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Fulcher, Luke

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  • 40 Citations
  • 3 h-Index
20162019
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Casein Kinase I Chemical Compounds
Proteolysis Medicine & Life Sciences
Missiles Chemical Compounds
Proteins Medicine & Life Sciences
Spindle Apparatus Medicine & Life Sciences
Anchors Chemical Compounds
Cells Chemical Compounds
proteolysis Agriculture & Biology

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Research Output 2016 2019

  • 40 Citations
  • 3 h-Index
  • 4 Article
  • 1 Review article
1 Citation (Scopus)
134 Downloads (Pure)

Advances in targeted degradation of endogenous proteins

Roth, S., Fulcher, L. & Sapkota, G., 27 Apr 2019, In : Cellular and Molecular Life Sciences. 76, 14, p. 2761-2777 17 p.

Research output: Contribution to journalReview article

Open Access
File
Proteolysis
Proteins
Clustered Regularly Interspaced Short Palindromic Repeats
Gene Targeting
Protein Biosynthesis
15 Downloads (Pure)

FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning

Fulcher, L. J., He, Z., Mei, L., Macartney, T. J., Wood, N. T., Prescott, A. R., Whigham, A., Varghese, J., Gourlay, R., Ball, G., Clarke, R., Campbell, D., Maxwell, C. A. & Sapkota, G. P., 24 Jul 2019, In : EMBO Reports. p. 1-19 19 p., e47495.

Research output: Contribution to journalArticle

Open Access
File
Casein Kinase I
Spindle Apparatus
Phosphotransferases
Cells
Mitosis
11 Citations (Scopus)
85 Downloads (Pure)

The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms

Fulcher, L., Bozatzi, P., Tachie-Menson, T., Wu, K., Cummins, T. D., Bufton, J. C., Pinkas, D. M., Dunbar, K., Shrestha, S., Wood, N., Weidlich, S., Macartney, T., Varghese, J., Gourlay, R., Campbell, D., Dingwell, K. S., Smith, J. C., Bullock, A. N. & Sapkota, G., 22 May 2018, In : Science Signaling. 11, 531, eaao2341.

Research output: Contribution to journalArticle

Open Access
File
Casein Kinase I
Anchors
Protein Isoforms
Proteins
Protein-Serine-Threonine Kinases
14 Citations (Scopus)
86 Downloads (Pure)

Targeting endogenous proteins for degradation through the affinity-directed protein missile system

Fulcher, L. J., Hutchinson, L. D., Macartney, T. J., Turnbull, C. & Sapkota, G. P., 10 May 2017, In : Open Biology. 7, p. 1-11 11 p., 170066.

Research output: Contribution to journalArticle

Open Access
File
Missiles
Proteolysis
Degradation
Proteins
Ubiquitin-Protein Ligases
14 Citations (Scopus)
97 Downloads (Pure)

An Affinity-directed PROtein Missile (AdPROM) system for targeted proteolysis

Fulcher, L., Macartney, T., Bozatzi, P., Hornberger, A., Rojas-Fernandez, A. & Sapkota, G., 26 Oct 2016, In : Open Biology. 6, 10, p. 1-9 9 p., 160255.

Research output: Contribution to journalArticle

Open Access
File
Proteolysis
Missiles
proteolysis
Proteins
proteins