Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Research output
- 7 Article
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Humanization of Drug Metabolism in the Plasmodium berghei Mouse Model for Antimalarial Drug Discovery
MacLeod, A. K. (Lead / Corresponding author), Merino, C., Viera-Morilla, S., Frame, L., Tavendale, A., Duncan, C., Ferguson, L., Pinto, E. G., Simeons, F. R. C., Gomez-Jimenez, V., García, A. B., Riley, J., Shishikura, Y., Santos Martínez-Martínez, M., Wolf, C. R. & Read, K. D. (Lead / Corresponding author), 12 Dec 2025, In: ACS Infectious Diseases. 11, 12, p. 3529-3541 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Downloads (Pure) -
Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism
MacLeod, A. K., Coquelin, K.-S., Huertas, L., Simeons, F. R. C., Riley, J., Casado, P., Guijarro, L., Casanueva, R., Frame, L., Pinto, E. G., Ferguson, L., Duncan, C., Mutter, N., Shishikura, Y., Henderson, C. J., Cebrian, D., Wolf, C. R. & Read, K. D. (Lead / Corresponding author), 13 Feb 2024, In: Proceedings of the National Academy of Sciences. 121, 7, p. 1-12 12 p., 2315069121.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Link opens in a new tab Citations (Scopus)209 Downloads (Pure) -
Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy
Caldwell, N., Peet, C., Miller, P., Colon, B., Taylor, M., Cocco, M., Dawson, A., Lukac, I., Teixeira, J. E., Robinson, L., Frame, L., Seizova, S., Damerow, S., Tamaki, F., Post, J., Riley, J., Mutter, N., Hanna, J. C., Ferguson, L. & Hu, X. & 13 others, , 23 Oct 2024, In: Science Translational Medicine. 16, 770, p. 1-12 12 p., eadm8631.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Link opens in a new tab Citations (Scopus)391 Downloads (Pure) -
Rational Exploration of 2,4-Diaminopyrimidines as DHFR Inhibitors Active against Mycobacterium abscessus and Mycobacterium avium, Two Emerging Human Pathogens
Andrade Meirelles, M., Almeida, V. M., Sullivan, J. R., de Toledo, I., dos Reis, C. V., Cunha, M. R., Zigweid, R., Shim, A., Sankaran, B., Woodward, E. L., Seibold, S., Liu, L., Mian, M. R., Battaile, K. P., Riley, J., Duncan, C., Simeons, F. R. C., Ferguson, L., Joji, H. & Read, K. D. & 5 others, , 14 Nov 2024, In: Journal of Medicinal Chemistry. 67, 21, p. 19143-19164 22 p.Research output: Contribution to journal › Article › peer-review
5 Link opens in a new tab Citations (Scopus) -
Structure Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors
Thomas, M. G., McGonagle, K., Rowland, P., Robinson, D. A., Dodd, P. G., Camino-Díaz, I., Campbell, L., Cantizani, J., Castañeda, P., Conn, D., Craggs, P. D., Edwards, D., Ferguson, L., Fosberry, A., Frame, L., Goswami, P., Hu, X., Korczynska, J., MacLean, L. & Martin, J. & 21 others, , 10 Aug 2023, In: Journal of Medicinal Chemistry. 66, 15, p. 10413-10431 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Link opens in a new tab Citations (Scopus)314 Downloads (Pure)
Prizes
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Industry and Academic Collaboration Award
De Rycker, M. (Recipient), Gilbert, I. (Recipient), Read, K. (Recipient), Wyllie, S. (Recipient), Wyatt, P. (Recipient), Gray, D. (Recipient), Thomas, M. (Recipient), Brand, S. (Recipient), McGonagle, K. (Recipient), Dodd, P. (Recipient), Dunne, J. (Recipient), MacLean, L. (Recipient), Thomas, J. (Recipient), Manthri, S. (Recipient), Paterson, C. (Recipient), Stojanovski, L. (Recipient), Pinto, E. (Recipient), Ferguson, L. (Recipient), Simeons, F. (Recipient), Torrie, L. (Recipient), Robinson, D. (Recipient), Riley, J. (Recipient), Frame, L. (Recipient), Garcia Sanchez, M. (Recipient), Da Silva Pacheco, J. (Recipient), Miles, T. (Recipient), Fiandor, J. M. (Recipient), Martin, J. J. (Recipient), Marco, M. (Recipient), Gonzalez, S. (Recipient), Cantizani, J. (Recipient), Cotillo, I. (Recipient) & Manzano, M. P. (Recipient), 12 Apr 2023
Prize: Prize (including medals and awards)
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Maryfield Family Food and Fun Summer 2025
Floyd, A. (Organiser), Goddard, C. (Participant), Joji, H. (Participant), Altmann, S. (Participant), Ferguson, L. (Participant), Farrell, S. (Participant), Doran, H. (Participant), Mackintosh, A. (Participant) & Morriss, C. (Participant)
10 Jul 2025Activity: Other activity types › Public engagement and outreach - festival/exhibition
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Magnificent Microbes 2024
Hardee, E. (Organiser), Floyd, A. (Organiser), Mackintosh, A. (Organiser), Stanley-Wall, N. (Organiser), Arnaouteli, S. (Participant), Bergkessel, M. (Participant), Bonsall, A. (Participant), Bulgarelli, D. (Participant), Coulthurst, S. (Participant), Dicker, A. (Participant), Dorfmueller, H. (Participant), Donnelly, H. (Participant), Ferguson, L. (Participant), Hemsley, C. (Participant), Hernandez, R. (Participant), Hull, R. (Participant), Keddy, C. (Participant), Mehta, N. (Participant), Mol Avelar Tamaki, G. (Participant), Neill, D. (Participant), Siddiqui, R. (Participant), Singh, V. (Participant), Tamaki, F. (Participant), Wood, A. (Participant), Prescott, A. (Contributor), Wasim, S. (Contributor) & Arnton, K. (Contributor)
9 Mar 2024Activity: Participating in or organising an event types › Festival/Exhibition