Sinclair, Linda


  • 1453 Citations
  • 14 h-Index
If you made any changes in Pure these will be visible here soon.

Fingerprint Dive into the research topics where Linda Sinclair is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 13 Similar Profiles
T-Lymphocytes Medicine & Life Sciences
T-cells Chemical Compounds
Antigen Receptors Medicine & Life Sciences
Proteome Medicine & Life Sciences
Amino Acids Medicine & Life Sciences
Cell Differentiation Medicine & Life Sciences
Amino Acid Transport System L Chemical Compounds
Interleukin-2 Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2008 2019

  • 1453 Citations
  • 14 h-Index
  • 20 Article
  • 1 Meeting abstract
8 Citations (Scopus)
69 Downloads (Pure)

Antigen receptor control of methionine metabolism in T cells

Sinclair, L. V., Howden, A., Brenes Murillo, A., Spinelli, L., Hukelmann, J., Macintyre, A. N., Liu, X., Thomson, S., Taylor, P., Rathmell, J. C., Locasale, J. W., Lamond, A. & Cantrell, D. A., 27 Mar 2019, In : eLife. 8, 29 p., e44210.

Research output: Contribution to journalArticle

Open Access
Antigen Receptors
2 Citations (Scopus)

Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses

O'Brien, A., Loftus, R. M., Pisarska, M. M., Tobin, L. M., Bergin, R., Wood, N. A. W., Foley, C., Mat, A., Tinley, F. C., Bannan, C., Sommerville, G., Veerapen, N., Besra, G. S., Sinclair, L. V., Moynagh, P. N., Lynch, L., Finlay, D. K., O'Shea, D. & Hogan, A. E., 15 Jun 2019, In : Journal of Immunology. 202, 12, p. 3404-3411 8 p.

Research output: Contribution to journalArticle

Large Neutral Amino Acid-Transporter 1
RNA Sequence Analysis
mechanistic target of rapamycin complex 1
1 Citation (Scopus)
Cell Differentiation
Mass Spectrometry
24 Citations (Scopus)
101 Downloads (Pure)

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

Loftus, R. M., Assmann, N., Kedia-Mehta, N., O'Brien, K. L., Garcia, A., Gillespie, C., Hukelmann, J. L., Oefner, P. J., Lamond, A. I., Gardiner, C. M., Dettmer, K., Cantrell, D. A., Sinclair, L. V. & Finlay, D. K., 14 Jun 2018, In : Nature Communications. 9, 1, p. 1-15 15 p., 2341.

Research output: Contribution to journalArticle

Open Access
Natural Killer Cells
amino acids
11 Citations (Scopus)
172 Downloads (Pure)

Interleukin-2 shapes the cytotoxic T cell proteome and immune environment sensing programs

Rollings, C., Sinclair, L., Brady, H. J. M., Cantrell, D. & Ross, S., 17 Apr 2018, In : Science Signaling. 11, 526, p. 1-16 16 p., eaap8112.

Research output: Contribution to journalArticle

Open Access
Cytotoxic T-Lymphocytes