Kang, Li

Dr

  • 1530 Citations
  • 16 h-Index
20062022
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Personal profile

Biography

Dr Kang gained her bachelor’s degree in Chemistry from University of Science and Technology of China in 2001 and moved to the US to continue her graduate school at Case Western Reserve University in Cleveland, Ohio. Dr Kang successfully defended her PhD thesis entitled “Chronic ethanol consumption disrupts both lipid and glucose homeostasis in rat adipose tissue” under the supervision of Professor Laura Nagy in 2007.

Dr Kang had her postdoctoral training with Professor David Wasserman at Vanderbilt University and was appointed as a research faculty member of Vanderbilt University Medical Centre in 2012. She was also the Managing Director of the Metabolic Pathophysiology Core of the Vanderbilt Mouse Metabolic Phenotyping Centre between 2012 and 2014.

Dr Kang moved to the UK and joined the faculty of the University of Dundee in April 2014. In this role, Dr Kang is establishing her independent research on understanding the pathogenesis of insulin resistance, focusing on studying the role of extracellular matrix (ECM) remodelling.

Research interests

My research focuses on understanding the pathogenesis of insulin resistance. Emerging evidence suggests that the extracellular matrix (ECM) is of great potential significance in metabolic regulation and possibly is of pivotal significance for all metabolic diseases. By studying mice with specific mutations or mice overexpressing specific genes, my primary research interest centres on understanding the role of ECM remodelling in the pathogenesis of insulin resistance and identifying novel and cost-effective ECM-centric therapeutic targets for insulin resistance and type 2 diabetes. Insulin action in conscious, unstressed mice is studied by the hyperinsulinemic-euglycemic clamp technique. The research that is ongoing in my lab will provide new opportunities to explore therapeutics for insulin resistance and type 2 diabetes.

Teaching

Lecture teaching:

  • Parmacology of Diabetes Treatment
  • BSc Medical Sciences
  • BMSc Cardiovascular and Diabetes

Research projects:

  • PhD/MSc student supervision
  • BSc honour projects
  • BMSc research projects
  • Summer projects

Fingerprint Dive into the research topics where Li Kang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Insulin Resistance Medicine & Life Sciences
Fats Medicine & Life Sciences
Glucose Medicine & Life Sciences
Insulin Medicine & Life Sciences
Muscles Medicine & Life Sciences
Skeletal Muscle Medicine & Life Sciences
Diet Medicine & Life Sciences
Extracellular Matrix Medicine & Life Sciences

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Projects 2014 2022

Research Output 2006 2019

  • 1530 Citations
  • 16 h-Index
  • 25 Article
  • 1 Comment/debate
  • 1 Review article
Hyaluronic Acid
Inbred C57BL Mouse
Insulin Resistance
Skeletal Muscle
Fats
8 Citations (Scopus)
119 Downloads (Pure)

Cytochrome P450 Epoxygenase-Derived Epoxyeicosatrienoic Acids Contribute to Insulin Sensitivity in Mice and in Humans

Gangadhariah, M. H., Dieckmann, B. W., Lantier, L., Kang, L., Wasserman, D. H., Chiusa, M., Caskey, C. F., Dickerson, J., Luo, P., Capdevila, J. H., Imig, J. D., Yu, C., Pozzi, A. & Luther, J. M., Jun 2017, In : Diabetologia. 60, 6, p. 1066-1075

Research output: Contribution to journalArticle

Open Access
File
Cytochrome P-450 Enzyme System
Insulin Resistance
Acids
Blood Vessels
Glucose
30 Citations (Scopus)
78 Downloads (Pure)

Adipose extracellular matrix remodelling in obesity and insulin resistance

Lin, D., Chun, T-H. & Kang, L., 1 Nov 2016, In : Biochemical Pharmacology. 119, p. 8-16 9 p.

Research output: Contribution to journalComment/debate

Open Access
File
Extracellular Matrix
Insulin Resistance
Adipose Tissue
Obesity
Insulin
11 Citations (Scopus)
129 Downloads (Pure)

Integrin-linked kinase in muscle is necessary for the development of insulin resistance in diet-induced obese mice

Kang, L., Mokshagundam, S., Reuter, B., Lark, D. S., Sneddon, C. C., Hennayake, C., Williams, A. S., Bracy, D. P., James, F. D., Pozzi, A., Zent, R. & Wasserman, D. H., 1 Jun 2016, In : Diabetes. 65, 6, p. 1590-1600 11 p.

Research output: Contribution to journalArticle

Open Access
File
Obese Mice
Insulin Resistance
Diet
Muscles
Integrins
11 Citations (Scopus)
120 Downloads (Pure)

Enhanced mitochondrial superoxide scavenging does not Improve muscle insulin action in the high fat-fed mouse

Lark, D. S., Kang, L., Lustig, M. E., Bonner, J. S., James, F. D., Neufer, P. D. & Wasserman, D. H., 19 May 2015, In : PLoS ONE. 10, 5, 11 p., e0126732.

Research output: Contribution to journalArticle

Open Access
File
Scavenging
Superoxides
superoxide anion
Muscle
insulin

Activities 2019 2019

  • 1 Schools engagement

Leuchars Primary School (3)

Colin Henderson (Member), Frances Fuller-Pace (Member), Amy Rogers (Member), Li Kang (Member), Jennifer Kennedy (Member)
26 Apr 2019

Activity: Other activity typesSchools engagement