 Citations (Scopus)16 Downloads (Pure)
CD44 contributes to hyaluronan-mediated insulin resistance in skeletal muscle of high fat-fed C57BL/6 miceHasib, A., Hennayake, C., Bracy, D. P., Bugler-Lamb, A-R., Lantier, L., Khan, F., Ashford, M., McCrimmon, R., Wasserman, D. H. & Kang, L., Dec 2019, In: American Journal of Physiology, Endocrinology and Metabolism. 317, 6, p. E973-E983 11 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile3 Citations (Scopus)33 Downloads (Pure)
Cytochrome P450 Epoxygenase-Derived Epoxyeicosatrienoic Acids Contribute to Insulin Sensitivity in Mice and in HumansGangadhariah, M. H., Dieckmann, B. W., Lantier, L., Kang, L., Wasserman, D. H., Chiusa, M., Caskey, C. F., Dickerson, J., Luo, P., Capdevila, J. H., Imig, J. D., Yu, C., Pozzi, A. & Luther, J. M., Jun 2017, In: Diabetologia. 60, 6, p. 1066-1075
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile17 Citations (Scopus)175 Downloads (Pure)
Matthew Jarron (Organiser), Amy Cameron (Organiser), Nicola Morrice (Contributor), Chim Lang (Contributor), Agathe Lermant (Contributor), Cara Nicholson (Contributor), Colin Henderson (Contributor), Ros Langston (Member), Laureano de la Vega (Member), Gillian Smith (Contributor), Daniella Cavellini (Contributor), Andrew Evans (Contributor), Jane Dickson (Contributor), Jacqueline Eccles (Contributor), Ola Epemolu (Contributor), Kevin Read (Contributor), Mattie Pawlowic (Contributor), Matthew Taylor (Contributor), Sarah McKim (Contributor), Henry McSorley (Contributor), Peter Mossey (Contributor), Susan Wyllie (Contributor), Niamh Nic Daeid (Contributor), Seaneen McDougall (Contributor), Ailsa Mackintosh (Contributor), Ali Floyd (Contributor), Catharine Goddard (Contributor), Li Kang (Contributor), James Gemmill (Contributor) & Rolf Black (Contributor)Nov 2020
Activity: Other activity types › Other
Li Kang (Member)2020 → …
Activity: Membership types › Membership of committee