Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Mairi H McLean is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Identifying Novel Treatment Targets For Bile Acid Diarrhoea Through Interrogation Of Targeted Epithelial Barrier Disease Mechanisms And Discovery Science Proteomics In Human Gut Organoid Models - Joint with Imperial College, London
Arthur, S. (Investigator) & McLean, M. H. (Investigator)
1/09/23 → 28/02/26
Project: Research
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Defining Stromal Biology In The Pathogenesis Of Oesophageal Cancer To Create A Novel Biomarker Signature To Aid Diagnosis, Prognosis And Treatment Strategies
Kang, L. (Investigator), McLean, M. H. (Investigator) & Walsh, S. (Investigator)
15/05/23 → 14/11/24
Project: Research
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Interleukin-33 is a Novel Treatment Target for Inflammatory Bowel Disease (Transfer)
McLean, M. H. (Investigator)
Project: Research
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Assessing Interleukin-33 Effects On Human Eosinophils - A Mechanism In Fibrotic Diseases - Vacation Studentship
McLean, M. H. (Investigator)
Project: Research
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Defining the Role of Interleukin-33 in Gastrointestinal Fibrosis as a New Treatment Target for Crohn's Disease (PhD Studentship)
McLean, M. H. (Investigator) & McSorley, H. (Investigator)
Project: Research
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An investigation of the clinical impact and therapeutic relevance of a DNA damage immune response (DDIR) signature in patients with advanced gastroesophageal adenocarcinoma
Baxter, M. A. (Lead / Corresponding author), Spender, L. C., Cairns, D., Walsh, S., Oparka, R., Porter, R. J., Bray, S., Skinner, G., King, S., Turbitt, J., Collinson, D., Miedzybrodzka, Z. H., Jellema, G., Logan, G., Kennedy, R. D., Turkington, R. C., McLean, M. H., Swinson, D., Grabsch, H. I. & Lord, S. & 3 others, , May 2024, In: ESMO open. 9, 5, 12 p., 103450.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Downloads (Pure) -
IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium
Andrews, C., McLean, M. H., Hixon, J. A., Pontejo, S. M., Starr, T., Malo, C., Cam, M., Ridnour, L., Hickman, H., Steele-Mortimer, O., Wink, D. A., Young, H. A., McVicar, D. W., Li, W. & Durum, S. K. (Lead / Corresponding author), 20 Apr 2023, In: Frontiers in Immunology. 14, 9 p., 1021824.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)48 Downloads (Pure) -
Subcellular Epithelial HMGB1 Expression Is Associated with Colorectal Neoplastic Progression, Male Sex, Mismatch Repair Protein Expression, Lymph Node Positivity, and an ‘Immune Cold’ Phenotype Associated with Poor Survival
Porter, R. J., Murray, G. I., Hapca, S., Hay, A., Craig, S. G. .., Humphries, M. P., James, J. A., Salto-Tellez, M., Brice, D. P., Berry, S. H. & McLean, M. H. (Lead / Corresponding author), 20 Mar 2023, In: Cancers. 15, 6, 16 p., 1865.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)39 Downloads (Pure) -
British Society of Gastroenterology interim framework for addressing the COVID-19-related backlog in inflammatory bowel disease colorectal cancer surveillance
Churchhouse, A. M. D., Moffat, V. E. L., Selinger, C. P., Lamb, C. A., Thornton, M. J., Penman, I., Din, S. (Lead / Corresponding author) & Mowat, C., 5 Sept 2022, (E-pub ahead of print) In: Gut. 4 p., gutjnl-2022-328309.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile4 Citations (Scopus)58 Downloads (Pure) -
Clonal Transitions and Phenotypic Evolution in Barrett's Esophagus
Evans, J. A., Carlotti, E., Lin, M.-L., Hackett, R. J., Haughey, M. J., Passman, A. M., Dunn, L., Elia, G., Porter, R. J., Mclean, M. H., Hughes, F., Chinaleong, J., Woodland, P., Preston, S. L., Griffin, S. M., Lovat, L., Rodriguez-justo, M., Huang, W., Wright, N. A. & Jansen, M. & 1 others, , 1 Apr 2022, In: Gastroenterology. 162, 4, p. 1197-1209.e13 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)163 Downloads (Pure)
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Cutaneous Crohn's disease
McLean, M. H. (Member)
14 Sept 2023Activity: Talk or presentation types › Invited talk
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IBD biologics: current concepts and future developments
McLean, M. H. (Keynote speaker)
Sept 2022Activity: Talk or presentation types › Keynote
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Tenovus Scotland (External organisation)
McLean, M. H. (Member)
2022 → …Activity: Membership types › Membership of committee
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Current treatments in IBD and therapeutic pipeline
McLean, M. H. (Speaker)
May 2022Activity: Talk or presentation types › Keynote
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Academic Lead for the Tayside Tissue Biorepository
McLean, M. H. (Member)
2022 → …Activity: Other activity types › Other