Davidson, Lindsay

Dr

  • 696 Citations
  • 11 h-Index
20062018
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Research Output 2006 2018

  • 696 Citations
  • 11 h-Index
  • 13 Article
  • 1 Meeting abstract
2018
5 Citations (Scopus)
48 Downloads (Pure)

Neural differentiation, selection and transcriptomic profiling of human neuromesodermal progenitor-like cells in vitro

Verrier, L., Davidson, L., Gierlinski, M., Dady, A. & Storey, K., 12 Jul 2018, In : Development. 145, 16, 10 p., dev166215.

Research output: Contribution to journalArticle

Open Access
File
Stem Cells
Spinal Cord
Embryonic Structures
Clustered Regularly Interspaced Short Palindromic Repeats
Population
2017
4 Citations (Scopus)
113 Downloads (Pure)
Open Access
File
Regulator Genes
Protein Isoforms
Genes
Specifications
Pluripotent Stem Cells
2016
11 Citations (Scopus)
121 Downloads (Pure)

mRNA Cap methylation in pluripotency and differentiation

Grasso, L., Suska, O., Davidson, L., Gonatopoulos-Pournatzis, T., Williamson, R., Wasmus, L., Wiedlich, S., Peggie, M., Stavridis, M. P. & Cowling, V. H., 2 Aug 2016, In : Cell Reports. 16, 5, p. 1352-1365 14 p.

Research output: Contribution to journalArticle

Open Access
File
Methylation
Random access storage
Messenger RNA
Genes
Gene expression
2013
61 Citations (Scopus)

Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells

Ulvestad, M., Nordell, P., Asplund, A., Rehnström, M., Jacobsson, S., Holmgren, G., Davidson, L., Brolén, G., Edsbagge, J., Björquist, P., Küppers-Munther, B. & Andersson, T. B., 1 Sep 2013, In : Biochemical Pharmacology. 86, 5, p. 691-702 12 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Stem cells
Hepatocytes
Cytochrome P-450 Enzyme System
Enzymes
2012
68 Citations (Scopus)

PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity

Tibarewal, P., Zilidis, G., Spinelli, L., Schurch, N., Maccario, H., Gray, A., Perera, N. M., Davidson, L., Barton, G. J. & Leslie, N. R., 2012, In : Science Signaling. 5, 213, p. ra18

Research output: Contribution to journalArticle

PTEN Phosphohydrolase
Phosphoric Monoester Hydrolases
Gene expression
Tumors
Phenotype
2010

Regulation of mammary epithelial architecture by PTEN

Lim, J. C., Davidson, L., Weerasinghe, N. R., Zilidis, G., Tibarewal, P., Spinelli, L. & Leslie, N. R., 2010, In : Breast Cancer Research. 12, p. S3-S3 1 p., P4.

Research output: Contribution to journalMeeting abstract

78 Citations (Scopus)

Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN

Davidson, L., Maccario, H., Perera, N. M., Yang, X., Spinelli, L., Tibarewal, P., Glancy, B., Gray, A., Weijer, C. J., Downes, C. P. & Leslie, N. R., 4 Feb 2010, In : Oncogene. 29, 5, p. 687-697 11 p.

Research output: Contribution to journalArticle

2009
29 Citations (Scopus)

Identification and specific localization of tyrosine-phosphorylated proteins in Trypanosoma brucei

Nett, I. R. E., Davidson, L., Lamont, D. & Ferguson, M. A. J., Apr 2009, In : Eukaryotic Cell. 8, 4, p. 617-626 10 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

The significance of PTEN's protein phosphatase activity

Leslie, N. R., Maccario, H., Spinelli, L. & Davidson, L., 2009, In : Advances in Enzyme Regulation. 49, 1, p. 190-196 7 p.

Research output: Contribution to journalArticle

PTEN Phosphohydrolase
Phosphatidylinositol 4,5-Diphosphate
Mouse Pik3cg protein
Phosphatidylinositol 3-Kinases
Phosphoprotein Phosphatases
2008
163 Citations (Scopus)

Understanding PTEN regulation: PIP, polarity and protein stability

Leslie, N. R., Batty, I. H., Maccario, H., Davidson, L. & Downes, C. P., 15 Sep 2008, In : Oncogene. 27, 41, p. 5464-5476 13 p.

Research output: Contribution to journalArticle

Protein Stability
Phosphorylation
PTEN Phosphohydrolase
Lipids
Neoplasms
2007
31 Citations (Scopus)

Loss of PTEN selectively desensitizes upstream IGF1 and insulin signaling

Lackey, J., Barnett, J., Davidson, L., Batty, I. H., Leslie, N. R. & Downes, C. P., Nov 2007, In : Oncogene. 26, 50, p. 7132-7142 11 p.

Research output: Contribution to journalArticle

Somatomedins
Phosphatidylinositol 3-Kinases
Insulin
Neoplasms
PTEN Phosphohydrolase
102 Citations (Scopus)

PTEN is destabilized by phosphorylation on Thr366

Maccario, H., Perera, N. M., Davidson, L., Downes, C. P. & Leslie, N. R., 1 Aug 2007, In : Biochemical Journal. 405, 3, p. 439-444 6 p.

Research output: Contribution to journalArticle

PTEN Phosphohydrolase
Phosphorylation
Glycogen Synthase Kinase 3
Mutation
Tumors
20 Citations (Scopus)

Stimulation of PI 3-kinase signaling via inhibition of the tumor suppressor phosphatase, PTEN

Downes, C. P., Ross, S., Maccario, H., Perera, N., Davidson, L. & Leslie, N. R., 2007, In : Advances in Enzyme Regulation. 47, p. 184-194 11 p.

Research output: Contribution to journalArticle

2006
88 Citations (Scopus)

Localization of agonist-sensitive PtdIns(3,4,5)P3 reveals a nuclear pool that is insensitive to PTEN expression

Lindsay, Y., McCoull, D., Davidson, L., Leslie, N. R., Fairservice, A., Gray, A., Lucocq, J. & Downes, C. P., Dec 2006, In : Journal of Cell Science. 119, 24, p. 5160-5168 9 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Cell Membrane
Swiss 3T3 Cells
PTEN Phosphohydrolase
Lipids